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Inhibition of T cell constimulation by VCAM-1 prevents murine graft-versus-host disease across minor histocompatibility barriers
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0028843985
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Pretreatment of donor mice with granulocyte colony-stimulating factor polarizes donor T lymphocytes toward type-2 cytokine production and reduces severity of experimental graft-versus-host disease
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Allogeneic transplants of canine peripheral blood stem cells mobilized by recombinant canine hematopoietic growth factors
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Sandmaier, B.M.1
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Different T-cell receptor repertoires between lesions and peripheral blood in acute graft-versus-host disease after allogeneic bone marrow transportation
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0029164624
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The significance of HLA-DRB1 matching on clinical outcome after HLA-A, B, DR identical unrelated donor marrow transplantation
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Unrelated donor bone marrow transplantation: Influence of HLA A and B incompatibility on outcome
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Davies, S.M.1
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Balduzzi A, Gooley T, Anasetti C, Sanders JE, Martin PJ, Petersdorf EW, Appelbaum FR, Buckner CD, Matthews D, Storb R, et al. Unrelated donor marrow transplantation in children. Blood. 86:1995;3247-3256.
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Balduzzi, A.1
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Petersdorf, E.W.6
Appelbaum, F.R.7
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Matthews, D.9
Storb, R.10
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35
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0029027351
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Identification of a graft versus host disease-associated human minor histocompatibility antigen
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of outstanding interest. See annotation [37].
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of outstanding interest den Haan JMM, Sherman NE, Blokland E, Huczko E, Koning F, Wouter Drijfhout J, Skipper J, Shabanowitz J, Hunt DF, Engelhard VH, Goulmy E. Identification of a graft versus host disease-associated human minor histocompatibility antigen. Science. 268:1995;1476-1480 See annotation [37].
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Den Haan, J.M.M.1
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36
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0029092140
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Human H-Y: A male-specific histocompatibility antigen derived from the SMCY protein
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of outstanding interest. See annotation [37].
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of outstanding interest Wang W, Meadows LR, den Haan JMM, Sherman NE, Chen Y, Blokland E, Shabanowitz J, Agulnik AI, Hendrickson RC, Bishop CE, et al. Human H-Y: a male-specific histocompatibility antigen derived from the SMCY protein. Science. 269:1995;1588-1590 See annotation [37].
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Wang, W.1
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37
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13344278000
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Mismatches of minor histocompatibility antigens between HLA-identical donors and recipients and the development of graft-versus-host disease after bone marrow transplantation
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of outstanding interest. Along with [35,36], this paper documents the identification of the peptide sequence of two mHCs and the demonstration of an association of GVHD with mHCs, both of which are exciting developments and will allow for further development of GVL strategies.
-
of outstanding interest Goulmy E, Schipper R, Pool J, Blokland E, Falkenburg JHF, Vossen JJ. Mismatches of minor histocompatibility antigens between HLA-identical donors and recipients and the development of graft-versus-host disease after bone marrow transplantation. N Engl J Med. 334:1996;281-285 Along with [35,36], this paper documents the identification of the peptide sequence of two mHCs and the demonstration of an association of GVHD with mHCs, both of which are exciting developments and will allow for further development of GVL strategies.
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Goulmy, E.1
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Vossen, J.J.6
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38
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0028903242
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Transplantation of allogeneic peripheral blood stem cell mobilized by recombinant human granulocyte colony-stimulating factor
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of special interest. See annotation [40].
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of special interest Bensinger WI, Weaver CH, Appelbaum FR, Rowley S, Demirer T, Sanders J, Storb R, Buckner CD. Transplantation of allogeneic peripheral blood stem cell mobilized by recombinant human granulocyte colony-stimulating factor. Blood. 85:1995;1655-1658 See annotation [40].
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39
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Primary transplantation of allogeneic peripheral blood progenitor cells mobilized by Filgrastim (granulocyte colony-stimulating factor)
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of special interest Schmitz N, Dreger P, Suttorp M, Rohwedder EB, Haferlach T, Löffler H, Hunter A, Russell NH. Primary transplantation of allogeneic peripheral blood progenitor cells mobilized by Filgrastim (granulocyte colony-stimulating factor). Blood. 85:1995;1666-1672 See annotation [40].
