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Volumn 84, Issue 1, 1996, Pages 55-66

Effect of multimerization of human and recombinant von Willebrand factor on platelet aggregation, binding to collagen and binding of coagulation factor VIII

Author keywords

collagen binding; factor VIII; heparin; multimerization; recombinant von Willebrand factor; ristocetin cofactor activity

Indexed keywords

BLOOD CLOTTING FACTOR 8; COLLAGEN; HEPARIN; RECOMBINANT BLOOD CLOTTING FACTOR 8; RECOMBINANT VON WILLEBRAND FACTOR; UNCLASSIFIED DRUG; VON WILLEBRAND FACTOR;

EID: 0030271856     PISSN: 00493848     EISSN: None     Source Type: Journal    
DOI: 10.1016/0049-3848(96)00161-2     Document Type: Article
Times cited : (68)

References (52)
  • 1
    • 0026766155 scopus 로고
    • The structure and function of von Willebrand factor
    • 1. RUGGERI, Z.M. and WARE, J. The structure and function of von Willebrand factor. Thromb Haemost 67, 594-599, 1992.
    • (1992) Thromb Haemost , vol.67 , pp. 594-599
    • Ruggeri, Z.M.1    Ware, J.2
  • 2
    • 0019442145 scopus 로고
    • The complex multimeric composition of factor VIII/von Willebrand factor
    • 2. RUGGERI, Z.M. and ZIMMERMANN, T.S. The complex multimeric composition of factor VIII/von Willebrand factor. Blood 57, 1140-1143, 1981.
    • (1981) Blood , vol.57 , pp. 1140-1143
    • Ruggeri, Z.M.1    Zimmermann, T.S.2
  • 3
    • 0027536915 scopus 로고
    • Von Willebrand factor
    • 3. RUGGERI, Z.M. and WARE, J. Von Willebrand factor. FASEB J 7, 308-316, 1993.
    • (1993) FASEB J , vol.7 , pp. 308-316
    • Ruggeri, Z.M.1    Ware, J.2
  • 5
    • 0025916052 scopus 로고
    • The fine structure of von Willebrand factor multimers and type IIa von Willebrands disease
    • 5. LYNCH, D.C. The fine structure of von Willebrand factor multimers and type IIa von Willebrands disease. Ann NY Acad Sci 138, 138-152, 1993.
    • (1993) Ann NY Acad Sci , vol.138 , pp. 138-152
    • Lynch, D.C.1
  • 6
    • 0024470325 scopus 로고
    • Molecular cloning, expression and assembly of multimeric von Willebrand factor
    • 6. PANNEKOEK, H. and VOOREBERG, J. Molecular cloning, expression and assembly of multimeric von Willebrand factor. Bailliere's Clin Haematol 2, 879-896, 1989.
    • (1989) Bailliere's Clin Haematol , vol.2 , pp. 879-896
    • Pannekoek, H.1    Vooreberg, J.2
  • 7
  • 8
    • 0028314508 scopus 로고
    • Proteolysis of von Willebrand factor in therapeutic plasma concentrates
    • 8. MANNUCCI, P.M., LATTUADA, A. and RUGGERI, Z.M. Proteolysis of von Willebrand factor in therapeutic plasma concentrates. Blood 83, 3018-3027, 1994.
    • (1994) Blood , vol.83 , pp. 3018-3027
    • Mannucci, P.M.1    Lattuada, A.2    Ruggeri, Z.M.3
  • 9
    • 0018855952 scopus 로고
    • Variant von Willebrand disease
    • 9. RUGGERI, Z.M. and ZIMMERMAN, T.S. Variant von Willebrand disease. J Clin Invest 65, 1318-1325, 1980.
