Design considerations and computer modeling related to the development of molecular scaffolds and peptide mimetics for combinatorial chemistry

Molecular Diversity

Volumn 2, Issue 1-2, 1996, Pages 46-56

  Hruby, Victor J ^a   Shenderovich, Mark ^a   Lam, Kit S ^b   Lebl, Michal ^c,d  

^a University of Arizona   (United States)

^b UNIVERSITY OF ARIZONA   (United States)

^c Selectide Corporation   (United States)

^d Houghten Pharmaceuticals Inc   (United States)

Author keywords

Backbone conformation; Chi space; Scaffold design; Topographical design; Topography

Indexed keywords

BACTERIAL PROTEIN; LIGAND; PEPTIDE; PEPTIDE LIBRARY; STREPTAVIDIN;

ANIMAL; ARTICLE; CHEMICAL STRUCTURE; CHEMISTRY; COMPUTER SIMULATION; DRUG DESIGN; METABOLISM; MOLECULAR MIMICRY; PROTEIN BINDING; PROTEIN CONFORMATION;

ANIMALS; BACTERIAL PROTEINS; COMPUTER SIMULATION; DRUG DESIGN; LIGANDS; MODELS, MOLECULAR; MOLECULAR MIMICRY; PEPTIDE LIBRARY; PEPTIDES; PROTEIN BINDING; PROTEIN CONFORMATION; STREPTAVIDIN;

EID: 0030252581     PISSN: 13811991     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF01718700     Document Type: Article

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