메뉴 건너뛰기




Volumn 73, Issue 4, 1996, Pages 171-178

Age-related Reductions in Number and Size of Anterior Horn Cells at C6 Level of the Human Spinal Cord

Author keywords

Aging process; Anterior horn cells (AHCs); Human, morphometry; Spinal cord

Indexed keywords

ADULT; AGED; AGING; ARTICLE; CADAVER; CELL COUNT; CELL SIZE; CYTOLOGY; HUMAN; MALE; MIDDLE AGED; MOTONEURON; PHYSIOLOGY; SPINAL CORD; STATISTICAL MODEL;

EID: 0030266012     PISSN: 0030154X     EISSN: None     Source Type: Journal    
DOI: 10.2535/ofaj1936.73.4_171     Document Type: Article
Times cited : (52)

References (43)
  • 1
    • 0025330765 scopus 로고
    • Quantitative and qualitative morphological properties of the solcus motor nerve and the L5 ventral root in young and old rats
    • Ansved T and Larsson L. Quantitative and qualitative morphological properties of the solcus motor nerve and the L5 ventral root in young and old rats. J Neurol Sci 1990; 96:269-282.
    • (1990) J Neurol Sci , vol.96 , pp. 269-282
    • Ansved, T.1    Larsson, L.2
  • 2
    • 0013585582 scopus 로고
    • Changes, with age in the spinal cord
    • Bailey AA. Changes, with age in the spinal cord. Arch Neural Psychiat 1953; 70:299-309
    • (1953) Arch Neural Psychiat , vol.70 , pp. 299-309
    • Bailey, A.A.1
  • 3
    • 0018743122 scopus 로고
    • Morphology and physiology of skeletal muscle in aging rodents
    • Caccia MR, Harris JB and Johnson MA. Morphology and physiology of skeletal muscle in aging rodents. Muscle Nerve 1979; 2:202-212.
    • (1979) Muscle Nerve , vol.2 , pp. 202-212
    • Caccia, M.R.1    Harris, J.B.2    Johnson, M.A.3
  • 4
    • 0013586477 scopus 로고
    • The morbid changes in the cerebro-spinal nervous system of the aged insane
    • Campbell AW. The morbid changes in the cerebro-spinal nervous system of the aged insane. J Ment Sci 1894; 40:638-649.
    • (1894) J Ment Sci , vol.40 , pp. 638-649
    • Campbell, A.W.1
  • 6
    • 0010592777 scopus 로고
    • Spinal cord: Gross anatomy and internal structure
    • Carpenter, M.B. (ed): Williams & Wilkins. Baltimore, MD, 4th edn.
    • Carpenter MB Spinal cord: Gross anatomy and internal structure. In Carpenter, M.B. (ed): Core text of neuroanatomy. pp 57-82. Williams & Wilkins. Baltimore, MD, 4th edn., 1991.
    • (1991) Core Text of Neuroanatomy. , pp. 57-82
    • Carpenter, M.B.1
  • 7
    • 0002930404 scopus 로고
    • Neurology of old age
    • Critchley M. Neurology of old age. Lancet 1931; 1:1119-1127.
    • (1931) Lancet , vol.1 , pp. 1119-1127
    • Critchley, M.1
  • 8
    • 0042978625 scopus 로고
    • Incidence of mild degrees of atrophy in fasciculus gracilis
    • Duncan D Incidence of mild degrees of atrophy in fasciculus gracilis Arch Path 1938; 26:664-675.
    • (1938) Arch Path , vol.26 , pp. 664-675
    • Duncan, D.1
  • 9
    • 84907126125 scopus 로고
    • Discriminative staining methods for the nervous system: Luxol fast blue-periodic acid-Schiff-hematoxylin triple stain and subsidiary staining methods
    • Goto N. Discriminative staining methods for the nervous system: Luxol fast blue-periodic acid-Schiff-hematoxylin triple stain and subsidiary staining methods. Stain Technol 1987; 62:305-315.
    • (1987) Stain Technol , vol.62 , pp. 305-315
    • Goto, N.1
  • 10
    • 0041977074 scopus 로고
    • Gray and white matters of the spinal cord: Diagnostic criteria of the levels
    • Goto N. Gray and white matters of the spinal cord: Diagnostic criteria of the levels (in Japanese). Spine Spinal Cord 1988; 1:767-770.
    • (1988) Spine Spinal Cord , vol.1 , pp. 767-770
    • Goto, N.1
  • 11
    • 0023389190 scopus 로고
    • Changes by age group in the caudal level of termination of the spinal cord in Japanese adults
    • Hara K. Changes by age group in the caudal level of termination of the spinal cord in Japanese adults. Acta Anat Nippon 1987; 62:329-333.
    • (1987) Acta Anat Nippon , vol.62 , pp. 329-333
    • Hara, K.1
  • 12
    • 0023855520 scopus 로고
