메뉴 건너뛰기




Volumn 10, Issue 5, 1996, Pages 379-391

Reproductive effects of chronic administration of murine interferon- gamma

Author keywords

bacterial infections; behavioral development; interferon gamma; male fertility; mice; postnatal development; reproductive toxicity; sexual maturation

Indexed keywords

ANIMALIA; BACTERIA (MICROORGANISMS); MURINAE;

EID: 0030250381     PISSN: 08906238     EISSN: None     Source Type: Journal    
DOI: 10.1016/0890-6238(96)00084-6     Document Type: Article
Times cited : (14)

References (78)
  • 2
    • 0028044062 scopus 로고
    • Cytokines in the treatment of fungal infections
    • 2. Kullberg B, van 't Wout J. Cytokines in the treatment of fungal infections. Biotherapy. 1994;7:195-210.
    • (1994) Biotherapy , vol.7 , pp. 195-210
    • Kullberg, B.1    Van 'T Wout, J.2
  • 3
    • 0028138967 scopus 로고
    • Cytokines and the host defense against Listeria monocytogenes and Salmonella typhimurium
    • 3. Langermans J, van Furth R. Cytokines and the host defense against Listeria monocytogenes and Salmonella typhimurium. Biotherapy. 1994;7:169-78.
    • (1994) Biotherapy , vol.7 , pp. 169-178
    • Langermans, J.1    Van Furth, R.2
  • 4
    • 0027985817 scopus 로고
    • Cytokines in the treatment of leishmaniasis: From studies of immunopathology to patient therapy
    • 4. Ho J, Badaro R, Hatzigeorgiou D, Reed S, Johnson WJ. Cytokines in the treatment of leishmaniasis: From studies of immunopathology to patient therapy. Biotherapy. 1994;7:223-35.
    • (1994) Biotherapy , vol.7 , pp. 223-235
    • Ho, J.1    Badaro, R.2    Hatzigeorgiou, D.3    Reed, S.4    Johnson, W.J.5
  • 5
    • 0024384039 scopus 로고
    • In vivo immune responses to Candida albicans modified by treatment with recombinant murine gamma interferon
    • 5. Garner R. Kurucanti U, Czarniecki C, Chiu H, Domer J. In vivo immune responses to Candida albicans modified by treatment with recombinant murine gamma interferon. Infect Immun. 1989;57: 1800-8.
    • (1989) Infect Immun. , vol.57 , pp. 1800-1808
    • Garner, R.1    Kurucanti, U.2    Czarniecki, C.3    Chiu, H.4    Domer, J.5
  • 6
    • 0028028416 scopus 로고
    • Interferon-gamma and host antimicrobial defense: Current and future clinical applications
    • 6. Murray H. Interferon-gamma and host antimicrobial defense: Current and future clinical applications. Am J Med. 1994;97:459-67.
    • (1994) Am J Med. , vol.97 , pp. 459-467
    • Murray, H.1
  • 7
    • 0023908178 scopus 로고
    • Interferon-gamma, the activated macrophage, and host defense against microbial challenge
    • 7. Murray H. Interferon-gamma, the activated macrophage, and host defense against microbial challenge. Ann Intern Med. 1988;108: 595-608.
    • (1988) Ann Intern Med. , vol.108 , pp. 595-608
    • Murray, H.1
  • 8
    • 0025689946 scopus 로고
    • Gamma interferon, cytokine-induced macrophage activation, and antimicrobial host defense: In vitro, in animal models, and in humans
    • 8. Murray H. Gamma interferon, cytokine-induced macrophage activation, and antimicrobial host defense: In vitro, in animal models, and in humans. Diagn Microbiol Infect Dis. 1990;13:411-21.
    • (1990) Diagn Microbiol Infect Dis. , vol.13 , pp. 411-421
    • Murray, H.1
  • 9
    • 0027222630 scopus 로고
    • Biological basis for the clinical use of interferon
    • 9. Dianzani F. Biological basis for the clinical use of interferon. Gut. 1993;Supplement:S74-S6.
    • (1993) Gut. , Issue.SUPPL.
    • Dianzani, F.1
  • 10
    • 0028097389 scopus 로고
    • The role of cytokines in mycobacterial infection
    • 10. Champsi J, Bermudez L, Young L. The role of cytokines in mycobacterial infection. Biotherapy. 1994;7:187-93.
