The I protein of the heterogeneous nuclear ribonucleoprotein complex is a novel dog nuclear autoantigen

Journal of Autoimmunity

Volumn 9, Issue 5, 1996, Pages 599-608

  Soulard, Michel ^a   Della Valle, Véronique ^a   Monod, Guillaume ^a   Prélaud, Pascal ^b   Lacroix, Jean Claude ^c   Larsen, Christian Jacques ^a  

^a INSERM   (France)

^b Ctr d'Etud et de Rech en Immunol   (France)

^c SORBONNE UNIVERSITÉ   (France)

Author keywords

Canine autoantibodies; hnRNP proteins; Lupus like syndromes; RNA binding proteins

Indexed keywords

AUTOANTIBODY; AUTOANTIGEN; GUANINE NUCLEOTIDE BINDING PROTEIN; RIBONUCLEOPROTEIN;

ANIMAL EXPERIMENT; ARTICLE; AUTOIMMUNITY; DIAGNOSIS; DOG; ETIOLOGY; FEMALE; IMMUNOBLOTTING; LUPUS VULGARIS; NONHUMAN; POLYARTHRITIS; PRIORITY JOURNAL;

EID: 0030271664     PISSN: 08968411     EISSN: None     Source Type: Journal    
DOI: 10.1006/jaut.1996.0079     Document Type: Article

References (49)

