Identification of peptide sequences that bind the Thomsen-Friedenreich cancer-associated glycoantigen from bacteriophage peptide display libraries

Molecular Diversity

Volumn 2, Issue 1-2, 1996, Pages 13-18

  Peletskaya, Elena N ^a   Glinsky, Gennadi ^b   Deutscher, Susan L ^a   Quinn, Thomas P ^a  

^a University of Missouri   (United States)

^b Cancer Research Center   (United States)

Author keywords

Bacteriophage display; Cancer associated glycoantigen; Peptide carbohydrate interactions; Random peptide libraries; Thomsen Friedenreich antigen

Indexed keywords

FLUORESCENT DYE; PEPTIDE; PEPTIDE LIBRARY; TN ANTIGEN; TUMOR ANTIGEN;

AMINO ACID SEQUENCE; ANIMAL; ARTICLE; CARCINOMA; CELL CULTURE; COLON TUMOR; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; INOVIRIDAE; ISOLATION AND PURIFICATION; MELANOMA; METABOLISM; MOLECULAR GENETICS; MOUSE;

AMINO ACID SEQUENCE; ANIMALS; ANTIGENS, TUMOR-ASSOCIATED, CARBOHYDRATE; CARCINOMA; COLONIC NEOPLASMS; ENZYME-LINKED IMMUNOSORBENT ASSAY; FLUORESCENT DYES; HUMANS; INOVIRIDAE; MELANOMA; MICE; MOLECULAR SEQUENCE DATA; PEPTIDE LIBRARY; PEPTIDES; TUMOR CELLS, CULTURED;

EID: 0030252924     PISSN: 13811991     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF01718695     Document Type: Article

References (12)

1. Hakomori, S., Possible functions of tumor-associated carbohydrate antigens, Curr. Opin. Immunol., 3 (1991) 646-653.
2. Springer, G.F., T and Tn: General carcinoma autoantigens, Science, 224 (1984) 1198-1206.
3. Hakomori, S., Aberrant glycosylation in tumors and tumor-associated carbohydrate antigens, Adv. Cancer Res., 52 (1989) 257-331.
4. Springer, G.F. and Desai, P.R., Extent of desialation of blood group MM, NN, and MN antigens for reactivity with human anti-T-antibody and Arachis hypogaea lectin, J. Biol. Chem., 257 (1982) 2744-2746.
5. Springer, G.F., Cheingsong-Popov, R., Schirrmacher, V., Desai, P.R. and Tegtmeyer, H., Proposed molecular basis of murine tumor cell-hepatocyte interaction, J. Biol. Chem., 258 (1983) 5702-5706.
6. Glinsky, G., Cell adhesion and metastasis: Is the site specificity of cancer metastasis determined by leukocyte-endothelial cell recognition and adhesion?, Crit. Rev. Oncol. Hematol., 14 (1993) 229-278.
7. Parmley, S.F. and Smith, G.P., Antibody-selectable filamentous fd phage vectors: Affinity purification of target genes, Gene, 73 (1988) 305-318.
8. Smith, G.P. and Scott, J.K., Libraries of proteins and peptides displayed on filamentous phage. Methods Enzymol., 217 (1993) 228-257.
9. Lotan, R., Skutelsky, E., Danon, D. and Sharon, N., The purification, composition, and specificity of the anti-T-lectin from peanut (Arachis hypogaea), J. Biol. Chem., 250 (1975) 8518-8523.
10. Haas, S.J. and Smith, G.P., Rapid screening of viral DNA from filamentous bacteriophage, Biotechniques, 15 (1993) 422-424.
11. Rutenber, E. and Robertus, J.D., Structure of ricin B-chain at 2.5 Å resolution, Proteins, 10 (1991) 260-269.
12. Springer, T. and Lasky, L., Sticky sugars for selectins, Nature, 349 (1991) 196-197.