Molecular chaperones and protein folding in plants

Plant Molecular Biology

Volumn 32, Issue 1-2, 1996, Pages 191-222

  Boston, Rebecca S ^a   Viitanen, Paul V ^b   Vierling, Elizabeth ^c  

^a NORTH CAROLINA STATE UNIVERSITY   (United States)

^b DUPONT COMPANY   (United States)

^c University of Arizona   (United States)

Author keywords

BiP; calnexin; foldases; heat shock proteins; protein disulfide isomerase; protein transport

Indexed keywords

EID: 0030267627     PISSN: 01674412     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF00039383     Document Type: Article

References (343)

1. Ajir-Shapira D, Leustek T, Dalie B, Weissbach H, Brot N: Hsp70 proteins, similar to Escherichia coli DnaK, in chloroplasts and mitochondria of Euglena gracilis. Proc Natl Acad Sci 87: 1749-1752 (1990).
2. Aligue R, Akhavan-Niak H, Russell P: A role for Hsp90 in cell cycle control: weel tyrosine kinase activity requires interaction with Hsp90. EMBO J 13: 6099-6106 (1994).
3. 2+-permeable slow vacuolar ion channel of stomatal guard cells. Plant Cell 7: 1473-1483 (1995).
4. Allen NS, Tiwari SC: Localization of calreticulin, a major calcium binding protein, in plant cells. Plant Physiol 96 (suppl): 42 (1991).
5. Anderson JV, Haskell DW, Guy CL: Differential influence of ATP on native spinach 70-kilodalton heat-shock cognates. Plant Physiol 104: 1371-1380 (1994).
6. Anderson JV, Li Q, Haskell DW, Guy CL: Structural organization of the spinach endoplasmic reticulum-luminal 70-kDa heat shock cognate gene and expression of 70-kDa heat-shock genes during cold acclimation. Plant Physiol 104: 1359-1370 (1994).
7. Arrigo A-P, Landry J: Expression and function of the low-molecular weight heat shock proteins. In: Morimoto R, Tissieres A, Georgopolous C (eds), The Biology of Heat Shock Proteins and Molecular Chaperones, pp. 335-373. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY 1994.
8. 2 chaperonin hetero-oligomer. Science 265: 653-656 (1994).
9. Baneyx F, Bertsch U, Kalbach CE, Van der Vies SM, Soll J, Gatenby AA: Spinach chloroplast cpn21 co-chaperonin possesses two functional domains fused together in a toroidal structure and exhibits nucleotide-dependent binding to plastid chaperonin 60. J Biol Chem 270: 10695-10702 (1995).
10. Barraclough R, Ellis RJ: Protein synthesis in chloroplasts. IX. Assembly of newly-synthesized large subunits into ribulose bisphosphate carboxylase in isolated intact pea chloroplasts. Biochim Biophys Acta 608: 19-31 (1980).
11. Bates EEM, Vergne P, Dumas C: Analysis of the cytosolic hsp70 gene family in Zea mays. Plant Mol Biol 25: 909-916 (1994).
12. Bednarek SY, Raikhel NV: Intracellular trafficking of secretory proteins. Plant Mol Biol 20: 133-150 (1992).
13. Bertsch U, Soll J: Functional analysis of isolated cpn10 domains and conserved amino acid residues in spinach chloroplast co-chaperonin by site-directed mutagenesis. Plant Mol Biol 29: 1039-1055 (1995).
14. Bertsch U, Soll J, Seetharam R, Viitanen PV: Identification, characterization, and DNA sequence of a functional 'double' groES- like chaperonin from chloroplasts of higher plants. Proc Natl Acad Sci USA 89: 8696-8700 (1992).
15. Bessoule J-J: Occurrence and sequence of a DnaJ protein in plant (Allium porrum) epidermal cells. FEBS Lett 323: 51-54 (1993).
16. Blond-Elguindi S, Cwirla SE, Dower WJ, Lipshutz RJ, Sprang SR, Sambrook JF, Gething M-JH: Affinity panning of a library of peptides displayed on bacteriophages reveals the binding specificity of BiP. Cell 75: 717-728 (1993).
17. Blond-Elguindi S, Fourie AM, Sambrook JF, Gething M-JH: Peptide-dependent stimulation of the ATPase activity of the molecular chaperone BiP is the result of conversion of oligomers to active monomers. J Biol Chem 268: 12730-12735 (1993).
18. Bloom MV, Milos P, Roy H: Light-dependent assembly of ribulose-1,5-bisphosphate carboxylase. Proc Natl Acad Sci USA 80: 1013-1017 (1983).
19. Bohen SP, Kralli A, Yamamoto KR: Hold 'em and fold 'em: chaperones and signal transduction. Science 268: 1303-1304 (1995).
20. Boorstein WR, Ziegelhoffer T, Craig EA: Molecular evolution of the HSP70 multigene family. J Mol Evol 38: 1-17 (1994).
21. Bork P, Sander C, and Valencia A: An ATPase domain common to prokaryotic cell cycle proteins, sugar kinases, actin, and hsp70 heat shock proteins. Proc Natl Acad Sci USA 89: 7290-7294 (1992).
22. Boston RS, Fontes EBP, Shank BB, Wrobel RL: Increased expression of the maize immunoglobulin binding protein homologue b-70 in three zein regulatory mutants. Plant Cell 3: 497-505 (1991).
23. Boston RS, Gillikin JW, Wrobel RL: Coordinate induction of three luminal ER-stress proteins in maize endosperm mutants. J Cell Biochem 19A: 143 (1995).
24. Braig K, Otwinowski Z, Hegde R, Boisvert DC, Joachimiak A, Horwich AL, Sigler PB: The crystal structure of the bacterial chaperonin GroEL at 2.8 å. Nature 371: 578-586 (1994).
25. Brot N, Redfield B, Qiu N-H, Chen G-J, Vidal V, Carlino A, Weissbach H: Similarity of nucleotide interactions of BiP and GTP-binding proteins. Proc Natl Acad Sci USA 91: 12120-12124 (1994).
26. Buchner J, Schmidt M, Fuchs M, Jaenicke R, Rudolph R, Schmid FX, Kiebhaber T: GroE facilitates refolding of citrate synthase by suppressing aggregation. Biochemistry 30: 1586-1591 (1991).
27. Bulleid N, Freedman R: Defective co-translational formation of disulfide bonds in protein disulphide isomerase-deficient microsomes. Nature 335: 649-651 (1988).
28. Burt WJE, Leaver CJ: Identification of a chaperonin-10 homologue in plant mitochondria. FEBS Lett 339: 139-141 (1994).
29. Cabané M, Calvet P, Vincens P, Boudet AM: Characterization of chilling-acclimation-related proteins in soybean and identification of one as a member of the heat shock protein (HSP 70) family. Planta 190: 346-353 (1993).
30. Cannon S, Wang P, Roy H: Inhibition of ribulose bisphosphate carboxylase by antibody to a binding protein. J Cell Biol 103: 1327-1335 (1986).
31. Carazo JM, Marco S, Abella G, Carrascosa JL, Secilla J-P, Muyal M: Electron microscopy study of GroEL chaperonin: different views of the aggregate appear as a function of cell growth temperature. J Struct Biol 106: 211-220 (1991).
32. Ceriotti A, Pedrazzini E, Bielli A, Giovinazzo G, Bollini R, Vitale A: Assembly and intracellular transport of phaseolin, the major storage protein of Phaseolus vulgaris. J Plant Physiol 145: 648-653 (1995).
33. Chandrasekhar GN, Tilly K, Woolford C, Hendrix R, Georgopoulos C: Purification and properties of the groES morphogenetic protein of Escherichia coli. J Biol Chem 261: 12414-12419 (1986).
34. Chang H-CJ, Lindquist S: Conservation of Hsp90 macromolecular complexes in Saccharomyces cerevisiae. J Biol Chem 269: 24983-24988 (1994).
35. Chen F, Hayes PM, Mulrooney DM, Pan A: Identification and characterization of cDNA clones encoding plant calreticulin in barley. Plant Cell 6: 835-843 (1994).
36. 1 core. Proc Natl Acad Sci USA 91: 11497-11501 (1994).
37. Chen Q, Lauzon LM, DeRocher AE, Vierling E: Accumulation, stability, and localization of a major chloroplast heat-shock protein. J Cell Biol 110: 1873-1883 (1990).
38. Chen Q, Vierling E: Analysis of conserved domains identifies a unique structural feature of a chloroplast heat shock protein. Mol Gen Genet 226: 425-431 (1991).
39. Chen X, Sullivan DS, Huffaker TC: Two yeast genes with similarity to TCP-1 are required for microtubule and actin function in vivo. Proc Natl Acad Sci USA 91: 9111-9115 (1994).
40. Cheng MY, Hartl F-U, Martin J, Pollock RA, Kalousek F, Neupert W, Hallberg EM, Hallberg RL, Horwich AL: The mitochondrial chaperonin hsp60 is essential for assembly of protein imported into yeast mitochondria. Nature 337: 620-625 (1989).
