Glycodelin from seminal plasma is a differentially glycosylated form of contraceptive glycodelin-A

Molecular Human Reproduction

Volumn 2, Issue 10, 1996, Pages 759-765

  Koistinen, Hannu ^a   Koistinen, Riitta ^a   Dell, Anne ^b   Morris, Howard R ^b   Easton, Richard L ^b   Patankar, Manish S ^c   Oehninger, Sergio ^c   Clark, Gary F ^c   Seppälä, Markku ^a  

^a HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

^b IMPERIAL COLLEGE LONDON   (United Kingdom)

^c EASTERN VIRGINIA MEDICAL SCHOOL   (United States)

Author keywords

Contraception; Glycodelin; Glycosylation; Lectin; PP14

Indexed keywords

AMIDASE; CARBOHYDRATE; GLYCOPEPTIDASE; GLYCOPROTEIN; LECTIN; N ACETYLGLUCOSAMINE RECEPTOR; PAEP PROTEIN, HUMAN; PLACENTA PROTEIN; PLANT LECTIN; SAMBUCUS NIGRA LECTINS; SIALIDASE; WISTERIA LECTIN;

AMNION FLUID; ARTICLE; CHEMISTRY; CLASSIFICATION; COMPARATIVE STUDY; FEMALE; GLYCOSYLATION; HUMAN; IMMUNOASSAY; ISOELECTRIC FOCUSING; ISOLATION AND PURIFICATION; MALE; METABOLISM; PEPTIDE MAPPING; PREGNANCY; PROTEIN PROCESSING; SPERM;

AMIDOHYDROLASES; AMNIOTIC FLUID; CARBOHYDRATES; FEMALE; GLYCOPROTEINS; GLYCOSYLATION; HUMANS; IMMUNOASSAY; ISOELECTRIC FOCUSING; LECTINS; MALE; NEURAMINIDASE; PEPTIDE MAPPING; PEPTIDE-N4-(N-ACETYL-BETA-GLUCOSAMINYL) ASPARAGINE AMIDASE; PLANT LECTINS; PREGNANCY; PREGNANCY PROTEINS; PROTEIN PROCESSING, POST-TRANSLATIONAL; RECEPTORS, N-ACETYLGLUCOSAMINE; SEMEN;

EID: 0030252456     PISSN: 13609947     EISSN: None     Source Type: Journal    
DOI: 10.1093/molehr/2.10.759     Document Type: Article

References (28)

