Sex steroids, pregnancy-associated hormones and immunity to parasitic infection

Parasitology Today

Volumn 12, Issue 10, 1996, Pages 382-388

  Roberts, Craig W ^a,b   Satoskar, Abhay ^b   Alexander, James ^b  

^a MICHAEL REESE HOSPITAL   (United States)

^b UNIVERSITY OF STRATHCLYDE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ESTRADIOL; PROGESTERONE; SEX HORMONE; TESTOSTERONE;

ADULT; CHILD; FEMALE; FETUS; HOST RESISTANCE; HUMAN; IMMUNITY; INFANT; MALE; PARASITOSIS; PREGNANCY; REVIEW; SEX DIFFERENCE;

EID: 0030272068     PISSN: 01694758     EISSN: None     Source Type: Journal    
DOI: 10.1016/0169-4758(96)10060-0     Document Type: Review

References (56)

1. 1 Alexander, J. and Stimson, W.H. (1988) Sex hormones and the course of parasitic infection. Parasitol. Today 4, 189-193
2. 2 Brabin, L. and Brabin, B.J. (1992) Parasitic infections in women and their consequences. Adv. Parasitol. 31, 1-60
3. 3 Forest, M.G. (1990) in Control of the Onset of Puberty (Grunmbach, M.M., Sizonenko, P.C. and Aubert, M.L., eds), pp 451-477, Williams and Wilkins
4. 4 Tulchinsky, D. et al. (1972) Hormones in human pregnancy. IV Plasma progesterone. Am. J. Obstet. Gynecol. 112, 1095-1100
5. 5 Styrt, B. and Sugarman, B. (1991) Estrogens and infection. Rev. Infect. Dis. 13, 1139-1148
6. 6 Luft, B.J. and Remington, J.S. (1982) Effect of pregnancy on resistance to Listeria monocytogenes and Toxoplasma gondii infections in mice. Infect. Immun. 38, 1164-1171
7. 7 Shirahata, T. et al. (1993) Enhancement by recombinant human interleukin 2 of host resistance to Toxoplasma gondii infection in pregnant mice. Microbiol. Immunol. 37, 583-590
8. 8 Shirahata, T. et al. (1992) Correlation between increased susceptibility to primary Toxoplasma gondii infection and depressed production of gamma interferon in pregnant mice. Microbiol. Immunol. 36, 81-91
9. 9 Menendez, C. (1995) Malaria during pregnancy: a priority area of malaria research and control. Parasitol. Today 5, 178-183
10. 10 Benten, W.P., Wunderlich, F. and Mossmann, H. (1992) Testosterone-induced suppression of self healing Plasmodium chabaudi: an effect not mediated by androgen receptors? J. Endocrinol. 135, 407-413
11. 11 Benten, W.P., Wunderlich, F. and Mossmann, H. (1992) Plasmodium chabaudi: estradiol suppresses acquiring, but not once acquired immunity. Exp. Parasitol. 75, 240-247
12. 12 Lammie, P.J. et al. (1993) Heterogeneity in filarial-specific immune responsiveness among patients with lymphatic obstruction. J. Infect. Dis. 167, 1178-1783
13. 13 Larradale, C. et al. (1989) Sex hormone changes induced by the parasite lead to feminization of the male host in murine Taenia crassiceps cyticercosis. J. Steroid Biochem. Mol. Biol. 52, 575-580
14. 14 Tiuria, R. et al. (1994) The indian soft-furred rat, Millardia meltada, a new host for Nippostrongylus brasiliensis, showing androgen-dependent sex difference in intestinal mucosal defence. Internatl. J. Parasitol. 24, 1055-1057
15. 15 Terrazas, L.I. et al. (1994) A role for 17-beta-estradiol in immunoendocrine regulation of cysticercosis. J. Parasitol. 80, 563-568
16. 16 Henry, L. and Beverley, J.K.A. (1976) Age and sex differences in the response of lymph node post-capillary venules in mice infected with Toxoplasma gondii. J. Exp. Pathol. 57, 274-281
17. 17 Kittas, C. and Henry, L. (1979) Effect of gonadectomy and oestrogen administration on the response of lymph-node post-capillary venules to infection with Toxoplasma gondii. J. Pathol. 127, 129-136