41. +]. Science 268: 880-884 (1995).
42. 4 monocotyledons. Physiol Plant 92: 118-130 (1994).
43. Cloney LP, Bekkaoui DR, Wood MG, Hemmingsen SM: Assessment of plant chaperonin-60 gene function in Escherichia coli. J Biol Chem 267: 23333-23336 (1992).
44. Cloney LP, Wu HB, Hemmingsen SM: Expression of plant chaperonin-60 genes in Escherichia coli. J Biol Chem 267: 23327-23332 (1992).
45. Coleman CE, Lopes MA, Gillikin JW, Boston RS, Larkins BA: A defective signal peptide in the maize high-lysine mutant floury 2. Proc Natl Acad Sci USA 92: 6828-6831 (1995).
46. Conner TW, LaFayette PR, Nagao RT, Key JL: Sequence and expression of a HSP83 from Arabidopsis thaliana. Plant Physiol 94: 1689-1695 (1990).
47. Cordewener JHG, Hause G, Görgen E, Busink R, Hause B, Dons HJM, van Lammeren AAM, van Lockeren Campagne MM, Pechan P: Changes in synthesis and localization of members of the 70-kDa class of heat-shock proteins accompany the induction of embryogenesis in Brassica napus L. microspores. Planta 196: 747-755 (1995).
48. Coughlan SJ, Hastings C, Winfrey JR: Molecular characterization of plant endoplasmic reticulum: identification of protein disulfide-isomerase as the major reticuloplasmin. Eur J Biochem 235: 215-244 (1996).
49. Craig EA: Regulation and function of the HSP70 multigene family of Saccharomyces cerevisiae. In: Morimoto RI, Tissières A, Georgopoulos C (eds), Stress Proteins in Biology and Medicine, pp. 301-321. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY (1990).
50. Craig EA, Baxter BK, Becker J, Halladay J, Ziegelhoffer T: Cytosolic hsp70s of Saccharomyces cerevisiae: roles in protein synthesis, protein translocation, proteolysis, and regulation. In Morimoto RI, Tissières A, Georgopoulos C (eds) The Biology of Heat Shock Proteins and Molecular Chaperones, pp. 31-52. Cold Spring Harbor Press, Cold Spring Harbor, NY (1994).
51. Craig EA, Gambill BD, Nelson RJ: Heat shock proteins: molecular chaperones of protein biogenesis. Microbiol Rev 57: 402-414 (1993).
52. 2+ ATPases. J Cell Biol 124: 351-363 (1994).
53. Cutforth T, Rubin GM: Mutations in Hsp83 and cdc37 impair signaling by the sevenless receptor tyrosine kinase in Drosophila. Cell 77: 1027-1036 (1994).
54. Cyr DM, Langer T, Douglas MG: DnaJ-like proteins: molecular chaperones and specific regulators of Hsp70. Trends Biochem Sci 19: 176-181 (1994).
55. Czar MJ, Lyons RH, Welsh MJ, Renoir JM, Pratt WB: Evidence that the FK506-binding immunophilin heat shock protein 56 is required for trafficking of the glucocorticoid receptor from the cytoplasm to the nucleus. Mol Endocrinol 9: 1549-1560 (1995).
56. D'Amico L, Valsasina B, Daminati MG, Fabrini MS, Nitti G, Bollini R, Ceriotti A, Vitale A: Bean homologoues of the mammalian glucose regulated proteins: induction by tunicamycin and interaction with newly-synthesized storage proteins in the endoplasmic reticulum. Plant J 2: 443-455 (1992).
57. Delmer DP, Amor Y: Cellulose biosynthesis. Plant Cell 7: 987-1000 (1995).
58. Delmer DP, Volokita M, Solomon M, Fritz U, Delphendahl W, Herth W: A monoclonal antibody recognizes a 65 kDa higher plant membrane polypeptide which undergoes cation-dependent association with callose synthase in vitro and colocalizes with sites of high callose deposition in vivo. Protoplasma 176: 33-42 (1993).
59. Denecke J, Carlsson LE, Vidal S, Höglund A-S, Ek B, Van Zeijl MJ, Sinjorgo KMC, Palva ET: The tobacco homologue of mammalian calreticulin is present in protein complexes in vivo. Plant Cell 7: 391-406 (1995).
60. Denecke J, Ek B, Caspers M, Sinjorgo KMC, Palva ET: Analysis of sorting signals responsible for the accumulation of soluble reticuloplasmins in the plant endoplasmic reticulum. J Exp Bot (Suppl.) 44: 213-221 (1993).
61. Denecke J, Goldman MHS, Demolder J, Seurink J, Botterman J: The tobacco luminal binding protein is encoded by a multigene family. Plant Cell 1025-1035 (1991).
62. Denecke J, Vitale A: The use of protoplasts to study protein synthesis and transport by the plant endomembrane system. In: Galbraith D, Bourque D, Bohnert D (eds) Methods in Cell Biology Part B, pp. 335-348. Academic Press, New York (1995).
63. DeRocher A, Vierling E: Cytoplasmic HSP70 homologues of pea: differential expression in vegetative and embryonic organs. Plant Mol Biol 27: 441-456 (1995).
64. DeRocher AE, Helm KW, Lauzon LM, Vierling E: Expression of a conserved family of cytoplasmic low molecular weight heat shock proteins during heat stress and recovery. Plant Physiol 96: 1038-1047 (1991).
65. Dickson R, Howard R, Alldrick SP, Ellis RJ, Viitanen PV: Reconstitution of higher plant chloroplast chaperonin 60 tetradecamers active in protein folding. J Biol Chem, submitted (1996).
66. Dickson R, Larsen B, Viitanen PV, Tormey MB, Geske J, Strange R, Bemis LT: Cloning, expression, and purification of a functional nonacetylated mammalian mitochondrial chaperonin 10. J Biol Chem 269: 26858-26864 (1994).
67. Domoney C, Ellis N, Turner L, Casey R: A developmentally regulated early-embryogenesis protein in pea (Pisum sativum L.) is related to the heat-shock protein (HSP70) gene family. Planta 184: 350-355 (1991).
68. Duck N, McCormick S, Winter J: Heat shock protein hsp70 cognate gene expression in vegetative and reproductive organs of Lycopersicon esculentum. Proc Natl Acad Sci 86: 3674-3678 (1989).
69. Dure L, III: A repeating 11-mer amino acid motif and plant desiccation. Plant J 3: 363-369 (1993).
70. Dwek RA: Glycobiology: More functions for oligosaccharides. Science 269: 1234-1235 (1995).
71. Ehmann B, Krenz M, Mummert E, Schäfer E: Two Tcp-1-related but highly divergent gene families exist in oat encoding proteins of assumed chaperone function. FEBS Lett 336: 313-316 (1993).
72. Ellis J: Protein folding: cytosolic chaperonin confirmed. Nature 358: 191-192 (1992).
73. Ellis RJ: Molecular chaperones: the plant connection. Science 250: 954-959 (1990).
74. Ellis RJ: Chaperone function: cracking the second half of the genetic code. Plant J 1: 9-13 (1991).
75. Ellis RJ, van der Vies SM: The Rubisco subunit binding protein. Photosyn Res 16: 101-115 (1988).
76. Ellis RJ, van der Vies SM: Molecular chaperones. Annu Rev Biochem 60: 321-347 (1991).
77. Engel A, Hayer-Hartl MK, Goldie KN, Pfeifer G, Hegerl R, Müller S, Da Silva ACR, Baumeister W, Hartl FU: Functional significance of symmetrical versus asymmetrical GroEL-GroES chaperonin complexes. Science 269: 832-836 (1995).
78. Fayet O, Ziegelhoffer T, Georgopoulos C: The groES and groEL heat shcok gene products of Escherichia coli are essential for bacterial growth at all temperatures. J Bact 171: 1379-1385 (1989).
79. Felsheim RF, Das A: Structure and expression of a heat-shock protein 83 gene of Pharbitis nil. Plant Physiol 100: 1764-1771 (1992).
80. Fischer HM, Babst M, Kaspar T, Acuña G, Arigoni F, Hennecke H: One member of a groESL-like chaperonin multigene family in Bradyrhizobium japonicum is co-regulated with symbiotic nitrogen fixation genes. EMBO J 12: 2901-2912 (1993).
81. Flaherty KM, DeLuca-Falherty C, McKay DB: Three-dimensional structure of the ATPase fragment of a 70K heat-shock cognate protein. Nature 346: 623-628 (1990).
82. Flaherty KM, McKay DB, Kabsch W, Holmes KC: Similarity of the three-dimensional structures of actin and the ATPase fragment of a 70- kDa heat shock cognate protein. Proc Natl Acad Sci USA 88: 5041-5045 (1991).
83. Flynn GC, Chappell TG, Rothman JE: Peptide binding and release by proteins implicated as catalysts of protein assembly. Science 245: 285-390 (1989).