1. Bolton, A.E., Pockley, A.G., Clogh, K.J. et al. (1987) Identification of placental protein 14 as an immunosuppressive factor in human reproduction. Lancet, i, 593-595.
2. Clark, G.F., Oehninger, S., Patankar, M.S. et al. (1996) A role of glycoconjugates in human development: the human feto-embryonic defense system hypothesis. Hum. Reprod., 11, 467-473.
3. Cleveland, D.W., Fischer, S.G., Kirschner, M.W. et al. (1977) Peptide mapping by limited proteolysis in sodium dodecyl sulfate and analysis by gel electrophoresis. J. Biol. Chem., 252, 1102-1102.
4. Dell, A., Morris, H.R., Easton, R. et al. (1995) Structural analysis of the oligosaccharides associated with glycodelin, a human glycoprotein with potent immunosuppressive and contraceptive activities. J. Biol. Chem., 270, 24116-24126.
5. Grinnell, B.W., Herman, R.B. and Yan, S.B. (1994) Human protein C inhibits selectin-mediated cell adhesion. Glycobiology, 4, 221-225.
6. Julkunen, M., Wahlström, T., Seppälä, M. et al. (1984) Detection and localization of placental protein 14-like protein in human seminal plasma and in the male genital tract. Arch. Androl., 12 (Suppl.), 59-67.
7. Julkunen, M., Koistinen, R., Sjöberg, J. et al. (1986) Secretory endometrium synthesizes placental protein 14. Endocrinology, 118, 1782-1786.
8. Julkunen, M., Seppälä, M. and Jänne, O. (1988) Complete amino acid sequence of human placental protein 14: A progesterone-regulated uterine protein homologous to β-lactoglobulin. Proc. Natl. Acad. Sci. USA, 85, 8845-8849.
9. Julkunen, M., Koistinen, R., Suikkari, A-M. et al. (1990) Identification by hybridization histochemistry of human endometrial cells expressing mRNAs encoding uterine β-lactoglobulin homologue and an insulin-like growth factor-binding protein-1. Mol. Endocrinol., 4, 700-707.
10. Kämäräinen, M., Julkunen, M. and Seppälä M. (1991) HinfI polymorphism in the human progesterone associated endometrial protein (PAEP) gene. Nucleic Acids Res., 19, 5092.
11. Kämäräinen, M., Riittinen, L., Seppälä, M. et al. (1994) Progesterone-associated endometrial protein - a constitutive marker of human erythroid precursors. Blood, 84, 467-473.
12. Khoo, K.-H., Sarda, S., Xu, X. et al. (1995) A unique multifucosylated-3GalNAcβ1→4GlcNAcβ1→3Galα1-motif constitutes the repeating unit of the complex O-glycans derived from the cercarial glycocalyx of Schistosoma mansoni. J. Biol. Chem., 270, 17114-17123.
13. Koistinen, H., Seppälä, M. and Koistinen, R. (1994) Different forms of insulin-like growth factor-binding protein-3 detected in serum and seminal plasma by immunofluorometric assay with monoclonal antibodies. Clin. Chem., 40, 531-536.
14. Krøll, J. (1973) Tandem-crossed immunoelectrophoresis. In Axelsen N.H., Krøll, J. and Weeke, B. (eds), Manual of Quantitative Immunoelectrophoresis, Methods and Applications. Universitetforlaget, Oslo, 57-59.
15. Morris, H.R., Dell, A., Easton, R.L. et al. (1996) Gender specific glycosylation of human glycodelin affects its contraceptive activity. J. Biol. Chem., in press.
16. Morrow, D.M., Xiong, N., Getty, R.R. et al. (1994) Hematopoietic placental protein 14. An immunosuppressive factor in cells of the megakaryocytic lineage. Am. J. Pathol., 145, 1485-1495.
17. Nguyen, V.C., Vaisse, C., Gross, M.-S. et al. (1991) The human placental protein 14 (PP14) gene is localized on chromosome 9q34. Hum. Genet., 86, 515-518.
18. Oehninger, S., Clark, G.F., Acosta, A.A. et al. (1991) Nature of the inhibitory effect of complex saccharides on the tight binding of human spermatozoa to the zona pellucida. Fertil. Steril., 55, 165-169.
19. Oehninger, S., Coddington C.C., Hodgen G.D. et al. (1995) Factors affecting fertilization: endometrial placental protein 14 reduces the capacity of human spermatozoa to bind to the human zona pellucida. Fertil. Steril., 63, 377-383.
20. Okamoto, N., Uchida, A., Takakura, K. et al. (1991) Suppression by human placental protein 14 of natural killer cell activity. Am. J. Reprod. Immunol., 26, 137-142.
21. Pockley, A.G. and Bolton, A.E. (1990) The effect of human placental protein 14 (PP14) on the production of interleukin-1 from mitogenically stimulated mononuclear cell cultures. Immunology, 69, 277-281.
22. Powell, L.D., Jain, R.K., Matta, K.L. et al. (1995) Characterization of sialyloligosaccharide binding by recombinant soluble and native cell-associated CD22. J. Biol. Chem., 270, 7523-7532.
23. Riittinen, L., Julkunen, M., Seppälä, M. et al. (1989) Purification and characterization of endometrial protein PP14 from mid-trimester amniotic fluid. Clin. Chim. Acta, 184, 19-29.
24. Riittinen, L., Närvänen, O., Virtanen, I. et al. (1991) Monoclonal antibodies against endometrial protein PP14 and their use for purification and radioimmunoassay of PP14. J. Immunol. Methods, 136, 85-90.
25. Srivatsan, J., Smith, D.F. and Cummings, R.D. (1992) Schistosoma mansoni synthesizes novel biantennary Asn-linked oligosaccharides containing terminal β-linked N-acetylgalactosamine. Glycobiology, 2, 445-452.
26. Towbin, H., Staehelin, T. and Gordon, J. (1979) Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. Proc. Natl. Acad. Sci. USA, 76, 4350-4354.
27. Vaisse, C., Atger, M., Potier, B. and Milgrom, E. (1990) Human placental protein 14 gene: sequence and characterization of a short duplication. DNA Cell. Biol., 9, 401-413.
28. Wassarman, P.M. (1990) Profile of a mammalian sperm receptor. Development, 108, 1-17.