Polymers as surface-based tethers with photolytic triggers enabling laser-induced release/desorption of covalently bound molecules

Bioconjugate Chemistry

Volumn 7, Issue 5, 1996, Pages 525-528

  Ching, Jesus ^a   Voivodov, Kamen I ^a,b   Hutchens, T William ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b Molecular Analytical Systems Inc ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINES; BIOMOLECULES; BIOPOLYMERS; CHEMICAL MODIFICATION; MACROMOLECULES; PROBES; SURFACE STRUCTURE;

COVALENTLY BOUND MOLECULES; LASER INDUCED; NOVEL DESIGN; POLYMERIC SURFACES; PROBE DEVICES; PYRIDINIUM; STRUCTURE DETERMINATION; SURFACE-BASED; TETHERED MOLECULES; UNCOUPLINGS;

TETHERLINES;

EID: 0030250631     PISSN: 10431802     EISSN: None     Source Type: Journal    
DOI: 10.1021/bc9600426     Document Type: Article

References (10)

1. Hutchens, T. W., and Yip, T. T. (1993) New Desorption Strategies for the Mass Spectrometric Analysis of Macromolecules. Rapid Commun. Mass Spectrom. 7, 576-580.
2. Hutchens, T. W., and Yip T. T. (1994) Affinity Mass Spectrometry: Probe Element Surfaces Enhanced for Affinity Capture (SEAC). Protein Sci. 3 (Suppl. 1), 81 (Abstract 170-S).
3. Hutchens, T. W., and Yip, T. T. (1994) Method and Apparatus for Desorption and Ionization of Analytes. International Patent (PCT) Publication No. WO94/28418.
4. Hutchens, T. W., Ching, J., and Yip, T. T. (1995) Design of Mass Spectrometric Probe Surfaces for Photolabile Attachment and Release. Protein Sci. 4 (Suppl. 2), 99 (Abstract 204-S).
5. Ching, J., Voivodov, K. I., and Hutchens, T. W. (1996) Surface Chemistries Enabling Photo-Induced Uncoupling/ Desorption of Covalently Tethered Biomolecules. J. Org. Chem. 61, 3582-3583.
6. Voivodov, K. I., Ching, J., and Hutchens, T. W. (1996) Surface Arrays of Energy Absorbing Polymers Enabling Covalent Attachment of Biomolecules for Subsequent Laser-Induced Uncoupling/Desorption. Tetrahedron Lett. 37, 5669-5672.
7. Greg, B. A., and Heller, A. (1991) Redox Polymer Films Containing Enzymes. 1. A Redox-Conducting Epoxy Cement: Synthesis, Characterization, and Electrocatalytic Oxidation of Hydroquinone. J. Phys. Chem. 95, 5970-5975.
8. Hutchens, T. W., and Yip, T. T. (1992) Model protein surface domains for the investigation of metal ion-dependent macromolecular interactions and metal ion transfer. Methods (San Diego) 4, 79-96.
9. Egner, B. J., Langley, J. G., and Bradley, M. (1995) Solid Phase Chemistry: Direct Monitoring by Matrix-Assisted Laser Desorption/Ionization Time of Flight Mass Spectrometry. A Tool for Combinatorial Chemistry. J. Org. Chem. 60, 2652-2653.
10. Brummel, C. L., Lee, I. N. W., Zhou, Y., Benkovic, S. J., and Winograd, N. (1994) A Mass Spectrometric Solution to the Address Problem of Combinatorial Libraries, Science 264, 399-401.