The prolactin inhibition of follicle-stimulating hormone-induced aromatase activity in cultured rat granulosa cells is in part tyrosine kinase and protein kinase-C dependent

Molecular Human Reproduction

Volumn 2, Issue 10, 1996, Pages 725-731

  Villanueva, Luis Alberto ^a   Méndez, Isabel ^a   Ampuero, Sandra ^b   Larrea, Fernando ^a  

^a INSTITUTO NACIONAL DE CIENCIAS MÉDICAS Y NUTRICIÓN SALVADOR ZUBIRÁN   (Mexico)

^b PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE   (Chile)

Author keywords

Ovary; Prolactin; Protein kinases; Steroidogenesis

Indexed keywords

8 BROMO CYCLIC AMP; AROMATASE; CYCLIC AMP; ENZYME INHIBITOR; ESTRADIOL; FOLLITROPIN; GENISTEIN; ISOFLAVONE DERIVATIVE; PROLACTIN; PROTEIN KINASE C; PROTEIN TYROSINE KINASE; STAUROSPORINE;

ANIMAL; ARTICLE; BIOSYNTHESIS; CELL CULTURE; CHEMISTRY; CULTURE MEDIUM; DRUG ANTAGONISM; DRUG EFFECT; ENZYME INDUCTION; ENZYMOLOGY; FEMALE; GENETICS; GRANULOSA CELL; PHOSPHORYLATION; PHYSIOLOGY; PROTEIN PROCESSING; RAT; WISTAR RAT;

8-BROMO CYCLIC ADENOSINE MONOPHOSPHATE; ANIMALS; AROMATASE; CELLS, CULTURED; CULTURE MEDIA, CONDITIONED; CYCLIC AMP; ENZYME INDUCTION; ENZYME INHIBITORS; ESTRADIOL; FEMALE; FOLLICLE STIMULATING HORMONE; GENISTEIN; GRANULOSA CELLS; ISOFLAVONES; PHOSPHORYLATION; PROLACTIN; PROTEIN KINASE C; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN-TYROSINE KINASES; RATS; RATS, WISTAR; STAUROSPORINE;

EID: 0030252720     PISSN: 13609947     EISSN: None     Source Type: Journal    
DOI: 10.1093/molehr/2.10.725     Document Type: Article

References (42)

