The toxicity of silicon carbide whiskers, a review

Journal of Environmental Science and Health - Part A Toxic/Hazardous Substances and Environmental Engineering

Volumn 31, Issue 8, 1996, Pages 2033-2054

  Vaughan, Gerald L ^a   Trently, Sharon A ^a  

^a UNIVERSITY OF TENNESSEE   (United States)

Author keywords

Carborundum; Man made mineral fibers; Silicon carbide

Indexed keywords

CRYSTAL WHISKERS; FIBERS; HEALTH HAZARDS; ONCOLOGY; TOXICITY;

LUNG CANCER; PARTICLE SIZE; PULMONARY PATHOLOGIES; RESPIRATORY DYSFUNCTION;

SILICON CARBIDE;

SILICON CARBIDE; SILICON DIOXIDE; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; ASBESTOSIS; CHEMICAL COMPOSITION; GEOMETRY; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; LUNG TOXICITY; NONHUMAN; OCCUPATIONAL EXPOSURE; PARTICLE SIZE; RESPIRATORY FAILURE;

ANIMALIA;

EID: 0030250575     PISSN: 10934529     EISSN: None     Source Type: Journal    
DOI: 10.1080/10934529609376473     Document Type: Review

References (44)

1. Stanton MF., Layard M. The carcinogenicity of fibrous minerals. In: Proceedings of the Workshop on Asbestos. Definitions and Measurement Methods held at NBS Gaithersburg, MD, July 18-20, 1977, NBS Special Publication 506, 143-151, National Bureau of Standards, Washington, D.C.
2. Stanton MF., Layard M., Tegeris A., Miller E., May M., Morgan E., Smith A. Relation of Particle Dimension to Carcinogenicity in Amphibole Asbestoses and Other Fibrous Minerals. J. Natl. Cancer Inst. 1981; 67(5):965-975.
3. Harington JS. Fiber Carcinogenesis: Epidemiologic Observations and the Stanton Hypothesis. J. Natl. Cancer Inst. 1981; 67(5): 977-988.
4. Hesterberg TW., Ririe DG., Barrett JC., Nettsheim P. Mechanisms of Cytotoxicity of Asbestos Fibres in Rat Tracheal Epithelial Cells in Culture. Toxicology In Vitro 1987; 1(2): 59-65.
5. Timbrell V. Deposition and Retention of Fibers in the Human Lung. Ann. Occup. Hyg. 1982; 26: 347-369.
6. Oehlert GW. A Reanalysis of the Stanton et al. Pleural Sarcoma Data. Environ. Res. 1991; 54: 194-205.
7. Hesterberg TW., Vu V., Chase GR., McConnell EE., Bunn WB., Anderson R. Use of Animal Models to Study Man-Made Fiber Carcinogenesis. Cellular and Molecular Aspects of Fiber Carcinogenesis 1991; 1: 183-205.
8. Pezerat H., Guignard J., Cherrie JW. Man-Made Mineral Fibers and Lung Cancer: An Hypothesis. Toxicol. Ind. Health 1992; 8(1-2): 77-87.
9. Esmen NA., Erdal S. Human Occupational and Nonoccupational Exposure to Fibers. Environ. Health Perspect. 1990; 88:277-286.
10. Lippmann M. Man-Made Mineral Fibers (MMMF): Human Exposures and Health Risk Assessment. Toxicol. Ind. Health 1990; 6(2): 225-246.
11. Asgharian B., Yu CP. Deposition of Inhaled Fibrous Particles in the Human Lung. J. Aerosol Med. 1988; 1: 37-50.
12. Pott F., Problems in Defining Carcinogenic Fibers. Ann. Occup. Hyg. 1987; 31(4B): 799-802.
13. Simonato L., Fletcher AC., Cherrie J., Andersen A., Bertazzi PA., Charney N., Claude J., Dodgson J., Esteve J., Frentzel-Beyme R., Gardner MJ., Jensen O., Olsen J., Saracci R., Teppo L., Westerholm P., Winklemann R., Winter PD., Zocchetti C. Updating Lung Cancer Mortality Among a Cohort of Man-Made Mineral Fibre Production Workers in Seven European Countries. Cancer Lett. 1986; 30: 189-200.
14. Marsh GM., Enterline PE., Stone RA., Henderson VL. Mortality Among a Cohort of US Man-Made Mineral Fiber Workers: 1985 Follow-Up. J. Occup. Med. 1990; 32(7)594-604.
15. Goldsmith JR. Comparative Epidemiology of Men Exposed to Asbestos and Man-Made Mineral Fibers. Amer. J. Ind. Med. 1986; 10: 543-552.
16. Doll R. Symposium on MMMF, Copenhagen, October 1986: Overview and Conclusions. Ann. Occup. Hyg. 1987; 31:805-819.
17. Lippmann M. Effects of Fiber Characteristics on Lung Deposition, Retention, and Disease. Environ. Health Perspect. 1990; 88: 311-317.
18. Saracci R. Man-made Mineral Fibers and Health. Answered and Unanswered Questions. Scand. J. Work Environ. Health 1985; 11(3 spec. no.): 215-222.
19. Miettinen OS., Rossiter CE. Man-Made Mineral Fibers and Lung Cancer.Epidemiologic Evidence Regarding the Casual Hypothesis. Scand. J. Work Environ. Health 1990; 16(4): 221-231.
20. Wheeler CS. Exposure of Man-Made Mineral Fibers: A Summary of Current Animal Data. Toxicol. Ind. Health 1990; 6(2): 293-307.