84. Flynn GC, Pohl J, Flocco MT, Rothman JE: Peptide-binding specificity of the molecular chaperone BiP. Nature 353: 726-730 (1991).
85. Fontes EBP, Shank BB, Wrobel RL, Moose SP, OBrian GR, Wurtzel ET, Boston RS: Characterization of an immunoglobulin binding protein homologue in the maize floury-2 endosperm mutant. Plant Cell 3: 483-496 (1991).
86. Fourie AM, Sambrook JF, Gething M-JH: Common and divergent peptide binding specificities of hsp70 molecular chaperones. J Biol Chem 269: 30470-30478 (1994).
87. Freedman RB: Protein disulphide isomerase: multiple roles in the modification of nascent secretory proteins. Cell 57: 1069-1072 (1989).
88. Freedman RB, Hirst TR, Tuite MF: Protein disulphide isomerase: building bridges in protein folding. Trends Biochem Sci 19: 331-336 (1994).
89. Frydman J, Nimmesgern E, Erdjument-Bromage H, Wall JS, Tempst P, Hartl F-U: Function in protein folding of TRiC, a cytosolic ring complex containing TCP-1 and structurally related subunits. EMBO J 11: 4767-4778 (1992).
90. Frydman J, Nimmesgern E, Ohtsuka K, Hartl FU: Folding of nascent polypeptide chains in a high molecular mass assembly with molecular chaperones. Nature 370: 111-117 (1994).
91. Gao Y, Thomas JO, Chow RL, Lee G-H, Cowan NJ: A cytoplasmic chaperonin that catalyzes β-actin folding. Cell 69: 1043-1050 (1992).
92. Gao Y, Vainberg IE, Chow RL, Cowan NJ: Two cofactors and cytoplasmic chaperonin are required for the folding of α- and β-tubulin. Mol Cell Biol 13: 2478-2485 (1993).
93. Gasser CS, Gunning DA, Budelier KA, Brown SM: Structure and expression of cytosolic cyclophilin/peptidyl-prolyl cis-trans isomerase of higher plants and production of active tomato cyclophilin in Escherichia coli. Proc Natl Acad Sci USA 87: 9519-9523 (1990).
94. Gatenby AA: The chaperoning of photosynthetic organisms. In Ellis RJ (ed) The chapronins, Academic Press, pp. 65-90 (1996).
95. Gatenby AA, Ellis RJ: Chaperone function: the assembly of ribulose bisphosphate carboxylase-oxygenase. Annu Rev Cell Biol 6: 125-149 (1990).
96. Gatenby AA, Lubben TH, Ahlquist P, Keegstra K: Imported large subunits of ribulose bisphosphate carboxylase/oxygenase, but not imported β-ATP synthase sununits, are assembled into holoenzyme in isolated chloroplasts. EMBO J 7: 1307-1314 (1988).
97. Gatenby AA, Viitanen PV: Structural and functional aspects of chaperonin-mediated protein folding. Annu Rev Plant Physiol Plant Mol Biol 45: 469-491 (1994).
98. Geli MI, Torrent M, Ludevid D: Two structural domains mediate two sequential events in gamma-zein targeting: protein endoplasmic reticulum retention and protein body formation. Plant Cell 6: 1911-1922 (1994).
99. Georgopoulos C, Welch WJ: Role of the major heat shock proteins as molecular chaperones. Annu Rev Cell Biol 9: 601-634 (1993).
100. Gething M-J, Sambrook J: Protein folding in the cell. Nature 355: 33-45 (1992).
101. Gilbert HF: Protein chaperones and protein folding. Curr Opin Biotechnol 5: 534-539 (1994).
102. Gillikin JW, Boston RS: Plant BiPs. In: Gething MJ (ed) Guidebook to Molecular Chaperones and Protein Folding Catalysts. Sambrook and Tooze Publications at Oxford University Press, New York, in press (1996).
103. Gillikin JW, Fontes EPB, Boston RS: Protein-protein interactions in the endoplasmic reticulum. In: Galbraith D, Bourque D, Bohnert D (eds) Methods in Cell Biology Part B, pp. 309-323. Academic Press, New York (1995).
104. Goloubinoff P, Christeller JT, Gatenby AA, Lorimer GH: Reconstitution of active dimeric ribulose bisphosphate carboxylase from an unfolded state depends on two chaperonin proteins and Mg-ATP. Nature 342: 884-889 (1989).
105. Goloubinoff P, Gatenby AA, Lorimer GH: GroE heat-shock proteins promote assembly of foreign prokaryotic ribulose bisphosphate carboxylase oligomers in Escherichia coli. Nature 337: 44-47 (1989).
106. Gottesman S, Squires C, Pichersky E, Carrington M, Hobbs M, Mattick JS, Dalrymple B, Kuramitsu H, Shiroza T, Foster T, Clark WP, Ross B, Squires CL, Maurizi MR: Conservation of the regulatory subunit for the Clp ATP-dependent protease in prokaryotes and eukaryotes. Proc Natl Acad Sci 87: 3513-3517 (1990).
107. Gragerov A, Gottesman ME: Different peptide binding specificities of hsp70 family members. J Mol Biol 241: 133-135 (1994).
108. Gray JC, Row PE: Protein translocation across chloroplast envelope membranes. Trends Cell Biol 5: 243-247 (1995).
109. Gray TE, Fersht AR: Cooperativity in ATP hydrolysis by GroEL is increased by GroES. FEBS Lett 292: 254-258 (1991).
110. Grynberg A, Nicolas J, Drapron R: Some characteristics of protein disulfide isomerase (E.C. 5.3.4.1) from wheat (Triticum vulgare) embryo. Biochimie 60: 547-551 (1978).
111. Gupta RS: Phylogenetic analysis of the 90 kD heat shock family of protein sequences and an examination of the relationship among animals, plants, and fungi species. Mol Biol Evol 12: 1063-1073 (1995).
112. Gutteridge S, Gatenby AA: Rubisco synthesis, assembly, mechanism, and regulation. Plant Cell 7: 809-819 (1995).
113. Hartl FU, Martin J: Molecular chaperones in cellular protein folding. Curr Opin Struct Biol 5: 92-102 (1995).
114. Hartman DJ, Dougan D, Hoogenraad NJ, Hoj PB: Heat shock proteins of barley mitochondria and chloroplasts: Identification of organellar hsp 10 and 12: putative chaperonin 10 homologues. FEBS Lett 305: 147-150 (1992).
115. ++ storage protein in the endoplasmic reticulum of the pea plant (Pisum sativum). Biochem Biophys Res Commun 211: 54-59 (1995).
116. Hayman GT, Miernyk JA: The nucleotide and deduced amino acid sequences of a peptidyl-prolyl cis-trans isomerase from Arabidopsis thaliana. Biochim Biophys Acta 1219: 536-538 (1994).
117. Helm KW, LaFayette PR, Nagao RT, Key JL, Vierling E: Localization of small heat shock proteins to the higher plant endomembrane system. Mol Cell Biol 13: 238-247 (1993).
118. Helm KW, Schmeits J, Vierling E: An endomembrane-localized small heat-shock protein from Arabidopsis thaliana. Plant Physiol 107: 287-288 (1995).
119. Hemmingsen SM, Ellis RJ: Purification and properties of ribulosebisphosphate carboxylase large subunit binding protein. Plant Physiol 80: 269-276 (1986).
120. Hemmingsen SM, Woolford C, Van der Vies SM, Tilly K, Dennis DT, Georgopoulos CP, Hendrix R, Ellis RJ: Homologous plant and bacterial proteins chaperone oligomeric protein assembly. Nature 333: 330-334 (1988).
121. Hendrick JP, Hartl F-U: Molecular chaperone functions of heat- shock proteins. Annu Rev Biochem 62: 349-384 (1993).
122. Hendrix RW: Purification and properties of groE, a host protein involved in bacteriophage lambda assembly. J Mol Biol 129: 375-392 (1979).
123. Holdridge C, Dorsett D: Repression of hsp70 heat shock gene transcription by the suppressor of hairy-wing protein of Drosophila melanogaster. Mol Cell Biol 11: 1894-1900 (1991).
124. Horwich AL: Molecular chaperones: resurrection or destruction. Curr Biol 5: 455-458 (1995).
125. Horwich AL, Willison KR: Protein folding in the cell: functions of two families of molecular chaperone, hsp 60 and TF55-TCP1. Phil Trans R Soc Lond [Biol] 339: 313-326 (1993).
126. Horwitz J: α-Crystallin can function as a molecular chaperone. Proc Natl Acad Sci USA 89: 10449-10453 (1992).
127. Höhfeld J, Minami Y, Hartl F-U: Hip, a novel cochaperone involved in the eukaryotic Hsc70/Hsp40 reaction cycle. Cell 83: 589-598 (1995).
