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The major locus for multifactorial nonsyndromic cleft lip maps to mouse Chromosome 11
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Genetic analysis of the construction of the AEJ.A congenic strain indicates that nonsyndromic CL(P) in the mouse is caused by two loci with epistatic interaction
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The alymphoplasia (aly) mutation co-segregates with the intercellular adhesion molecule-2 (Icam-2) on mouse chromosome 11
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Mouse Chromosome 11
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Further evidence of a relationship between the retinoic acid receptor locus and nonsyndromic cleft lip with or without cleft palate (CL ± P)
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Shaw, D., Ray, A., Marazita, M., Field, L. (1993). Further evidence of a relationship between the retinoic acid receptor locus and nonsyndromic cleft lip with or without cleft palate (CL ± P). Am. J. Hum. Genet. 53, 1156-1157.
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