    • (1980) J Clin Invest , vol.65 , pp. 1318-1325
    • Ruggeri, Z.M.1    Zimmerman, T.S.2
  • 10
    • 0021350410 scopus 로고
    • Adhesion of platelets to human artery subendothelium: Effect of factor VIII-von Willebrand factor of various multimeric composition
    • 10. SIXMA, J.J., SAKARIASSEN, K.S., BEESER-VISSER, N.H., OTTENHOF-ROVERS, M. and BOLHUIS, P.A. Adhesion of platelets to human artery subendothelium: Effect of factor VIII-von Willebrand factor of various multimeric composition. Blood 63, 128-139, 1984.
    • (1984) Blood , vol.63 , pp. 128-139
    • Sixma, J.J.1    Sakariassen, K.S.2    Beeser-Visser, N.H.3    Ottenhof-Rovers, M.4    Bolhuis, P.A.5
  • 11
    • 0019442145 scopus 로고
    • The complex multimeric composition of factor VIII/von Willebrand factor
    • 11. RUGGERI, Z.M. and ZIMMERMAN, T.Z. The complex multimeric composition of factor VIII/von Willebrand factor. Blood 57, 1140-1143, 1981.
    • (1981) Blood , vol.57 , pp. 1140-1143
    • Ruggeri, Z.M.1    Zimmerman, T.Z.2
  • 12
    • 0019729424 scopus 로고
    • Classification of variant von Willebrand's disease subtypes by analysis of functional characteristics and multimeric composition of factor VIII/von Willebrand factor
    • 12. RUGGERI, Z.M. and ZIMMERMAN, T.S. Classification of variant von Willebrand's disease subtypes by analysis of functional characteristics and multimeric composition of factor VIII/von Willebrand factor. Ann New York Acad Sci 370, 205-209, 1981.
    • (1981) Ann New York Acad Sci , vol.370 , pp. 205-209
    • Ruggeri, Z.M.1    Zimmerman, T.S.2
  • 13
    • 0026073649 scopus 로고
    • Effects of deletion of the A1 domain of von Willebrand factor on its binding to heparin, collagen and platelets in the presence of ristocetin
    • 13. SIXMA, J.J., SCHIPHORST, M.E., VERWEIJ, C.L. and PANNEKOEK, H. Effects of deletion of the A1 domain of von Willebrand factor on its binding to heparin, collagen and platelets in the presence of ristocetin. Eur J Biochem 196, 369-375, 1991.
    • (1991) Eur J Biochem , vol.196 , pp. 369-375
    • Sixma, J.J.1    Schiphorst, M.E.2    Verweij, C.L.3    Pannekoek, H.4
  • 14
    • 0022649078 scopus 로고
    • Von Willebrand factor. A reduced and alkylated 52/48-kDa fragment beginning at amino acid residue 449 contains the domain interacting with platelet glycoprotein Ib
    • 14. FUJIMURA, Y., TITANI, K., HOLLAND, L.Z., RUSSELS, S.R., ROBERTS, J.R., EIDER, J.H., RUGGERI, Z.M. and ZIMMERMAN, T.S. Von Willebrand factor. A reduced and alkylated 52/48-kDa fragment beginning at amino acid residue 449 contains the domain interacting with platelet glycoprotein Ib. J Biol Chem 261, 381-385, 1986.
    • (1986) J Biol Chem , vol.261 , pp. 381-385
    • Fujimura, Y.1    Titani, K.2    Holland, L.Z.3    Russels, S.R.4    Roberts, J.R.5    Eider, J.H.6    Ruggeri, Z.M.7    Zimmerman, T.S.8
  • 15
    • 0024401499 scopus 로고
    • Isolation of the von Willebrand factor domain interacting with platelet glycoprotein Ib, heparin, and collagen and characterization of its three distinct functional sites
    • 15. MOHRI, H., YOSHIOKA, A., ZIMMERMAN, T.S. and RUGGERI, Z. Isolation of the von Willebrand factor domain interacting with platelet glycoprotein Ib, heparin, and collagen and characterization of its three distinct functional sites. J Biol Chem 264, 17361-17367, 1989.