128. Hsieh M-H, Chen J-T, Jinn T-L, Chen Y-M, Lin C-Y: A class of soybean low molecular weight heat shock proteins. Immunological study and quantitation. Plant Physiol 99: 1279-1284 (1992).
129. Huang L, Franklin AE, Hoffman NE: Primary structure and characterization of an Arabidopsis thaliana calnexin-like protein. J Biol Chem 268: 6560-6566 (1993).
130. Hubbs A, Roy H: Synthesis and assembly of large subunits into ribulose bisphosphate carboxylase/oxygenase in chloroplast extracts. Plant Physiol 100: 272-281 (1992).
131. Hubbs AE, Roy H: Assembly of in vitro synthesized large subunits into ribulose-bisphosphate carboxylase/oxygenase: formation and discharge of an L8-like species. J Biol Chem 268: 13519-13525 (1993).
132. -, requires ATP, and does not proceed when large subunits are synthesized at temperatures >32°C. Plant Physiol 101: 523-533 (1993).
133. Hultgren SJ, Jacob-Dubuisson F, Jones CH, Bränden C-I: PapD and superfamily of periplasmic immunoglobulin-like pilus chaperones. Adv Protein Chem 44: 99-123 (1993).
134. Hutchison KA, Stancato LF, Owens-Grillo JK, Johnson JL, Krishna P, Toft DO, Pratt WB: The 23-kDa acidic protein in reticulocyte lysate is the weakly bound component of the hsp foldosome that is required for assembly of the glucocorticoid receptor into a functional heterocomplex with hsp90. J Biol Chem 270: 18841-18847 (1995).
135. Inouye M: Intramolecular chaperone: the role of the propeptide in protein folding. Enzyme 45: 314-321 (1991).
136. Jackson GS, Staniforth RA, Halsall DJ, Atkinson T, Holbrook JJ, Clarke AR, Burston SG: Binding and hydrolysis of nucleotides in the chaperonin catalytic cycle: Implications for the mechanism of assisted protein folding. Biochemistry 32: 2554-2563 (1993).
137. Jaenicke R, Creighton TE: Protein folding: Junior chaperones. Curr Biol 3: 234-235 (1993).
138. Jakob U, Buchner J: Assisting spontaneity: The role of Hsp90 and small Hsps as molecular chaperones. Trends Biochem Sci 19: 205-211 (1994).
139. Jakob U, Gaestel M, Engel K, Buchner J: Small heat shock proteins are molecular chaperones. J Biol Chem 268: 1517-1520 (1993).
140. Jakob U, Lilie H, Meyer I, Buchner J: Transient interaction of Hsp90 with early unfolding intermediates of citrate synthase. Implications for heat shock in vivo. J Biol Chem 270: 7288-7294 (1995).
141. Jakob U, Meyer I, Bügl H, André S, Bardwell JCA, Buchner J: Structural organization of procaryotic and eucaryotic Hsp90. Influence of divalent cations on structure and function. J Biol Chem 270: 14412-14419 (1995).
142. Jin Y-J, Albers MW, Lane WS, Bierer BE, Schreiber SL, Burakoff SJ: Molecular cloning of a membrane-associated human FK506- and rapamycin-binding protein, FKBP-13. Proc Natl Acad Sci USA 88: 6677-6681 (1991).
143. Jinn T-L, Chen Y-M, Lin C-Y: Chracterization and physiological function of class I low molecular weight heat shock protein complexes in soybean. Plant Physiol 108: 693-701 (1995).
144. Jinn TL, Yeh YC, Chen YM, Lin C-Y: Stabilization of soluble proteins in vitro by heat shock proteins-enriched ammonium sulfate fraction from soybean seedlings. Plant Cell Physiol 30: 463-469 (1989).
145. Jones AM, Herman EM: KDEL-containing auxin binding protein is secreted to the plasma membrane and cell wall. Plant Physiol 101: 595-606 (1993).
146. Kalinski A, Rowley DL, Loer DS, Foley C, Buta G, Herman EM: Binding-protein expression is subject to temporal, developmental and stress-induced regulation in terminally differentiated soybean organs. Planta 195: 611-621 (1995).
147. Keith B, Dong X, Ausubel FM, Fink GR: Differential induction of 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase genes in Arabidopsis thaliana by wounding and pathogenic attack. Proc Natl Acad Sci USA 88: 8821-8825 (1991).
148. Kim PS, Arvan P: Calnexin and BiP act as sequential molecular chaperones during thyroglobulin folding in the endoplasmic reticulum. J Cell Biol 128: 29-38 (1995).
149. Kim S, Willison KR, Horwich AL: Cystosolic chaperonin subunits have a conserved ATPase domain but diverged polypeptide-binding domains. Trends Biochem Sci 19: 543-548 (1994).
150. Kimura Y, Yahara I, Lindquist S: Role of the protein chaperone YDJ1 in establishing Hsp90-mediated signal transduction pathways. Science 268: 1362-1365 (1995).
151. Kirsch T, Beevers L: Uncoating of clathrin-coated vesicles by uncoating ATPase from developing peas. Plant Physiol 103: 205-212 (1993).
152. Knack G, Liu Z, Kloppstech K: Low molecular mass heat-shock proteins of a light-resistant photoautotrophic cell culture. Eur J Cell Biol 59: 166-175 (1992).
153. Knarr G, Gething MJ, Modrow S, Buchner J: BiP binding sequences in antibodies. J Biol Chem 270:27589-27594 (1995).
154. Knittler MR, Haas IG: Interaction of BiP with newly synthesized immunoglobulin light chain molecules: Cycles of sequential binding and release. EMBO J 11: 1573-1581 (1992).
155. Ko K, Bornemisza O, Kourtz L, Ko ZW, Plaxton WC, Cashmore AR: Isolation and characterization of a cDNA clone encoding a cognate 70-kDa heat shock protein of the chloroplast envelope. J Biol Chem 267: 2986-2993 (1992).
156. Koch GLE: In: Rothblatt J, Novick P, Stevens T (eds), Guidebook to the Secretory Pathway, pp. 82-83. Sambrook and Tooze Publications at Oxford University Press, New York (1994).
157. Kong TH, Coates ARM, Butcher PD, Hickman CJ, Shinnick TM: Mycobacterium tuberculosis expresses two chaperonin-60 homologues. Proc Natl Acad Sci USA 90: 2608-2612 (1993).
158. Koning AJ, Rose R, Cornai L: Developmental expression of tomato heat-shock cognate protein 80. Plant Physiol 100: 801-811 (1992).
159. Koonin EV, van der Vies SM: Conserved sequence motifs in bacterial and bacteriophage chaperonins. Trends Biochem Sci 20: 14-15 (1995).
160. Krishna P, Sacco M, Cherutti JF, Hill S: Cold-induced accumulation of hsp90 transcripts in Brassica napus. Plant Physiol 107: 915-923 (1995).
161. Kruse E, Kloppstech K: Heat shock proteins in plants: an approach to understanding the function of plastid heat shock proteins. In: Barber J (ed), The Photosystems: Structure, Function and Molecular Biology, pp. 409-442. Elsevier Sicence Publishers, Amsterdam (1992).
162. Kubota H, Hynes G, Carne A, Ashworth A, Willison K: Identification of six Tcp-1-related genes encoding divergent subunits of the TCP-1-containing chaperonin. Curr Biol 4: 89-99 (1994).
163. LaFayette PR, Nagao RT, O'Grady K, Vierling E, Key JL: Molecular characterization of cDNAs encoding low-molecular-weight heat shock proteins of soybean organelles. Plant Mol Biol 30: 159-169 (1996).
164. Laminet AA, Ziegelhoffer T, Georgopoulos C, Plückthun A: The Escherichia coli heat shock proteins GroEL and GroES modulate the folding of the β-lactamase precursor. EMBO J 9: 2315-2319 (1990).
165. Landry SJ, Gierasch LM: Polypeptide interactions with molecular chaperones and their relationship to in vivo protein folding. Annu Rev Biophys Biomol Struct 23: 645-669 (1994).
166. Landry SJ, Zeilstra-Ryalls J, Fayet O, Georgopoulos C, Gierasch LM: Characterization of a functionally important mobile domain of GroES. Nature 364: 255-258 (1993).
167. Langer T, Pfeifer G, Martin J, Baumeister W, Hartl F-U: Chaperonin-mediated protein folding: GroES binds to one end of the GroEL cylinder, which accommodates the protein substrate within its central cavity. EMBO J 11: 4757-4765 (1992).
168. Lata Singla S, Grover A: Antibodies raised against yeast HSP 104 cross-react with a heat and abscisic acid-regulated polypeptide in rice. Plant Mol Biol 22: 1177-1180 (1993).
169. Lee AS: Coordinated regulation of a set of genes by glucose and calcium ionophores in mammalian cells. Trends Biochem Sci 12: 20-23 (1987).
170. Lee GJ, Pokala N, Vierling E: Structure and in vitro molecular chaperone activity of cytosolic small heat shock proteins from pea. J Biol Chem 270: 10432-10438 (1995).