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40
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0029150223
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dim) and lymphoid subsets, and possible predictors of engraftment and graft-versus-host disease
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of special interest. The first reports of Phase II studies of allogenic PBSC transplantation [38-40]. Phase III studies are in progress but allogeneic PBSC transplantation appears promising.
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dim) and lymphoid subsets, and possible predictors of engraftment and graft-versus-host disease. Blood. 86:1995;2842-2848 The first reports of Phase II studies of allogenic PBSC transplantation [38-40]. Phase III studies are in progress but allogeneic PBSC transplantation appears promising.
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41
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Acute graft-versus-host disease: Grade and outcome in patients with chronic myelogenous leukemia
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Gratwohl A, Hermans J, apperley J, Arcese W, Bacigalupo A, Bandini G, di Bartolomeo P, Boogaerts M, Bosi A, Carreras E, et al. Acute graft-versus-host disease: grade and outcome in patients with chronic myelogenous leukemia. Blood. 86:1995;813-818.
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0029029246
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Consensus conference on acute GVHD grading
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43
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Methotrexate and cyclosporine compared with cyclosporine alone for prophylaxis of acute graft versus host disease after marrow transplantation for leukemia
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Storb R, Deeg HJ, Whitehead J, Appelbaum F, Beatty P, Bensinger W, Buckner CD, Clift R, Doney K, Farewell V, et al. Methotrexate and cyclosporine compared with cyclosporine alone for prophylaxis of acute graft versus host disease after marrow transplantation for leukemia. N Engl J Med. 314:1986;729-735.
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Marrow transplantation for severe aplastic anemia: Methotrexate alone compared with a combination of methotrexate and cyclosporine for prevention of acute graft-versus-host disease
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45
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0025087833
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What role for prednisone in prevention of acute graft-versus-host disease in patients undergoing marrow transplants?
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Storb R, Pepe M, Anasetti C, Appelbaum FR, Beatty P, Doney K, Martin P, Stewart P, Sullivan KM, Witherspoon R, et al. What role for prednisone in prevention of acute graft-versus-host disease in patients undergoing marrow transplants? Blood. 76:1990;1037-1045.
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Storb, R.1
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46
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0027365965
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Cyclosporine, methotrexate, and prednisone compared with cyclosporine and prednisone for prophylaxis of acute graft-versus-host disease
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Chao NJ, Schmidt GM, Niland JC, Amylon MD, Dagis AC, Long GD, Nademanee AP, Negrin RS, O'Donnell MR, Parker PM, et al. Cyclosporine, methotrexate, and prednisone compared with cyclosporine and prednisone for prophylaxis of acute graft-versus-host disease. N Engl J Med. 329:1993;1225-1230.
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47
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0028998878
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Tacrolimus (FK506) alone or in combination with methotrexate or methylprednisolone for the prevention of acute graft-versus-host disease after marrow transplantation from HLA-matched siblings: A single-center study
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of special interest. See annotation [48].
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of special interest Nash RA, Etzioni R, Storb R, Furlong T, Gooley T, Anasetti C, Appelbaum FR, Doney K, Martin P, Slattery J, et al. Tacrolimus (FK506) alone or in combination with methotrexate or methylprednisolone for the prevention of acute graft-versus-host disease after marrow transplantation from HLA-matched siblings: a single-center study. Blood. 85:1995;3746-3753 See annotation [48].
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Nash, R.A.1
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48
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15844395463
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FK506 (tacrolimus) monotherapy for prevention of graft-versus-host disease after histocompatible sibling allogeneic bone marrow transporation
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of special interest Fay JW, Wingard JR, Antin JH, Collins RH, Pineiro LA, Blazar BR, Saral R, Bierer BE, Przepiorka D, Fitzsimmons WE, et al. FK506 (tacrolimus) monotherapy for prevention of graft-versus-host disease after histocompatible sibling allogeneic bone marrow transporation. Blood. 87:1996;3514-3519 References [47,48] represent the first reports of the use of tacrolimus (FK506) for the prevention of acute GVHD.