    • (1994) Biotherapy , vol.7 , pp. 187-193
    • Champsi, J.1    Bermudez, L.2    Young, L.3
  • 11
    • 0024990776 scopus 로고
    • Widespread intradermal accumulation of mononuclear leukocytes in lepromatous leprosy patients treated systemically with recombinant interferon γ
    • 11. Nathan C, Squires K, Griffo W, et al. Widespread intradermal accumulation of mononuclear leukocytes in lepromatous leprosy patients treated systemically with recombinant interferon γ. J Exp Med. 1990;172:1509-12.
    • (1990) J Exp Med. , vol.172 , pp. 1509-1512
    • Nathan, C.1    Squires, K.2    Griffo, W.3
  • 12
    • 0027989603 scopus 로고
    • Successful treatment of refractory visceral leishmaniasis in India using antimony plus interferon-γ
    • 12. Sundar S, Rosenkaimer F, Murray H. Successful treatment of refractory visceral leishmaniasis in India using antimony plus interferon-γ. J Infect Dis. 1994;170:659-62.
    • (1994) J Infect Dis. , vol.170 , pp. 659-662
    • Sundar, S.1    Rosenkaimer, F.2    Murray, H.3
  • 13
    • 0028019691 scopus 로고
    • Cytokines in the treatment of primary immunodeficiency
    • 13. Kruskal B, Ezekowitz R. Cytokines in the treatment of primary immunodeficiency. Biotherapy. 1994;7:249-59.
    • (1994) Biotherapy. , vol.7 , pp. 249-259
    • Kruskal, B.1    Ezekowitz, R.2
  • 14
    • 0024809918 scopus 로고
    • Successful treatment of metastatic renal cell carcinoma with a biologically active dose of recombinant interferon-gamma
    • 14. Aulitzky W, Gastl G, Aulitzky WE, et al. Successful treatment of metastatic renal cell carcinoma with a biologically active dose of recombinant interferon-gamma. J Clin Oncol. 1989;7:1875-84.
    • (1989) J Clin Oncol. , vol.7 , pp. 1875-1884
    • Aulitzky, W.1    Gastl, G.2    Aulitzky, W.E.3
  • 15
    • 0029047151 scopus 로고
    • Long-term treatment of osteopetrosis with recombinant human interferon gamma
    • 15. Key L Jr, Rodriguez R, Willi S. et al. Long-term treatment of osteopetrosis with recombinant human interferon gamma. N Engl J Med. 1995;332:1594-9.
    • (1995) N Engl J Med. , vol.332 , pp. 1594-1599
    • Key L., Jr.1    Rodriguez, R.2    Willi, S.3
  • 16
    • 0023914840 scopus 로고
    • Results of a multicenter placebo-controlled double-blind randomized phase III clinical study of treatment of rheumatoid arthritis with recombinant interferon-gamma
    • 16. Lemmel E, Brackertz D, Franke M, et al. Results of a multicenter placebo-controlled double-blind randomized phase III clinical study of treatment of rheumatoid arthritis with recombinant interferon-gamma. Rheumatol Int. 1988;8:87-93.
    • (1988) Rheumatol Int. , vol.8 , pp. 87-93
    • Lemmel, E.1    Brackertz, D.2    Franke, M.3
  • 17
    • 4243624884 scopus 로고
    • Clinical efficacy of recombinant human interferongamma (rIFN-γ) in chronic granulomatous disease (CGD)
    • 17. Ezekowitz R. Clinical efficacy of recombinant human interferongamma (rIFN-γ) in chronic granulomatous disease (CGD). Clin Res. 1990;38:465A.
    • (1990) Clin Res. , vol.38
    • Ezekowitz, R.1
  • 18
    • 0026527710 scopus 로고
    • Interferon gamma-1b: A review of its pharmacology and therapeutic potential in chronic granulomatous disease
    • 18. Todd PA, Goa KL. Interferon gamma-1b: A review of its pharmacology and therapeutic potential in chronic granulomatous disease. Drugs. 1992;43:111-22.
    • (1992) Drugs , vol.43 , pp. 111-122
    • Todd, P.A.1    Goa, K.L.2
  • 19
    • 0026090433 scopus 로고
    • A controlled trial of interferon gamma to prevent infection in chronic granulomatous disease
    • 19. The International Chronic Granulomatous Disease Cooperative Study Group. A controlled trial of interferon gamma to prevent infection in chronic granulomatous disease. N Engl J Med. 1991; 324:509-16.