171. Lee JH, Hübel A, Schöffl F: Derepression of the activity of genetically engineered heat shock factor causes constitutive synthesis of heat shock proteins and increased thermotolerance in transgenic Arabidopsis. Plant J 8: 603-609 (1995).
172. Lee Y-RJ, Nagao RT, Key JL: A soybean 101-kD heat shock protein complements a yeast HSP104 deletion mutant in acquiring thermotolerance. Plant Cell 6: 1889-1897 (1994).
173. Lehel C, Los D, Wada H, Györgyei J, Horváth I, Kovács E, Murata N, Vigh L: A second groEL-like gene, organized in a groESL operon is present in the genome of Synechocystis sp. PCC 6803. J Biol Chem 268: 1799-1804 (1993).
174. Lenne C: Sequence and expression of the mRNA encoding HSP22, the mitochondrial small heat-shock protein in pea leaves. Biochem J 311: 805-813 (1995).
175. Lenne C, Douce R: A low molecular mass heat-shock protein is localized to higher plant mitochondria. Plant Physiol 105: 1255-1261 (1994).
176. Leonhardt SA, Fearon K, Danese PN, Mason TL: HSP78 encodes a yeast mitochondrial heat shock protein in the Clp family of ATP-dependent proteases. Mol Cell Biol 13: 6304-6313 (1993).
177. Leustek T, Amir-Shapira D, Toledo H, Brot N, Weissbach H: Autophosphorylation of 70 kDa heat shock proteins. Cell Mol Biol 38: 1-10 (1992).
178. Lewis VA, Hynes GM, Zheng D, Saibil H, Willison K: T-complex polypeptide-1 is a subunit of a heteromeric particle in the eukaryotic cytosol. Nature 358: 249-252 (1992).
179. Li C-P, Larkins BA: Expression of protein disulfide isomerase is elevated in the endosperm of the maize floury-2 mutant. Plant Mol Biol, in press (1996).
180. Li X, Henry R, Yuan J, Cline K, Hoffman NE: A chloroplast homologue of the signal recognition particle subunit SRP54 is involved in the posttranslational integration of a protein into thylakoid membranes. Proc Natl Acad Sci USA 92: 3789-3793 (1995).
181. Li X, Wu Y, Zhang D-Z, Gillikin JW, Boston RS, Franceschi VR, Okita TW: Rice prolamine protein body biogenesis: a BiP-mediated process. Science 262: 1054-1056 (1993).
182. Liberek K, Marszalek J, Ang D, Georgopoulos C, Zylicz M: Escherichia coli DnaJ and GrpE heat shock proteins jointly stimulate ATPase activity of DnaK. Proc Natl Acad Sci USA 88: 2874-2878 (1991).
183. Lin T-Y, Duck NB, Winter J, Folk WR: Sequences of two hsc 70 cDNAs from Lycopersicon esculentum. Plant Mol Biol 16: 475-478 (1991).
184. Lin X, Chern M, Zimmerman JL: Cloning and characterization of a carrot hsp70 gene. Plant Mol Biol 17: 1245-1249 (1991).
185. Lindquist S, Craig EA: The heat shock proteins. Annu Rev Genet 22: 631-677 (1988).
186. Lippuner V, Chou IT, Scott SV, Ettinger WF, Theg SM, Gasser CS: Cloning and characterization of chloroplast and cytosolic forms of cyclophilin from Arabidopsis thaliana. J Biol Chem 269: 7863-7868 (1994).
187. Lissin NM: In vitro dissociation and self-assembly of three chaperonin 60s: the role of ATP. FEBS Lett 361: 55-60 (1995).
188. Lissin NM, Venyaminov SY, Girshovich AS: (Mg-ATP)-dependent self-assembly of molecular chaperone GroEL. Nature 348: 339-342 (1990).
189. Lorimer GH: Role of accessory proteins in protein folding. Curr Biol 2: 26-34 (1992).
190. Luan S, Albers MW, Schreiber SL: Light-regulated, tissue-specific immunophilins in a higher plant. Proc Natl Acad Sci USA 91: 984-988 (1994).
191. Luan S, Lane WS, Schreiber SL: pCyP B: a chloroplast-localized, heat shock-responsive cyclophilin from fava bean. Plant Cell 6: 885-892 (1994).
192. + channels in guard cells. Proc Natl Acad Sci USA 90: 2202-2206 (1993).
193. Lubben TH, Donaldson GK, Viitanen PV, Gatenby AA: Several proteins imported into chloroplasts form stable complexes with the GroEL-related chloroplast molecular chaperone. Plant Cell 1: 1223-1230 (1989).
194. Lubben TH, Gatenby AA, Donaldson GK, Lorimer GH, Viitanen PV: Identification of a groES-like chaperonin in mitochondria that facilitates protein folding. Proc Natl Acad Sci USA 87: 7683-7687 (1990).
195. Madueno F, Napier JA, Gray JC: Rieske iron-sulfur protein associates with both cpn60 and hsp70 in the chloroplast stroma. Plant Cell 5: 1865-1876 (1993).
196. Marocco A, Santucci A, Cerioli S, Motto M, Di Fonzo N, Thompson R, Salamini F: Three high-lysine mutations control the level of ATP-binding HSP70-like proteins in the maize endosperm. Plant Cell 3: 507-515 (1991).
197. Marrs KA, Casey ES, Capitant SA, Bouchard RA, Dietrich PS, Mettler IJ, Sinibaldi RM: Characterization of two maize hsp90 heat shock protein genes: expression during heat shock, embryogenesis, and pollen development. Devel Genet 14: 27-41 (1993).
198. Marshall JS, DeRocher AE, Keegstra K, Vierling E: Identification of heat shock protein hsp70 homologues in chloroplasts. Proc Natl Acad Sci USA 87: 374-378 (1990).
199. Marshall JS, Keegstra K: Isolation and characterization of a cDNA clone encoding the major Hsp70 of the pea chloroplastic stroma. Plant Physiol 100: 1048-1054 (1992).
200. Martel R, Cloney LP, Pelcher LE, Hemmingsen SM: Unique composition of plastid chaperonin-60: α and β polypeptide-encoding genes are highly divergent. Gene 94: 181-187 (1990).
201. Martin J, Langer T, Boteva R, Schramel A, Horwich AL, Hartl F-U: Chaperonin-mediated protein folding at the surface of groEL through a 'molten globule'-like intermediate. Nature 352: 36-42 (1991).
202. Martin J, Mayhew M, Langer T, Hartl FU: The reaction cycle of GroEL and GroES in chaperonin-assisted protein folding. Nature 366: 228-233 (1993).
203. Martinus RD, Ryan MT, Naylor DJ, Herd SM, Hoogenraad NJ, Hoj PB: Role of chaperones in the biogenesis and maintenance of the mitochondrion. FASEB J 9: 371-378 (1995).
204. Matouschek A, Rospert S, Schmid K, Glick BS, Schatz G: Cyclophilin catalyzes protein folding in yeast mitochondria. Proc Natl Acad Sci USA 92: 6319-6323 (1995).
205. Melki R, Cowan NJ: Facilitated folding of actins and tubulins occurs via a nucleotide-dependent interaction between cytoplasmic chaperonin and distinctive folding intermediates. Mol Cell Biol 14: 2895-2904 (1994).
206. Melnick J, Aviel S, Argon Y: The endoplasmic reticulum stress protein GRP94, in addition to BiP, associates with unassembled immunoglobulin chains. J Biol Chem 267: 21303-21306 (1992).
207. Melnick J, Dul JL, Argon Y: Sequential interaction of the chaperones BiP and GRP94 with immunoglobulin chains in the endoplasmic reticulum. Nature 370: 373-375 (1994).
208. Menegazzi P, Guzzo F, Baldan B, Mariani P, Treves S: Purification of calreticulin-like protein(s) from spinach leaves. Biochem Biophys Res Commun 190: 1130-1135 (1993).
209. Merck KB, Groenen PJTA, Voorter CEM, de Haard-Hoekman WA, Horwitz J, Bloemendal H, de Jong WW: Structural and functional similarities of bovine α-crystallin and mouse small heat-shock protein. A family of chaperones. J Biol Chem 268: 1046-1052 (1993).
210. Miernyk JA, Duck NB, Shatters RG, Jr., Folk WR: The 70-kilodalton heat shock cognate can act as a molecular chaperone during the membrane translocation of a plant secretory protein precursor. Plant Cell 4: 821-829 (1992).
211. Miernyk JA, Hayman GT: ATPase activity and molecular chaperone function of the stress70 proteins. Plant Physiol 110: 419-424 (1996).
212. Miller SG, Leclerc RF, Erdos RF: Identification and characterization of a testis-specific isoform of a chaperonin in a moth, Heliothis virescens. J Mol Biol 214: 407-422 (1990).
213. Milos P, Roy H: ATP-released L subunits participate in the assembly of ribulose bisphosphate carboxylase. J Cell Biochem 24: 153-162 (1984).
