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Volumn 21, Issue 4, 1996, Pages 277-288

Towards a vaccine candidate against Shigella dysenteriae 1: Expression of the Shiga toxin B-subunit in an attenuated Shigella flexneri aroD carrier strain

Author keywords

Shiga toxin; Shigella dysenteriae 1; shigellosis; vaccine

Indexed keywords

POLYCLONAL ANTIBODY; SHIGA TOXIN; SHIGELLA VACCINE;

EID: 0030272907     PISSN: 08824010     EISSN: None     Source Type: Journal    
DOI: 10.1006/mpat.1996.0061     Document Type: Article
Times cited : (21)

References (42)
  • 2
    • 0026092278 scopus 로고
    • Shigellosis in Vietnam: Seroepidemiological studies with use of lipopolysaccharide antigens in enzyme immunoassays
    • 2. Lindberg AA, Cam PD, Chan N, Phu LK, Trach DD, Lindberg G. Shigellosis in Vietnam: seroepidemiological studies with use of lipopolysaccharide antigens in enzyme immunoassays. Rev Infect Dis 1991; 13(Suppl. 4): 231-7.
    • (1991) Rev Infect Dis , vol.13 , Issue.SUPPL. 4 , pp. 231-237
    • Lindberg, A.A.1    Cam, P.D.2    Chan, N.3    Phu, L.K.4    Trach, D.D.5    Lindberg, G.6
  • 5
    • 0011990313 scopus 로고
    • Preparation, characterization and immunogenicity of conjugates composed of the O-specific polysaccharide of Shigella dysenteriae type 1 (Shiga's bacillus) bound to tetanus toxoid
    • 5. Chu C-Y, Liu B, Watson D, Szu SC, Bryla K, Shiloach J, Schneerson R, Robbins JB. Preparation, characterization and immunogenicity of conjugates composed of the O-specific polysaccharide of Shigella dysenteriae type 1 (Shiga's bacillus) bound to tetanus toxoid. Infect Immun 1992; 40: 245-56.
    • (1992) Infect Immun , vol.40 , pp. 245-256
    • Chu, C.-Y.1    Liu, B.2    Watson, D.3    Szu, S.C.4    Bryla, K.5    Shiloach, J.6    Schneerson, R.7    Robbins, J.B.8
  • 6
    • 0028152329 scopus 로고
    • Immune responses in Vietnamese children after a single dose of the auxotrophic, live Shigella flexneri Y vaccine strain SFL124
    • 6. Li A, Cam PD, Islam D, Minh NB, Huan PT, Rong ZC, Karlsson K, Lindberg G, Lindberg AA. Immune responses in Vietnamese children after a single dose of the auxotrophic, live Shigella flexneri Y vaccine strain SFL124. J Infection 1994; 28: 11-23.
    • (1994) J Infection , vol.28 , pp. 11-23
    • Li, A.1    Cam, P.D.2    Islam, D.3    Minh, N.B.4    Huan, P.T.5    Rong, Z.C.6    Karlsson, K.7    Lindberg, G.8    Lindberg, A.A.9
  • 8
    • 0023854742 scopus 로고
    • Site of action of a Vero toxin(VT2) from Escherichia coli O157:H7 and of Shiga toxin on eukaryotic ribosomes. RNA N-glycosidase activity of the toxins
    • 8. Endo Y, Tsurugi K, Yutsudo T, Takeda T, Ogasawara T, Igarashi K. Site of action of a Vero toxin(VT2) from Escherichia coli O157:H7 and of Shiga toxin on eukaryotic ribosomes. RNA N-glycosidase activity of the toxins. Eur J Biochem 1988; 171: 45-50.
    • (1988) Eur J Biochem , vol.171 , pp. 45-50
    • Endo, Y.1    Tsurugi, K.2    Yutsudo, T.3    Takeda, T.4    Ogasawara, T.5    Igarashi, K.6
  • 10
    • 0024370025 scopus 로고
    • Inoculum size in shigellosis and implications for expected mode of transmission
    • 10. DuPont HL, Levine MM, Hornick RB, Formal SB. Inoculum size in shigellosis and implications for expected mode of transmission. J Infect Dis 1989; 159: 1126-8.
    • (1989) J Infect Dis , vol.159 , pp. 1126-1128
    • DuPont, H.L.1    Levine, M.M.2    Hornick, R.B.3    Formal, S.B.4
  • 11
    • 0020660978 scopus 로고
    • Shigella dysenteriae 1 cytotoxin: Periplasmic protein releasable by polymyxin B and osmotic shock
    • 11. Donohue-Rolfe A, Keusch GT. Shigella dysenteriae 1 cytotoxin: periplasmic protein releasable by polymyxin B and osmotic shock. Infect Immun 1983; 39: 270-4.
    • (1983) Infect Immun , vol.39 , pp. 270-274
    • Donohue-Rolfe, A.1    Keusch, G.T.2