    • (1991) N Engl J Med. , vol.324 , pp. 509-516
  • 21
    • 0023034629 scopus 로고
    • A toxicity study of recombinant interferon-gamma given by intravenous infusion to patients with advanced cancer
    • 21. Sriskandan K, Garner P, Watkinson J, et al. A toxicity study of recombinant interferon-gamma given by intravenous infusion to patients with advanced cancer. Cancer Chemother Pharmacol. 1986;18:63-8.
    • (1986) Cancer Chemother Pharmacol. , vol.18 , pp. 63-68
    • Sriskandan, K.1    Garner, P.2    Watkinson, J.3
  • 22
    • 0022632301 scopus 로고
    • The preclinical development of Roferon-A
    • 22. Trown P, Wills R, Kamm J. The preclinical development of Roferon-A. Cancer. 1986;57:1648-56.
    • (1986) Cancer , vol.57 , pp. 1648-1656
    • Trown, P.1    Wills, R.2    Kamm, J.3
  • 23
    • 0006468313 scopus 로고
    • Cloning and expression of murine immune interferon cDNA
    • 23. Gray P, Goeddel D. Cloning and expression of murine immune interferon cDNA. Proc Natl Acad Sci USA. 1983;80:5842-6.
    • (1983) Proc Natl Acad Sci USA , vol.80 , pp. 5842-5846
    • Gray, P.1    Goeddel, D.2
  • 24
    • 0026745932 scopus 로고
    • Utilization of homologous proteins to evaluate the safety of recombinant human proteins-case study: Recombinant human interferon-gamma (rhIFN-γ)
    • 24. Green J, Terrell T. Utilization of homologous proteins to evaluate the safety of recombinant human proteins-case study: Recombinant human interferon-gamma (rhIFN-γ). Toxicol Lett. 1992;64/ 65:321-7.
    • (1992) Toxicol Lett. , vol.64-65 , pp. 321-327
    • Green, J.1    Terrell, T.2
  • 25
    • 0022394512 scopus 로고
    • In vivo augmentation of natural killer activity by combined treatment with recombinant gamma interferon and interleukin-2
    • 25. Shalaby M, Svedersky L, McKay P, Finkle B, Palladino MJ. In vivo augmentation of natural killer activity by combined treatment with recombinant gamma interferon and interleukin-2. J Interferon Res. 1985;5:571-81.
    • (1985) J Interferon Res. , vol.5 , pp. 571-581
    • Shalaby, M.1    Svedersky, L.2    McKay, P.3    Finkle, B.4    Palladino, M.J.5
  • 26
    • 0021928078 scopus 로고
    • Activation of mouse peritoneal macrophages in vitro and in vivo by interferon-γ
    • 26. Murray H, Spitalny G, Nathan C. Activation of mouse peritoneal macrophages in vitro and in vivo by interferon-γ. J Immunol. 1985; 134:1619-22.
    • (1985) J Immunol. , vol.134 , pp. 1619-1622
    • Murray, H.1    Spitalny, G.2    Nathan, C.3
  • 27
    • 0022520058 scopus 로고
    • In vivo activation of macrophages by T cell-derived lymphokines: Killing of tumor cells and schistosomula of Schistosoma mansoni
    • 27. Kubelka C, Ruppel A, Gemsa D. Krammer P. In vivo activation of macrophages by T cell-derived lymphokines: Killing of tumor cells and schistosomula of Schistosoma mansoni. Immunobiol. 1986; 171:311-9.
    • (1986) Immunobiol. , vol.171 , pp. 311-319
    • Kubelka, C.1    Ruppel, A.2    Gemsa, D.3    Krammer, P.4
  • 28
    • 0023093778 scopus 로고
    • In vivo and in vitro activation of alveolar macrophages by recombinant interferon-γ
    • 28. Black C, Catterall J, Remington J. In vivo and in vitro activation of alveolar macrophages by recombinant interferon-γ. J Immunol. 1987;138:491-5.
    • (1987) J Immunol. , vol.138 , pp. 491-495
    • Black, C.1    Catterall, J.2    Remington, J.3
  • 29
    • 0009591992 scopus 로고
    • In vivo and in vitro activation of pulmonary macrophages by IFN-γ for enhanced killing of Paracoccidioides brasiliensis or Blastomyces dermatitidis
    • 29. Brummer E, Hanson L, Restrepo A, Stevens D. In vivo and in vitro activation of pulmonary macrophages by IFN-γ for enhanced killing of Paracoccidioides brasiliensis or Blastomyces dermatitidis. J Immunol. 1988;140:2786-9.