214. Moore T, Keegstra K: Characterization of a cDNA clone encoding a chloroplast-targeted Clp homologue. Plant Mol Biol 21: 525-537 (1993).
215. Mori M, Murata K, Kubota H, Yamamoto A, Matsushiro A, Morita T: Cloning of a cDNA encoding the Tcp-1 (t complex polypeptide 1) homologue of Arabidopsis thaliana. Gene 122: 381-382 (1992).
216. Morimoto R, Tissières A, Georgopolous C: The biology of heat shock proteins and molecular chaperones. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY (1994).
217. Mummert E, Grimm R, Speth V, Eckerskorn C, Schiltz E, Gatenby AA, Schäfer E: A TCP1-related molecular chaperone from plants refolds phytochrome to its photoreversible form. Nature 363: 644-648 (1993).
218. Mummert E, Grimm R, Speth V, Eckerskorn C, Schiltz E, Gatenby AA, Schäfer E: A TCP1-related molecular chaperone from plants refolds phytochrome to its photoreversible form - Correction. Nature 372: 709 (1994).
219. Musgrove JE, Johnson RA, Ellis RJ: Dissociation of the ribulosebisphosphate-carboxylase large-subunit binding protein into dissimilar subunits. Eur J Biochem 163: 529-534 (1987).
220. Müller FW, Igloi GL, Beck CF: Structure of a gene encoding heat-shock protein HSP70 from the unicellular alga Chlamydomanas reinhardtii. Gene 111: 165-173 (1992).
221. Napier RM, Fowke LC, Hawes C, Lewis M, Pelham HRB: Immunological evidence that plants use both HDEL and KDEL for targeting proteins to the endoplasmic reticulum. J Cell Sci 102: 261-271 (1992).
222. Nathan DF, Lindquist S: Mutational analysis of Hsp90 function: interactions with a steroid receptor and a protein kinase. Mol Cell Biol 15: 3917-3925 (1995).
223. Neumann D, Emmermann M, Thierfelder JM, Nieden U, Clericus M, Braun HP, Nover L, Schmitz UK: HSP68-3 DnaK-like heat-stress protein of plant mitochondria. Planta 190: 32-43 (1993).
224. Nielsen JB, Foor F, Siekierka JJ, Hsu M-J, Ramadan N, Morin N, Shafiee A, Dahl AM, Brizuela L, Chrebet G, Bostian KA, Parent SA: Yeast FKBP-13 is a membrane-associated FK506-binding protein encoded by the nonessential gene FKB2. Proc Natl Acad Sci USA 89: 7471-7475 (1992).
225. Nieto-Sotelo J, Vierling E, Ho T-HD: Cloning, sequence analysis, and expression of a cDNA encoding a plastid-localized heat shock protein in maize. Plant Physiol 93: 1321-1328 (1990).
226. Normington K, Kohno K, Kozutsumi Y, Gething M-J, Sambrook J: S. cerevisiae encodes an essential protein homologous in sequence and function to mammalian BiP. Cell 57: 1223-1236 (1989).
227. Okita TW, Rogers JC: Compartmentation of proteins in the endomembrane system of plant cells. Annu Rev Plant Physiol Plant Mol Biol, in press (1996).
228. + but not ATP hydrolysis. Nature 365: 664-666 (1993).
229. Parker W, Wells TA, Meza-Keuthen S, Kim I-S, Song P-S: Purification and characterization of a 60-kDa protein from oat, formerly known as a TCP 1-related chaperone. J Protein Chem 14: 53-58 (1995).
230. Parsell DA, Kowal AS, Singer MA, Lindquist S: Protein disaggregation mediated by heat-shock protein Hsp104. Nature 372: 475-478 (1994).
231. Parsell DA, Lindquist S: The function of heat-shock proteins in stress tolerance: degradation and reactivation of proteins. Annu Rev Genet 27: 437-496 (1993).
232. Parsell DA, Sanchez Y, Stitzel JD, Lindquist S: Hsp104 is a highly conserved protein with two essential nucleotide-binding sites. Nature 353: 270-273 (1991).
233. Pedrazzini E, Giovinazzo G, Bollini R, Ceriotti A, Vitale A: Binding of BiP to an assembly-defective protein in plant cells. Plant J 5: 103-110 (1994).
234. Pedrazzini E, Vitale A: The binding protein,BiP, and the synthesis of secretory proteins. Plant Physiol Biochem 34: 207-216 (1996).
235. Pelham HRB: Function of the hsp70 protein family: an overview. In: Morimoto RI, Tissieres A, Georgopoulos C (eds) Stress Proteins in Biology and Medicine, pp. 287-299. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY (1990).
236. Phipps BM, Hoffmann A, Stetter KO, Baumeister W: A novel ATPase complex selectively accumulated upon heat shock is a major cellular component of thermophilic archaebacteria. EMBO J 10: 1711-1722 (1991).
237. Phipps BM, Typke D, Hegerl R, Volker S, Hoffmann A, Stetter KO, Baumeister W: Structure of a molecular chaperone from a thermophilic archaebacterium. Nature 361: 475-477 (1993).
238. Picard D, Khursheed B, Garabedian MJ, Fortin MG, Lindquist S, Yamamoto KR: Reduced levels of hsp90 compromise steroid receptor action in vivo. Nature 348: 166-168 (1990).
239. Picketts DJ, Mayanil CSK, Gupta RS: Molecular cloning of a Chinese hamster mitochondrial protein related to the 'chaperonin' family of bacterial and plant proteins. J Biol Chem 264: 12001-12008 (1989).
240. Polissi A, Goffin L, Georgopoulos C: The Escherichia coli heat shock response and bacteriophage lambda development. FEMS Microbiol Rev 17: 159-169 (1995).
241. Prasad TK, Hallberg RL: Identification and metabolic characterization of the Zea mays mitochondrial homologue of the Escherichia coli GroEL protein. Plant Mol Biol 12: 609-618 (1989).
242. Pratt WB: The role of heat shock proteins in regulating the function, folding, and trafficking of the glucocorticoid receptor. J Biol Chem 268: 21455-21458 (1993).
243. Preisig-Müller R, Kindl H: Plant dnaJ homologue: molecular cloning, bacterial expression, and expression analysis in tissues of cucumber seedlings. Arch Biochem Biophys 305: 30-37 (1993).
244. Pushkin AV, Tsuprun VL, Solovjeva NA, Shubin VV, Evstigneeva ZG, Kretovich WL: High molecular weight pea leaf protein similar to the groE protein of Escherichia coli. Biochim Biophys Acta 704: 379-384 (1982).
245. Quaite-Randall E, Trent JD, Josephs, R., Joachimiak A: Conformational cycle of the Archaeosome, a TCP1-like chaperonin from Sulfolobus shibatae. J Biol Chem 270: 28818-28823 (1995).
246. Rassow J, Voos W, Pfanner N: Partner proteins determine multiple functions of Hsp70. Trends Cell Biol 5: 207-212 (1995).
247. Reith M, Munholland J: An hsp70 homologue is encoded on the plastid genome of the red alga, Porphyra umbilicalis. FEBS Lett 294: 116-120 (1991).
248. Rippmann F, Taylor WR, Rothbard JB, Green NM: A hypothetical model for the peptide binding domain of hsp70 based on the peptide binding domain of HLA. EMBO J 10: 1053-1059 (1991).
249. Roberts JK, Key JL: Isolation and characterization of a soybean hsp70 gene. Plant Mol Biol 16: 671-683 (1991).
250. Rochester DE, Winter JA, Shah DM: The structure and expression of maize genes encoding the major heat shock proteins, hsp70. EMBO J 5: 451-458 (1986).
251. Roden LT, Miflin BJ, Freedman RB: Protein disulphide-isomerase is located in the endoplasmic reticulum of developing wheat endosperm. FEBS Lett 138: 121-124 (1982).
252. Rommelaere H, Van Troys M, Gao Y, Melki R, Cowan NJ, Vandekerckhove J, Ampe C: Eukaryotic cytosolic chaperonin contains t-complex polypeptide 1 and seven related subunits. Proc Natl Acad Sci USA 90: 11975-11979 (1993).
253. Rose MD, Misra LM, Vogel JP: KAR2, a karyogamy gene, is the yeast homologue of the mammalian BIP/GRP78 gene. Cell 57: 1211-1221 (1989).
254. Rospert S, Glick BS, Jenö P, Schatz G, Todd MJ, Lorimer GH, Viitanen PV: Identification and functional analysis of chaperonin 10, the groES homologue from yeast mitochondria. Proc Natl Acad Sci USA 90: 10967-10971 (1993).
255. Rospert S, Junne T, Glick BS, Schatz G: Cloning and disruption of the gene encoding yeast mitochondrial chaperonin 10, the homolog of E. coli groES. FEBS Lett 335: 358-360 (1993).