21. Smith TJ., Hammond SK., Laidlaw F., Fine S. Respiratory Exposure Associated with Silicon Carbide Production: Estimation of Cumulative Exposures for an Epidemiological Study. Br. J. Ind. Med.1984; 41: 100-108.
22. Beaumont GP. Reduction in Airborne Silicon Carbide Whiskers by Process Improvements. Appl. Occup. Environ. Hyg. 1991; 6(7): 598-603.
23. Peters JM., Smith TJ., Berstein L., Wright WE., Hammond SK. Pulmonary Effects of Exposures in Silicon Carbide Manufacturing. Br. J. Ind. Med. 1984; 41:109-115.
24. Gauthier JJ., Ghezzo H., Martin RR. Pneumoniosis Following Carborundum (Silicon Carbide) Exposure. Am. Rev. Respir. Disease 1985; 131(4): A191.
25. Osterman JW., Greaves IA., Smith TJ., Hammond SK., Robins JM., Theriault G. Work-Related Decrement in Pulmonary Function in Silicon Carbide Production Workers. Br. J. Ind. Med. 1989; 46: 708-716.
26. Edling C., Järvholm B., Andersson L., Axelson O. Mortality and Cancer Incidence Among Workers in an Abrasive Manufacturing Industry. Br. J. Ind. Med. 1987; 44:57-59.
27. Bye E., Eduard W., Gjønnes J., Sørbrøden E. Occurrence of Airborne Silicon Carbide Fibers During Industrial Production of Silicon. Scand. J. Work Environ. Health 1985; 11(2) : 111-115.
28. Dufresne A., Perrault G., Sébastien P., Adnot A., Baril M. Morphology and Surface Characteristics of Particulates from Silicon Carbide Industries. Am. Ind. Hyg. Assoc. J. 1987; 48(8): 718-729.
29. Funahashi A., Schuleter DR, Pintar K., Siegesmund KA., Mandel G., Mandel NS. Pneumoconiosis in Workers Exposed to Silicon Carbide. Am. Rev. Respir. Disease 1984; 129:635-640.
30. Gross P., de Treville RTP., Cralley LJ., Davis JMG. Pulmonary Ferruginous Bodies. Arch. Pathol. 1968; 85: 539-546.
31. Massé S., Bégin R., Cantin A. Pathology of Silicon Carbide Pneumoconiosis. Modern Pathol. 1988; 1(2): 104-108.
32. Durand P., Bégin R., Samson L., Cantin A., Massé S., Dufresne A., Pereault G., Laflamme J. Silicon Carbide Pneumoconiosis: A Radiographic Assessment. Am. J. Ind. Med. 1991; 20(1): 37-47.
33. Vaughan GL., Kennedy JR., Trently SA. The Immediate Effects of Silicon Carbide Whiskers Upon Ciliated Tracheal Epithelium. Environ. Res. 1991; 56: 178-185.
34. Lapin CA., Craig DK., Valerio MG., McCandless JB., Bogoroch RA. A Subchronic Inhalation Toxicity Study in Rats Exposed to Silicon Carbide Whiskers. Fund. Appl. Toxicol. 1991; 16: 128-146.
35. Johnson NF., Hoover MD., Thomassen DG., Cheng YS., Dalley A., Brooks AL. In Vitro Activity of Silicon Carbide Whiskers in Comparison to Other Industrial Fibers Using Four Cell Culture Systems. Am. J. Ind. Med. 1992; 21: 807-823.
36. Bégin R., Dufresne A., Cantin A., Massé S., Sébastien P., Perrault G. Carborundum Pneumoconiosis - Fibers in the Mineral Activate Macrophages to Produce Fibroblast Growth Factors and Sustain the Chronic Inflammatory Disease. Chest 1989; 95:842-849.
37. Gross P., de Treville RTP., Cralley LJ., Granquist WT., Pundsack FL. Pulmonary Response to Fibrous Dusts of Diverse Compositions. Am. Ind. Hyg. Assoc. J. 1970; 31(2): 125-132.
38. Vaughan GL., Trently SA., Wilson R. Pulmonary Response, In Vitro, to Silicon Carbide Whiskers. Environ. Res. 1993; 63: 191-201.
39. Lipkin LE. Cellular Effects of Asbestos and Other Fibers: Correlations with In Vivo Induction of Pleural Sarcoma. Environ. Health Perspect. 1980; 34: 91-102.
40. Birchall JD., Stanley DR., Mockford MJ., Pigott GH., Pinto PJ. Toxicity of Silicon Carbide Whiskers. J. Materials Sci. Lett. 1988; 7: 350-352.
41. Vaughan GL, Jordan J., Karr S. The Toxicity, In Vitro, of Silicon Carbide Whiskers. Environ. Res. 1991; 56: 57-67.
42. Vanderláan M., Steele V., Nettesheim P. Increased DNA Content as an Early Marker of Transformation in Carcinogen-Exposed Rat Tracheal Cell Cultures. Carcinogenesis 1983; 1: 721-727.
43. Pott F., Ziem U., Reiffer FJ., Huth F., Ernst H., Mohr U. Carcinogenicity Studies on Fibres, Metal Compounds and Some Other Dusts in Rats. J. Exper. Pathol. 1987; 32: 129-152.
44. Bogroch R., Luck SR. International Conference on Whisker and Fiber-Toughened Ceramics. Workplace Handling Requirements and Procedures for ACMC Silicon Carbide Whiskers Based on a Subchronic Inhalation Study in Rats. Proceedings of a ASTM International Conference, Oak Ridge, TN June 7-9, 1988, 81-89.