    • (1989) J Biol Chem , vol.264 , pp. 17361-17367
    • Mohri, H.1    Yoshioka, A.2    Zimmerman, T.S.3    Ruggeri, Z.4
  • 16
    • 0024426748 scopus 로고
    • Production in Escherichia coli of a biologically active subfragment of von Willebrand factor corresponding to the platelet glycoprotein Ib, collagen and heparin binding domains
    • 16. PIETU, G., MEULIEN, P., CHEREL, G., DIAZ, J., BARUCH, D., COURTNEY, M. and MEYER, D. Production in Escherichia coli of a biologically active subfragment of von Willebrand factor corresponding to the platelet glycoprotein Ib, collagen and heparin binding domains. Biochem Biophys Res Com 164, 1339-1347, 1989.
    • (1989) Biochem Biophys Res Com , vol.164 , pp. 1339-1347
    • Pietu, G.1    Meulien, P.2    Cherel, G.3    Diaz, J.4    Baruch, D.5    Courtney, M.6    Meyer, D.7
  • 17
    • 0027427962 scopus 로고
    • The interaction of the von Willebrand factor A1 domain with platelet glycoprotein Ib/IX
    • 17. CRUZ, M.A., HANDIN, R.I. and WISE, R.J. The interaction of the von Willebrand factor A1 domain with platelet glycoprotein Ib/IX. J Biol Chem 268, 21238-21245, 1993.
    • (1993) J Biol Chem , vol.268 , pp. 21238-21245
    • Cruz, M.A.1    Handin, R.I.2    Wise, R.J.3
  • 18
    • 0027398579 scopus 로고
    • A role for von Willebrand factor proline residues 702-704 in ristocetin-mediated binding to platelet glycoprotein Ib
    • 18. AZUMA, H., SUGIMOTO, M., RUGGERI, Z.M. and WARE, J. A role for von Willebrand factor proline residues 702-704 in ristocetin-mediated binding to platelet glycoprotein Ib. Thromb Haemost 69, 192-196, 1993.
    • (1993) Thromb Haemost , vol.69 , pp. 192-196
    • Azuma, H.1    Sugimoto, M.2    Ruggeri, Z.M.3    Ware, J.4
  • 19
    • 0027314540 scopus 로고
    • Analysis of structure-function relationships in the platelet membran glycoprotein Ib-binding domain of von Willebrand's factor by expressing of deletion mutants
    • 19. SUGIMOTO, M., DENT, J., MCCLINTON, R., WARE, J. and RUGGERI, Z.M. Analysis of structure-function relationships in the platelet membran glycoprotein Ib-binding domain of von Willebrand's factor by expressing of deletion mutants. J Biol Chem 268, 12185-12192, 1993.
    • (1993) J Biol Chem , vol.268 , pp. 12185-12192
    • Sugimoto, M.1    Dent, J.2    Mcclinton, R.3    Ware, J.4    Ruggeri, Z.M.5
  • 20
    • 0027968340 scopus 로고
    • Structural analysis of recombinant von Willebrand factor: Identification of heteroand homo-dimers
    • 20. FISCHER, B., MITTERER, A., SCHLOKAT, U., DENBOUWMEESTER, R. and DORNER, F. Structural analysis of recombinant von Willebrand factor: identification of heteroand homo-dimers. FEBS Let. 351, 345-348, 1994.
    • (1994) FEBS Let. , vol.351 , pp. 345-348
    • Fischer, B.1    Mitterer, A.2    Schlokat, U.3    Denbouwmeester, R.4    Dorner, F.5
  • 21
    • 0028827115 scopus 로고
    • Structural analysis of recombinant von Willebrand factor produced at industrial scale fermentation of transformed CHO cells co-expressing recombinant furin
    • 21. FISCHER, B.E., SCHLOKAT, U., MITTERER, A., REITER, M., MUNDT, W., TURECEK, P.L., SCHWARZ, H.P. and DORNER, F. Structural analysis of recombinant von Willebrand factor produced at industrial scale fermentation of transformed CHO cells co-expressing recombinant furin. FEBS Lett 375, 259-262, 1995.