256. Rothblatt J, Novick P, Stevens T: Guidebook to the Secretory Pathway. Sambrook and Tooze Publications at Oxford University Press, New York (1994).
257. Rowling PJE: Folding, assembly and posttranslational modification of proteins within the lumen of the endoplasmic reticulum. Subcell Biochem 21: 41-80 (1993).
258. Roy H: Rubisco assembly: a model system for studying the mechanism of chaperonin action. Plant Cell 1: 1035-1042 (1989).
259. Roy H, Bloom M, Milos P, Monroe M: Studies on the assembly of large subunits of ribulose bisphosphate carboxylase in isolated pea chloroplasts. J Cell Biol 94: 20-27 (1982).
260. Roy H, Hubbs A, Cannon S: Stability and dissociation of the large subunit of RuBisCo binding protein complexes in vitro and in organello. Plant Physiol 86: 50-53 (1988).
261. Rutherford SL, Zuker CS: Protein folding and the regulation of signaling pathways. Cell 79: 1129-1132 (1994).
262. Saibil HR, Zheng D, Roseman AM, Hunter AS, Watson GMF, Chen S, Auf der Mauer A, O'Hara BP, Wood SP, Mann NH, Barnett LK, Ellis RJ: ATP induces large quaternary rearrangements in a cage-like chaperonin structure. Curr Biol 3: 265-273 (1993).
263. Sanchez Y, and Lindquist SL: HSP104 required for induced thermotolerance. Science 248: 1112-1115 (1990).
264. Sanchez Y, Taulien J, Borkovich KA, Lindquist S: Hsp104 is required for tolerance to many forms of stress. EMBO J 11: 2357-2364 (1992).
265. Sanders SL, Whitfield KM, Vogel JP, Rose MD, Schekman RW: Sec61p and BiP directly facilitate polypeptide translocation into the ER. Cell 69: 353-365 (1992).
266. Scaramuzzi CD, Stokes HW, Hiller RG: Heat shock Hsp70 protein is chloroplast-encoded in the chromophytic alga Pavlova lutherii. Plant Mol Biol 18: 467-476 (1992).
267. Schaller A, Ryan CA: Cloning of a tomato cDNA (Gen-Bank L388581) encoding the proteolytic subunit of a Clp-like energy dependent proteolysis. Plant Physiol 108: 1341(1995).
268. Schirmer EC, Lindquist S, Vierling E: An Arabidopsis heat shock protein complements a thermotolerance defect in yeast. Plant Cell 6: 1899-1909 (1994).
269. Schirmer EC, Lindquist SL: The HSP100 family. In: Gething MJ (ed), Guidebook to Molecular Chaperones and Protein Folding Catalysts. Oxford University Press, in press (1966).
270. Schmid FX, Mayr LM, Mucke M, Schonbrunner ER: Prolyl isomerases: role in protein folding. Adv Protein Chem 44: 25-66 (1993).
271. Schmidt M, Buchner J, Todd MJ, Lorimer GH, Viitanen PV: On the role of groES in the chaperonin-assisted folding reaction. Three case studies. J Biol Chem 269: 10304-10311 (1994).
272. Schmidt M, Rutkat K, Rachel R, Pfeifer G, Jaenicke R, Viitanen P, Lorimer G, Buchner J: Symmetric complexes of GroE chaperonins as part of the functional cycle. Science 265: 656-659 (1994).
273. Schmitt M, Neupert W, Langer T: Hsp78, a Clp homologue within mitochondria, can substitute for chaperone functions of mt-hsp70. EMBO J 14: 3434-3444 (1995).
274. Schnell DJ, Kessler F, Blobel G: Isolation of components of the chloroplast protein import machinery. Science 266: 1007-1012 (1994).
275. Schreiber SL: Chemistry and biology of the immunophilins and their immunosuppressive ligands. Science 251: 283-287 (1991).
276. Schroder G, Beck M, Eichel J, Vetter H, Schroder J: HSP90 homologue from Madagascar periwinkle (Catharanthus roseus): cDNA sequence, regulation of protein expression and location in the endoplasmic reticulum. Plant Mol Biol 23: 583-598 (1993).
277. Shanklin J, DeWitt ND, Flanagan JM: The stroma of higher plant plastids contain ClpP and ClpC, functional homologues of E. coli ClpP and ClpA: a two component ATP-dependent protease. Plant Cell 7: 1713-1722 (1995).
278. Shimoni Y, Segal G, Zhu X, Galili G: Nucleotide sequence of a wheat cDNA encoding protein disuphide isomerase. Plant Physiol 107: 281(1995).
279. Shorrosh BS, Dixon RA: Molecular cloning of a putative plant endomembrane protein resembling vertebrate protein disulfide-isomerase and a phosphatidylinositol-specific phospholipase C. Proc Natl Acad Sci USA 88: 10941-10945 (1991).
280. Shorrosh BS, Dixon RA: Molecular characterization and expression of an alfalfa protein with sequence similarity to mammalian ERp72, a glucose-regulated endoplasmic reticulum protein containing active site sequences of protein disphide isomerase. Plant J 2: 51-58 (1992).
281. Shorrosh BS, Subramaniam J, Schubert KR, Dixon RA: Expression and localization of plant protein disulfide isomerase. Plant Physiol 103: 719-726 (1993).
282. Silver PA, Way JC: Eukaryotic dnaJ homologues and the specificity of Hsp70 activity. Cell 74: 5-6 (1993).
283. Simons JF, Ferro-Novick S, Rose MD, Helenius A: BiP/Kar2p serves as a molecular chaperone during carboxypeptidase Y folding in yeast. J Cell Biol 130: 41-49 (1995).
284. Squires C, Squires CL: The Clp proteins: proteolysis regulators or molecular chaperones. J Bact 174: 1081-1085 (1992).
285. Strsalka K, Tsugeki R, Nishimura M: Heat shock induces synthesis of plastid-associated hsp70 in etiolated and greening pumpkin seedlings. Fol Histochem Cytobiol 32: 45-49 (1994).
286. Stuart RA, Cyr DM, Craig EA, Neupert W: Mitochondrial molecular chaperones: their role in protein translocation. Trends Biochem Sci 19: 87-92 (1994).
287. Takahashi T, Naito S, Komeda Y: Isolation and analysis of the expression of two genes for the 81-kilodalton heat-shock proteins from Arabidopsis. Plant Physiol 99: 383-390 (1992).
288. Takenaka IM, Hightower LE: Transforming growth factor-β1 rapidly induces Hsp70 and Hsp90 molecular chaperones in cultured chicken embryo cells. J Cell Physiol 152: 568-577 (1992).
289. Todd MJ, Viitanen PV, Lorimer GH: Hydrolysis of adenosine 5′-triphosphate by Escherichia coli GroEL: Effects of GroES and potassium ion. Biochemistry 32: 8560-8567 (1993).
290. Todd MJ, Viitanen PV, Lorimer GH: Dynamics of the chaperonin ATPase cycle: implications for facilitated protein folding. Science 265: 659-666 (1994).
291. Tsugeki R, Mori H, Nishimura M: Purification, cDNA cloning and Northern-blot analysis of mitochondrial chaperonin 60 from pumpkin cotyledons. Eur J Biochem 209: 453-458 (1992).
292. + reductase upon its import into chloroplasts. FEBS Lett 320: 198-202 (1993).
293. Tsuprun VL, Boekema FJ, Samsonidze TG, Pushkin A: Electron microscopy of the complexes of ribulose-1,5-bisphosphate carboxylase (Rubisco) and Rubisco subunit-binding protein from pea leaves. FEBS Lett 289: 205-209 (1991).
294. Ursic D, Culbertson MR: The yeast homologue to mouse Tcp-1 affects microtubule-mediated processes. Mol Cell Biol 11: 2629-2640 (1991).
295. Van Berkel J, Salamini F, Gebhardt C: Transcripts accumulating during cold storage of potato (Solanum tuberosum L.) tubers are sequence related to stress-responsive genes. Plant Physiol 104: 445-452 (1994).
296. van der Vies SM, Gatenby AA, Georgopoulos C: Bacteriophage T4 encodes a co-chaperonin that can substitute for Escherichia coli GroES in protein folding. Nature 368: 654-656 (1994).
297. Viitanen PV, Gatenby AA, Lorimer GH: Purified chaperonin 60 (groEL) interacts with the nonnative states of a multitude of Escherichia coli proteins. Protein Sci 1: 363-369 (1992).
298. Viitanen PV, Lorimer GH, Seetharam R, Gupta RS, Oppenheim J, Thomas JO, Cowan NJ: Mammalian mitochondrial chaperonin 60 functions as a single toroidal ring. J Biol Chem 267: 695-698 (1992).
299. + dependent. Biochemistry 29: 5665-5671 (1990).
300. Viitanen PV, Schmidt M, Buchner J, Suzuki T, Vierling E, Dickson R, Lorimer GH, Gatenby A, Soll J: Functional characterization of the higher plant chloroplast chaperonins. J Biol Chem 270: 18158-18164 (1995).
