The effects of discrete cingulum bundle lesions in the rat on the acquisition and performance of two tests of spatial working memory

Behavioural Brain Research

Volumn 80, Issue 1-2, 1996, Pages 75-85

  Neave, N ^a,c   Nagle, S ^a   Sahgal, A ^b   Aggleton, J P ^a,d  

^a DURHAM UNIVERSITY   (United Kingdom)

^b NEWCASTLE GENERAL HOSPITAL   (United Kingdom)

^c NORTHUMBRIA UNIVERSITY   (United Kingdom)

^d CARDIFF UNIVERSITY   (United Kingdom)

Author keywords

cingulate cortex; cingulum bundle; delayed nonmatching to position; spatial alternation; spatial memory

Indexed keywords

ANIMAL EXPERIMENT; ARTICLE; BRAIN INJURY; CINGULATE GYRUS; CONTROLLED STUDY; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; SPATIAL MEMORY;

EID: 0030272356     PISSN: 01664328     EISSN: None     Source Type: Journal    
DOI: 10.1016/0166-4328(96)00022-8     Document Type: Article

References (26)

1. [1] Aggleton, J.P., Hunt, P.R., Nagle, S. and Neave, N., The effects of selective lesions within the anterior thalamic nuclei on spatial memory in the rat, Behav. Brain Res., in press.
2. [2] Aggleton, J.P., Hunt, P.R. and Rawlins, J.N.P., The effects of hippocampal lesions upon spatial and non-spatial tests of working memory, Behav. Brain Res., 19 (1986) 133-146.
3. [3] Aggleton, J.P., Keith, A.B. and Sahgal, A., Both fornix and anterior thalamic, but not mammillary, lesions disrupt delayed matching-to-position memory in rats, Behav. Brain Res., 44 (1991) 151-161.
4. [4] Aggleton, J.P., Neave, N., Nagle, S. and Hunt, P.R., A comparison of the effects of anterior thalamic, mammillary body and fornix lesions on reinforced spatial alternation, Behav. Brain Res., 68 (1995) 91-101.
5. [5] Aggleton, J.P., Neave, N., Nagle, S. and Sahgal, A., A comparison of the effects of medial prefrontal, cingulate cortex, and cingulum bundle lesions on tests of spatial memory: evidence of a double dissociation between frontal and cingulum bundle contributions, J. Neurosci., 15 (1995) 7270-7281.
6. [6] Blair, H.T. and Sharp, P.E., Anticipatory head direction signals in the anterior thalamus: evidence for a thalamocortical circuit that integrates angular head motion to compute head direction, J. Neurosci., 15 (1995) 6260-6270.
7. [7] Domesick, V.B., The fasciculus cinguli in the rat, Brain Res., 20 (1970) 19-32.
8. [8] Frey, P.W. and Colliver, J.A., Sensitivity and responsiveness measures for discrimination learning, Learn. Mot., 4 (1973): 327-342.
9. [9] Gutnikov, S.A., Barnes, J.C. and Rawlins, J.N.P., Working memory tasks in five-choice operant chambers: use of relative and absolute spatial memories, Behav. Neurosci., 108 (1994) 899-910.
10. [10] Markowska, A.L., Olton, D.S., Murray, E.A. and Gaffan, D., A comparative analysis of the role of fornix and cingulate cortex in memory: rats, Exp. Brain Res., 74 (1989) 187-201.
11. [11] Meunier, M. and Destrade, C., Electrolytic but not ibotenic lesions of the posterior cingulate cortex produce transitory facilitation of learning in mice, Behav. Brain Res., 27 (1988) 161-172.
12. [12] Mizumori, S.J.Y., Miya, D.Y. and Ward, K.E., Reversible inactivation of the lateral dorsal thalamus disrupts hippocampal place representation and impairs spatial learning, Brain Res., 644 (1994) 168-174.
13. [13] Morris, R.G.M., Garrud, P., Rawlins, J.N.P. and O'Keefe, J., Place navigation impaired in rats with hippocampal lesions, Nature, 297 (1982) 681-683.
14. [14] Mufson, E.J. and Pandya, D.N., Some observations on the course and composition of the cingulum bundle in the rhesus monkey, J. Comp. Neurol., 225 (1984) 31-43.
15. [15] Neave, N., Sahgal, A. and Aggleton, J.P., Lack of effect of dorsomedial thalamic lesions on automated tests of spatial memory in the rat, Behav. Brain Res., 55 (1993) 39-49.
16. [16] Neave, N., Lloyd, S., Sahgal, A. and Aggleton, J.P., Lack of effect of lesions in the anterior cingulate cortex and retrosplenial cortex on certain tests of spatial memory in the rat, Behav. Brain Res., 65 (1994) 89-101.
17. [17] O'Keefe, J. and Nadel, L., The Hippocampus as a Cognitive Map, Clarendon Press, Oxford, 1978.
18. [18] Pellegrino, L.J. and Cushman, A.J., Stereotaxic Atlas of the Rat Brain, Appleton-Century-Crofts, New York, 1967.
19. [19] Sahgal, A., Some limitations of indices derived from signal detec" tion theory: Evaluation of an alternative index for measuring bias in memory tasks, Psychopharmacology, 91 (1987) 517-520.
20. [20] Sutherland, R.J. and Hoesing, J.M., Posterior cingulate cortex and spatial memory: a microlimnology analysis. In B.A. Vogt and M. Gabriel (Eds.), Neurobiology of Cingulate Cortex and Limbic Thalamus: A Comprehensive Treatise, Birkhauser, Boston, 1993, pp. 461-477.
21. [21] Sutherland, R.J. and Rodriguez, A.J., The role of the fornix/fimbria and some related subcortical structures in place learning and memory, Behav. Brain Res., 32 (1989) 265-277.
22. [22] Sutherland, R.J., Whishaw, I.Q. and Kolb, B., Contributions of cingulate cortex to two forms of spatial learning and memory, J. Neurosci., 8 (1988) 1863-1872.
23. [23] Taube, J.S., Head detection cells recorded in the anterior thalamic nuclei of freely moving rats, J. Neurosci., 15 (1995) 70-86.
24. [24] Taube, J.S., Muller, R.U. and Ranck, J.B., Jr., Head-direction cells recorded from the postsubiculum in freely moving rats. I. Description and quantitative analysis, J. Neurosci., 10 (1990) 420-435.
25. [25] Van Groen, T. and Wyss, J.M., Projections from the anterodorsal and anteroventral nucleus of the thalamus to the limbic cortex in the rat, J. Comp. Neurol., 358 (1995) 584-604.
26. [26] Winer, B.J., Statistical Principles in Experimental Design, 2nd Ed., McGraw-Hill, Tokyo, 1971.