The porcine skeletal muscle ryanodine receptor gene structure coding region 1 to 10614 harbouring 71 exons

Animal Genetics

Volumn 27, Issue 5, 1996, Pages 297-304

  Wen, G ^a   Leeb, T ^a   Reinhart, B ^a   Schmoelzl, S ^b   Brenig, B ^a  

^a UNIVERSITY OF GÖTTINGEN   (Germany)

^b UNIVERSITY OF GUELPH   (Canada)

Author keywords

chr. 6q12; Genomic organization; Malignant hyperthermia; Porcine genome mapping; Porcine skeletal muscle ryanodine receptor gene

Indexed keywords

CALCIUM CHANNEL; MUSCLE PROTEIN; RYANODINE RECEPTOR;

AMINO ACID SEQUENCE; ANIMAL; ARTICLE; EXON; GENETICS; METABOLISM; MOLECULAR CLONING; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; OPEN READING FRAME; RESTRICTION MAPPING; SKELETAL MUSCLE; SWINE;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; CALCIUM CHANNELS; CLONING, MOLECULAR; EXONS; MOLECULAR SEQUENCE DATA; MUSCLE PROTEINS; MUSCLE, SKELETAL; OPEN READING FRAMES; RESTRICTION MAPPING; RYANODINE RECEPTOR CALCIUM RELEASE CHANNEL; SWINE;

ANIMALIA; SUIDAE; SUS SCROFA;

EID: 0030266702     PISSN: 02689146     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1365-2052.1996.tb00973.x     Document Type: Article

References (27)

1. Alexander L.J., Rohrer G.A., Stone R.T. & Beattie C.W. (1995) Porcine SINE-associated microsatellite markers: Evidence for new artiodactyl SINEs. Mammalian Genome 6, 464-8.
2. Ausubel F.M., Brent R., Kingston R.E. et al. (1995) Current Protocols in Molecular Biology. John Wiley and Sons, New York.
3. Bains W. (1986) The multiple origins of human Alu sequences. Journal of Molecular Evolution 23, 189-99.
4. Bolt R., Vögeli P. & Fries R. (1994) A polymorphic microsatellite at the RYR1 locus in swine. Animal Genetics 25 (Suppl. 1), 49-66.
5. Brenig B. & Brem G. (1990) Genomic organization and analysis of the 5′ end of the porcine ryanodine receptor gene (ryr1). FEBS Letters 298. 277-279.
6. Fill M., Ma J.J., Knudson C.M., Imagawa T., Campbell K.P. & Coronado R. (1989) Role of the ryanodine receptor of skeletal muscle in excitation-contraction coupling. Annals of the New York Academy of Science 560, 155-62.
7. 2+ release channels in malignant hyperthermia skeletal muscle. Biophysical Journal 57, 471-5.
8. Frengen E., Thomsen P., Kristensen T.. Kran S., Miller R. & Davies W. (1991) Porcine SINEs: Characterization and use in species-specific amplification. Genomics 10, 949-6.
9. Fujii J., Otsu K., Zorzato F. et al. (1991) Identification of a mutation in porcine ryanodine receptor associated with malignant hyperthermia. Science 253, 448-51.
10. Futatsugi A., Kuwajima G. & Mikoshiba K. (1995) Tissue-specific and developmentally regulated alternative splicing in mouse skeletal muscle ryanodine receptor mRNA. Biochemical Journal 305, 373-8.
11. Harbitz I., Kristensen T., Bosnes M., Kran S. & Davies W. (1992) DNA sequence of the skeletal muscle calcium release channel cDNA and verification of the Arg615-Cys615 mutation, associated with the porcine malignant hyperthermia, in Norwegian landrace pigs. Animal Genetics 23, 395-402.
12. 2+-release channels in planar bilayers. Proceedings of the National Academy of Science of the USA 85, 441-5.
13. 2+-permeable pore of the calcium release channel. Journal of Biological Chemistry 262, 16636-43.
14. Lai F.A. & Meissner G. (1990) Structure of the calcium release channel of the skeletal muscle sarcoplasmic reticulum and its regulation by calcium. Advances in Experimental Medicine and Biology 269, 73-7.
15. Ledbetter M.W., Preiner J.K., Louis C.F. & Mickelson J.R. (1994) Tissue distribution of ryanodine receptor isoforms and alleles determined by reverse transcription polymerase chain reaction. Journal of Biological Chemistry 269, 31544-51.
16. Leeb T., Schmoelzl S., Brem G. & Brenig B. (1993) Genomic organization of the porcine skeletal muscle ryanodine receptor gene (RYR1) coding region 4626 to 7929. Genomics 18, 349-54.
17. Mickelson J.R., Gallant E.M., Litterer L.A., Johnson K.M., Rempel W.E. & Louis C.F. (1988) Abnormal sarcoplasmic reticulum ryanodine receptor in malignant hyperthermia. Journal of Biological Chemistry 263, 9310-15.
18. Otsu K., Khanna V.K., Archibald A.L. & MacLennan D.H. (1991) Cosegregation of porcine malignant hyperthermia and a probable causal mutation in the skeletal muscle ryanodine receptor gene in backcross families. Genomics 11, 744-50.
19. Otsu K., Phillips M.S., Khanna V.K. & MacLennan D.H. (1992) Refinement of diagnostic assays for a probable causal mutation for porcine and human malignant hyperthermia. Genomics 13, 835-37.
20. Oyamada H., Murayama T., Takagi T. et al. (1994) Primary structure and distribution of the ryanodine-binding protein isoforms of the bullfrog skeletal muscle. Journal of Biological Chemistry 269, 17206-14.
21. Rouquier S., Giorgi D., Trask B. et al. (1993) A cosmid and yeast artificial chromosome contig containing the complete ryanodine receptor (RYR1) gene. Genomics 17, 330-40.
22. Rouquier S., Batzer M.A. & Giorgi D. (1994) Application of bacterial artificial chromosomes to the generation of contiguous physical maps: A pilot study of the human ryanodine receptor gene (RYR1) region. Analytical Biochemistry 217, 205-9.
23. Takeshima H., Nishimura S., Matsumoto T. et al. (1989) Primary structure and expression from complementary DNA of skeletal muscle ryanodine receptor. Nature 339, 439-45.
24. Takeshima H., Nishi M., Iwabe N. et al. (1994) Isolation and characterization of a gene for ryanodine receptor/calcium release channel in Drosophila melanogaster. FEBS letters 337, 81-7.
25. Thomsen P.D. & Miller J.R. (1996) Pig genome analysis: Differential distribution of SINE and LINE sequences is less pronounced than in human and mouse genomes. Mammalian Genome 7, 42-6.
26. 2+-release channel (ryanodine receptor) of skeletal muscle sarcoplasmic reticulum. Journal of Biological Chemistry 265, 2244-56.
27. Zorzato F., Sacchetto R. & Margreth A. (1994) Identification of two ryanodine receptor transcripts in neonatal, slow-, and fast-twitch rabbit skeletal muscles. Biochemical and Biophysical Research Communications 203, 1725-30.