High spatial resolution MRI and proton MRS of human frontal cortex

NMR in Biomedicine

Volumn 9, Issue 7, 1996, Pages 297-304

  López Villegas, Dolores ^a,b   Kimura, Hirohiko ^a   Tunlayadechanont, Supoch ^a   Lenkinski, Robert E ^a  

^a HOSPITAL OF THE UNIVERSITY OF PENNSYLVANIA   (United States)

^b HOSPITAL DE LA SANTA CREU I SANT PAU   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

ASPARTIC ACID; CHOLINE; CREATINE; CREATINE PHOSPHATE; DRUG DERIVATIVE; N ACETYLASPARTIC ACID; N-ACETYLASPARTATE; PROTON;

ADULT; ARTICLE; BRAIN LEVEL; FRONTAL LOBE; HISTOLOGY; HUMAN; INSTRUMENTATION; METHODOLOGY; NUCLEAR MAGNETIC RESONANCE IMAGING; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; REFERENCE VALUE;

ADULT; ASPARTIC ACID; BRAIN CHEMISTRY; CHOLINE; CREATINE; FRONTAL LOBE; HUMANS; MAGNETIC RESONANCE IMAGING; MAGNETIC RESONANCE SPECTROSCOPY; PHOSPHOCREATINE; PROTONS; REFERENCE VALUES;

ILEX COOKII;

EID: 0030265350     PISSN: 09523480     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1099-1492(199610)9:7<297::AID-NBM433>3.0.CO;2-4     Document Type: Article

References (29)

