Glutamate-induced swelling of cultured astrocytes is mediated by metabotropic glutamate receptor

Science in China, Series C: Life Sciences

Volumn 39, Issue 5, 1996, Pages 517-522

  Yuan, Fang ^a   Wang, Tianyou ^a  

^a CAPITAL MEDICAL UNIVERSITY   (China)

Author keywords

Astrocyte; Ca2+; Dantrolene; Glutamate; Swell; trans ACPD

Indexed keywords

1 AMINO 1,3 CYCLOPENTANEDICARBOXYLIC ACID; 1-AMINO-1,3-DICARBOXYCYCLOPENTANE; CYCLOLEUCINE; DANTROLENE; DRUG DERIVATIVE; GLUTAMIC ACID DERIVATIVE; METABOTROPIC RECEPTOR;

ANIMAL; ARTICLE; ASTROCYTE; BRAIN CORTEX; CELL CULTURE; CELL SIZE; CYTOLOGY; DRUG EFFECT; PHYSIOLOGY; RAT; WISTAR RAT;

ANIMALS; ASTROCYTES; CELL SIZE; CELLS, CULTURED; CEREBRAL CORTEX; CYCLOLEUCINE; DANTROLENE; GLUTAMATES; RATS; RATS, WISTAR; RECEPTORS, METABOTROPIC GLUTAMATE;

EID: 0030251865     PISSN: 10069305     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (13)

1. Chan, P. H., Chu, L., Chen, S., Effects of MK-801 on glutamate-induced swelling of astrocytes in primary cell culture, J. Neurosci. Res., 1990, 25: 87.
2. Backus, K. H., Kettenmann, H., Schachner, M., Pharmacological characterization of the glutamate receptor in cultured astrocytes, J. Neurosci. Res., 1989, 22: 274
3. Monaqhan, D. T., Bridges, R. J., Cotman, C. W., The excitatory amino acid receptors: their classes, pharmacology, and distinct properties in the function of central nervous system, Annu. Rev. Pharmacol. Toxicol., 1989, 29: 365.
4. 2+ homeostasis in hippocampal neurons in vitro, Mol. Pharmacol., 1989, 35: 671.
5. Littman, L., Robinson, M. B., The effects of L-glutamate and trans-(±)-1-amino-1, 3-cyclopentanedicarboxylate on phosphoinsitide hydrolysis can be pharmacologically differentiated, J. Neurochem , 1994, 63: 1291.
6. Kletzien, R. F., Pariza, M. W., Becker, J. E. et al., A method using 3-O-methyl-D-glucose and phloretin for the determination of intracellular water space of cells in monolayer culture, Anal. Biochem., 1975, 68: 537.
7. Kimelberg, H. K., Ransom, B. R., Physiological and pathological aspects of astrocytic swelling, in Astrocytes, Cell Biology and Pathology of Astrocytes (eds. Fedoroff, S., Vernadakis, A ), Vol. 3, New York: Academic Press, 1986, 129-166.
8. Hansson, E., Johansson, B. B., Westergren, I. et al., Glutamate-induced swelling of single astroglial cells in primary culture, Neuroscience, 1994, 63: 1057.
9. 2+ waves in astrocytes, Cell Calcium, 1991, 12: 185.
10. Frandsen, A., Schousboe, A., Mobilization of dantrolene-sensitive intracellular calcium pools is involved in the cyclotoxicity induced by quisqualate and N-methyl-D-aspartate but not by 2-amino-3-(3-hydroxy-5-methylisoxazaol-4-yl) propionate and kainate in cultured cerebral cortical neurons, Proc. Natl. Acad. Sci. USA, 1992, 89: 2590.
11. 2+, Neurosci. Lett., 1991, 122: 210.
12. Tsien, R W., Fox, A. P., Hess, P. et al., Multiple types of calcium channel in excitable cells, in Proteins of Excitable Membranes (eds. Hille, E., Fambrough, D.M.), New York: Wiley-Interscience, 1987, 167-187.
13. Hansson, Metabotropic glutamate receptor activation induces astroglial swelling, J. Bio. Chem., 1994, 269: 21955.