    • (1995) FEBS Lett , vol.375 , pp. 259-262
    • Fischer, B.E.1    Schlokat, U.2    Mitterer, A.3    Reiter, M.4    Mundt, W.5    Turecek, P.L.6    Schwarz, H.P.7    Dorner, F.8
  • 23
    • 0027293351 scopus 로고
    • Determination of rate and equilibrium binding constants for macromolecular interactions using surface plasmon resonance: Use of nonlinear least squares analysis methods
    • 23. O'SHANNESSY, D.J., BRINGHAM-BURKE, M., SONESON, K.K., HENSLEY, P. and BROOKS, I. Determination of rate and equilibrium binding constants for macromolecular interactions using surface plasmon resonance: use of nonlinear least squares analysis methods. Anal Biochem 212, 457-468, 1993.
    • (1993) Anal Biochem , vol.212 , pp. 457-468
    • O'Shannessy, D.J.1    Bringham-Burke, M.2    Soneson, K.K.3    Hensley, P.4    Brooks, I.5
  • 24
    • 0027978869 scopus 로고
    • Real-time competitive kinetic analysis of interactions between low-molecular-weight ligands in solution and surface-immobilized receptors
    • 24. KARLSSON, R. Real-time competitive kinetic analysis of interactions between low-molecular-weight ligands in solution and surface-immobilized receptors. Anal Biochem 221, 142-151, 1994.
    • (1994) Anal Biochem , vol.221 , pp. 142-151
    • Karlsson, R.1
  • 25
    • 0027916175 scopus 로고
    • Biospecific interaction analysis using biosensor technology
    • 25. MALMQVIST, M. Biospecific interaction analysis using biosensor technology. Nature 361, 186-187, 1993.
    • (1993) Nature , vol.361 , pp. 186-187
    • Malmqvist, M.1
  • 26
    • 0026806511 scopus 로고
    • Localization and characterization of a heparin binding domain peptide of human von Willebrand factor
    • 26. SOBEL, M., SOLER, D.F., KERMODE, J.C. and HARRIS, R.B. Localization and characterization of a heparin binding domain peptide of human von Willebrand factor. J Biol Chem 267, 8857-8862, 1992.
    • (1992) J Biol Chem , vol.267 , pp. 8857-8862
    • Sobel, M.1    Soler, D.F.2    Kermode, J.C.3    Harris, R.B.4
  • 27
    • 0027245385 scopus 로고
    • Heparin binding assay of von Willebrand factor (vWF) in plasma milieu - Evidence of the importance of the multimerization degree of vWF
    • 27. DE ROMEUF, C. and MAZURIER, C. Heparin binding assay of von Willebrand factor (vWF) in plasma milieu - Evidence of the importance of the multimerization degree of vWF. Thromb Haemost 69, 436-440, 1993.
    • (1993) Thromb Haemost , vol.69 , pp. 436-440
    • De Romeuf, C.1    Mazurier, C.2
  • 28
    • 0026149627 scopus 로고
    • Von Willebrand factor and platelet interactions with the vessel wall
    • 28. FRESSINAUD, E. and MEYER, D. Von Willebrand factor and platelet interactions with the vessel wall. Blood Coagul Fibrinolysis 2, 333-340, 1991.
    • (1991) Blood Coagul Fibrinolysis , vol.2 , pp. 333-340
    • Fressinaud, E.1    Meyer, D.2
  • 29
    • 0023547037 scopus 로고
    • Localization of a collagen-interactive domain of human von Willebrand factor between amino acid residue Gly 911 and Glu 1, 365
    • 29. KALIFATIS, M., TAKAHASHI, Y., GIRMA, J.-P. and MEYER, D. Localization of a collagen-interactive domain of human von Willebrand factor between amino acid residue Gly 911 and Glu 1, 365. Blood 70, 1577-1583, 1987.
