Red blood cell spacing in rat coronary capillaries during the cardiac cycle

Microvascular Research

Volumn 52, Issue 2, 1996, Pages 143-156

  Silverman, David A ^a   Rakusan, Karel ^a  

^a UNIVERSITY OF OTTAWA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

AEROBIC METABOLISM; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CAPILLARY FLOW; CELL SELECTION; CONTROLLED STUDY; CORONARY ARTERY BLOOD FLOW; ENDOCARDIUM; ERYTHROCYTE ADHESIVENESS; HEART CYCLE; HEMATOCRIT; MORPHOMETRICS; NONHUMAN; OXYGEN TRANSPORT; PRIORITY JOURNAL; RAT; TISSUE OXYGENATION;

ANIMALIA;

EID: 0030250806     PISSN: 00262862     EISSN: None     Source Type: Journal    
DOI: 10.1006/mvre.1996.0050     Document Type: Article

References (32)

1. Baskurt, O. K., Edremitlioglu, M., and Temiz, A. (1995). Effect of erythrocyte deformability on myocardial hematocrit gradient. Am. J. Physiol. 268, H260-H264.
2. Batra, S., and Rakusan, K. (1992). Capillary length, tortuosity, and spacing in rat myocardium during cardiac cycle. Am. J. Physiol. 263, H1369-H1376.
3. Batra, S., Kuo, C., and Rakusan, K. (1989). Spatial distribution of coronary capillaries: A-V segment staggering. Adv. Exp. Med. Biol. 248, 241-247.
4. Batra, S., Koyama, T., Gao, M., Horimoto, M., and Rakusan, K. (1992). Microvascular geometry of the rat heart arteriolar and venular capillary regions. Jpn. Heart J. 33(6), 817-828.
5. 2 diffusing capacity and resistance to flow in rabbit lungs. J. Appl. Physiol. 78(3), 778-783.
6. Bos, C., Hoofd, L., and Oostendorp, T. (1995). Mathematical model of erythrocytes as point-like sources. Math. Biosci. 125(2), 165-189.
7. Desjardins, C., and Duling, B. R. (1987). Microvessel hematocrit: measurement and implications for capillary oxygen transport. Am. J. Physiol. 252, H494-H503.
8. Desjardins, C., and Duling, B. R. (1990). Heparinase treatment suggests a role for the endothelial cell glycocalyx in regulation of capillary hematocrit. Am. J. Physiol. 258, H647-H654.
9. Eliasen, P., Amtorp, O., Tøndevold, E., and Haunsø, S. (1982). Regional blood flow, microvascular blood content and tissue haematocrit in canine myocardium. Cardiovasc. Res. 16, 593-598.
10. Fahraeus, R. (1928). Die Strömungsverhältnisse und die Verteilung der Blutzellen im Gefässystem. Klin. Wochenschr. 7, 100-106. (Cited in Keller et al., 1994.)
11. Federspiel, W. J., and Popel, A. S. (1986). A theoretical analysis of the effect of the particulate nature of blood on oxygen release in capillaries. Microvasc. Res. 32, 164-189.
12. Federspiel, W. J., and Sarelius, I. H. (1984). An examination of the contribution of red cell spacing to the uniformity of oxygen flux at the capillary wall. Microvasc. Res. 27, 273-285.
13. Fisher, A. J., Schrader, N. W., and Klitzman, B. (1992). Effects of chronic hypoxia on capillary flow and hematocrit in rat skeletal muscle. Am. J. Physiol. 262, H1877-H1883.
14. Goto, M., Flynn, A. E., Doucette, J. W., Jansen, C. M. A., Stork, M. M., Coggins, D. L., Muehrcke, D. D., Husseini, W. K., and Hoffman, J. E. (1991). Cardiac contraction affects deep myocardial vessels predominantly. Am. J. Physiol. 261, H1417-H1429.
15. Groebe, K., and Thews, G. (1989). Effects of red cell spacing and red cell movement upon oxygen release under conditions of maximally working skeletal muscle. Adv. Exp. Med. Biol. 248, 175-185.
16. 2 flux density at coronary capillaries. Am. J. Physiol. 256, H375-H382.
17. 2 sources in a Kroghian cylinder model. Adv. Exp. Med. Biol. 345, 893-900.
18. Keller, M. W., Damon, D. N., and Duling, B. R. (1994). Determination of capillary tube hematocrit during arteriolar microperfusion. Am. J. Physiol. 266, H2229-H2238.
19. Kirk, E. S., and Honig, C. R. (1964a). An experimental and theoretical analysis of myocardial tissue pressure. Am. J. Physiol. 207(2), 361-367.
20. Kirk, E. S., and Honig, C. R. (1964b). Nonuniform distribution of blood flow and gradients of oxygen tension within the heart. Am. J. Physiol. 207(3), 661-668.
21. Klitzman, B., and Duling, B. R. (1979). Microvascular hematocrit and red cell flow in resting and contracting striated muscle. Am. J. Physiol. 237(4), H481-H490.
22. Pries, A. R., Ley, K., and Gaehtgens, P. (1986). Generalization of the Fahraeus principle for microvessel networks. Am. J. Physiol. 251, H1324-H1332.
23. Rakusan, K. (1971). Vascular capacity and hematocrit in experimental cardiomegaly due to aortic constriction in rats. Can. J. Physiol. Pharmacol. 49(9), 819-823.
24. Sarelius, I. H., Damon, D. N., and Duling, B. R. (1981). Microvascular adaptations during maturation of striated muscle. Am. J. Physiol. 241, H317-H324.
25. Silverman, D. A., and Rakusan, K. A method to determine red blood cell spacing in capillaries of rat heart. Adv. Exp. Med. Biol., in press.
26. Smith, R. E., Reynolds, C. J., and Elder, E. A. (1992). The evolution of proteinase substrates with special reference to dipeptidylpeptidase IV. Histochem. J. 24, 637-647.
27. Spotnitz, H. M., Sonnenblick, E. H., and Spiro, D. (1966). Relation of ultrastructure to function in the intact heart: sarcomere structure relative to pressure volume curves of intact left ventricles of dog and cat. Circ. Res. 18, 49-66.
28. Tsai, A. G., and Intaglietta, M. (1989). Local tissue oxygenation during constant red blood cell flux: a discrete source analysis of velocity and hematocrit changes. Microvasc. Res. 37, 308-322.
29. Tsai, A. G., and Intaglietta, M. (1992). Local tissue oxygenation by statistically distributed sources. Microvasc. Res. 44, 200-213.
30. Vetterlein, F., Hemeling, H., Sammler, J., Pethö, A., and Schmidt, G. (1989). Hypoxia-induced acute changes in capillary and fiber density and capillary red cell distribution in the rat heart. Circ. Res. 64, 742-752.
31. Vicaut, E., and Levy, B. I. (1990). Transmural hematocrit gradient in left ventricular myocardia of rats. Am. J. Physiol. 259, H403-H408.
32. Vicaut, E., Hou, X., Decuypère, L., Taccoen, A., and Duvelleroy, M. (1994). Red blood cell aggregation and microcirculation in rat cremaster muscle. Int. J. Microcirc. 14, 14-21.