메뉴 건너뛰기




Volumn 33, Issue 1, 1996, Pages 1-9

Therapeutic potential of anti-HIV immunotoxins

Author keywords

AIDS; Anti HIV immunotoxins; HIV; Immunotoxin

Indexed keywords

CD4 ANTIGEN DERIVATIVE; IMMUNOTOXIN; INTERLEUKIN 2 RECEPTOR; VIRUS ANTIGEN;

EID: 0030272992     PISSN: 01663542     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0166-3542(96)00995-3     Document Type: Article
Times cited : (20)

References (39)
  • 1
    • 0029062687 scopus 로고
    • Expression and characterization of CD4-IgG2, a novel heteroteramer that neutralizes primary HIV-1 isolates
    • Allaway, G.P., Davis-Bruno, K.L., Beaudry, G.A. et al. (1995) Expression and characterization of CD4-IgG2, a novel heteroteramer that neutralizes primary HIV-1 isolates. AIDS Res. Hum. Retroviruses 11, 533-539.
    • (1995) AIDS Res. Hum. Retroviruses , vol.11 , pp. 533-539
    • Allaway, G.P.1    Davis-Bruno, K.L.2    Beaudry, G.A.3
  • 2
    • 0027374447 scopus 로고
    • A phase I study of an anti-CD22-deglycosylated ricin A chain immunotoxin in the treatment of B-cell lymphomas resistant to conventional therapy
    • Amlot, P.L., Stone, M.J., Cunningham, D. et al. (1993) A phase I study of an anti-CD22-deglycosylated ricin A chain immunotoxin in the treatment of B-cell lymphomas resistant to conventional therapy. Blood 82, 2624-2633.
    • (1993) Blood , vol.82 , pp. 2624-2633
    • Amlot, P.L.1    Stone, M.J.2    Cunningham, D.3
  • 3
    • 0025225451 scopus 로고
    • Elimination of infectious human immunodeficiency virus from human T-cell cultures by synergistic action of CD4-Pseudomonas exotoxin and reverse transcriptase inhibitors
    • Ashorn, P., Moss, B., Weinstein, J.N. et al. (1990) Elimination of infectious human immunodeficiency virus from human T-cell cultures by synergistic action of CD4-Pseudomonas exotoxin and reverse transcriptase inhibitors. Proc. Natl. Acad. Sci. USA 87, 8889-8893.
    • (1990) Proc. Natl. Acad. Sci. USA , vol.87 , pp. 8889-8893
    • Ashorn, P.1    Moss, B.2    Weinstein, J.N.3
  • 4
    • 0025852258 scopus 로고
    • Anti-HIV activity of CD4-Pseudomonas exotoxin on infected primary human lymphocytes and monocyte/macrophages
    • Ashorn, P., Englund, G., Martin, M.A., Moss, B. and Berger, E.A. (1991) Anti-HIV activity of CD4-Pseudomonas exotoxin on infected primary human lymphocytes and monocyte/macrophages. J. Infect. Dis. 163, 703-709.
    • (1991) J. Infect. Dis. , vol.163 , pp. 703-709
    • Ashorn, P.1    Englund, G.2    Martin, M.A.3    Moss, B.4    Berger, E.A.5
  • 5
    • 0027410138 scopus 로고
    • Combined use of an immunotoxin and cyclosporine to prevent both activated and quiescent peripheral blood T cells from producing type 1 human immunodeficiency virus
    • Bell, K.D., Ramilo, O. and Vitetta, E.S. (1993) Combined use of an immunotoxin and cyclosporine to prevent both activated and quiescent peripheral blood T cells from producing type 1 human immunodeficiency virus. Proc. Natl. Acad. Sci. USA 90, 1411-1415.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 1411-1415
    • Bell, K.D.1    Ramilo, O.2    Vitetta, E.S.3
  • 6
    • 0029056343 scopus 로고
    • Expression of CD25 defines peripheral blood mononuclear cells with productive versus latent HIV infection
    • Borvak, J., Chou, C.-S., Bell, K., Van Dyke, G., Zola, H., Ramilio, O. and Vitetta, E.S. (1995) Expression of CD25 defines peripheral blood mononuclear cells with productive versus latent HIV infection. J. Immunol. 155, 3196-3204.