    • (1987) Blood , vol.70 , pp. 1577-1583
    • Kalifatis, M.1    Takahashi, Y.2    Girma, J.-P.3    Meyer, D.4
  • 30
    • 0023230265 scopus 로고
    • Isolation and characterization of two domains of human von Willebrand factor that interact with fibrillar collagen types I and III
    • 30. PARETI, F.I., NIIYA, K., MCPERSON, J.M. and RUGGERI, Z.M. Isolation and characterization of two domains of human von Willebrand factor that interact with fibrillar collagen types I and III. J Biol Chem 262, 13835-13841, 1987.
    • (1987) J Biol Chem , vol.262 , pp. 13835-13841
    • Pareti, F.I.1    Niiya, K.2    Mcperson, J.M.3    Ruggeri, Z.M.4
  • 32
    • 0028914676 scopus 로고
    • Interaction of the von Willebrand factor (vWF) with collagen
    • 32. CRUZ, M. A., YUAN, H., LEE, J.R., WISE, R.J. and HANDIN, R.I. Interaction of the von Willebrand factor (vWF) with collagen. J Biol Chem 270, 10822-10827, 1995.
    • (1995) J Biol Chem , vol.270 , pp. 10822-10827
    • Cruz, M.A.1    Yuan, H.2    Lee, J.R.3    Wise, R.J.4    Handin, R.I.5
  • 33
    • 0026457996 scopus 로고
    • Characterization of recombinant von Willebrand factor corresponding to mutations in type IIA and type IIB von Willebrand disease
    • 33. RIBBA ,A.S., VOORBERG, J., MEYER, D., PANNEKOEK, H. and PIETO, G. Characterization of recombinant von Willebrand factor corresponding to mutations in type IIA and type IIB von Willebrand disease. J Biol Chem 267, 23209-2315, 1992.
    • (1992) J Biol Chem , vol.267 , pp. 23209-32315
    • Ribba, A.S.1    Voorberg, J.2    Meyer, D.3    Pannekoek, H.4    Pieto, G.5
  • 34
    • 0023863049 scopus 로고
    • The propeptide of von Willebrand factor independently mediates the assembly of von Willebrand multimers
    • 34. WISE, R.J., PITTMAN, D.D., HANDIN, R.I., KAUFMAN, R.J. and ORKIN, S.H. The propeptide of von Willebrand factor independently mediates the assembly of von Willebrand multimers. Cell 52, 229-236, 1988.
    • (1988) Cell , vol.52 , pp. 229-236
    • Wise, R.J.1    Pittman, D.D.2    Handin, R.I.3    Kaufman, R.J.4    Orkin, S.H.5
  • 35
    • 0345427143 scopus 로고
    • Expression of variant von Willebrand factor (vWF) cDNA in heterologous cells: Requirement of the pro-polypeptide in vWf multimer formation
    • 35. VERWEIJ, C.L., HART, M. and PANNEKOEK, H. Expression of variant von Willebrand factor (vWF) cDNA in heterologous cells: requirement of the pro-polypeptide in vWf multimer formation. EMBO J 6, 2885-2890, 1987.
    • (1987) EMBO J , vol.6 , pp. 2885-2890
    • Verweij, C.L.1    Hart, M.2    Pannekoek, H.3
  • 37
    • 0026561993 scopus 로고
    • Vicinal cysteines in the prosequence play a role in von Willebrand factor multimer assembly
    • 37. MAYADAS, T.N. and WAGNER, D.D. Vicinal cysteines in the prosequence play a role in von Willebrand factor multimer assembly. Proc Natl Acad Sci USA 89, 3531-3535, 1992.
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 3531-3535
    • Mayadas, T.N.1    Wagner, D.D.2
  • 38
    • 0024597022 scopus 로고
    • Effect of von Willebrand factor coexpression on the synthesis and secretion of factor VIII in chinese hamster ovary cells
    • 38. KAUFMAN, R.J., WASLEY, L.C., DAVIES, M.V., WISE, R.J., ISRAEL, D.I. and DORNER, A.J. Effect of von Willebrand factor coexpression on the synthesis and secretion of factor VIII in chinese hamster ovary cells. Mol Cell Biol 9, 1233-1242, 1989.