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Fay, J.W.1
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49
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11944270723
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Modulation of acute graft-versus-host disease after allogeneic bone marrow transplantation by tumor necrosis factor α (TNFα) release in the course of pretransplant conditioning: Role of conditioning regimens and prophylactic application of a monoclonal antibody neutralizing human TNFα (MAK 195F)
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Holler E, Kolb HJ, Mittemüller J, Kaul M, Ledderose G, Duell T, Seeber B, Schleuning M, Hintemeier-Knabe R, Ertl B, et al. Modulation of acute graft-versus-host disease after allogeneic bone marrow transplantation by tumor necrosis factor α (TNFα) release in the course of pretransplant conditioning: role of conditioning regimens and prophylactic application of a monoclonal antibody neutralizing human TNFα (MAK 195F). Blood. 86:1995;890-899.
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50
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0000642263
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A Phase II/III randomized, double-blind, placebo-controlled multicenter trial of humanized anti-TAC for prevention of acute graft-versus-host disease (GVHD) in recipients of marrow transplants from unrelated donors [abstract]
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51
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Effect of T-cell depletion as graft-versus-host disease prophylaxis on engraftment, relapse, and disease-free survival in unrelated marrow transplantation for chronic myelogenous leukemia
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0025087325
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A retrospective analysis of therapy for acute graft-versus-host disease: Initial treatment
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56
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0028860890
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Treatment of acute graft-versus-host disease with methylprednisolone and cyclosporine with or without an anti-interleukin-2 receptor monoclonal antibody
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57
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8044219688
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Evaluation of a CD5-specific immunotoxin for treatment of acute graft-versus-host disease after allogeneic marrow transplantation
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Martin PJ, Nelson BJ, Appelbaum FR, Anasetti C, Deeg HJ, Hansen JA, McDonald GB, Nash RA, Sullivan KM, Witherspoon RP, et al. Evaluation of a CD5-specific immunotoxin for treatment of acute graft-versus-host disease after allogeneic marrow transplantation. Blood. 1996;. in press.
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Martin, P.J.1
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58
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Response of steroid-resistant graft-versus-host disease to lymphoblast antibody CBL1
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59
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0028840974
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Thalidomide as salvage therapy for chronic graft-versus-host disease
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of special interest. A report on another potentially valuable agent for the treatment of chronic GVHD.
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of special interest Parker PM, Chao N, Nademanee A, O'Donnell Mr, Schmidt GM, Snyder DS, Stein AS, Smith EP, Molina A, Stepan DE, et al. Thalidomide as salvage therapy for chronic graft-versus-host disease. Blood. 86:1995;3604-3609 A report on another potentially valuable agent for the treatment of chronic GVHD.
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60
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0029100438
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Graft-versus-leukemia effect of donor transfusions in marrow grafted patients
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of special interest. An important report expanding the experience of donor lymphocyte infusions for CML patients in relapse and now including patients with acute myeloid leukemia, acute lymphocytic leukemia and myelodysplastic syndrome in relapse after transplant.
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of special interest Kolb HJ, Schattenberg A, Goldman JM, Hertenstein B, Jacobsen N, Arcese W, Ljungman P, Ferrant A, Verdonck L, Niederwieser D, et al. Graft-versus-leukemia effect of donor transfusions in marrow grafted patients. Blood. 86:1995;2041-2050 An important report expanding the experience of donor lymphocyte infusions for CML patients in relapse and now including patients with acute myeloid leukemia, acute lymphocytic leukemia and myelodysplastic syndrome in relapse after transplant.
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0029092530
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Adoptive immunotherapy evaluating escalating doses of donor leukocytes for relapse of chronic myeloid leukemia after bone marrow transplantation: Separation of graft-versus-host leukemia responses from graft-versus-host disease
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