AMP degradation in the perfused rat heart during 2-deoxy-D-glucose perfusion and anoxia. Part II: The determination of the degradation pathways using an adenosine deaminase inhibitor

Journal of Molecular and Cellular Cardiology

Volumn 28, Issue 10, 1996, Pages 2175-2182

  Chen, Weina ^a,b   Guéron, Maurice ^a  

^a ECOLE POLYTECHNIQUE   (France)

^b NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

Author keywords

2 deoxy D glucose; Adenosine deaminase; AMP deaminase; Anoxia; EHNA; Isolated rat heart; NMR

Indexed keywords

9 (2 HYDROXY 3 NONYL)ADENINE; ADENOSINE; ADENOSINE DEAMINASE INHIBITOR; ADENOSINE MONOPHOSPHATE DEAMINASE; ADENOSINE PHOSPHATE; DEOXYGLUCOSE; INOSINE; INOSINE PHOSPHATE; PHOSPHATE; PURINE;

ANIMAL TISSUE; ANOXIA; ARTICLE; CATABOLISM; CONTROLLED STUDY; DEGRADATION; HEART; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; ISOLATED HEART; MALE; NONHUMAN; PERFUSION; PHOSPHORUS NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; RAT;

ANIMALIA;

EID: 0030271611     PISSN: 00222828     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmcc.1996.0209     Document Type: Article

References (20)

1. ACHTERBERG FW, HARMSEN EEF, DE JONG WJ, 1985. Adenosine deaminase inhibition and myocardial purine release during normoxia and ischemia. Cordiol Res 19: 593-598.
2. ARABADJIS PG, TULLSON PC, TERJUNG L, 1993. Purine nucleoside formation in rat skeletal muscle fiber types. Am J Physiol 264: C1246-1251.
3. BARSACCHI R, RANISRI-RAGGI M, BERGAMINI C, RAGGI A, 1979. Adenylate metabolism in the heart: Regulatory properties of rabbit cardiac adenylate deaminase. Biochem J 184: 361-366.
4. CHEN W, HOERTER JA, GUERON G, 1996. A comparison of AMP degradation in the perfused rat heart during 2-deoxy-D-glucose perfusion and anoxia. Part I: the release of adenosine and inosine. J Mol Cell Cardiol, in press.
5. FISHBEIN WN, DAVIS JI, FOELLMER JW, 1983. Comparative enzymology of AMP deaminase, adenylate kinase, and creatine kinase in vertebrate heart and skeletal muscle: the characteristic AMP deaminase levels of skeletal versus cardiac muscle are reversed in the North American toad. J Camp Physiol B 163: 175-181.
6. 31P-NMR study. Am J Physiol 255: C192-C201.
7. HUMPHREY SM, HOLLISS DG, SEELYE RN, 1984. Adenine pool catabolism in the ischemic, the calcium-depleted ischemic, and substrate free anoxic isolated rat hearts: relationship to contracture development. J Mol Cell Cardiol 16: 1127-1136.
8. JENNINGS RB, REIMER KA, HILL ML, MAYER SE, 1981. Total ischemia in dog hearts in vitro. 1. Comparison of high energy phosphate production, utilization, and depletion, and of adenine nucleotide catabolism in total ischemia in vitro cs. severe ischemia in vivo. Circ Res 49: 892-900.
9. KELETHA K, STANKIEWICZ A, MAKAREWICZ W, ZYDOWO M, 1976. The influence of phosphate, fluoride and potassium ions on the activity of AMP-deaminase from human skeletal muscle. Intl J Biochem 7: 67-71.
10. 1 receptors by G proteins in rat ventricular myocytes. Am J Physiol 259: H820-H826.
11. NEWSHOLME EA, LEECH AR, 1983. Biochemistry for the Medical Sciences. John Wiley & Sons Publisher, Chapter 7, p315.
12. RICHARDT G, WAAS W, KRANZHOFER R, MAYER E, SCHOMING A, 1987. Adenosine inhibits exocytoic release of endogenous noradrenaline in rat heart: a protective mechanism in early myocardial ischemia. Circ Res. 61: 117-123, 1987.
13. SAHLIN K, GORSKI J, EDSTROM L, 1990. Influence of ATP turnover and metabolites changes on IMP formation and glycolysis in rat skeletal muscle. Am J Physiol 259: C409-C412.
14. SMOLENSKI RT, SUITTERS A, YACOUB MH, 1992. Adenine nucleotide catabolism and adenosine formation in isolated human cardiomyocytes. J Mol Cell Cardiol 24: 91-96.
15. SOUSSI B, LAGERWALL K, IDSTROM JP, SCHERSTEN T, 1993. Purine metabolic pathways in rat hindlimb perfusion model during ischemia and reperfusion. Am J Physiol 265: H1074-H1081.
16. SPYCHALA J, MARSZALEK J, 1991. Regulatory properties of AMP deaminases from rat tissues. Int J Biochem 23: 1155-1159.
17. THAKKAR JK, JANERO DR, YARWOOD C, SHARIF H, HENIUK D, 1993a. Isolation and characterization of AMP diaminase from mammalian (rabbit) myocardium. Biochem J 290: 335-341.
18. TULLSON PC, BANGSBO J, HELLSTEN Y, RICHTER EA, 1995. IMP metabolism in human skeletal muscle after exhaustive exercise. J Appl Physiol 78: 146-152.
19. WAGENKNECHT B, LEIBERMAN M, 1991. Adenine nucleotide degradation in cultured chick heart muscle cells. Mol Cell Biochem 107: 119-125.
20. ZOREF-SHANI E, KESSLER-ICEKSON G, SPERLING O, 1988. Pathways of adenine nucleotide catabolism in primary rat cardiomyocytes cultures. J Mol Cell Cardiol 20: 23-33.