18. 18 Kittas, C. and Henry, L. (1980) Effect of sex hormones on the response of mice to infection with Toxoplasma gondii. Br. J. Exp. Pathol. 61, 590-600
19. 19 Kittas, C. and Henry, L. (1984) A histological and immunohistochemical study of the changes induced in the brains of white mice by infection with Toxoplasma gondii. Br. J. Exp. Pathol. 65, 67-74
20. 20 Kittas, C. and Henry, L. (1979) Effect of sex hormones on the immune system of guinea-pigs and on the development of toxoplasmic lesions in non-lymphoid organs. Clin. Exp. Immunol. 36, 16-23
21. 21 Gazzinelli, R.T. et al. (1993) Host resistance to Toxoplasma gondii: Model for studying the selective induction of cell-mediated immunity by intracellular parasites. Infect. Agents Dis. 2, 139-149
22. 22 Hunter, C.A., Subauste, C.S. and Remington, J.S. (1994) The role of cytokines in toxoplasmosis. Biotherapy 7, 237-247
23. 23 Hunter, C.A. et al. (1995) Transforming growth factor-beta inhibits interleukin-12-induced production of interferon-gamma by natural killer cells: a role for transforming growth factor-beta in the regulation of T-cell-independent resistance to Toxoplasma gondii. Eur. J. Immunol. 25, 994-1000
24. 24 Langermans, J.A.M. et al. (1992) IFN-γ-induced L-arginine-dependent toxoplasmastatic activity in murine peitoneal macrophages is mediated by endogenous tumor necrosis factor-α. J. Immunol. 148, 568-574
25. 25 Chao, T.C. et al. (1994) Steroid sex hormones and macrophage function: modulation of reactive oxygen intermediates and nitrate release. Am. J. Reprod. Immunol. 32, 43-52
26. 26 Roberts, C.W., Cruickshank, S.M. and Alexander, J. (1995) Sex-determined resistance to Toxoplasma gondii is associated with temporal differences in cytokine production. Infect. Immun. 63, 2549-2555
27. + T cells in mice. J. Immunol. 140, 3943-3946
28. + T cells are the major lymphocyte subpopulation involved in the protective immune response to Toxoplasma gondii in mice. Clin. Exp. Immunol. 84, 207-212
29. 29 Cohen, J.H.M. et al. (1983) Sex steroids receptors in peripheral T cells: absence of androgen receptors and restriction of estrogen receptors to OKT8-positive cells. J. Immunol. 131, 2767-2771
30. 30 Cosma, J. (1973) in Thymic Hormones (Turck, T.D., ed.), pp 59-89, University Park Press
31. 31 Fox, H.S., Bond, B.L. and Parslow, T.G. (1991) Estrogen regulates the IFN-gamma promoter. J. Immunol. 146, 4362-4367
32. 32 Piccinni, M-P. et al. (1995) Progesterone favors the development of human T helper cells producing Th2-type cytokines and promotes both IL-4 production and membrane CD30 expression in established Th1 cell clones. J. Immunol. 155, 128-133
33. 33 Beverley, J.K.A. et al. (1976) Age-sex distribution of various diseases with particular reference to toxoplasmic lymph-adenopathy. J. Hyg. 76, 215-228
34. 34 Phillips, A.N. et al. (1994) A sex comparison of rates of new AIDS-defining disease and death in 2554 AIDS cases. AIDS 8, 831-835
35. 35 Satoskar, A. and Alexander, J. (1995) Sex-determined susceptibility and differential IFN-gamma and TNF-alpha mRNA expression in DBA/2 mice infected with Leishmania mexicana. Immunology 84, 1-4
36. 36 Lynch, N., et al. (1982) Delayed-type hypersensitivity and immunoglobulin E in American cutaneous leishmaniasis. Infect. Immun. 38, 877-888
