Expression of Fas antigen and Fas ligand in the rheumatoid synovial tissue

Clinical Immunology and Immunopathology

Volumn 81, Issue 1, 1996, Pages 27-34

  Asahara, Hiroshi ^a,c   Hasumuna, Tomoko ^a   Kobata, Tetsuji ^a   Yagita, Hideo ^b   Okumura, Ko ^b   Inoue, Hajime ^c   Gay, Steffen ^d   Sumida, Takayuki ^a   Nishioka, Kusuki ^a  

^a ST MARIANNA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b JUNTENDO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c OKAYAMA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^d UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FAS ANTIGEN;

ADULT; AGED; APOPTOSIS; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MALE; NATURAL KILLER CELL; OSTEOARTHRITIS; PRIORITY JOURNAL; RHEUMATOID ARTHRITIS; SYNOVIOCYTE; T LYMPHOCYTE SUBPOPULATION;

EID: 0030272623     PISSN: 00901229     EISSN: None     Source Type: Journal    
DOI: 10.1006/clin.1996.0153     Document Type: Article

References (35)

1. 1. Gay, S., Gay, R. E., and Koopman, W. J., Molecular and cellular mechanisms of joint destruction in rheumatoid arthritis: Two cellular mechanisms explain joint destruction? Ann. Rheum. Dis. 52, 39-47, 1993.
2. 2. Yamamoto, K., Sakoda, H., Nakajima, T., Kato, T., Okubo, M., Dohi, M., Mizushima, Y., Ito, K., and Nishioka, K., Accumulation of multiple T cell clonotypes in the synovial lesions of patients with rheumatoid arthritis revealed by a novel clonality analysis. Int. Immunol. 4, 1219-1223, 1992.
3. 3. Ikeda, Y., Masuko, K., Nakai, Y., Kato, T., Hasunuma, T., Yoshino, S., Mizushima, Y., Nishioka, K., and Yamamoto, K., High frequencies of identical T cell clonotypes in synovial tissues of rheumatoid arthritis patients suggest the occurrence of common antigen-driven immune responses. Arthritis Rheum., in press.
4. 4. Goto, M., and Zvaifler, N. J., Characterization of the natural killer-like lymphocytes in rheumatoid synovial fluid. J. Immunol. 134, 1483-1486, 1985.
5. 5. Goto, M., Miyamoto, T., Nishioka, K., and Uchida, S., T cytotoxic and helper cells are markedly increased, and T suppresser and inducer cells are markedly decreased in rheumatoid synovial fluids. Arthritis Rheum. 30, 737-743, 1987.
6. 6. Young, L. H., Joag, S. V., Lin, P. Y., Luo, S. F., Zheng, L. M., Liu, C. C., and Young, J. D., Expression of cytolytic mediators by synovial fluid lymphocytes in rheumatoid arthritis. Am. J. Pathol. 140, 1261-1268, 1992.
7. 7. Griffiths, G. M., Alpert, S., Lambert, E., McGuire, J., and Weissman, I. L., Perforin and granzyme A expression identifying cytolytic lymphocytes in rheumatoid arthritis. Proc. Natl. Acad. Sci. USA. 89, 549-553, 1992.
8. 8. Kummer, J. A., Tak, P. P., Brinkman, B., Van Tilborg, A. A. G., Kamp, A. M., Daha, M. R., Meinders, A. E., Hack, C. E., and Breedveld, F. C., Expression of granzymes A and B in synovial tissue from patients with rheumatoid arthritis and osteoarthritis. Clin. Immunol. Immunopathol. 73, 88-95, 1994.
9. 9. Müller-Ladner, U., Kriegsmann, J., Tschopp, J., Gay, R. E., and Gay, S., Demonstration of granzyme A and perforin messenger RNA in the synovium of patients with rheumatoid arthritis. Arthritis Rheum. 38, 477-484, 1995.
10. 10. Tak, P. P., Kummer, J. A., Hack, C. E., Daha, M. R., Smeets, T. J. M., Erkelens, G. W., Meinders, A. E., Kluin, P. M., and Breedveld, F. C., Granzyme-positive cytotoxic cells are specifically increased in early rheumatoid synovial tissue. Arthritis Rheum. 37, 1735-1743, 1994.
11. 11. Kägi, D., Vagnaux, F., Ledermann, B., Bürki, K., Deraetere, V., Nagata, S., Hengartner, H., and Golstein, P., Fas and perform pathway as major mechanisms of T cell-mediated cytotoxicity. Science 265, 528-530, 1994.
12. 12. Takahashi, T., Tanaka, M., Brannan, C. I., Jenkins, N. A., Copeland, N. G., Suda, T., and Nagata, S., Generalized lymphoproliferative disease in mice, caused by a point mutation in the Fas ligand. Cell 76, 969-976, 1994.
13. 13. Watanabe-Fukunaga, R., Brannan, C. I., Copeland, N. G., Jenkins, N. A., and Nagata, S., Lymphoproliferation disorder in mice explained by defects in Fas antigen that mediates apoptosis. Nature 356, 314-317, 1992.
14. 14. Adachi, M., Watanabe-Fukunaga, R., and Nagata, S., Aberrant transcription caused by the insertion of an early transposable element in an intron of the Fas antigen gene of lpr mice. Proc. Natl. Acad. Sci. USA 90, 1756-1765, 1993.