    • (1989) Mol Cell Biol , vol.9 , pp. 1233-1242
    • Kaufman, R.J.1    Wasley, L.C.2    Davies, M.V.3    Wise, R.J.4    Israel, D.I.5    Dorner, A.J.6
  • 39
    • 0027395949 scopus 로고
    • Biogenesis of von Willebrand factor-containing organelles in heterologous transfected CV-1 cells
    • 39. VOORBERG, J., FRONTIJN, R., CALAFAT, J., JANSSEN, H., VAN MOURIK, J.A. and PANNEKOEK, H. Biogenesis of von Willebrand factor-containing organelles in heterologous transfected CV-1 cells. EMBO J 12, 749-758, 1993.
    • (1993) EMBO J , vol.12 , pp. 749-758
    • Voorberg, J.1    Frontijn, R.2    Calafat, J.3    Janssen, H.4    Van Mourik, J.A.5    Pannekoek, H.6
  • 40
    • 0026649445 scopus 로고
    • Recombinant von Willebrand factor Arg578 -> Gln. A type IIB von Willebrand disease mutation affects binding to glycoprotein Ib but not to collagen or heparin
    • 40. RANDI, A.M., JORIEUX, S., TULEY, E.A., MAZURIER, C. and SADLER, J.E. Recombinant von Willebrand factor Arg578 -> Gln. A type IIB von Willebrand disease mutation affects binding to glycoprotein Ib but not to collagen or heparin. J Biol Chem 267, 21187-21192, 1992.
    • (1992) J Biol Chem , vol.267 , pp. 21187-21192
    • Randi, A.M.1    Jorieux, S.2    Tuley, E.A.3    Mazurier, C.4    Sadler, J.E.5
  • 41
    • 0025748557 scopus 로고
    • The role of von Willebrand factor multimers and propeptide cleavage in binding and stabilization of factor VIII
    • 41. WISE, R.J., DORNER, A.J., KRANE, M., PITTMAN, D.D. and KAUFMAN, R. The role of von Willebrand factor multimers and propeptide cleavage in binding and stabilization of factor VIII. J Biol Chem 266, 21948-21955, 1991.
    • (1991) J Biol Chem , vol.266 , pp. 21948-21955
    • Wise, R.J.1    Dorner, A.J.2    Krane, M.3    Pittman, D.D.4    Kaufman, R.5
  • 42
    • 0029042992 scopus 로고
    • Identification of amino acids residues essential for von Willebrand factor binding to platelet glycoprotein Ib
    • 42. MATSUSHITA, T. and SADLER, J.E. Identification of amino acids residues essential for von Willebrand factor binding to platelet glycoprotein Ib. J Biol Chem 270, 13406-13414, 1995.
    • (1995) J Biol Chem , vol.270 , pp. 13406-13414
    • Matsushita, T.1    Sadler, J.E.2
  • 43
    • 0029056138 scopus 로고
    • Role of the glycoprotein Ib-binding A1 repeat and the RGD sequence in platelet adhesion to human recombinant von Willebrand factor
    • 43. LANKHOF, H., WU, Y.P., VINK, T., SCHIPHORST, M.E., ZERWES, H.G., DE GROOT, G. and SIXMA, J.J. Role of the glycoprotein Ib-binding A1 repeat and the RGD sequence in platelet adhesion to human recombinant von Willebrand factor. Blood 86, 1035-1042, 1995.
    • (1995) Blood , vol.86 , pp. 1035-1042
    • Lankhof, H.1    Wu, Y.P.2    Vink, T.3    Schiphorst, M.E.4    Zerwes, H.G.5    De Groot, G.6    Sixma, J.J.7
  • 44
    • 0027093951 scopus 로고
    • O-linked carbohydrate of recombinant von Willebrand factor influences ristocetin-induced binding to platelet glycoprotein Ib
    • 44. CAREW, J.A., QUINN, S.M., START, J.H. and LYNCH, D.C. O-linked carbohydrate of recombinant von Willebrand factor influences ristocetin-induced binding to platelet glycoprotein Ib. J Clin Invest 90, 2258-2267, 1992.
