NGF but not NT-3 or BDNF prevents the A fiber sprouting into lamina II of the spinal cord that occurs following axotomy

Molecular and Cellular Neurosciences

Volumn 8, Issue 4, 1996, Pages 211-220

  Bennett, David L H ^a   French, Josephine ^a   Priestley, John V ^a   McMahon, Stephen B ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

AFFERENT NERVE GROUP 1; ANIMAL EXPERIMENT; ARTICLE; GROWTH REGULATION; MALE; NERVE CELL NETWORK; NERVE FIBER GROWTH; NERVE FIBER TRANSECTION; NOCICEPTION; NONHUMAN; PRIORITY JOURNAL; RAT; SCIATIC NERVE; SPINAL CORD;

EID: 0030267280     PISSN: 10447431     EISSN: None     Source Type: Journal    
DOI: 10.1006/mcne.1996.0059     Document Type: Article

References (37)

1. Arvidsson, J., Ygge, J., and Grant, G. (1986). Cell loss in lumbar dorsal root ganglia and transganglionic degeneration after sciatic nerve resection in the rat. Brain Res. 373: 15-21.
2. Averill, S., McMahon, S. B., Clary, D. O., Reichardt, L. F., and Priestley, J. V. (1995). Immunocytochemical localization of trkA receptors in chemically identified subgroups of adult rat sensory neurons. Eur. J. Neurosci. 7: 1484-1494.
3. Bennett, D. L. H., French, J. S., Priestley, J. V., and McMahon, S. B. (1996). The effects of BDNF on c-fos and NOS expression in dorsal horn neurones of the adult rat spinal cord. Soc. Neurosci. Abstracts 22: 396.15.
4. Bennett, G. J. (1994) Neuropathic pain. In Textbook of Pain (P. D. Wall and R. Melzack, Eds.), pp. 201-204. Churchill, Livingstone.
5. Campbell, J. N., Raja, S. N., Meyer, R. A., and McKinnon S. E. (1988) Myelinated afferents signal the hyperalgesia associated with nerve injury. Pain 32: 89-94.
6. Castro-Lopes, J. M., Coimbra, A., Grant, G., and Arvidsson, J. (1990) Ultrastructural changes of the central scalloped (C) primary afferent terminal endings of synaptic glomeruli in the substantia gelatinosa Rolandi of the rat after peripheral neurotomy. J. Neurocytol. 19: 329-337.
7. Coggeshall, R. E., Lekan, H. A., Doubell, T. J. and Woolf, C. J. (1995) Loss of unmyelinated sensory axons following peripheral nerve section in adult rats. Soc. Neurosci. Abstracts 21: 232.7.
8. Csillik, B., Schwab, M. E., and Thoenen, H. (1985) Transganglionic regulation of central terminals of dorsal root ganglion cells by nerve growth factor (NGF). Brain Res. 331: 11-15.
9. Kajander, K. C., and Xu, J. Y. (1995). Quantitative-evaluation of calcitonin-gene-related peptide and substance-P levels in rat spinal-cord following peripheral-nerve injury. Neurosci. Lett. 186: 184-188.
10. Knyihar-Csillik, E., Rakic, P., and Csillik, B. (1987) Transganglionic degenerative atrophy in the substantia gelatinosa of the spinal cord after peripheral nerve section in rhesus monkeys. Cell. Tissue. Res. 247: 599-604.
11. Koerber, H. R., Mirnics, K., Brown, P. B., and Mendell, L. M. (1994) Central sprouting and functional plasticity of regenerated primary afferents. J. Neurosci. 14: 3655-3671.
12. Lekan, H. A., Carlton, S. M., and Coggeshall, R. E. (1996) Sprouting of Aβ fibres into lamina II of the rat dorsal horn in peripheral neuropathy. Neurosci. Lett. 208: 147-150.
13. Light, A. R., and Perl, E. R. (1979) Spinal terminations of functionally identified primary afferent neurons with slowly conducting myelinated fibres. J. Comp. Neurol. 186: 133-150.
14. Mannion, R. J., Doubell, T. P., Coggeshall, R. E., and Woolf, C. J. (1996) Collateral sprouting of uninjured primary afferent A-fibers into the superficial dorsal horn of the adult rat spinal cord after topical capsaicin treatment to the sciatic nerve. J. Neurosci. 16: 5189-5195.
15. Messersmith, E. K., Leonardo, E. D., Shatz, C. J., Tessier, L. M., Goodman, C. S., and Kolodkin, A. L. (1995) Semaphorin III can function as a selective chemorepellent to pattern sensory projections in the spinal cord. Neuron 14: 949-959.
16. McMahon, S. B. (1996) NGF as a mediator of inflammatory pain. Phil. Trans. R. Soc. London Ser. B 351: 431-440.
17. McMahon, S. B., Armanini, M. P., Ling, L. H., and Phillips, H. S. (1994) Expression and coexpression of trk receptors in subpopulations of adult primary sensory neurons projecting to identified peripheral targets. Neuron 12: 1161-1171.
18. McMahon, S. B., and Kett-White, R. (1991). Sprouting of peripherally regenerating primary sensory neurones in the adult central nervous system. J. Comp. Neurol. 304: 307-315.