37. 37 Akingbade, O.A. (1992) Embryotoxic and growth retarding effects of malaria on pregnant mice. J. Reprod. Med. 37, 273-276
38. 38 Rasheed, F.N. et al. (1993) Suppressed peripheral and placental blood lymphoproliferative response in first pregnancies: relevance to malaria. Am. J. Trop. Med. Hyg. 48, 154-160
39. 39 Mvondo, J.L. and James, M.A. (1992) Malaria and pregnancy in Cameroonian women. Effect of pregnancy on Plasmodium falciparum parasitaemia and response to chloroquine. Trop. Med. Parasitol. 43, 1-5
40. 40 Gabrilovac, J. et al. (1988) NK cell activity and estrogen levels during normal human pregnancy. Gynecol. Obstet. Invest. 25, 165-172
41. 41 Sorachi, K.L. et al. (1993) Enhancing effect of 17 beta-estradiol on human NK cell activity. Immunol. Lett. 1, 31-36
42. 42 Nilsson, N. and Carlstein, H. (1994) Estrogen induces suppression of natural killer cell cytotoxicity and augmentation of polyclonal B cell activation. Cell. Immunol. 158, 131-139
43. 43 Polan, M.L. et al. (1989) Progesterone and estradiol modulate interleukin-1 beta messenger ribonucleic acid levels in cultured human peripheral monocytes. J. Clin. Endocrinol. Metab. 89, 1200-1206
44. 44 Wang, Y., Campbell, H.D. and Young, I.G. (1993) Sex hormones and dexamethasone modulate interleukin-5 gene expression in T-lymphocytes. J. Steroid Biochem. Mol. Biol. 44, 203-210
45. 45 Ahmed, A.S., Dauphinee, M.J. and Talal, N. (1985) Effects of short-term administration of sex hormones on normal and autoimmune mice. J. Immunol. 134, 204-210
46. 46 Ralston, S.H., Russell, R.G.G. and Gowen, M. (1990) Estrogen inhibits release of tumor necrosis factor from peripheral blood mononuclear cells in post menopausal women. J. Bone Mineral Res. 5, 983-988
47. 47 Szekeres-Bartho, J. (1989) Progesterone-treated lymphocytes of healthy pregnant women release a factor inhibiting cytotoxicity and prostoglandin synthesis. Cell. Immunol. 122, 281-294
48. 48 Hu, S.K., Mitchuo, Y.L. and Rath, A.C. (1988) Effect of estradiol on interleukin 1 synthesis by macrophages. Int. J. Immunopharmacol. 10, 247-252
49. 49 Grasso, G. and Muscettola, M. (1990) The influence of beta estradiol and progesterone on interferon gamma production in vitro. Int. J. Neurosci. 51, 315-317
50. 50 Kuhnle, G. et al. (1994) Androgen binding sites in peripheral human mononuclearleukocytes of healthy males and females. J. Steroid Biochem. Mol. Biol. 48, 403-408
51. 51 Araneo, B.A. et al. (1991) Dihydrotestosterone exerts a depressive influence on the production of interleukin-4 (IL-4), IL-5, and gamma-interferon, but not IL-2 by activated murine T cells. Blood 78, 688-699
52. 52 Clark, D.A. (1991) Controversies in reproductive immunology. Clin. Rev. Immunol. 11, 215-247
53. 53 Lin, H. et al. (1993) Synthesis of T helper 2-Type cytokines at the maternal-fetal interface. J. Immunol. 151, 4562-4573
54. 54 Gendron, R.L. (1990) Lipopolysaccharide-induced fetal resorption in mice is associated with the intrauterine production of tumour necrosis factor-alpha. J. Reprod. Fertil. 90, 395-402
55. 55 Krishnan, L. et al. (1996) Pregnancy impairs resistance of C57BL/6 mice to Leishmania major infection and causes decreased antigen-specific IFN-γ responses and increased production of T helper 2 cytokines. J. Immunol. 156, 644-652
56. 56 Krishnan, L. et al. (1996) T helper 1 response against Leishmania major in pregnant C57BL/6 mice increases implantation failure and fetal resorptions. J. Immunol. 156, 653-662