    • (1995) J. Immunol. , vol.155 , pp. 3196-3204
    • Borvak, J.1    Chou, C.-S.2    Bell, K.3    Van Dyke, G.4    Zola, H.5    Ramilio, O.6    Vitetta, E.S.7
  • 7
    • 0023784225 scopus 로고
    • Selective killing of HIV-infected cells by recombinant human CD4-Pseudomonas exotoxin hybrid protein
    • Chaudhary, V.K., Mizukami, T., Fuerst, T.R., FitzGerald, D.J., Moss, B., Pastan, I. and Berger, E.A. (1988) Selective killing of HIV-infected cells by recombinant human CD4-Pseudomonas exotoxin hybrid protein. Nature 335, 369-372.
    • (1988) Nature , vol.335 , pp. 369-372
    • Chaudhary, V.K.1    Mizukami, T.2    Fuerst, T.R.3    FitzGerald, D.J.4    Moss, B.5    Pastan, I.6    Berger, E.A.7
  • 8
    • 0028922605 scopus 로고
    • Design of a genetic immunotoxin to eliminate toxin immunogenicity
    • Chen, S.-Y., Zani, C., Khouri, Y. and Marasco, W.A. (1995) Design of a genetic immunotoxin to eliminate toxin immunogenicity. Gene Ther. 2, 116-123.
    • (1995) Gene Ther. , vol.2 , pp. 116-123
    • Chen, S.-Y.1    Zani, C.2    Khouri, Y.3    Marasco, W.A.4
  • 9
    • 2442723342 scopus 로고    scopus 로고
    • Treatment of HIV infection with Saquinavir, Zidovudine, and Zalcitabine
    • Collier, A.C., Coombs, R.W., Schoenfeld, D.A. et al. (1996) Treatment of HIV infection with Saquinavir, Zidovudine, and Zalcitabine. New Engl. J. Med. 334, 1011-1017.
    • (1996) New Engl. J. Med. , vol.334 , pp. 1011-1017
    • Collier, A.C.1    Coombs, R.W.2    Schoenfeld, D.A.3
  • 10
    • 0028135433 scopus 로고
    • Recombinant soluble CD4-pseudomonas exotoxin, a novel immunotoxin, in the treatment of individuals infected with HIV
    • Davey, R.T., Boenning, C.M., Herpin, B.R. et al. (1994) Recombinant soluble CD4-pseudomonas exotoxin, a novel immunotoxin, in the treatment of individuals infected with HIV. J. Inf. Dis. 170, 1180-1188.
    • (1994) J. Inf. Dis. , vol.170 , pp. 1180-1188
    • Davey, R.T.1    Boenning, C.M.2    Herpin, B.R.3
  • 11
    • 0028822171 scopus 로고
    • Processing of the envelope glycoprotein gp160 in immunotoxin-resistant cell lines chronically infected with HIV-1
    • Duensing, T.D., Fang, H., Dorward, D.W. and Pincus, S.H. (1995) Processing of the envelope glycoprotein gp160 in immunotoxin-resistant cell lines chronically infected with HIV-1. J. Virol. 69, 7122-7131.
    • (1995) J. Virol. , vol.69 , pp. 7122-7131
    • Duensing, T.D.1    Fang, H.2    Dorward, D.W.3    Pincus, S.H.4
  • 12
    • 0028924782 scopus 로고
    • Unique insertion sequence and pattern of CD4 expression in variants selected with immunotoxins from human immunodeficiency virus type 1-infected T cells
    • Fang, H. and Pincus, S.H. (1995) Unique insertion sequence and pattern of CD4 expression in variants selected with immunotoxins from human immunodeficiency virus type 1-infected T cells. J. Virol. 69, 75-81.
    • (1995) J. Virol. , vol.69 , pp. 75-81
    • Fang, H.1    Pincus, S.H.2
  • 13
    • 0025834347 scopus 로고
    • Selective elimination of HIV-1-infected cells with an interleukin-2 receptor-specific cytotoxin
    • Finberg, R.W., Wahl, S.M., Allen, J.B. et al. (1991) Selective elimination of HIV-1-infected cells with an interleukin-2 receptor-specific cytotoxin. Science 252, 1703-1705.