19. Priestley, J. V., Michael, G. J., Averill, S., Nitkunan, A., Wotherspoon, G., Rattray, M., Bennett, D. L. H., Yan, Q., and McMahon, S. B. (1996) NGF treatment increases BDNF expression in trk A immunoreactive dorsal root ganglion cells and in their central terminations within the spinal cord. Soc. Neurosci. Abstracts 22: 223.8.
20. Raivich, G., Hellweg, R., and Kreutzberg, G. W. (1991) NGF receptor mediated reduction in axonal NGF uptake and retrograde transport following sciatic-nerve injury and during regeneration. Neuron 7: 151-164.
21. Rich, K. M., Luszczynski, J. R., Osborne, P. A., and Johnson, E. M. (1987) Nerve growth factor protects adult sensory neurons from cell death and atrophy caused by nerve injury. J. Neurocytol. 16:261-268.
22. Robertson, B., Perry, M. J., and Lawson, S. N. (1991) Populations of rat spinal primary afferent neurons with choleragenoid binding compared with those labelled by markers for neurofilament and carbohydrate groups: A quantitative immunocytochemical study.J. Neurocytol. 20: 387-395.
23. Rose, R. D., and Rohlich, D. (1987) Counting sectioned cells via mathematical reconstruction. J. Comp. Neurol. 263:365-386.
24. Shortland, P., and Woolf, C. J. (1993) Chronic peripheral nerve section results in a rearrangement of the central axonal arborizations of axotomized A beta primary afferent neurons in the rat spinal cord. J. Comp. Neurol. 330:65-82.
25. Shortland, P., Woolf, C. J., and Fitzgerald, M. (1989) Morphology and somatotopic organisation of the central terminals of hind limb hair follicle afferents in the rat lumbar spinal cord. J. Comp. Neurol. 289: 416-433.
26. Sugiura, Y., Lee, C. L., and Perl, E. R. (1986). Central projections of functionally identified, unmyelinated (C) afferent fibres innervating mammalian skin. Science 234: 358-361.
27. Valtschanoff, J. G., Weinberg, R. J., and Rustioni, A. (1992) Peripheral injury and anterograde transport of wheat germ agglutinin-horseradish peroxidase to the spinal cord. Neuroscience 50: 685-696.
28. Verge, V. M. K., Gratto, K. A., Karchewski, L. A., and Richardson, P. M. (1996) Neurotrophins and nerve injury in the adult. Phil. Trans. R. Soc. London Ser. B 351: 423-430.
29. Willis, W. D., and Coggeshall, R. E. (1991) Sensory Mechanisms of the Spinal Cord. Plenum, New York.
30. Woolf, C. J. (1996) Phenotypic modification of primary sensory neurons - The role of nerve growth-factor in the production of persistent pain. Phil. Trans. R. Soc. London Ser. B 351: 441-448.
31. Woolf, C. J., Reynolds, M. L., Molander, C., O'Brien, C., Lindsay, R. M., and Benowitz, L. I. (1990) The growth-associated protein GAP-43 appears in dorsal root ganglion cells and in the dorsal horn of the rat spinal cord following peripheral nerve injury. Neuroscience 34: 465-478.
32. Woolf, C. J., Shortland, P., and Coggeshall, R. E. (1992) Peripheral nerve injury triggers central sprouting of myelinated afferents. Nature 355: 75-78.
33. Woolf, C. J., Shortland, P., Reynolds, M., Ridings, J., Doubel, T., and Coggeshall, R. E. (1995) Reorganisation of central terminals of myelinated afferents in the rat dorsal horn following peripheral axotomy. J. Comp. Neurol. 360: 121-134.
34. Yan, Q., Matheson, C., Sun, J., Radeke, M. J., Feinstein, S. C., and Miller, J. A. (1994). Distribution of intracerebral ventricularly administered neurotrophins in rat-brain and its correlation with trk receptor expression. Exp. Neurol. 127: 23-36.
35. Yan, Q., Rosenfeld, R. D., Matheson, C. R., Hawkins, N., Lopez, O. T., Bennett, L., and Welcher, A. A. (1996) Expression of brain-derived neurotrophic factor (BDNF) protein in the adult rat central nervous system. Neuroscience, in press.
36. Yip, H. K., and Johnson, E. M. (1984) Developing dorsal root ganglion neurons require trophic support from their central processes: Evidence for a role of retrogradely transported nerve growth factor from the central nervous system to the periphery. Proc. Natl. Acad. Sci. USA 81: 6245-6249.
37. Zhang, X., Bean, A. J., Wiesenfeld-Hallin, Z., Xu, X. J., and Hökfelt, T. (1995) Ultrastructural studies on peptides in the dorsal horn of the rat spinal cord. III. Effects of peripheral axotomy with special reference to galanin. Neuroscience 64: 893-915.