301. Vinh DB-N, Drubin DG: A yeast TCP-1-like protein is required for actin function in vivo. Proc Natl Acad Sci USA 91: 9116-9120 (1994).
302. Vitale A, Bielli A, Ceriotti A: The binding protein associates with monomeric phaseolin. Plant Physiol 107: 1411-1418 (1996).
303. Vitale A, Ceriotti A, Denecke J: The role of the endoplasmic reticulum in protein synthesis, modification and intracellular transport. J Exp Bot 44: 1417-1444 (1993).
304. Vogel JL, Parsell DA, Lindquist S: Heat-shock proteins Hsp104 and Hsp70 reactivate mRNA splicing after heat inactivation. Curr Biol 5: 306-317 (1995).
305. Vogel JP, Misra LM, Rose MD: Loss of BiP/GRP78 function blocks translocation of secretory proteins in yeast. J Cell Biol 110: 1885-1895 (1990).
306. Von Stedingk EM, Glaser E: The molecular chaperone mhsp72 is partially associated with the inner mitochondrial membrane both in normal and heat stressed Spinacia oleracea. Biochem Mol Biol Int 35: 1307-1314 (1995).
307. Voordouw G, van der Vies SM, Bouwmeister PP: Dissociation of ribulose-1,5-bisphosphate carboxylased oxygenase from spinach by urea. Eur J Biochem 141: 313-318 (1984).
308. Waegemann K, Soll J: Characterization of the protein import apparatus in isolated outer envelopes of chloroplasts. Plant J 1: 149-158 (1991).
309. Waldmann T, Nimmesgern E, Nitsch M, Peters J, Pfeifer G, Müller S, Kellermann J, Engel A, Hartl F-U, Baumeister W: The thermosome of Thermoplasma acidophilum and its relationship to the eukaryotic chaperonin TRiC. Eur J Biochem 227: 848-856 (1995).
310. Walsh CT, Zydowsky LD, McKeon FD: Cyclosporin A, the cyclophilin class of peptidylprolyl isomerases, and blockade of T cell signal transduction. J Biol Chem 267: 13115-13118 (1992).
311. Walther-Larsen H, Brandt J, Collinge DB, Thordal-Christensen H: A pathogen-induced gene of barley encodes a HSP90 homologue showing striking similarity to vertebrate forms resident in the endoplasmic reticulum. Plant Mol Biol 21: 1097-1108 (1993).
312. Wang C, Lin B-L: The disappearance of an hsc70 species in mung bean seed during germination: purification and characterization of the protein. Plant Mol Biol 21: 317-329 (1993).
313. Wang H, Goffreda M, Leustek T: Characteristics of an Hsp70 homologue localized in higher plant chloroplasts that is similar to DnaK, the Hsp70 of prokaryotes. Plant Physiol 102: 843-850 (1993).
314. Wang S, Liu X-Q: The plastid genome of Cryptomonas Phi encodes an hsp70-like protein, a histone-like protein, and an acyl carrier protein. Proc Natl Acad Sci USA 88: 10783-10787 (1991).
315. Wang TF, Chang J, Wang C: Identification of the peptide binding domain of Hsc70. J Biol Chem 268: 26049-26051 (1993).
316. Waters E: The molecular evolution of the small heat shock proteins in plants. Genetics 141: 785-795 (1995).
317. Waters ER, Lee GJ, Vierling E: Evolution, structure and function of the small heat shock proteins in plants. J Exp Bot 47: 325-338 (1996).
318. Watts FZ, Walters AJ, Moore AL: Characterisation of PHSP1, a cDNA encoding a mitochondrial HSP70 from Pisum sativum. Plant Mol Biol 18: 23-32 (1992).
319. Wawrzynow A, Wojtkowiak D, Marszalek J, Banecki B, Jonsen M, Graves B, Georgopoulos C, Zylicz M: The ClpX heat-shock protein of Escherichia coli, the ATP-dependent substrate specificity component of the ClpP-ClpX protease, is a novel molecular chaperone. EMBO J 14: 1867-1877 (1995).
320. Weissman JS, Kashi Y, Fenton WA, Horwich AL: GroEL-mediated protein folding proceeds by multiple rounds of binding and release of nonnative forms. Cell 78: 693-702 (1994).
321. Wiest DL, Burgess WH, McKean D, Kearse KP, Singer A: The molecular chaperone calnexin is expressed on the surface of immature thymocytes in association with clonotype-independent CD3 complexes. EMBO J 14: 3425-3433 (1995).
322. Welch WJ, Feramisco JR: Rapid purification of mammalian 70,000-dalton stress proteins: affinity of the proteins for nucleotides. Mol Cell Biol 5: 1229-1237 (1985).
323. Weng J, Wang Z-F, Nguyen HT: Nucleotide sequence of a Triticum aestivum cDNA clone which is homologous to the 26 kDa chloroplast-localized heat shock protein gene of maize. Plant Mol Biol 17: 255-258 (1991).
324. v-src heteroprotein complex formation by benzoquinone ansamycins: essential role for stress proteins in oncogenic transformation. Proc Natl Acad Sci USA 91: 8324-8328 (1994).
325. Wiech H, Buchner J, Zimmermann R, Jakob U: Hsp90 chaperones protein folding in vitro. Nature 358: 169-170 (1992).
326. Wilbanks SM, DeLuca-Flaherty C, McKay DB: Structural basis of the 70-kilodalton heat shock cognate protein ATP hydrolytic activity. J Biol Chem 269: 12893-12898 (1994).
327. Williams DB: Calnexin: a molecular chaperone with a taste for carbohydrate. Biochem Cell Biol 73: 123-132 (1995).
328. Willison KR, Kubota H: The structure, function, and genetics of the chaperonin containing TCP-1 (CCT) in eukaryotic cytosol. In: Morimoto RI, Tissières A, Georgopoulos C (eds) The Biology of Heat Shock Proteins and Molecular Chaperones, pp. 299-312. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY (1994).
329. 2 stress. Mol Gen Genet 211: 215-319 (1988).
330. Wojtkowiak D, Georgopoulos C, Zylicz M: Isolation and characterization of ClpX, a new ATP-dependent specificity component of the Clp protease of Escherichia coli. J Biol Chem 268: 22609-22617 (1993).
331. Wolfe KH, Morden CW, Palmer JD: Function and evolution of a minimal plastid genome from a nonphotosynthetic parasitic plant. Proc Natl Acad Sci USA 89: 10648-10652 (1992).
332. Woo KM, Kim KI, Goldberg AL, Ha DB, Chung CH: The heat-shock protein ClpB in Escherichia coli is a protein-activated ATPase. J Biol Chem 267: 20429-20434 (1992).
333. Wu CH, Casper T, Browse J, Lindquist S, Somerville C: Characterization of an HSP70 cognate gene family in Arabidopsis. Plant Physiol 88: 731-740 (1988).
334. v-src kinase. Proc Natl Acad Sci USA 90: 7074-7078 (1993).
335. Yabe N, Takahashi T, Komeda Y: Analysis of tissue-specific expression of Arabidopsis thaliana HSP90-family gene HSP81. Plant Cell Physiol 35: 1207-1219 (1994).
336. Yaffe MB, Farr GW, Miklos D, Horwich AL, Sternlicht ML, Sternlicht H: TCP1 complex is a molecular chaperone in tubulin biogenesis. Nature 358: 245-248 (1992).
337. Yalovsky S, Paulsen H, Michaeli D, Chitnis PR, Nechushtai R: Involvement of a chloroplast HSP70 heat shock protein in the integration of a protein (light-harvesting complex protein precursor) into the thylakoid membrane. Proc Natl Acad Sci USA 89: 5616-5619 (1992).
338. Yuan J, Henry R, Cline K: Stromal factor plays an essential role in protein integration into thylakoids that cannot be replaced by unfolding or by heat shock protein Hsp70. Proc Natl Acad Sci USA 90: 8552-8556 (1993).
339. Zabaleta E, Oropeza A, Assad N, Mandel A, Salerno G, Herrera- Estrella L: Antisense expression of chaperonin 60β in transgenic tobacco plants leads to abnormal phenotypes and altered distribution of photoassimilates. Plant J 6: 425-432 (1994).
340. Zhang F, Boston RS: Increases in binding protein (BiP) accompany changes in protein body morphology in three high lysine mutants of maize. Protoplasma 171: 142-152 (1992).
341. Zhou R, Kroczynska B, Hayman GT, Miernyk JA: AtJ2, an arabidopsis homologue of Escherichia coli dnaJ. Plant Physiol 108: 821-822 (1995).
342. Zhou R, Miernyk JA: ATPase activities of the maize stress70 molecular chaperone proteins. J Biol Chem, in press (1996).
343. Zhu J-K, Shi J, Bressan RA, Hasegawa PM: Expression of an Atriplex nummularia gene encoding a protein homologous to the bacterial molecular chaperone DnaJ. Plant Cell 5: 341-349 (1993).