1. Nadler, J. V. and Cooper, J. R. N-acetyl-L-apartic acid content of human neural tumors and bovine peripheral nervous tissues, J. Neurochem. 19, 313-319 (1972).
2. Birken, D. L. and Oldendorf, W. H. N-acetyl-L-aspartic acid: a literature review of a compound prominent in 1H-NMR spectroscopic studies of brain. Neurosci. Biobehav. Rev. 13, 23-31 (1989).
3. van der Knaap, M. S., van der Grond, J., Luvten, P. R., den Hollander, J. A., Nauta, J. J. P. and Valk, J. 1H and 31P magnetic resonance spectroscopy of the brain in degenerative cerebral disorders. Ann. Neurol. 31, 202-211 (1992).
4. Miller, B. L., Moats, R. A., Shonk, T., Ernst, T., Woolley, S. and Ross, B. D. Alzheimer disease: depiction of increased cerebral myo-inositol with proton MR spectroscopy. Radiology 187, 433-437 (1993).
5. Meyerhoff, D. J., Mackay, S., Constants, J. M., Norman, D., Van Dyke, C., Fein, G. and Weiner, M. W. Axonal injury and membrane alterations in Alzheimer's disease suggested by in vivo proton magnetic resonance spectroscopic imaging. Ann. Neurol. 36, 40-47 (1994).
6. Shiino, A., Matsuda, M., Morikawa, S., Inubushi, T., Akiguchi, I. and Handa, J. Proton magnetic resonance spectroscopy with dementia. Surg. Neurol. 39, 143-147 (1993).
7. Jenkins, B. G., Koroshetz, W. J., Flint Beal, M. and Rosen, B. R. Evidence for impairment of energy metabolism in vivo in Huntington's disease using localized 1H NMR spectroscopy. Neurology 43, 2689-2695 (1993).
8. Weis, S., Haug, H., Holoubek, B. and Örün, H. The cerebral dominances: quantitative morphology of the human cerebral cortex. J. Neurosci. 47, 165-168 (1989).
9. Kreis, R., Ernst, T. and Ross, B. D. Absolute quantification of water and metabolites in the human brain. II. Metabolite concentrations. J. Magn. Reson. B 102, 9-19 (1993).
10. Petroff, O. A. C., Spencer, D. D., Alger, J. R. and Pritchard, J. W. High-field proton magnetic resonance spectroscopy of human cerebrum obtained during surgery for epilepsy. Neurology 39, 1197-1202 (1989).
11. Vigneron, D. B., Wald, L. U, Day, M., Moyher, S. E., Norman, D., Dillon, W. and Nelson, S. J. Detection of metabolic heterogeneity in human brain tumors by 3-dimensional high spatial resolution (0.2-0.4 cc) 1H MR spectroscopic imaging. Proceedings, SMRM, 13th Annual Meeting, San Francisco, p. 1170 (1994).
12. Hetherington, H. P., Mason, G. F., Pan, J. W., Ponder, S. L., Vaughan, J. T., Twieg, D. B. and Pohost, G. M. Evaluation of cerebral gray and white matter metabolite differences by spectroscopic imaging at 4.1 T. Magn. Reson. Med. 32, 565-571 (1994).
13. Kreis, R. and Ross, B. D. Cerebral metabolic disturbances in patients with subacute and chronic diabetes mellitus: detection with proton MR spectroscopy. Radiology 184, 123-130 (1992).
14. Webb, P. G., Sailasuta, N., Kohler, S. J., Raidy, T., Moats, R. A. and Hurd, R. E. Automated single-voxel proton MRS: technical development and multisite verification. Magn. Reson. Med. 31, 365-373 (1994).
15. Nicoli, F., Vion-Dury, J., Maloteaux, J. M., Delwaide, C., Confort-Gouny, S., Sciaky, M. and Cozzone, P. J. CSF and serum metabolic profile of patients with Huntington's chorea: a study by high-resolution proton NMR spectroscopy and HPLC. Neurosci. Lett. 154, 47-51 (1993).
16. Petroff, O. A. C., Yu, R. K. and Ogino, T. High-resolution proton magnetic resonance analysis of human cerebrospinal fluid. J. Neurochem. 47, 1270-1276 (1986).
17. Bell, J. D., Brown, J. C. C., Sadler, P. J., Macleod, A. F., Sonksen, P. H., Hughes, R. D. and Williams, R. Highresolution proton nuclear magnetic resonance studies of human cerebrospinal fluid. Clin. Sci. 72, 563-570 (1987).
18. Lewis, L. D., Ljunggren, B., Ratcheson, R. A. and Siesjo, B. K. Cerebral energy state in insulin-induced hypoglycemia, related to blood glucose and EEG. J. Neurochem. 23, 673-679 (1974).
19. Narayana, P. A., Fotedar, L. K., Jackson, E. F., Bohan, T. P., Butler, I. J. and Wolinsky, J. S. Regional in vivo proton magnetic resonance spectroscopy of brain. J. Magn. Reson. 83, 44-52 (1989).
20. Petroff, O. A. C., Ogino, T. and Alger, J. R. High-resolution proton magnetic resonance spectroscopy of brain: regional metabolite levels and postmortem changes. J. Neurochem. 51, 163-171 (1988).
21. Barker, P. B., Lee, R. R. and McArthur, J. C. AIDS dementia complex: evaluation with proton MR spectroscopic imaging. Radiology 195, 58-64 (1995).
22. Michaelis T., Merboldt, K.-D., Bruhn, H., Hänicke, W. and Frahm, J. Absolute concentrations of metabolites in the adult human brain in vivo: quantification of localized proton MR spectra. Radiology 187, 219-227 (1993).
23. Tallan, H. H. Studies on the distribution of N-acetyl-L-aspartic acid in brain. J. Biol. Chem. 224, 41-45 (1957).
24. Miyake, M., Kakimoto, Y. and Sorimachi, M. A gas Chromatographic method for the determination of N-acetyl-L-aspartic acid, N-acetyl-α-aspartylglutamic acid and β-citryl-L-glutamic acid and their distributions in the brain and other organs of various species of animals. J. Neurochem. 36, 804-810 (1981).
25. Hanstock, C. C., Rothman, D. L., Prichard, J. W., Jue, T. and Shulman, R. G. Spatially localized 1H NMR spectra of metabolites in the human brain. Proc. Natl Acad. Sci. USA 85, 1821-1825 (1988).
26. Frahm, J., Bruhn, H., Gyncell, M. L., Merboldt, K. D., Hanicke, W. and Sauter, R. Localized proton NMR spectroscopy in different regions of the human brain in vivo. Relaxation times and concentrations of cerebral metabolites. Magn. Reson. Med. 11, 47-63 (1989).
27. Tedeschi, G., Righini, A., Bizzi, A., Barnett, A. S. and Alger, J. R. Cerebral white matter in the centrum semiovale exhibits a larger W-acetyl signal than does gray matter in long echo time. 1H-magnetic resonance spectroscopic imaging. Magn. Reson. Med. 33, 127-133 (1995).
28. Goldstein, F. B. Amidohydrolases of brain: enzymatic hydrolysis of N-acetyl-L-aspartate and other N-acetyl-L-amino acids. J. Neurochem. 26, 45-49 (1976).
29. d'Adamo, A. F., Smith, J. C. and Woiler, C. The occurrence of N-acetylaspartate amidohydrolase (aminoacylase II) in the developing rat. J. Neurochem. 20, 1275-1278 (1973).