Repression of thrombospondin-1 expression, a natural inhibitor of angiogenesis, in polyoma middle T transformed NIH3T3 cells

Cancer Letters

Volumn 107, Issue 1, 1996, Pages 45-52

  Sheibani, Nader ^a   Frazier, William A ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Angiogenesis; Middle T; Signal transduction; Thrombospondins; Transformation

Indexed keywords

GLYCOPROTEIN; MESSENGER RNA; THROMBOSPONDIN; VIRUS MIDDLE T ANTIGEN;

ANGIOGENESIS; ANIMAL CELL; ARTICLE; CELL INVASION; CELL STRAIN 3T3; EXTRACELLULAR MATRIX; GENE REPRESSION; METASTASIS; MOUSE; NONHUMAN; ONCOGENE C JUN; PHENOTYPE; POLYOMA VIRUS; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; VIRUS CELL TRANSFORMATION;

ANIMALIA; POLYOMAVIRUS;

EID: 0030272798     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/0304-3835(96)04341-8     Document Type: Article

References (27)

1. [1] Adams, J. and Lawler, J. (1993) The thrombospondin family, Curr. Biol., 3, 188-190.
2. [2] Bornstein, P., Devarayalu, S., Li, P., Disteche, C.M. and Framson, P. (1991) A second thrombospondin gene in the mouse is similar in organization to thrombospondin 1 but does not respond to serum, Proc. Natl. Acad. Sci. USA, 88, 8636-8640.
3. [3] Bornstein, P. and Sage, E.H. (1994) Thrombospondins, Methods Enzymol., 245, 62-85.
4. [4] Brizuela, L., Olcese, L.M. and Courtneidge, S.A. (1994) Transformation by middle T antigens, Semin. Virol., 5, 381-389.
5. [5] Dameron, K.M., Volpert, O.V., Tainsky, M.A. and Bouck, N.P. (1994) Control of angiogenesis in fibroblasts by p53 regulation of thrombospondin-1, Science, 225, 1582-1584.
6. [6] Dilworth, S.M., Brewster, C.E.P., Jones, M.D., Lanfrancone, L., Pelicci, G. and Pilicci, P.G. (1994) Transformation by polyoma virus middle T-antigen involves the binding and tyrosine phosphorylation of Shc, Nature, 367, 87-90.
7. [7] Frazier, W.A. (1991) Thrombospondins, Curr. Opin. Cell. Biol., 3, 792-799.
8. [8] Hu, E., Mueller, E., Oliviero, S., Papaioannou, V.E., Johnson, R. and Spiegelman, B.M. (1994) Targeted disruption of the c-fos gene demonstrates c-fos-dependent and -independent pathways for gene expression stimulated by growth factors or oncogenes, EMBO J., 13, 3094-3103.
9. [9] Iruela-Arispe, M.L., Liska, D.J., Sage, E.H. and Bornstein, P. (1993) Differential expression of thrombospondin 1,2, and 3 during murine development, Dev. Dynam., 197, 40-56.
10. [10] Kiefer, F., Anhauser, I., Soriano, P., Aguzzi, A., Courtneidge, S.A. and Wagner, E.F. (1994) Endothelial cell transformation by polyomavirus middle T antigen in mice lacking Src-related kinases, Curr. Biol., 4, 100-109.
11. [11] Matrisian, L.M., Leroy, P., Ruhlmann, C., Gesnel, M.C. and Breathnach, R. (1986) Isolation of the oncogene and epidermal growth factor-induced transin gene: complex control in rat fibroblasts, Mol. Cell. Biol., 6, 1679-1686.
12. [12] Mettouchi, A., Cabon, F., Montreau, N., Vernier, P., Mercier, G., Blangy, D., Tricoire, H., Vigier, P. and Binetruy, B. (1994) SPARC and thrombospondin genes are repressed by the c-jun oncogene in rat embryo fibroblasts, EMBO J., 13, 5668-5678.