    • (1991) Science , vol.252 , pp. 1703-1705
    • Finberg, R.W.1    Wahl, S.M.2    Allen, J.B.3
  • 15
    • 0011958288 scopus 로고
    • Phase I/II evaluation of DAB-IL2 in HIV infection
    • Ives, D.V., Schaad, H., Hirschhorn, L. et al. (1994) Phase I/II evaluation of DAB-IL2 in HIV Infection. Abstracts ICAAC 34, 126.
    • (1994) Abstracts ICAAC , vol.34 , pp. 126
    • Ives, D.V.1    Schaad, H.2    Hirschhorn, L.3
  • 16
    • 0027208577 scopus 로고
    • Radioimmunotherapy of B-cell lymphoma with 131-I anti-B1 (anti-CD20) antibody
    • Kaminski, M.S., Zasadny, K.R., Francis, I.R. et al. (1993) Radioimmunotherapy of B-cell lymphoma with 131-I anti-B1 (anti-CD20) antibody. N. Engl. J. Med. 329, 459-465.
    • (1993) N. Engl. J. Med. , vol.329 , pp. 459-465
    • Kaminski, M.S.1    Zasadny, K.R.2    Francis, I.R.3
  • 17
    • 0027306775 scopus 로고
    • Primary HIV-1 refractory to neutralization by soluble CD4 are potently inhibited by CD4-Pseudomonas exotoxin
    • Kennedy, P.E., Moss, B. and Berger, E.A. (1993) Primary HIV-1 refractory to neutralization by soluble CD4 are potently inhibited by CD4-Pseudomonas exotoxin. Virology 192, 375-379.
    • (1993) Virology , vol.192 , pp. 375-379
    • Kennedy, P.E.1    Moss, B.2    Berger, E.A.3
  • 18
    • 0025944070 scopus 로고
    • Phase I trial of H65-RTA immunoconjugate in patients with cutaneous T-cell lymphoma
    • LeMaistre, C. F., Rosen, S., Frankel, A. et al. (1991) Phase I trial of H65-RTA immunoconjugate in patients with cutaneous T-cell lymphoma. Blood 78, 1173-1182.
    • (1991) Blood , vol.78 , pp. 1173-1182
    • LeMaistre, C.F.1    Rosen, S.2    Frankel, A.3
  • 19
    • 0027378573 scopus 로고
    • A conserved neutralizing epitope on gp41 of human immunodeficiency virus type 1
    • Muster, T., Steindl, F., Purtscher, M. et al. (1993) A conserved neutralizing epitope on gp41 of human immunodeficiency virus type 1. J. Virol. 67, 6642-6647.
    • (1993) J. Virol. , vol.67 , pp. 6642-6647
    • Muster, T.1    Steindl, F.2    Purtscher, M.3
  • 20
    • 0024574345 scopus 로고
    • Treatment of HIV tissue culture infection with monoclonal antibody-ricin a chain conjugates
    • Pincus, S.H., Wehrly, K. and Chesebro, B. (1989) Treatment of HIV tissue culture infection with monoclonal antibody-ricin A chain conjugates. J. Immunol. 142, 3070-3075.
    • (1989) J. Immunol. , vol.142 , pp. 3070-3075
    • Pincus, S.H.1    Wehrly, K.2    Chesebro, B.3
  • 21
    • 0025252496 scopus 로고
    • AZT demonstrates anti-HIV-1 activity in persistently infected cell lines: Implications for combination chemotherapy and immunotherapy
    • Pincus, S.H. and Wehrly, K. (1990) AZT demonstrates anti-HIV-1 activity in persistently infected cell lines: implications for combination chemotherapy and immunotherapy. J. Infect. Dis. 162, 1233-1238.
    • (1990) J. Infect. Dis. , vol.162 , pp. 1233-1238
    • Pincus, S.H.1    Wehrly, K.2
  • 22
    • 0025160549 scopus 로고
    • Variants selected by treatment of human immunodeficiency virus-infected cells with an immunotoxin
    • Pincus, S.H., Wehrly, K., Tschachler, E., Hayes, S.F., Buller, R.S. and Reitz, M. (1990) Variants selected by treatment of human immunodeficiency virus-infected cells with an immunotoxin. J. Exp. Med. 172, 745-757.
