Zinc Enhances Lipopolysaccharide-Induced Monokine Secretion by Alteration of Fluidity State of Lipopolysaccharide

Journal of Immunology

Volumn 157, Issue 7, 1996, Pages 3139-3145

  Wellinghausen, Nele ^a   Schromm, Andra B ^b   Seydel, Ulrich ^b   Brandenburg, Klaus ^b   Luhm, Jürgen ^a   Kirchner, Holger ^a   Rink, Lothar ^a  

^a UNIVERSITY OF LÜBECK   (Germany)

^b RESEARCH CENTER BORSTEL   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

DIVALENT CATION; IMMUNOLOGICAL ADJUVANT; INTERLEUKIN 1; LIPOPOLYSACCHARIDE; PHORBOL 13 ACETATE 12 MYRISTATE; TUMOR NECROSIS FACTOR ALPHA; ZINC;

ARTICLE; BLOOD; CELL CULTURE; CHEMISTRY; COMPARATIVE STUDY; DRUG EFFECT; DRUG POTENTIATION; ESCHERICHIA COLI; GEL; GRAM NEGATIVE INFECTION; HUMAN; IMMUNOLOGY; MONONUCLEAR CELL; PHYSICAL CHEMISTRY; SECRETION;

ADJUVANTS, IMMUNOLOGIC; CATIONS, DIVALENT; CELLS, CULTURED; CHEMISTRY, PHYSICAL; DRUG SYNERGISM; ESCHERICHIA COLI; GELS; GRAM-NEGATIVE BACTERIAL INFECTIONS; HUMANS; INTERLEUKIN-1; LEUKOCYTES, MONONUCLEAR; LIPOPOLYSACCHARIDES; TETRADECANOYLPHORBOL ACETATE; TUMOR NECROSIS FACTOR-ALPHA; ZINC;

EID: 0030266626     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (38)