1. Banerjee, R. and Vonderhaar, B.K. (1992) Prolactin-induced protein kinase C activity in a mouse mammary cell line. Mol. Cell. Endocrinol., 90, 61-67.
2. Barkey, R.J., Weiss-Messer, E., Mandel, S. et al. (1987) Prolactin and antiprolactin receptor antibody inhibit steroidogenesis by purified rat Leydig cells in culture. Mol. Cell. Endocrinol., 52, 71-80.
3. Buckley, A.R., Crowe, P.D. and Russell, D.H. (1988) Rapid activation of protein kinase C in isolated rat liver nuclei by prolactin, a known hepatic mitogen. Proc. Natl. Acad. Sci. USA, 85, 8649-8653.
4. Buckley, A.R., Buckley, D.J., Gout, P.W. et al. (1993) Inhibition by genistein of prolactin-induced Nb2 lymphoma cell mitogenesis. Mol. Cell. Endocrinol., 98, 17-25.
5. Demura, R., Ono, M., Demura, H. et al. (1982) Prolactin directly inhibits basal as well as gonadotropin-stimulated secretion of progesterone and 17β-estradiol in the human ovary. J. Clin. Endocrinol. Metab., 54, 1246-1250.
6. DeVito, W.J., Stone, S. and Avakian, C. (1991) Prolactin stimulation of protein kinase C activity in the rat hypothalamus. Biochem. Biophys. Res. Commun., 176, 660-667.
7. Dorrington, J.H. and Gore-Langton, R.E. (1981) Prolactin inhibits oestrogen synthesis in the ovary. Nature, 290, 600-602.
8. Dorrington, J.H. and Gore-Langton, R.E. (1982) Antigonadal action of prolactin: further studies on the mechanism of inhibition of follicle-stimulating hormone-induced aromatase activity in rat granulosa cells in culture. Endocrinology, 110, 1701-1707.
9. Elberg, G., Kelly, P.A., Djiane, J. et al. (1990) Mitogenic and binding properties of monoclonal antibodies to the prolactin receptor in Nb2 rat lymphoma cells. Selective enhancement by anti-mouse IgG. J. Biol. Chem., 265, 14770-14776.
10. Flores, J.A., Garmey, J.C., Nestler, J.E. and Veldhuis, J.D. (1993) Sites of inhibition of steroidogenesis by activation of protein Kinase-C in Swine ovarian (granulosa) cells. Endocrinology, 132, 1983-1990.
11. Fortune, J.E. and Vincent, S.E. (1986) Prolactin modulates steroidogenesis by rat granulosa cells: I. Effects on progesterone. Biol. Reprod., 35, 84-91.
12. Fortune, J.E. Wissler, R.N. and Vincent, S.E. (1986) Prolactin modulates steroidogenesis by rat granulosa cells: II. Effects on estradiol. Biol. Reprod., 35, 92-99.
13. Gouilleux, F., Wakao H., Mundt, M. and Groner, B. (1994) Prolactin induces phosphorylation of Tyr694 of Stat5 (MGF), a prerequisite for DNA binding and induction of transcription. EMBO J., 13, 4361-4369.
14. He, H., Herington, A.C. and Roupas, P. (1995) Effect of protein kinase C modulation on gonadotrophin-induced granulosa cell steroidogenesis. Reprod. Fertil. Dev., 7, 83-95.
15. Hidaka, H. and Kobayashi, R. (1992) Pharmacology of protein kinase inhibitors. Ann. Rev. Pharmacol. Toxicol., 32, 377-397.
16. Jia, X.-C. and Hsueh, J.W. (1986) Granulosa cell aromatase bioassay for follicle-stimulating hormone: validation and application of the method. Endocrinology, 119, 1570-1577.
17. Knecht, M., Katz, M.S. and Catt, K.J. (1981) Gonadotropin-releasing hormone inhibits cyclic nucleotide accumulation in cultured granulosa cells. J. Biol. Chem., 256, 34-36.
18. Krasnow, J.S., Hickey, G.J. and Richards, J.S. (1990) Regulation of aromatase mRNA and estradiol biosynthesis in rat ovarian granulosa and luteal cells by prolactin. Mol. Endocrinol., 4, 13-22.
19. Lambert, A., Talbot, J.A., Mitchell, R. and Robertson, W.R. (1991) Inhibition of protein kinase C by staurosporine increases estrogen secretion by rat Sertoli cells. Acta Endocrinol., 125, 286-296.
20. Larrea, F., Escorza, A. and Oliart, R. (1991) Prolactin isohormones and fertility. In Negro-Vilar, A. and Pérez-Palacios, G. (eds), Reproduction, Growth and Development. Vol. 7. Serono Symposia Publications, Raven Press, New York, p. 427.
21. Larrea, F., Sandoval, J.L., Saunas, E. et al. (1995) Evidence for an altered luteinizing hormone sensitivity to naloxone in pathological hyperprolactinaemia. Clin. Endocrinol., 43, 591-600.
