Heparin-induced thrombocytopenia: What the serologists have taught us

Journal of Laboratory and Clinical Medicine

Volumn 128, Issue 4, 1996, Pages 346-348

  Kelton, J G ^a   Warkentin, T E ^a  

^a MCMASTER UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0030257392     PISSN: 00222143     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0022-2143(96)80003-5     Document Type: Editorial

References (20)

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12. Amiral J Bridey F Dreyfus M Platelet factor 4 complexed to heparin is the target for antibodies generated in heparin-induced thrombocytopenia Thromb Haemost 68 1992 95 96
13. Visentin GP Ford SE Scott JP Aster RH Antibodies from patients with heparin-induced thrombocytopenia/thrombosis are specific for platelet factor 4 complexed with heparin or bound to endothelial cells J Clin Invest 93 1994 81 88
14. Greinacher A Pötzsch B Amiral J Dummel V Eichner A Mueller-Eckhardt C Heparin-associated thrombocytopenia: isolation of the antibody and characterization of a multimolecular PF4-heparin complex as the major antigen Thromb Haemost 71 1994 247 251
15. Kelton JG Smith JW Warkentin TE Hayward CPM Denomme GA Horsewood P Immunoglobulin G from patients with heparin-induced thrombocytopenia binds to a complex of heparin and platelet factor 4 Blood 83 1994 3232 3239
16. Kelton JG Sheridan D Santos A Heparin-induced thrombocytopenia: laboratory studies Blood 72 1988 925 930
17. Visentin GP Malik M Cyganiak KA Aster RH Patients treated with unfractionated heparin during open heart surgery are at high risk to form antibodies reactive with heparin:platelet factor 4 complexes J Lab Clin Med 128 1996 376 383
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