1. Bettger, W. J., and B. L. O'Dell. 1993. Physiological roles of zinc in the plasma membrane of mammalian cells. J. Nutr. Biochem. 4:194.
2. Cunningham-Rundles, S., R. S. Bockman, A. Lin, P. V. Giaidina, M. W. Hilgertner, D. Caldwell-Brown, and D. M. Carter. 1990. Physiological and pharmacological effects of zinc on immune response. Ann. NY Acad. Sci. 587:113.
3. Fraker, P. J., M. E. Gershwin, R. A. Good, and A. Prasad. 1986. Interrelationships between zinc and immune function. Fed. Proc. 45:1474.
4. Kruse-Jarres, J. D. 1989. The significance of zinc for humoral and cellular immunity. J. Trace Elem. Electrol. Health Dis. 3:1.
5. Keen, C. L., and M. E. Gershwin. 1990. Zinc deficiency and immune function. Annu. Rev. Nutr. 10:415.
6. Tanaka, Y., S. Shiozawa, I. Morimoto, and T. Fujita. 1990. Role of zinc in interleukin 2 (IL-2)-mediated T-cell activation. Scand. J. Immunol. 31:547.
7. Driessen, C., K. Hirv, L. Rink, and H. Kirchner. 1994. Induction of cytokines by zinc in human peripheral blood mononuclear cells and separated monocytes. Lymphokine Cytokine Res. 13:15.
8. Boukaiba, N., C. Flament, S. Archer, P. Chappuis, A. Piau, M. Fusselier, M. Dardenne, and D. Lemonnier. 1993. A physiological amount of zinc supplementation: effect on nutritional, lipid, and thymic status in an elderly population. Am. J. Clin. Nutr. 57:566.
9. Moraglio, D., D. Testa, and A. Arnell. 1993. Zinc status in intensely transfused patients. Vox Sang. 64:193.
10. Travaglini, P., P. Moriondo, E. Togni, P. Venegoni, D. Bochicchio, A. Conti, G. Ambroso, C. Ponticelli, E. Mocchegiani, N. Fabris, and G. Faglia. 1989. Effect of oral zinc administration on prolactin and thymulin circulating levels in patients with chronic renal failure. J. Clin. Endocrinol. Metab. 68:186.
11. Isa, L., A. Lucchini, S. Lodi, and M. Giachetti. 1992. Blood zinc status and zinc treatment in human immunodeficiency virus-infected patients. Int. J. Clin. Lab. Res. 22:45.
12. Duchateau, J., G. Delespesse, and P. Vereecke. 1981. Influence of oral zinc supplementation on the lymphocyte response to mitogens of normal subjects. Am. J. Clin. Nutr. 34:88.
13. Chow, A. W. 1980. Nosocomial infections. Infect. Dis. 20:262.
14. Young, L. S. 1981. Nosocomial infections in the immunocompromised adult. Am. J. Med. 70:394.
15. Bone, R. C. 1991. The pathogenesis of sepsis. Ann. Intern. Med. 115:457.
16. Lynn, W. A., and D. T. Golenbock. 1992. Lipopolysaccharide antagonists. Immunol. Today 13:271.
17. Heremans, H., R. Dijkmans, and H. Sobis. 1987. Regulation by interferons on the local inflammatory response to bacterial lipopolysaccharide. J. Immunol. 138: 4175.
18. Cavaillon, J. M. 1994. Cytokines and macrophages. Biomed. Pharmacother. 48: 445.
19. Seydel, U., H. Labschinski, M. Kastowsky, and K. Brandenburg. 1993. Phase behavior, supramolecular structure, and molecular conformation of lipopolysaccharide. Immunobiol. 187:191.
20. Seydel, U., and K. Brandenburg. 1992. Supramolecular structure of lipopolysaccharides and lipid A. In Bacterial Endotoxic Lipopolysaccharides, Vol. 1. CRC Press, Boca Raton, FL, p. 225.
21. Driessen, C., K. Hirv, H. Kirchner, and L. Rink. 1995. Zinc regulates cytokine induction by superantigens and lipopolysaccharide. Immunology 84:272.
22. Driessen, C., K. Hirv, H. Kirchner, and L. Rink. 1995. Divergent effects of zinc on different bacterial pathogenic agents. J. Infect. Dis. 171:486.
23. Hawkins, C. J. 1971. Absolute Configuration of Metal Complexes. Wiley Interscience, New York.
24. Lincoln, S. F. 1971. Solvent coordination numbers of metal ions in solution. Coord. Chem. Rev. 6:309.
25. Iann, K., and O. Westphal. 1965. Bacterial lipopolysaccharides. Extraction with phenol-water and further applications of the procedure. Methods Carbohydr. Chem. 5:83.
26. Galanos, C., O. Lüderitz, and O. Westphal. 1969. A new method for the extraction of R lipopolysaccharides. Eur. J. Biochem. 9:245.
27. Brandenburg, K., and U. Seydel. 1990. Investigations into the fluidity of lipopolysaccharide and free lipid A membrane systems by Fourier-transform infrared spectroscopy and differential scanning calorimetric. Eur. J. Biochem. 191:229.
28. Duckham, J. M., and H. A. Lee. 1976. The treatment of refractory anaemia of chronic renal failure with cobalt chloride. Q. J. Med. 45:277.
29. Gardner, F. H. 1953. Use of cobaltous chloride in anaemia associated with chronic renal disease. J. Lab. Clin. Med. 41:56.
30. Schroeder, H. A., J. J. Balassa, and J. H. Tipton. 1962. Abnormal trace metals in man: nickel. J. Chronic Dis. 15:51.
31. Sundermann, F. W., and J. F. Kincaid. 1954. Nickel poisoning. Studies on patients suffering from acute exposure of vapors of nickel compounds. JAMA 155: 889.
32. Wellinghausen, N., C. Driessen, and L. Rink. 1996. Stimulation of human peripheral blood mononuclear cells by zinc and related cations. Cytokine. In press.
33. Gearing, A. J. K., P. Beckett, M. Christodoulou, M. Churchill, J. M. Clements, M. Crimmin, A. H. Davidson, A. H. Drummond, W. A. Galloway, R. Gilbert, J. L. Gordon, T. M. Leber, M. Mangan, K. Miller, P. Nayee, K. Owen, S. Patel, W. Thomas, G. Wells, L. M. Wood, and K. Woolley. 1995. Matric metalloproteinases and processing of pro-TNF-alpha. J. Leukocyte Biol. 57:774.
34. Robachegallea, S., V. Morand, J. M. Bruneau, B. Schoot, E. Tagat, E. Realo, S. Chouaib, and S. Romanroman. 1995. In vitro processing of human tumor necrosis factor-alpha. J. Biol. Chem. 270:23688.
35. Wellinghausen, N., A. Fischer, H. Kirchner, and L. Rink. 1996. Interaction of zinc ions with human peripheral blood mononuclear cells. Cell. Immunol. In press.
36. Chandra, R. K. 1984. Excessive intake of zinc impairs immune responses. JAMA 252:1443.
37. Singh, A., B. L. Smoak, K. Y. Patterson, L. G. LeMay, C. Veillon, and P. A. Deuster. 1991. Biochemical indices of selected trace minerals in men: effect of stress. Am. J. Clin. Nutr. 53:126.
38. Kreger, B. E., D. E. Craven, and W. R. McCabe. 1980. Gram-negative bacteremia. IV. Re-evaluation of clinical features and treatment in 612 patients. Am. J. Med. 68:344.