22. Lebrun, J.-J., Ali, S., Sofer, L. et al. (1993) Prolactin induced proliferation of Nb2 cells involves tyrosine phosphorylation of the prolactin receptor and its associated tyrosine kinase JAK2. J. Biol. Chem., 269, 14021-14026.
23. Lebrun, J.-J., Ali, S., Goffin, Y. et al. (1995) A single phosphotyrosine residue of the prolactin receptor is responsible for activation of gene transcription. Proc. Natl. Acad. Sci. USA, 92, 4031-4035.
24. Levitzki, A. and Grazit, A. (1995) Tyrosine kinase inhibition: an application to drug development. Science, 267, 1782-1788.
25. Matsuzaki, Y., Azuma, K., Irahara, M. et al. (1994) Mechanism of anovulation in hyperprolactinemic amenorrhea determined by pulsatile gonadotropin-releasing hormone injection combined with human chorionic gonadotropin. Fertil. Steril., 67, 1143-1149.
26. McNatty, K.P., Sawers, R.S. and McNeilly, A.S. (1974) A possible role for prolactin in control of steroid secretion by the human Graafian follicle. Nature, 250, 653-655.
27. Nagano, M. and Kelly, P.A. (1994) Tissue distribution and regulation of rat prolactin receptor gene expression. J. Biol. Chem., 269,13337-13345.
28. Nicoll, C.S. (1974) Physiological actions of prolactin. In Greep, R.O. and Astwood, E.D. (eds), Handbook of Physiology. Vol 7. American Physiological Society, Washington, D.C., p. 253.
29. Okamura, H., Zachwieja J., Raguet, S. and Kelly, P.A. (1989) Characterization and applications of monoclonal antibodies to the prolactin receptor. Endocrinology, 124, 2499-2508.
30. Quintana, J., Hipkin, R.W., Sánchez-Yague, J. and Ascoli M. (1994) Follitropin (FSH) and a phorbol ester stimulate the phosphorylation of the FSH receptor in intact cells. J. Biol. Chem., 269, 8772-8779.
31. Rillema, J.S., Campbell, G.S., Lawson, D.W. and Carter-Su, C. (1992) Evidence for a rapid stimulation of tyrosine kinase activity by prolactin in Nb2 rat lymphoma. Endocrinology, 131, 973-975.
32. Rui, H., Djeu, T.Y., Evans, C,A. et al. (1992) Prolactin receptor triggering evidence for rapid tyrosine kinase activation. J. Biol. Chem., 267, 24071-24081.
33. Rui, H., Lebrun, J.-J., Kirken, R.A. et al. (1994) JAK2 activation and cell proliferation induced by antibody-mediated prolactin receptor dimerization. Endocrinology, 135, 1299-1306.
34. Russell, D.H. (1989) New aspects of prolactin and immunity: a lymphocyte derived prolactin-like product and nuclear protein kinase C activation. Trends Pharmacol. Sci., 10, 40-44.
35. Sauder, S.E., Frager, M., Case, G.D. et al. (1984) Abnormal patterns of pulsatile luteinizing hormone secretion in women with hyperprolactinemia and amenorrhea: response to bromocriptine. J. Clin. Endocrinol. Metab., 56, 941-948.
36. Shinohara, O., Knecht, M. and Catt, K.J. (1985) Inhibition of gonadotropin-induced granulosa cell differentiation by activation of protein kinase C. Proc. Natl. Acad. Sci. USA, 82, 8518-8522.
37. Sjogren, A., Hillensjo, T., Roos, P. and Hamberger, L. (1988) Prolactin and gonadotrophin interactions on progesterone formation in cultured human granulosa cells. Hum. Reprod., 3, 601-105.
38. Veldhuis, J.D. and Demers, L.M. (1986) An inhibitory role for the protein kinase C pathway in ovarian steroidogenesis. Biochem. J., 239, 505-511.
39. Veldhuis, J.D., Klase, P. and Hammond, J.M. (1980) Divergent effects of prolactin upon steroidogenesis by porcine granulosa cells in vitro: influence of cytodifferentiation. Endocrinology, 107, 42-46.
40. Wang, C., Hsueh, A.J.W. and Erickson, G.F. (1980) Prolactin inhibition of estrogen production by cultured rat granulosa cells. Mol. Cell. Endocrinol., 20, 135-144.
41. Waters, M.J., Daniel, N., Bignon, C. and Djiane J. (1995) The rabbit mammary gland prolactin receptor is tyrosine-phosphorylated in response to prolactin in vitro and in vivo. J. Biol. Chem., 270, 5136-5143.
42. Yu-Lee, L.-Y. (1990) Prolactin stimulates transcription of growth-related genes in Nb2 T lymphoma cells. Mol. Cell. Endocrinol., 68, 21-28.