A computational study on the relative reactivity of reductively activated 1,4-benzoquinone and its isoelectronic analogs

Journal of Computer-Aided Molecular Design

Volumn 10, Issue 5, 1996, Pages 441-460

  Mariam, Yitbarek H ^a  

^a CLARK ATLANTA UNIVERSITY   (United States)

Author keywords

5 iminodaunomycin; Anthracyclines; Oxidizability; P benzoquinone; P benzoquinone imine; Redox capacity; Redox cycling; Reducibility; Relative reactivity

Indexed keywords

ACTIVATION ANALYSIS; CALCULATIONS; CHEMICAL ACTIVATION; ELECTRONS; ENTHALPY; FORECASTING; IONIZATION POTENTIAL;

5-IMINODAUNOMYCIN; ANTHRACYCLINES; OXIDIZABILITY; P-BENZOQUINONE; P-BENZOQUINONE IMINE; REDOX CAPACITY; REDOX CYCLING; REDUCIBILITY; RELATIVE REACTIVITIES;

ELECTRON AFFINITY;

1,4 BENZOQUINONEIMINE; 1,4-BENZOQUINONEIMINE; ANTINEOPLASTIC ANTIBIOTIC; BENZOQUINONE; BENZOQUINONE DERIVATIVE; IMINE; REACTIVE OXYGEN METABOLITE;

ARTICLE; BINDING SITE; CHEMICAL STRUCTURE; CHEMISTRY; COMPARATIVE STUDY; COMPUTER AIDED DESIGN; DRUG DESIGN; ELECTROCHEMISTRY; OXIDATION REDUCTION REACTION; THERMODYNAMICS;

ANTIBIOTICS, ANTINEOPLASTIC; BENZOQUINONES; BINDING SITES; COMPUTER-AIDED DESIGN; DRUG DESIGN; ELECTROCHEMISTRY; IMINES; MODELS, MOLECULAR; OXIDATION-REDUCTION; REACTIVE OXYGEN SPECIES; THERMODYNAMICS;

EID: 0030256644     PISSN: 0920654X     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF00124475     Document Type: Article

References (1)

1. Lace, J.K. and Curran, C.F., In Baskin, S.I. (Ed.) Principles of Cardiac Toxicology, CRC Press, Boca Raton, FL, U.S.A., 1991, and references cited therein.