Topological studies of the membrane component of the OleC ABC transporter involved in oleandomycin resistance in Streptomyces antibioticus

FEMS Microbiology Letters

Volumn 143, Issue 2-3, 1996, Pages 133-139

  Olano, Carlos ^a   Rodriguez, Ana Maria ^a   Méndez, Carmen ^a   Salas, José A ^a  

^a DEPARTAMENTO DE BIOQUÍMICA Y BIOLOGÍA MOLECULAR   (Spain)

Author keywords

Macrolide; Membrane protein; Polyketide; Recombinant DNA; Secondary metabolism

Indexed keywords

ABC TRANSPORTER; AMPICILLIN; BETA LACTAMASE; HYBRID PROTEIN; MEMBRANE PROTEIN; OLEANDOMYCIN;

ANTIBIOTIC RESISTANCE; ARTICLE; DNA SEQUENCE; ESCHERICHIA COLI; GENE DELETION; GENE FUSION; HYDROPHOBICITY; MINIMUM INHIBITORY CONCENTRATION; MODEL; MOLECULAR CLONING; NONHUMAN; PENICILLIN RESISTANCE; PLASMID; PRIORITY JOURNAL; PROTEIN LOCALIZATION; STREPTOMYCES ANTIBIOTICUS;

ESCHERICHIA COLI; STREPTOMYCES ANTIBIOTICUS;

EID: 0030271978     PISSN: 03781097     EISSN: None     Source Type: Journal    
DOI: 10.1016/0378-1097(96)00327-8     Document Type: Article

References (18)

1. [1] Higgins, C.F. (1992) ABC transporters: from microorganisms to man. Annu. Rev. Cell. Biochem. 8, 67-113.
2. [2] Guilfoile, P.G. and Hutchinson, C.R. (1991) A bacterial analog of the mdr gene of mammalian tumor cells is present in Streptomyces peucetius, the producer of daunorubicin and doxorubicin. Proc. Natl. Acad. Sci. USA 88, 8553-8557.
3. [3] Rosteck, P.R., Reynolds, P.A. and Hersberger, C.L. (1991) Homology between proteins controlling Streptomyces fradiae resistance and ATP-binding transport. Gene 102, 27-32.
4. [4] Rodriguez, A.M., Olano, C., Vilches, C., Méndez, C. and Salas, J.A. (1993) Streptomyces antibioticus contains at least three oleandomycin resistance determinants, one of which shows similarity with proteins of the ABC transporter superfamily. Mol. Microbiol. 8, 571-582.
5. [5] Linton, K.J., Cooper, H.N., Hunter, I.S. and Leadlay, P.F (1994) An ABC-transporter from Streptomyces longisporoflavus confers resistance to the polyether-ionophore antibiotic tetronasin. Mol. Microbiol. 11, 777-785.
6. [6] Olano, C., Rodriguez, A.M., Méndez, C. and Salas, J.A. (1995) A second ABC transporter is involved in oleandomycin resistance and its secretion by Streptomyces antibioticus. Mol. Microbiol. 16, 333-343.
7. [7] Fernández, E., Lombó, F., Méndez, C. and Salas, J.A. (1996) An ABC transporter is essential for resistance to the antitumor agent mithramycin in the producer Streptomyces argillaceus. Mol. Gen. Genet. (in press).
8. [8] Broome-Smith, J. and Spratt, B.G. (1986) A vector for the construction of translational fusions to EMB β-lactamase and the analysis of protein export signals and membrane protein topology. Gene 49, 341-349.
9. [9] Janssen, G.S. and Bibb, M.J. (1993) Derivatives of pUC18 that have Bg/II sites flanking a modified multiple cloning site and that retain the ability to identify recombinant clones by visual screening of Escherichia coli colonies. Gene 124, 133-134.
10. [10] Sambrook, J., Fritsch, E.F. and Maniatis, T. (1989) Molecular Cloning. A Laboratory Manual. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
11. [11] Hopwood, D.A., Bibb, M.J., Chater, K.F., Kieser, T., Bruton, C.J., Kieser, H.M., Lydiate, D.J., Smith. C.P., Ward, J.M. and Schrempf, H. (1985) Genetic Manipulation of Streptomyces: A Laboratory Manual. John Innes Institute, Norwich.
12. [12] Sanger, F., Nicklen, S. and Coulson, A.R. (1977) DNA sequencing with chain terminating inhibitors. Proc. Natl. Acad. Sci. USA 74, 5463-5467.
13. [13] Kyte, J. and Doolittle, R.F. (1982) A simple method for displaying the hydropathic character of a protein. J. Mol. Biol. 157, 105-132.
14. [14] Broome-Smith, J., Tadayyon, M. and Spratt, B.G. (1990) β-Lactamase as a probe of membrane protein assembly and protein export. Mol. Microbiol. 4, 1637-1644.
15. [15] Anderson, H., Bakker, E. and Heijne, G.V. (1992) Different positively charged amino acids have similar effects on the topology of a polytopic transmembrane protein in Escherichia coli. J. Biol. Chem. 267, 1491-1495.
16. [16] Pigeon, R.P. and Silver, R.P (1994) Topological and mutational analysis of KspM the hydrophobic component of the ABC-transporter in the export of polysialic acid in Escherichia coli Kl. Mol. Microbiol. 14, 871-891.
17. [17] Devereux, J., Haeberli, P. and Smithies, O. (1984) A comprehensive set of sequence analysis programs for the VAX. Nucleic Acids Res 12, 387-395.
18. [18] Eisenberg, D., Schwarz, E., Komaromy, M. and Wall, R. (1984) Analysis of membrane and surface protein sequences with the hydrophobic moment plot. J. Mol. Biol. 179, 125-142.