Direct, solid phase assembly of dihydropyrroloindole peptides with conjugated oligonucleotides

Bioconjugate Chemistry

Volumn 7, Issue 5, 1996, Pages 564-567

  Lukhtanov, Eugeny A ^a   Kutyavin, Igor V ^a   Meyer, Rich B ^a  

^a Nanogen Inc USA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARBOXYLATION; SYNTHESIS (CHEMICAL);

CARBAMOYL; CONTROLLED PORE GLASS; COOPERATIVITY; DIRECT SYNTHESIS; GROOVE-BINDING; MELTING TRANSITIONS; MINOR GROOVE BINDING AGENT; MINOR GROOVES; OLIGONUCLEOTIDE SYNTHESIS; SOLID-PHASE ASSEMBLIES;

OLIGONUCLEOTIDES;

EID: 0030250935     PISSN: 10431802     EISSN: None     Source Type: Journal    
DOI: 10.1021/bc960041d     Document Type: Article

References (10)

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3. Benimetskaya, L. Z., Bulychev, N. V., Kozionov, A. L., Koshkin, A. A., Lebedev, A. V., Novozhilov, S. Yu., and Stockman, M. I. (1989) Site-specific laser modification (cleavage) of oligonucleotides. Biopolymers 28, 1129.
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6. Lukhtanov, E. A., Kutyavin, I. V., Gamper, H. B., and Meyer, R. B., Jr. (1995) Oligodeoxyribonucleotides with conjugated dihydropyrroloindole oligopeptides: preparation and hybridization properties. Bioconjugate Chem. 6, 418.
7. Boger, D. L., Coleman, R. S., and Invergo, B. J. (1987) Studies on the total synthesis of CC-1065: preparation of a synthetic, simplified 3-carbamoyl-1,2-dihydro-3H-pyrrolo[3,2-e]indole dimer/trimer/tetramer (CDPI dimer/trimer/tetramer) and development of methodology for PDE-I dimer methyl ester formation. J. Org. Chem. 52, 1521.
8. Haralambidis, J., Dunkan, L., Angus, K., and Tregear, G. W. (1990) The synthesis of polyamide-oligonucleotide conjugate molecules. Nucleic Acids Res. 18, 493.
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