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85030274624
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note
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(19) Only in the case described in ref.3h a high value of e.e. for VIII (80%) is obtained.
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36
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0000770498
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(22) Currently, two different mechanisms for the osmylation are being considered: a concerted [3 + 2] cycloaddition mechanism and a stepwise mechanism which is, formally, the product of a [2 + 2] cycloaddition. Recent literature [see for instance, (a) Noorby, P.-O.; Kolb, H. C.; Sharpless, K. B. J. Am. Chem. Soc. 1994, 116, 8470-8478.
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0000041330
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4 can interact with an olefinic double bond in a situation very similar to that described by Corey in ref. 3c and solved by the [3 + 2] mechanism.
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42
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note
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26b and dried in vacuo. Activated copper bronze should be used immediately. All manipulations were carried out under nitrogen.
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44
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