1. 1. Tan E.M. 1989. Antinuclear antibodies. In Advances in Immunology. F.J. Dixon, ed., Academic Press, San Diego, pp. 93-151
2. 2. Huston D.P., Steinberg A.D. 1979. Animal models of human systemic lupus. Yale J. Biol. Med. 52: 289-305
3. 3. Lewis R.M., Schwartz R., Henry W.B. 1965. Canine systemic lupus erythematosus. Blood 25: 143-160
4. 4. Lewis R.M. 1972. Animal model of human disease: canine systemic lupus erythematosus. Am. J. Path. 69: 537-540
5. 5. Scott D.W., Walton D.K., Manning T.O., Smith C.A., Lewis R.M. 1982. Canine lupus erythematosus. I. Systemic lupus erythematosus. J.A.A.H.A. 19: 461-479
6. 6. Costa O., Fournel C., Lotchouanang E., Monier J.C., Fontaine M. 1984. Specificities of antinuclear antibodies detected in dogs with SLE. Vet. Immunol. Immunopathol. 47: 369-382
7. 7. Brinet A., Fournel C., Faure J.R., Venet C., Monier J.C. 1988. Anti-histone antibodies (ELISA) and immunoblot in canine lupus erythematosus. Clin. Exp. Immunol. 74: 105-109
8. 8. Monier J.C., Dardenne M., Rigal D., Costa O., Fournel C., Lapras M. 1980. Clinical and laboratory features of canine lupus syndromes. Arthritis Rheum. 23: 294-301
9. 9. Monier J.C., Ritter J., Caux C., Chabanne L., Fournel C., Venet C., Rigal D. 1992. Canine systemic lupus erythematosus: antinuclear antibodies. Lupus. 1: 287-293
10. 125I-labelled DNA binding test. Clin. Exp. Immunol. 26: 425-430
11. 11. Lerner N.R., Steitz J.A. 1979. Antibodies to small nuclear RNAs complexed with proteins are produced by patients with systemic lupus erythematosus. Proc. Natl. Acad. Sci. USA 76: 5495-5499
12. 12. Dreyfuss G., Matunis M.J., Pinol-Roma S., Burd C. 1993. HnRNP proteins and the biogenesis of mRNA. Annu. Rev. Biochem. 62: 289-321
13. 13. Choi Y.D., Dreyfuss G. 1984. Monoclonal antibody characterization of the C proteins of heterogeneous nuclear ribonucleoprotein complexes in vertebrate cells. J. Cell Biol. 99: 1997-2004
14. 14. Frizler M.J., Ali R., Tan E.M. 1984. Antibodies from patients with mixed connective tissue disease react with a heterogeneous nuclear ribonucleoprotein or ribonucleic acid of the nuclear matrix. J. Immunol. 132: 1216-1222
15. 15. Montecucco C., Caporali R., Negri C., De Gennaro F., Cerino A., Bestagno M., Cobianchi F., Astaldi-Ricotti G. 1990. Antibodies from patients with rheumatoid arthritis and systemic lupus erythematosus recognize different epitopes of a single heterogeneous nuclear RNP core protein. Arthritis Rheum. 33: 180-186
16. 16. Astaldi-Ricotti G., Bestagno M., Cerino A., Negri C., Caporali R., Cobianchi F., Longhi F., Montecucco C. 1989. Antibodies to hnRNP core protein A1 in connective tissue diseases. J. Cell Biochem. 40: 1-5
17. 17. Kirstein H., Mathiesen F. 1987. Anti-keratin antibodies in rheumatoid arthritis: methods and clinical significance. Scand. J. Rheumatol. 16: 331-337
18. 18. Hassfeld W., Steiner G., Hartmuth K., Kolarz G., Scherak O., Graninger W., Thumb N., Smolen J. 1989. Demonstration of a new antinuclear antibody (anti-RA33) that is highly specific for rheumatoid arthritis. Arthritis Rheum. 32: 1515-1520
19. 19. Steiner G., Hartmuth K., Skriner I., Maurer-Fogy I., Sinski A., Thalmann E., Hassfeld W., Barta A., Smolen J. 1992. Purification and partial sequencing of the nuclear autoantigen RA33 shows that it is indistinguishable from the A2 protein of the heterogeneous nuclear ribonucleoprotein complex. J. Clin. Invest. 90: 1061-1066
20. 20. Soulard M., Barque J.P., Della Valle V., Hernandez-Verdun D., Massen C., Danon F., Larsen C.J. 1991. A novel 43-kDa glycoprotein is detected in the nucleus of mammalian cells by autoantibodies from dogs with autoimmune disorders. Exp. Cell Res. 193: 59-71
21. 21. Soulard M., Della Valle V., Siomi M.C., Pinol-Roma S., Codogno P., Bauvy C., Bellini M., Lacroix J.C., Monod G., Dreyfuss G., Larsen C.J. 1993. HnRNP G: sequence and characterization of a glycosylated RNA-binding protein. Nucleic Acids Res. 21: 4210-4217
22. 22. Gil A., Sharp P.A., Jamison S.F., Garcia-Blanco M.A. 1991. Characterization of cDNAs encoding the polypyrimidine tract-binding protein. Genes Dev. 5: 1224-1236
23. 23. Patton J.G., Mayer S.A., Tempst P., Nadal-Ginard B. 1991. Characterization and molecular cloning of polypyrimidine tract-binding protein: a component of a complex necessary for pre-mRNA splicing. Genes Dev. 5: 1237-1251
24. 24. Guetti A., Pinol-Roma S., Michael W.M., Morandi C., Dreyfuss G. 1992. HnRNP I, the polypyrimidine tract-binding protein: distinct nuclear localization and association with hnRNAs. Nucleic Acids Res. 20: 3671-3678
25. 25. Kumer V., Krasny S., Beutner E.H. 1985. Specificity of the Crithidia luciliae method for detecting anti-DNA antibodies. Effect of absorption for lipoproteins. Immunol. Invest. 14: 199-210