  • 12
    • 0024362998 scopus 로고
    • Expression of Shiga toxin epitopes in E. coli, immunological characterization
    • 12. McEwen J, Leitner M, Harrari I,Arnon R. Expression of Shiga toxin epitopes in E. coli, immunological characterization. Immunol Lett 1989; 21: 157-63.
    • (1989) Immunol Lett , vol.21 , pp. 157-163
    • McEwen, J.1    Leitner, M.2    Harrari, I.3    Arnon, R.4
  • 13
    • 0026028189 scopus 로고
    • An auxotrophic live oral Shigella flexneri vaccine: Development and testing
    • 13. Kärnell A, Stocker BAD. An auxotrophic live oral Shigella flexneri vaccine: development and testing. Rev Infect Dis 1991; 13(Suppl 4): 357-61.
    • (1991) Rev Infect Dis , vol.13 , Issue.SUPPL. 4 , pp. 357-361
    • Kärnell, A.1    Stocker, B.A.D.2
  • 14
    • 0026596654 scopus 로고
    • Live oral auxotrophic Shigella flexneri SFL124 vaccine with a deleted aroD gene: Characterisation and monkey protection studies
    • 14. Kärnell A, Stocker BAD, Katakura S, Reinholt FP, Lindberg AA. Live oral auxotrophic Shigella flexneri SFL124 vaccine with a deleted aroD gene: characterisation and monkey protection studies. Vaccine 1991; 10:389-94.
    • (1991) Vaccine , vol.10 , pp. 389-394
    • Kärnell, A.1    Stocker, B.A.D.2    Katakura, S.3    Reinholt, F.P.4    Lindberg, A.A.5
  • 16
    • 0027024897 scopus 로고
    • Extracellular export of Shiga toxin-subunit/haemolysin A (C-terminus) fusion protein expressed in Salmonella typhimurium aroA-mutant and stimulation of B-subunit specific antibody responses in mice
    • 16. Su G-F, Brahmbhatt HN, de Lorenzo V, Wehland J, Timmis KN. Extracellular export of Shiga toxin-subunit/haemolysin A (C-terminus) fusion protein expressed in Salmonella typhimurium aroA-mutant and stimulation of B-subunit specific antibody responses in mice. Microb Pathogen 1992; 13: 465-76.
    • (1992) Microb Pathogen , vol.13 , pp. 465-476
    • Su, G.-F.1    Brahmbhatt, H.N.2    De Lorenzo, V.3    Wehland, J.4    Timmis, K.N.5
  • 17
    • 9044241320 scopus 로고
    • Haemolsyin secretion and other protein translocation mechanisms in gram-negative bacteria
    • Baumberg S, Hinster I, Rhodes M, eds. Cambridge: Cambridge University Press
    • 17. Holland IB, Wang R, Seror SJ, Blight M. Haemolsyin secretion and other protein translocation mechanisms in gram-negative bacteria, In: Baumberg S, Hinster I, Rhodes M, eds. Microbial Products, New Approaches. Cambridge: Cambridge University Press, 1990: 219-54.
    • (1990) Microbial Products, New Approaches , pp. 219-254
    • Holland, I.B.1    Wang, R.2    Seror, S.J.3    Blight, M.4
  • 18
  • 19
    • 0025047590 scopus 로고
    • Transposon vectors containing non-antibiotic resistance selection markers for cloning and stable chromosomal insertion of foreign genes in Gram-negative bacteria
    • 19. Herrero M, de Lorenzo V, Timmis KN. Transposon vectors containing non-antibiotic resistance selection markers for cloning and stable chromosomal insertion of foreign genes in Gram-negative bacteria. J Bacteriol 1990; 172: 6557-67.
    • (1990) J Bacteriol , vol.172 , pp. 6557-6567
    • Herrero, M.1    De Lorenzo, V.2    Timmis, K.N.3
  • 20
    • 0024605613 scopus 로고
    • r and the IncII Plasmid pHH1508a
    • r and the IncII Plasmid pHH1508a. J Bacteriol 1989; 171: 2160-5.
    • (1989) J Bacteriol , vol.171 , pp. 2160-2165
    • Walter, E.1    Taylor, D.2
  • 21
    • 0023178639 scopus 로고
    • Development of vaccines against shigellosis: Memorandum from a WHO meeting
    • 21. World Health Organization. Development of vaccines against shigellosis: memorandum from a WHO meeting. Bull WHO 1987; 65: 17-25.
    • (1987) Bull WHO , vol.65 , pp. 17-25
  • 23
    • 0026525072 scopus 로고
    • Safety and immunogenicity of the live oral auxotrophic Shigella flexneri SFL124 in volunteers