    • (1988) J Immunol. , vol.140 , pp. 2786-2789
    • Brummer, E.1    Hanson, L.2    Restrepo, A.3    Stevens, D.4
  • 30
    • 0011987433 scopus 로고
    • Simulation toxicity study of gene-recombinant-interferon gamma with mice
    • 30. Nomura M, Kakihata K, Ohno H, Fujii F. Onodera T. Simulation toxicity study of gene-recombinant-interferon gamma with mice. Toxicol Lett. 1986;31:44.
    • (1986) Toxicol Lett. , vol.31 , pp. 44
    • Nomura, M.1    Kakihata, K.2    Ohno, H.3    Fujii, F.4    Onodera, T.5
  • 31
    • 0025005423 scopus 로고
    • An animal model for the behavioral effects of interferon
    • 31. Segall MA, Crnic LS. An animal model for the behavioral effects of interferon. Behav Neurosci. 1990;104:612-8.
    • (1990) Behav Neurosci. , vol.104 , pp. 612-618
    • Segall, M.A.1    Crnic, L.S.2
  • 32
    • 0026665157 scopus 로고
    • Behavioral effects of mouse interferons-α and -γ and human interferon-α in mice
    • 32. Crnic L, Segall M. Behavioral effects of mouse interferons-α and -γ and human interferon-α in mice. Brain Res. 1992;590:277-84.
    • (1992) Brain Res. , vol.590 , pp. 277-284
    • Crnic, L.1    Segall, M.2
  • 33
    • 0027751599 scopus 로고
    • Interferon induces sleep and other CNS responses in mice recovering from hexobarbital anesthesia
    • 33. Deloria L, Mannering G. Interferon induces sleep and other CNS responses in mice recovering from hexobarbital anesthesia. Neuropharmacology. 1993;32:1433-6.
    • (1993) Neuropharmacology , vol.32 , pp. 1433-1436
    • Deloria, L.1    Mannering, G.2
  • 34
    • 0025887050 scopus 로고
    • Severe cachexia in mice inoculated with interferon-γ-producing tumor cells
    • 34. Matthys P, Dijkmans R, Proost P, et al. Severe cachexia in mice inoculated with interferon-γ-producing tumor cells. Int J Cancer. 1991;49:77-82.
    • (1991) Int J Cancer , vol.49 , pp. 77-82
    • Matthys, P.1    Dijkmans, R.2    Proost, P.3
  • 35
    • 0011992315 scopus 로고
    • Developmental toxicity evaluation of recombinant human interferon-γ (rhIFN-γ) in the cynomolgus monkey
    • 35. Lewandowski M, Working P, Osterburg I, Vogel F, Korte R, Green J. Developmental toxicity evaluation of recombinant human interferon-γ (rhIFN-γ) in the cynomolgus monkey. Toxicologist. 1991;14:343.
    • (1991) Toxicologist , vol.14 , pp. 343
    • Lewandowski, M.1    Working, P.2    Osterburg, I.3    Vogel, F.4    Korte, R.5    Green, J.6
  • 38
    • 0027067019 scopus 로고
    • Type II interferon may he a potential hazardous therapeutic agent during pregnancy
    • 38. Vassiliadis S, Athanassakis I. Type II interferon may he a potential hazardous therapeutic agent during pregnancy. Br J Haematol. 1992;82:782-3.
    • (1992) Br J Haematol. , vol.82 , pp. 782-783
    • Vassiliadis, S.1    Athanassakis, I.2
  • 39
    • 0026621069 scopus 로고
    • Current guidelines for the preclinical safety assessment of therapeutic proteins
    • 39. Bass R, Kleeberg U, Schroder H, Scheibner E. Current guidelines for the preclinical safety assessment of therapeutic proteins. Toxicol Lett. 1992:64/65:339-47.
    • (1992) Toxicol Lett. , vol.64-65 , pp. 339-347
    • Bass, R.1    Kleeberg, U.2    Schroder, H.3    Scheibner, E.4
  • 40
    • 0029551466 scopus 로고
    • Safety and efficacy of long-term interferon gamma therapy in patients with chronic granulomatous disease
    • 40. Bemiller LS, Roberts DH, Starko KM, Curnutte JT. Safety and efficacy of long-term interferon gamma therapy in patients with chronic granulomatous disease. Blood Cells Molecules Dis. 1995; 21:239-47.