26. 26. Soulard M., Lagaye S., Della Valle V., Danon F., Larsen C.J., Barque J.P. 1989. Nucleolar proteins identified in human cells as antigen by sera from dog with autoimmune disorders. Exp. Cell Res. 182: 482-498
27. 27. Barque J.P., Lagaye S., Ladoux A., Della Valle V., Abita J.P., Larsen C.J. 1987. PSL, a nuclear cell cycle associated antigen is increased during retinoic-induced differentiation of HL-60 cells. Biochem. Biophys. Res. Commun. 147: 993-997
28. 28. Pinol-Roma S., Choi Y., Matunis M., Dreyfuss G. 1988. Immunopurification of heterogeneous nuclear ribnonucleoprotein particles reveals an assortment of RNA-binding proteins. Genes Dev. 2: 215-227
29. 29. Cleveland D.W., Fischer S.G., Kirchner M.W., Laemli U.K. 1977. Peptide mapping by limited proteolysis in sodium dodecyl sulfate and analysis by gel electrophoresis. J. Biol. Chem. 252: 1102-1109
30. 30. Sambrook J., Fritsch E.F., Maniatis T. 1989. Molecular cloning: A Laboratory Manual. 2nd ed. Cold Spring Harbor Lab. Press, Plainview, NY
31. 31. Sanger F., Nicklen S., Coulson A.R. 1977. DNA sequencing with chain-terminating inhibitors. Proc. Natl. Acad. Sci. USA 74: 5463-5467
32. 32. Lacroix J.C., Azzouz A., Boucher D., Abbadie C., Pyne K., Charlemagne J. 1985. Monoclonal antibodies to lampbrush chromosome antigens of Pleurodeles waltl. Chromosoma 92: 69-80
33. 33. Pinol-Roma S., Swanson M., Gall J., Dreyfuss G. 1989. A novel heterogeneous nuclear RNP protein with a unique distribution on nascent transcripts. J. Cell Biol. 109: 2575-2587
34. 34. Wilk H., Werr H., Suedrich D., Kiltz H., Schäfer K. 1985. The core proteins of 35S hnRNP complexes. Eur. J. Biochem. 146: 71-81
35. 35. Holcomb E., Friedman D. 1984. Phosphorylation of the C-proteins of HeLa cell hnRNP particles. J. Biol. Chem. 259: 31-40
36. 36. Burd C., Swanson M., Görlach M., Dreyfuss G. 1989. Primary structures of the heterogeneous nuclear ribonucleoprotein A2, B1, and C2 proteins: a diversity of RNA binding proteins is generated by small peptide inserts. Proc. Natl. Acad. Sci. USA 86: 9788-9792
37. 37. Swanson M., Nakagawa T., Levan K., Dreyfuss G. 1987. Primary structure of human nuclear ribnonucleoprotein particle C proteins: conservation of sequence and domain structures in heterogeneous nuclear RNA, mRNA, and pre-rRNA binding proteins. Mol. Cell Biol. 7: 1731-1739
38. 38. Matunis M.J., Xing J., Dreyfuss G. 1994. The hnRNP F protein: unique primary structure, nucleic acid-binding properties, and subcellular localization. Nucleic Acids Res. 22: 1059-1067
39. 39. Bennett M., Pinol-Roma S., Staknis D., Dreyfuss G., Reed R. 1992. Differential binding of heterogeneous nuclear ribonucleoproteins to mRNA precursors prior to spliceosome assembly in vitro. Mol. Cell Biol. 7: 3165-3175
40. 40. Pinol-Roma S., Dreyfuss G. 1992. Shuttling of pre-mRNA binding proteins between nucleus and cytoplasm. Nature (Lond.) 335: 730-732
41. 41. Pinol-Roma S., Dreyfuss G. 1991. Transcription-dependent and transcription-independent nuclear transport of hnRNP proteins. Science (Wash. DC) 253: 312-314
42. 42. Hellen C.U., Witherell G.W., Schmid M., Shin S.H., Pestova T.V., Gil A., Wimmer E. 1993. A cytoplasmic 57 kDa protein that is required for translation of picornavirus RNA by internal ribosomal entry is identical to the nuclear pyrimidine tract-binding protein. Proc. Natl Acad. Sci. USA 90: 7642-7646
43. 43. Lewis R., Schwartz A., Harris G., Hirsch M., Black P., Schwartz R. 1973. Canine SLE transmission of serologic abnormalities by all free filtrates. J. Clin. Invest. 52: 1892-1907
44. 44. Quimby F., Gebert R., Datta S., Andre-Schwartz J., Tannenberg W., Lewis R., Weinstein I., Schwartz R. 1978. Characterization of a retrovirus that cross reacts serologically with canine and human SLE. Clin. Immunol. Immunopathol. 9: 194-210
45. 45. Lewis R., Tannenberg W., Smith C., Schwartz R. 1974. C-type viruses in systemic lupus erythematosus. Nature (Lond.) 252: 79-81
46. 46. Trauger R., Talbott R., Wilson S., Karpel R., Elder J. 1990. A single-stranded nucleic acid binding sequence common to the heterogeneous nuclear ribonucleoparticle protein A1 and murine recombinant virus gp70. J. Biol. Chem. 265: 3674-3678
47. 47. Perl A., Colombo E., Dai H., Agarwal R., Mark K.A., Banki K., Poiesz B.J., Phillips P.E., Hoch S.O., Reveille J.D., Arnett F.C. 1995. Antibody reactivity to the HRES-1 endogenous retroviral element identifies a subset of patients with systemic lupus erythematosus and overlap syndromes. Arthritis Rheum. 38: 1660-1671
48. 48. Hubert B., Teichner M., Fournel C., Monier J.C. 1988. Spontaneous familial systemic lupus erythematosus in a canine breeding colony. J. Comp. Path. 98: 81-89
49. 49. Teichner M., Krumbacher K., Doxiadis I., Doxiadis G., Fournel C., Rigal D., Monier J.C., Grosse-Wilde H. 1990. Systemic lupus erythematosus in dogs: association to the major histocompatibility complex class I antigen DLA-A7. Clin. Immunol. Immunopathol. 55: 255-262