    • (1992) J Clin Invest , vol.90 , pp. 2258-2267
    • Carew, J.A.1    Quinn, S.M.2    Start, J.H.3    Lynch, D.C.4
  • 46
    • 0027220469 scopus 로고
    • Type IIB mutation His-505-Asp implicates a new segment in the control of von Willebrand factor binding to platelet glycoprotein Ib
    • 46. RABINOWITZ, I., RANDI, A.M., SHINDLER, K.S., TULEY, E.A., RUSTAGI, P.K. and SADLER, J.E. Type IIB mutation His-505-Asp implicates a new segment in the control of von Willebrand factor binding to platelet glycoprotein Ib. J Biol Chem 268, 20497-20501, 1993.
    • (1993) J Biol Chem , vol.268 , pp. 20497-20501
    • Rabinowitz, I.1    Randi, A.M.2    Shindler, K.S.3    Tuley, E.A.4    Rustagi, P.K.5    Sadler, J.E.6
  • 47
    • 0025985412 scopus 로고
    • Definition of the affinity of binding between human von Willebrand factor and coagulation factor VIII
    • 47. GANZ, P.R., ATKINS, J.S., PALMER, D.S., DUDANI, A.K., HASHEMI, S. and LUISON, F. Definition of the affinity of binding between human von Willebrand factor and coagulation factor VIII. Biochem Biophys Res Comun 180, 231-237, 1991.
    • (1991) Biochem Biophys Res Comun , vol.180 , pp. 231-237
    • Ganz, P.R.1    Atkins, J.S.2    Palmer, D.S.3    Dudani, A.K.4    Hashemi, S.5    Luison, F.6
  • 48
    • 0026502835 scopus 로고
    • Evidence that a secondary binding and protecting site for factor VIII on von Willebrand factor is highly unlikely
    • 48. LAYET, S., GIRMA, J.P., OBERT, B., PEYNAUD-DEBAYLE, E., BIHOREAU, N. and MEYER, D. Evidence that a secondary binding and protecting site for factor VIII on von Willebrand factor is highly unlikely. Biochem J 282, 129-137, 1992.
    • (1992) Biochem J , vol.282 , pp. 129-137
    • Layet, S.1    Girma, J.P.2    Obert, B.3    Peynaud-Debayle, E.4    Bihoreau, N.5    Meyer, D.6
  • 49
    • 0027160385 scopus 로고
    • Variant von Willebrand disease with defective binding to factor VIII: The first case from Japan
    • 49. NISHINO, M., MIURA, S., YOSHIOKA, S., KUWAHARA, I., NISHIMURA, T., HAMADA, K., and FUKUI, H. Variant von Willebrand disease with defective binding to factor VIII: the first case from Japan. Intern J Hematol 57, 163-173, 1993.
    • (1993) Intern J Hematol , vol.57 , pp. 163-173
    • Nishino, M.1    Miura, S.2    Yoshioka, S.3    Kuwahara, I.4    Nishimura, T.5    Hamada, K.6    Fukui, H.7
  • 52
    • 0029035099 scopus 로고
    • The affinity and stoichiometry of binding of human factor VIII to von Willebrand factor
    • 52. VLOT, A.J., KOPPELMAN, S.J., VAN DEN BERG, M.H., BOUMA, B.N. and SIXMA, J.J. The affinity and stoichiometry of binding of human factor VIII to von Willebrand factor. Blood 85, 3150-3157, 1995.
    • (1995) Blood , vol.85 , pp. 3150-3157
    • Vlot, A.J.1    Koppelman, S.J.2    Van Den Berg, M.H.3    Bouma, B.N.4    Sixma, J.J.5


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