    • (1990) J. Exp. Med. , vol.172 , pp. 745-757
    • Pincus, S.H.1    Wehrly, K.2    Tschachler, E.3    Hayes, S.F.4    Buller, R.S.5    Reitz, M.6
  • 23
    • 0026050483 scopus 로고
    • In vitro efficacy of anti-HIV immunotoxins targeted by various antibodies to the envelope protein
    • Pincus, S.H., Cole, R.L., Hersh, E.M., Lake, D., Masuho, Y., Durda, P.J. and McClure, J. (1991) In vitro efficacy of anti-HIV immunotoxins targeted by various antibodies to the envelope protein. J. Immunol. 146, 4315-4324.
    • (1991) J. Immunol. , vol.146 , pp. 4315-4324
    • Pincus, S.H.1    Cole, R.L.2    Hersh, E.M.3    Lake, D.4    Masuho, Y.5    Durda, P.J.6    McClure, J.7
  • 24
    • 0027473587 scopus 로고
    • Soluble CD4 enhances the efficacy of immunotoxins directed against gp41 of the human immunodeficiency virus
    • Pincus, S.H. and McClure, J. (1993) Soluble CD4 enhances the efficacy of immunotoxins directed against gp41 of the human immunodeficiency virus. Proc. Natl. Acad. Sci. USA 90, 332-336.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 332-336
    • Pincus, S.H.1    McClure, J.2
  • 25
    • 0028090285 scopus 로고
    • Anti-HIV immunotoxins: gp41 rather than gp120 should be the target
    • Pincus, S.H. (1994) Anti-HIV immunotoxins: gp41 rather than gp120 should be the target. Int. Antiviral News 2, 147-148.
    • (1994) Int. Antiviral News , vol.2 , pp. 147-148
    • Pincus, S.H.1
  • 26
    • 0028197244 scopus 로고
    • Use of anti-HIV immunotoxins as probes of the biology of HIV-infected cells
    • Pincus, S.H., McClure, J. and Fang, H. (1994) Use of anti-HIV immunotoxins as probes of the biology of HIV-infected cells. Can. J. Infect. Dis. 5(suppl. A), 23A-27A.
    • (1994) Can. J. Infect. Dis. , vol.5 , Issue.SUPPL. A
    • Pincus, S.H.1    McClure, J.2    Fang, H.3
  • 27
    • 0029190901 scopus 로고
    • Anti-human immunodeficiency virus immunoconjugates
    • Pincus, S.H. and Tolstikov, V.V. (1995) Anti-human immunodeficiency virus immunoconjugates. Adv. Pharmacol. 32, 205-242.
    • (1995) Adv. Pharmacol. , vol.32 , pp. 205-242
    • Pincus, S.H.1    Tolstikov, V.V.2
  • 28
    • 0029776743 scopus 로고    scopus 로고
    • In vitro effects of anti-HIV immunotoxins directed against multiple epitopes on the HIV-1 envelope glycoprotein gp160
    • Pincus, S.H., Wehrly, K., Cole, R. et al. (1996) In vitro effects of anti-HIV immunotoxins directed against multiple epitopes on the HIV-1 envelope glycoprotein gp160. AIDS Res. Hum. Retro viruses, 12, 1041-1051.
    • (1996) AIDS Res. Hum. Retro Viruses , vol.12 , pp. 1041-1051
    • Pincus, S.H.1    Wehrly, K.2    Cole, R.3
  • 29
    • 0027484445 scopus 로고
    • Radio-labeled-antibody therapy of B-cell lymphoma with autologous bone marrow support
    • Press, O.W., Eary, J.F., Appelbaum, F.R. et al. (1993) Radio-labeled-antibody therapy of B-cell lymphoma with autologous bone marrow support. N. Engl. J. Med. 329, 1219-1224.
    • (1993) N. Engl. J. Med. , vol.329 , pp. 1219-1224
    • Press, O.W.1    Eary, J.F.2    Appelbaum, F.R.3
  • 30
    • 0027965596 scopus 로고
    • Failure of short-term CD4-PE40 infusions to reduce viral load in HIV infected individuals
    • Ramachandran, R.V., Katzenstein, D.A., Wood, R., Batts, D.H. and Merigan, T.C. (1994) Failure of short-term CD4-PE40 infusions to reduce viral load in HIV infected individuals. J. Infect. Dis. 170, 1009-1013.