    • 23. Li A, Pál T, Forsun U, Lindberg, AA. Safety and immunogenicity of the live oral auxotrophic Shigella flexneri SFL124 in volunteers. Vaccine 1992; 10: 395-404.
    • (1992) Vaccine , vol.10 , pp. 395-404
    • Li, A.1    Pál, T.2    Forsun, U.3    Lindberg, A.A.4
  • 24
    • 0000632797 scopus 로고
    • TnphoA: A transposon probe for protein export signals
    • 24. Manoil C, Beckwith J. TnphoA: a transposon probe for protein export signals. Proc Natl Acad Sci USA 1985; 82: 8129-33.
    • (1985) Proc Natl Acad Sci USA , vol.82 , pp. 8129-8133
    • Manoil, C.1    Beckwith, J.2
  • 25
    • 0021027842 scopus 로고
    • A broad host range mobilization system for in vivo genetic engineering: Transposon mutagenesis in Gram negative bacteria
    • 25. Simon R, Priefer U, Pühler A. A broad host range mobilization system for in vivo genetic engineering: transposon mutagenesis in Gram negative bacteria. Bio/Technology 1983; 1:784-91.
    • (1983) Bio/Technology , vol.1 , pp. 784-791
    • Simon, R.1    Priefer, U.2    Pühler, A.3
  • 26
    • 0021943518 scopus 로고
    • Improved M13 phage cloning vectors and host strains: Nucleotide sequences of the M13mp18 and pUC19 vectors
    • 26. Yanisch-Perron C, Vieira J, Messing J. Improved M13 phage cloning vectors and host strains: nucleotide sequences of the M13mp18 and pUC19 vectors. Gene 1985; 33: 103-19.
    • (1985) Gene , vol.33 , pp. 103-119
    • Yanisch-Perron, C.1    Vieira, J.2    Messing, J.3
  • 28
    • 0023892552 scopus 로고
    • A novel suicide vector and its use in construction of insertion mutations: Osmoregulation of outer membrane proteins and virulence determinants in Vibrio cholerae requires toxR
    • 28. Miller VL, Mekalanos JJ. A novel suicide vector and its use in construction of insertion mutations: osmoregulation of outer membrane proteins and virulence determinants in Vibrio cholerae requires toxR. J Bacteriol 1988; 170: 2575-83.
    • (1988) J Bacteriol , vol.170 , pp. 2575-2583
    • Miller, V.L.1    Mekalanos, J.J.2
  • 29
    • 0023571657 scopus 로고
    • High-copy number and low-copy number plasmid vectors for lacZα-complementation and chloramphenicol-or kanamycin-resistant selection
    • 29. Takeshita S, Sato M, Toba M, Masahashi W, Hashimoto-Gotoh T. High-copy number and low-copy number plasmid vectors for lacZα-complementation and chloramphenicol-or kanamycin-resistant selection. Gene 1987; 61: 63-74.
    • (1987) Gene , vol.61 , pp. 63-74
    • Takeshita, S.1    Sato, M.2    Toba, M.3    Masahashi, W.4    Hashimoto-Gotoh, T.5
  • 30
    • 0022260426 scopus 로고
    • Nucleotide sequence of an Escherichia coli chromosomal hemolysin
    • 30. Felmlee T, Pellett S, Welsh RA. Nucleotide sequence of an Escherichia coli chromosomal hemolysin. J Bacteriol 1985; 163: 94-105.
    • (1985) J Bacteriol , vol.163 , pp. 94-105
    • Felmlee, T.1    Pellett, S.2    Welsh, R.A.3
  • 31
    • 0022800438 scopus 로고
    • The carboxy-terminal region of haemolysin 2001 is required for secretion of the toxin from Escherichia coli
    • 31. Gray L, Mackman N, Nicaud J-M, Holland IB. The carboxy-terminal region of haemolysin 2001 is required for secretion of the toxin from Escherichia coli. Mol Gen Genet 1986; 205: 127-33.
    • (1986) Mol Gen Genet , vol.205 , pp. 127-133
    • Gray, L.1    Mackman, N.2    Nicaud, J.-M.3    Holland, I.B.4
  • 32
    • 0020959710 scopus 로고
    • Studies in transformation of Escherichia coli with plasmids
    • 32. Hanahan D. Studies in transformation of Escherichia coli with plasmids. J Mol Biol 1983; 166: 577-80.
    • (1983) J Mol Biol , vol.166 , pp. 577-580
    • Hanahan, D.1
  • 33
    • 0024988821 scopus 로고
    • High efficiency transformation of Salmonella typhimurium and Salmonella typhi by electroporation