15. 15. Nakajima, T., Aono, H., Hasunuma, T., Yamamoto, K., Shirai, T., Hirohata, K., and Nishioka, K., Apoptosis and functional Fas antigen in rheumatoid arthritis synoviocyte. Arthritis Rheum. 38, 485-491, 1995.
16. 16. Firestein, G. S., Yeo, M., and Zvaifler, N. J., Apoptosis in rheumatoid arthritis synovium. J. Clin. Invest. 96, 1631-1638, 1995.
17. 17. Arnett, F. C., Edworthy, S. M., and Bloch, D. A., The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis. Arthritis Rheum. 31, 315-324, 1988.
18. 18. Kayagaki, N., Kawasaki, A., Ebata, T., Ohmoto, H., Ikeda, S., Inoue, S., Yoshino, K., Okumura, K., and Yagita, H., Metalloproteinase-mediated release of human Fas ligand. J. Exp. Med. 182, 1777-1784, 1995.
19. 19. Gavrich, Y., Sherman, Y., and Ben-Sasson, S. A., Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation. J. Cell. Biol. 119, 493-501, 1992.
20. 20. Goto, M., Sasano, M., Yamanaka, H., Miyasaka, N., Kamatani, N., Inoue, K., Nishioka, K., and Miyamoto, T., Spontaneous production of an interleukin-1-like factor by cloned rheumatoid synovial cells. J. Clin. Invest. 80, 786-796, 1987.
21. 21. Kinoshita, T., Imamura, J., Nagai, H., and Shimotohno, K., Quantification of gene expression over a wide range by the polymerase chain reaction. Anal. Biochem. 206, 231-235, 1992.
22. 22. Lanzillo, J. J., Chemiluminescent nucleic acid detection with digoxigenin-labeled probes: A model system with robes for angiotensin converting enzyme which detect less than one attomole of target DNA. Anal. Biochem. 194, 45-53, 1991.
23. 23. Berke, G., The CTL's kiss of death. Cell 81, 9-12, 1995.
24. 24. Suda, T., Okazaki, T., Naito, Y., Yokota, T., Arai, N., Ozaki, S., Nakao, K., and Nagata, S., Expression of the Fas ligand in cells of T cell lineage. J. Immunol. 154, 3806-3813, 1995.
25. 25. Apasov, S., Redegeld, F., and Sitkovsky, M., Cell-mediated cytotoxicity: Contact and secreted factors. Curr. Opin. Immunol. 5, 404-410, 1993.
26. 26. Stalder, T., Hahn, S., and Erb, P., Fas antigen is the major target molecule for CD4+ T cell-mediated cytotoxicity. J. Immunol. 152, 1127-1133, 1994.
27. 27. Hanabuchi, S., Koyanagi, M., Kawasaki, A., Shinohara, N., Matuzawa, A., Nishimura, Y., Kobayashi, Y., Yonehara, S., Yagita, H., and Okumura, K., Fas and its ligand in a general mechanism of T cell mediated cytotoxicity. Proc. Natl. Acad. Sci. USA 91, 4930-4934, 1994.
28. 28. Fisher, G. H., Rosenberg, F. J., Straus, S. E., Middelton, L. A., Lin, A. Y., Strober, W., Lenardo, M. J., and Puck, J. M., Dominant interfering Fas gene mutations impair apoptosis in a human autoimmune lymphoproliferative syndrome. Cell 81, 935-946, 1995.
29. 29. Carson, D. A., and Ribeiro, J. M., Apoptosis and disease. Lancet 341, 1251-1254, 1993.
30. 30. Bursch, W., Lauer, B., Timmermann-Trosiener, I., Barthel, G., Schuppler, J., and Schulte-Hermann, R., Controlled death (apoptosis) of normal and putative preneoplastic cells in rat liver following withdrawal of tumor promoters. Carcinogenesis 5, 453-458, 1984.
31. 31. Columbano, A., Ledda-Clumbano, G. M., Rao, P. M., Rajalakshmi, S., and Sarma, D. S., Occurrence of cell death (apoptosis) in preneoplastic liver cells. Am. J. Pathol. 116, 441-446, 1984.
32. 32. Iwakura, Y., Tosu, M., Yoshida, E., Takiguchi, M., Sato, K., Kitajima, I., Nishioka, K., Yamamoto, K., Takeda, T., Hatanaka, M., Yamamoto, H., and Sekiguchi, T., Introduction of inflammatory arthropathy resembling rheumatoid arthritis in mice transgenic for HTLV-1. Science 253, 1026-1028, 1991.
33. 33. Fujisawa, K., Asahara, H., Okamoto, K., Aono, H., Hasunuma, T., Kobata, T., Iwakura, Y., Yonehara, S., Sumida, T., and Nishioka, K., Therapeutic effect of the anti-Fas antibody on arthritis in HTLV-1 tax transgenic mice. J. Clin. Invest., 98, 271-278, 1996.
34. 34. Hoa, T. T. M., Hasunuma, T., Aono, H., Masuko, K., Kobata, T., Yamamoto, K., Sumida, T., and Nishioka, K., Novel mechanisms of selective apoptosis in synovial T cells of patients with rheumatoid arthritis. J. Rheum., 23, 1332-1337, 1996.
35. 35. Hasunuma, T., Hoa, T. T. M., Aono, H., Asahara, H., Yonehara, S., Yamamoto, K., Sumida, T., Gay, S., and Nishioka, K., Induction of Fas-dependent apoptosis in synovial infiltrating cells in rheumatoid arthritis. Int. Immunol., in press.