13. [13] Raptis, L., Marcellus, R., Corbley, M.J., Krook, A., Whitfield, J., Anderson, S.K. and Haliotis, T. (1991) Cellular ras gene activity is required for full neoplastic transformation by polyomavirus, J. Virol., 65, 5203-5210.
14. [14] Salnikow, K., Cosentino, S., Klein, C. and Costa, M. (1994) Loss of thrombospondin transcriptional activity in nickel-transformed cells, Mol. Cell. Biol., 14, 851-858.
15. [15] Schutte, J., Minna, J.J. and Birrer, M. (1989) Deregulated expression of human c-jun transforms primary rat embryo cells in cooperation with an activated c-Ha-ras gene and transforms rat-la cells as a single gene, Proc. Natl. Acad. Sci. USA, 86, 2257-2261.
16. [16] Sheibani, N. and Frazier, W.A. (1995) Thrombospondin 1 expression in transformed endothelial cells restores a normal phenotype and suppresses their tumorigenesis, Proc. Natl. Acad. Sci. USA, 92, 6788-6792.
17. [17] Slack, J.L. and Bornstein, P. (1994) Transformation by v-src causes transient induction followed by repression of mouse thrombospondin-1, Cell Growth Diff., 5, 1373-1380.
18. [18] Srinivas, S., Schonthal, A. and Eckhart, W. (1994) Polyomavirus middle-sized tumor antigen modulates c-Jun phosphorylation and transcriptional activity, Proc. Natl. Acad. Sci. USA, 91, 10064-10068.
19. [19] Talmage, D.A. and Listerud, M. (1994) Retinoic acid suppresses polyoma virus transformation by inhibiting transcription of the c-fos proto-oncogene, Oncogene, 9, 3557-3563.
20. [20] Thomas, J.E., Aguzzi, A., Soriano, P., Wagner, E.F. and Brugge, J.S. (1993) Induction of tumor formation and cell transformation by polyoma middle T antigen in the absence of Src, Oncogene, 8, 2521-2529.
21. [21] Tolsma, S.S., Volpert, O.V., Good, D.J., Frazier, W.A., Polverini, P.J. and Bouck, N. (1993) Peptides derived from two separate domains of the matrix protein thrombospondin-1 have anti-angiogenic activity, J. Cell Biol., 122, 497-511.
22. [22] Treisman, R., Novak, U., Favaloro, J. and Kamen, R. (1981) Transformation of rat cells by an altered polyoma virus genome expressing only the middle-T protein, Nature, 292, 595-600.
23. [23] Volpert, O.V., Tolsma, S.S., Pellerin, S., Feige, J.J., Chen, H., Mosher, D.F. and Bouck, N. (1995) Inhibition of angiogenesis by thrombospondin-2, Biochem. Biophys. Res. Commun., 217, 326-332.
24. [24] Weinstat-Saslow, D.L., Zabrenetzky, V.S., VanHoutte, K., Frazier, W.A., Roberts, D.D. and Steeg, P.S. (1994) Transfection of thrombospondin 1 complementary DNA into a human breast carcinoma cell line reduces primary tumor growth, metastatic potential, and angiogenesis, Cancer Res., 54, 6504-6511.
25. [25] Westermarck, J., Lohi, J., Keski-Oja, J. and Kahari, V.M. (1994) Okadaic acid-elicited transcriptional activation of collagenase gene expression in HT-1080 fibrosarcoma cells is mediated by junB, Cell Growth Diff., 5, 1205-1213.
26. [26] Williams, R.L., Courtneidge, S.A. and Wagner, E.F. (1988) Embryonic lethalities and endothelial tumors in chimeric mice expressing polyoma virus middle T oncogene, Cell, 52, 121-131.
27. [27] Zabrenetzky, V., Harris, C.C., Steeg, P.S. and Roberts, D.D. (1994) Expression of the extracellular matrix molecule thrombospondin inversely correlates with malignant progression in melanoma, lung and breast carcinoma cell lines, Int. J. Cancer, 59, 191-195.