    • Medial gastrocnemius motor nucleus in the rat: Age-related changes in the number and size of motoneurons
    • Hashizume K, Kanda K and Burke RE. Medial gastrocnemius motor nucleus in the rat: Age-related changes in the number and size of motoneurons. J Comp Neurol 1988; 269:425-430.
    • (1988) J Comp Neurol , vol.269 , pp. 425-430
    • Hashizume, K.1    Kanda, K.2    Burke, R.E.3
  • 13
    • 0029061612 scopus 로고
    • Differential effects of aging on motoneurons and peripheral nerves innervating the hindlimb and forelimb muscles of rats
    • Hashizume K and Kanda K. Differential effects of aging on motoneurons and peripheral nerves innervating the hindlimb and forelimb muscles of rats. Neurosci Res 1995; 22:189-196.
    • (1995) Neurosci Res , vol.22 , pp. 189-196
    • Hashizume, K.1    Kanda, K.2
  • 14
    • 0015973973 scopus 로고
    • The numbers of limb motor neurones in the individual segments of the human lumbosacral spinal cord
    • Irving D, Rebeiz JJ and Tomlinson BE. The numbers of limb motor neurones in the individual segments of the human lumbosacral spinal cord. J Neurol Sci 1974; 21:203-212.
    • (1974) J Neurol Sci , vol.21 , pp. 203-212
    • Irving, D.1    Rebeiz, J.J.2    Tomlinson, B.E.3
  • 15
    • 0023521471 scopus 로고
    • Effects of ageing on the total number of muscle fibers and motoneurons of the tibialis anterior and soleus muscles in the rat
    • Ishihara A, Naitoh H and Katsuta S. Effects of ageing on the total number of muscle fibers and motoneurons of the tibialis anterior and soleus muscles in the rat. Brain Res 1987; 435:355-358.
    • (1987) Brain Res , vol.435 , pp. 355-358
    • Ishihara, A.1    Naitoh, H.2    Katsuta, S.3
  • 16
    • 0022368276 scopus 로고
    • Qualitative and quantitative morphology of human sural nerve at different ages
    • Jacobs JM and Love S. Qualitative and quantitative morphology of human sural nerve at different ages. Brain 1985; 108:897-924.
    • (1985) Brain , vol.108 , pp. 897-924
    • Jacobs, J.M.1    Love, S.2
  • 17
    • 0015005032 scopus 로고
    • Pathology of the spinal dorsal tract and dorsal roots of the aged
    • Kameyama M. Pathology of the spinal dorsal tract and dorsal roots of the aged (in Japanese). Shinkei Kenkyu no Shinpo 1971; 15:544-546.
    • (1971) Shinkei Kenkyu No Shinpo , vol.15 , pp. 544-546
    • Kameyama, M.1
  • 18
    • 0028148220 scopus 로고
    • Morphometry of the normal cadaveric cervical spinal cord
    • Kameyama T, Hashizume Y, Ando T and Takahashi A. Morphometry of the normal cadaveric cervical spinal cord. Spine 1994; 19:2077-2081.
    • (1994) Spine , vol.19 , pp. 2077-2081
    • Kameyama, T.1    Hashizume, Y.2    Ando, T.3    Takahashi, A.4
  • 19
    • 0017743936 scopus 로고
    • Counting of spinal neurons
    • Kanemitsu A Counting of spinal neurons (in Japanese). Shinkei Kenkyu no Shinpo 1977; 21:496-504.
    • (1977) Shinkei Kenkyu No Shinpo , vol.21 , pp. 496-504
    • Kanemitsu, A.1
  • 20
    • 0017666018 scopus 로고
    • Lumbar motoneurons of man: I Number and diameter histogram of alpha and gamma axons of ventral root
    • Kawamura Y. Okazaki H, O'Brien PC and Dyck PJ. Lumbar motoneurons of man: I) Number and diameter histogram of alpha and gamma axons of ventral root. J Neuropathol Exp Neurol 1977; 36:853-860.
    • (1977) J Neuropathol Exp Neurol , vol.36 , pp. 853-860
    • Kawamura, Y.1    Okazaki, H.2    O'Brien, P.C.3    Dyck, P.J.4
  • 21
    • 0017703644 scopus 로고
    • Lumbar motoneurons of man II: The number and diameter distribution of large- And intermediate-diameter cytons in "motoneuron columns" of spinal cord of man
    • Kawamura Y, Okazaki H, O'Brien PC and Dyck PJ. Lumbar motoneurons of man II: The number and diameter distribution of large- and intermediate-diameter cytons in "motoneuron columns" of spinal cord of man. J Neuropathol Exp Neurol 1977; 36:861-870.
    • (1977) J Neuropathol Exp Neurol , vol.36 , pp. 861-870