    • (1994) J. Infect. Dis. , vol.170 , pp. 1009-1013
    • Ramachandran, R.V.1    Katzenstein, D.A.2    Wood, R.3    Batts, D.H.4    Merigan, T.C.5
  • 32
    • 0025131849 scopus 로고
    • Inhibition of expression of human immunodeficiency virus-1 in vitro by antibody-targeted liposomes containing antisense RNA to the env region
    • Renneisen, K., Leserman, L., Matthes, E., Schroder, H.C. and Muller, W.E. (1990) Inhibition of expression of human immunodeficiency virus-1 in vitro by antibody-targeted liposomes containing antisense RNA to the env region. J. Biol. Chem. 265, 16337-16342.
    • (1990) J. Biol. Chem. , vol.265 , pp. 16337-16342
    • Renneisen, K.1    Leserman, L.2    Matthes, E.3    Schroder, H.C.4    Muller, W.E.5
  • 33
    • 0011983709 scopus 로고
    • MAB labelled liposomes as vehicles for AZT: Choice of specific monoclonal antibodies for infected cells
    • Amsterdam, The Netherlands
    • Rombi, G., Piu, G., Piro, S., Pautasso, M., Garau, G. and Palomba, A. (1992). MAB labelled liposomes as vehicles for AZT: choice of specific monoclonal antibodies for infected cells. VIII Int. Conf. AIDS, Amsterdam, The Netherlands.
    • (1992) VIII Int. Conf. AIDS
    • Rombi, G.1    Piu, G.2    Piro, S.3    Pautasso, M.4    Garau, G.5    Palomba, A.6
  • 34
    • 0027299097 scopus 로고
    • Effects of administration of an anti-CD5 plus immunoconjugate in rheumatoid arthritis: Results of two phase two studies
    • Strand, V., Lipsky, P.E., Cannon, G.W. et al. (1993) Effects of administration of an anti-CD5 plus immunoconjugate in rheumatoid arthritis: results of two phase two studies. Arthritis Rheum. 36, 620-630.
    • (1993) Arthritis Rheum. , vol.36 , pp. 620-630
    • Strand, V.1    Lipsky, P.E.2    Cannon, G.W.3
  • 36
    • 3042652257 scopus 로고
    • Human immunodeficiency virus-infected T cells and monocytes are killed by monoclonal human anti-gp41 antibodies coupled to ricin A chain
    • Till, M.A., Zolla-Pazner, S., Gorny, M.K., Patton, J.S., Uhr, J.W. and Vitetta, E.S. (1989) Human immunodeficiency virus-infected T cells and monocytes are killed by monoclonal human anti-gp41 antibodies coupled to ricin A chain. Proc. Natl. Acad. Sci. USA 86, 1987-1991.
    • (1989) Proc. Natl. Acad. Sci. USA , vol.86 , pp. 1987-1991
    • Till, M.A.1    Zolla-Pazner, S.2    Gorny, M.K.3    Patton, J.S.4    Uhr, J.W.5    Vitetta, E.S.6
  • 37
    • 0025119720 scopus 로고
    • CD4-Pseudomonas exotoxin conjugates delay but do not fully inhibit human immunodeficiency virus replication in lymphocytes in vitro
    • Tsubota, H., Winkler, G., Meade, H.M., Jakubowski, A., Thomas, D.W. and Letvin, N.L. (1990) CD4-Pseudomonas exotoxin conjugates delay but do not fully inhibit human immunodeficiency virus replication in lymphocytes in vitro. J. Clin. Invest. 86, 1684-1689.
    • (1990) J. Clin. Invest. , vol.86 , pp. 1684-1689
    • Tsubota, H.1    Winkler, G.2    Meade, H.M.3    Jakubowski, A.4    Thomas, D.W.5    Letvin, N.L.6
  • 38
    • 0027438088 scopus 로고
    • Continuous presence of CD4-PE40 is required for antiviral activity against single passage HIV isolates and infected peripheral blood mononuclear cells
    • Winters, M.A. and Merigan, T.C. (1993) Continuous presence of CD4-PE40 is required for antiviral activity against single passage HIV isolates and infected peripheral blood mononuclear cells. AIDS Res. Hum. Retroviruses 9, 1091-1096.
    • (1993) AIDS Res. Hum. Retroviruses , vol.9 , pp. 1091-1096
    • Winters, M.A.1    Merigan, T.C.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.