    • 33. O'Callaghan D, Charbit A. High efficiency transformation of Salmonella typhimurium and Salmonella typhi by electroporation. Mol Gen Genet 1990; 223: 156-8.
    • (1990) Mol Gen Genet , vol.223 , pp. 156-158
    • O'Callaghan, D.1    Charbit, A.2
  • 34
    • 0014949207 scopus 로고
    • Cleavage of structural proteins during assembly of the heads of bacteriophage T4
    • 34. Laemmli UK. Cleavage of structural proteins during assembly of the heads of bacteriophage T4. Nature 1970; 227: 680-5.
    • (1970) Nature , vol.227 , pp. 680-685
    • Laemmli, U.K.1
  • 35
    • 0009482260 scopus 로고
    • Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: Procedure and some applications
    • 35. Towbin H, Staehlin H, Gordon G. Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. Proc Natl Acad Sci USA 1979; 76: 4350-4.
    • (1979) Proc Natl Acad Sci USA , vol.76 , pp. 4350-4354
    • Towbin, H.1    Staehlin, H.2    Gordon, G.3
  • 37
    • 0020536197 scopus 로고
    • Morphological heterogeneity among Salmonella lipopolysaccharide chemotypes in silver stained polyacrylamide gels
    • 37. Hitchcock PJ, Brown TM. Morphological heterogeneity among Salmonella lipopolysaccharide chemotypes in silver stained polyacrylamide gels. J Bacteriol 1983; 154: 269-77.
    • (1983) J Bacteriol , vol.154 , pp. 269-277
    • Hitchcock, P.J.1    Brown, T.M.2
  • 38
    • 0029164354 scopus 로고
    • Expression of Shigella dysenteriae serotype 1 O-antigenic polysaccharide by Shigella flexneri aroD vaccine candidates and different S. flexneri serotypes
    • 38. Fält IC, Sweda EKH, Klee S, Singh M, Floderus E, Timmis KN, Lindberg AA. Expression of Shigella dysenteriae serotype 1 O-antigenic polysaccharide by Shigella flexneri aroD vaccine candidates and different S. flexneri serotypes. J Bacteriol 1995; 177: 5310-5.
    • (1995) J Bacteriol , vol.177 , pp. 5310-5315
    • Fält, I.C.1    Sweda, E.K.H.2    Klee, S.3    Singh, M.4    Floderus, E.5    Timmis, K.N.6    Lindberg, A.A.7
  • 39
    • 0011918219 scopus 로고
    • Rapid procedure for detection and isolation of large and small plasmids
    • 39. Kado Cl, Liu ST. Rapid procedure for detection and isolation of large and small plasmids. J Clin Microbiol 1981; 30: 2801-6.
    • (1981) J Clin Microbiol , vol.30 , pp. 2801-2806
    • Kado, Cl.1    Liu, S.T.2
  • 40
    • 0024256088 scopus 로고
    • An assay for growth of mouse bone marrow cells in microtiter liquid culture using the terazolium salt MTT, and its application to studies of myelopoiesis
    • 40. Monner DA. An assay for growth of mouse bone marrow cells in microtiter liquid culture using the terazolium salt MTT, and its application to studies of myelopoiesis. Immunol Lett 1988; 19: 261-8.
    • (1988) Immunol Lett , vol.19 , pp. 261-268
    • Monner, D.A.1
  • 41
    • 0023001581 scopus 로고
    • The C-terminal, 23 kDa peptide of E. coli haemolysin 2001 contains all the information necessary for its secretion by the haemolysin (Hly) export machinery
    • 41. Nicaud JM, Mackman M, Gray L, Holland IB. The C-terminal, 23 kDa peptide of E. coli haemolysin 2001 contains all the information necessary for its secretion by the haemolysin (Hly) export machinery. FEBS Letters 1986; 204: 331-5.
    • (1986) FEBS Letters , vol.204 , pp. 331-335
    • Nicaud, J.M.1    Mackman, M.2    Gray, L.3    Holland, I.B.4
  • 42
    • 0022350984 scopus 로고
    • Genetical and functional organisation of the Escherichia coli haemolysin determinants 2001
    • 42. Mackman N, Nicaud J-M, Gray L, Holland IB. Genetical and functional organisation of the Escherichia coli haemolysin determinants 2001. Mol Gen Genet 1985; 201: 282-8.
    • (1985) Mol Gen Genet , vol.201 , pp. 282-288
    • Mackman, N.1    Nicaud, J.-M.2    Gray, L.3    Holland, I.B.4


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