    • Kawamura, Y.1    Okazaki, H.2    O'Brien, P.C.3    Dyck, P.J.4
  • 22
    • 0041339570 scopus 로고
    • The architecture change of the human anterior tibial muscle fibers with aging process
    • Kimura T, Yanagisawa K, Goto N and Inokuchi S. The architecture change of the human anterior tibial muscle fibers with aging process (in Japanese). Acta Anat Nippon 1995; 70(Suppl):S216.
    • (1995) Acta Anat Nippon , vol.70 , Issue.SUPPL.
    • Kimura, T.1    Yanagisawa, K.2    Goto, N.3    Inokuchi, S.4
  • 23
    • 0018113372 scopus 로고
    • Morphological and functional characteristics of the ageing skeletal muscle in man. A cross-sectional study
    • Larsson L. Morphological and functional characteristics of the ageing skeletal muscle in man. A cross-sectional study. Acta Physiol Scand 1978; 457(Suppl):1-36.
    • (1978) Acta Physiol Scand , vol.457 , Issue.SUPPL. , pp. 1-36
    • Larsson, L.1
  • 24
    • 0023129278 scopus 로고
    • Age-related reduction in 8th cervical ventral nerve root myelinated fiber diameters and numbers in man
    • Mittal KR and Logmani FH. Age-related reduction in 8th cervical ventral nerve root myelinated fiber diameters and numbers in man. J Gerontol 1987; 42:8-10.
    • (1987) J Gerontol , vol.42 , pp. 8-10
    • Mittal, K.R.1    Logmani, F.H.2
  • 26
    • 0024990420 scopus 로고
    • Motor neuron disease: Quantitative morphological and microdensitophotometric studies of neurons of anterior horn and ventral root of cervical spinal cord with special reference to the pathogenesis
    • Murakami T. Motor neuron disease: quantitative morphological and microdensitophotometric studies of neurons of anterior horn and ventral root of cervical spinal cord with special reference to the pathogenesis. J Neurol Sci 1990; 99:101-115.
    • (1990) J Neurol Sci , vol.99 , pp. 101-115
    • Murakami, T.1
  • 27
    • 84958691189 scopus 로고
    • Age changes in the maximum conduction velocity of motor fibers of human ulnar nerves
    • Norris A, Shock NW and Wagman IH. Age changes in the maximum conduction velocity of motor fibers of human ulnar nerves. J Appl Physiol 1953; 5:589-593.
    • (1953) J Appl Physiol , vol.5 , pp. 589-593
    • Norris, A.1    Shock, N.W.2    Wagman, I.H.3
  • 29
    • 0025864703 scopus 로고
    • Morphometric study of cervical anterior horn cells and pyramidal tracts in medulla oblongata and the spinal cord in patients with cerebrovascular diseases
    • Qiu Y, Wada Y, Otomo E and Tsukagoshi H. Morphometric study of cervical anterior horn cells and pyramidal tracts in medulla oblongata and the spinal cord in patients with cerebrovascular diseases. J Neurol Sci 1991; 102:137-143.
    • (1991) J Neurol Sci , vol.102 , pp. 137-143
    • Qiu, Y.1    Wada, Y.2    Otomo, E.3    Tsukagoshi, H.4
  • 30
    • 76949120541 scopus 로고
    • The cytoarchitectonic organization of the spinal cord in the cat
    • Rexed B. The cytoarchitectonic organization of the spinal cord in the cat. J Comp Neurol 1952; 96:415-495.
    • (1952) J Comp Neurol , vol.96 , pp. 415-495
    • Rexed, B.1
  • 31
    • 0016260534 scopus 로고
    • Age differences in the morphology of posterior tibial nerves of mice
    • Samorajski T. Age differences in the morphology of posterior tibial nerves of mice. J Comp Neurol 1974; 157:439-445.
    • (1974) J Comp Neurol , vol.157 , pp. 439-445
    • Samorajski, T.1
  • 33
    • 0029142639 scopus 로고
    • Synaptic loss in the proximal axon of anterior horn neurons in motor neuron disease
    • Sasaki S and Iwata M. Synaptic loss in the proximal axon of anterior horn neurons in motor neuron disease. Acta Neuropathol 1995; 90:170-175.
    • (1995) Acta Neuropathol , vol.90 , pp. 170-175
    • Sasaki, S.1    Iwata, M.2
  • 34
    • 0000584415 scopus 로고
    • The aging human peripheral nervous system
    • Katzman, R. and Terry, R.D. (Eds): F.A. Davis, Philadelphia
    • Schaumburg HH, Spencer PS and Ochoa J. The aging human peripheral nervous system. In Katzman, R. and Terry, R.D. (Eds): The Neurology of Aging, pp 111-122, F.A. Davis, Philadelphia, 1983.
    • (1983) The Neurology of Aging , pp. 111-122
    • Schaumburg, H.H.1    Spencer, P.S.2    Ochoa, J.3
  • 35
    • 0042341388 scopus 로고
    • Preliminary computations of the number of motoneurons in the human spinal cord
    • Sirken CR and Kuhlenbeck H. Preliminary computations of the number of motoneurons in the human spinal cord. Anat Rec 1966; 154:489.
    • (1966) Anat Rec , vol.154 , pp. 489
    • Sirken, C.R.1    Kuhlenbeck, H.2
  • 36
    • 0027228525 scopus 로고
    • A quantitative pathological investigation of the cervical cord, roots and ganglia after long-term amputation of the unilateral upper arm
    • Suzuki H, Oyanagi K, Takahashi H, Kono M, Yokoyama M and Ikuta F. A quantitative pathological investigation of the cervical cord, roots and ganglia after long-term amputation of the unilateral upper arm. Acta Neuropathol 1993; 85:666-673.
    • (1993) Acta Neuropathol , vol.85 , pp. 666-673
    • Suzuki, H.1    Oyanagi, K.2    Takahashi, H.3    Kono, M.4    Yokoyama, M.5    Ikuta, F.6
  • 37
    • 0022978658 scopus 로고
    • Focal loss of anterior horn cells in the cervical cord in motor neuron disease
    • Swash M, Leader M, Brown A and Swettenham KW. Focal loss of anterior horn cells in the cervical cord in motor neuron disease. Brain 1986; 109:939-952.
    • (1986) Brain , vol.109 , pp. 939-952
    • Swash, M.1    Leader, M.2    Brown, A.3    Swettenham, K.W.4
  • 38
    • 0017653297 scopus 로고
    • Quantitative changes with age in normal sural nerves
    • Tohgi H, Tsukagoshi H and Toyokura Y. Quantitative changes with age in normal sural nerves. Acta Neuropath (Bert) 1977; 38:213-220.
    • (1977) Acta Neuropath (Bert) , vol.38 , pp. 213-220
    • Tohgi, H.1    Tsukagoshi, H.2    Toyokura, Y.3
  • 39
    • 0017698204 scopus 로고
    • The numbers of limb motor neurons in the human lumbosacral cord throughout life
    • Tomlinson BE and Irving D. The numbers of limb motor neurons in the human lumbosacral cord throughout life. J Neurol Sci 1977; 34:213-219.
    • (1977) J Neurol Sci , vol.34 , pp. 213-219
    • Tomlinson, B.E.1    Irving, D.2
  • 40
    • 0018341399 scopus 로고
    • Morphometric quantification of the cervical limb motor cells in controls and in amyotrophic lateral sclerosis
    • Tsukagoshi H, Yanagisawa N, Oguchi K, Nagashima K and Murakami T. Morphometric quantification of the cervical limb motor cells in controls and in amyotrophic lateral sclerosis. J Neurol Sci 1979; 41:287-297.
    • (1979) J Neurol Sci , vol.41 , pp. 287-297
    • Tsukagoshi, H.1    Yanagisawa, N.2    Oguchi, K.3    Nagashima, K.4    Murakami, T.5
  • 41
    • 0001247970 scopus 로고
    • A study of the loss of nerve cells in the central nervous system in relation to age
    • Wright EA and Spink JM. A study of the loss of nerve cells in the central nervous system in relation to age. Gerontologia (Basel) 1959; 3:277-287.
    • (1959) Gerontologia (Basel) , vol.3 , pp. 277-287
    • Wright, E.A.1    Spink, J.M.2
  • 42
    • 0029433968 scopus 로고
    • Morphometric analyses and aging process of nerve fibers in the human spinal posterior funiculus
    • Zhang C, Goto N and Zhou M. Morphometric analyses and aging process of nerve fibers in the human spinal posterior funiculus. Okajimas Folia Anat Jpn 1995; 72:259-264.
    • (1995) Okajimas Folia Anat Jpn , vol.72 , pp. 259-264
    • Zhang, C.1    Goto, N.2    Zhou, M.3
  • 43
    • 0347266146 scopus 로고    scopus 로고
    • Morphometric analysis of age-related changes in the human cervical spinal cord
    • in press
    • Zhang C, Zhou M, Shiraishi N and Goto N. Morphometric analysis of age-related changes in the human cervical spinal cord. Showa Univ J Med Sci 1996; 8: (in press).
    • (1996) Showa Univ J Med Sci , vol.8
    • Zhang, C.1    Zhou, M.2    Shiraishi, N.3    Goto, N.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.