    • (1995) Blood Cells Molecules Dis. , vol.21 , pp. 239-247
    • Bemiller, L.S.1    Roberts, D.H.2    Starko, K.M.3    Curnutte, J.T.4
  • 41
    • 0001734370 scopus 로고
    • Methods for evaluation of rat epididymal sperm morphology
    • Chapin RE, Heindel JJ, eds. New York: Academic Press
    • 41. Filler R. Methods for evaluation of rat epididymal sperm morphology. In: Chapin RE, Heindel JJ, eds. Male reproductive toxicology. New York: Academic Press; 1993:334-43.
    • (1993) Male Reproductive Toxicology , pp. 334-343
    • Filler, R.1
  • 42
    • 0002551961 scopus 로고
    • Bartlett's test of homogeneity of variances
    • San Francisco: W.H. Freeman and Co
    • 42. Sokal R, Rohlf F. Bartlett's test of homogeneity of variances. Biometry. San Francisco: W.H. Freeman and Co., 1969:370-89.
    • (1969) Biometry , pp. 370-389
    • Sokal, R.1    Rohlf, F.2
  • 43
    • 0003052330 scopus 로고
    • Analysis of variance
    • Ames: Iowa State University Press
    • 43. Snedecor G, Cochran W. Analysis of variance. Statistical methods. Ames: Iowa State University Press; 1967:258-75.
    • (1967) Statistical Methods , pp. 258-275
    • Snedecor, G.1    Cochran, W.2
  • 44
    • 0009663357 scopus 로고
    • A multiple comparison procedure for comparing several treatments with a control
    • 44. Dunnett C. A multiple comparison procedure for comparing several treatments with a control. J Am Stat Assoc. 1955;50:1096-129.
    • (1955) J Am Stat Assoc. , vol.50 , pp. 1096-1129
    • Dunnett, C.1
  • 45
    • 84861604521 scopus 로고
    • Multiple comparisons using rank sums
    • 45. Dunn O. Multiple comparisons using rank sums. Technometrics. 1964;6:241-52.
    • (1964) Technometrics , vol.6 , pp. 241-252
    • Dunn, O.1
  • 47
    • 0025281308 scopus 로고
    • Basis and implications of selectively diminished cytokine production in neonatal susceptibility to infection
    • 47. Wilson C, Lewis D. Basis and implications of selectively diminished cytokine production in neonatal susceptibility to infection. Rev Infect Dis. 1990;12:S410-S20.
    • (1990) Rev Infect Dis. , vol.12
    • Wilson, C.1    Lewis, D.2
  • 48
    • 0026635830 scopus 로고
    • Macrophage and lymphocyte functions are downregulated in newborn rabbits
    • 48. Tomai M, Fitzgerald T, Froberg M. Macrophage and lymphocyte functions are downregulated in newborn rabbits, J Leukoc Biol. 1992;51:151-6.
    • (1992) J Leukoc Biol. , vol.51 , pp. 151-156
    • Tomai, M.1    Fitzgerald, T.2    Froberg, M.3
  • 49
    • 0028046708 scopus 로고
    • Development of mucosal immune function in man: Potential for GI disease states
    • 49. Macdonald T. Development of mucosal immune function in man: Potential for GI disease states. Acta Paediatr Jpn. 1994;36:532-6.
    • (1994) Acta Paediatr Jpn. , vol.36 , pp. 532-536
    • Macdonald, T.1
  • 50
    • 0027518495 scopus 로고
    • Modulation of host defenses with interferon-γ in pediatrics
    • 50. Hill H. Modulation of host defenses with interferon-γ in pediatrics. J Infect Dis. 1993;167:S23-S8.
    • (1993) J Infect Dis. , vol.167
    • Hill, H.1
  • 51
    • 0021956725 scopus 로고
    • Impaired production of γ-interferon by newborn cells in vitro is due to a functionally immature macrophage
    • 51. Taylor S, Bryson Y. Impaired production of γ-interferon by newborn cells in vitro is due to a functionally immature macrophage. J Immunol. 1985;134:1493-7.
    • (1985) J Immunol. , vol.134 , pp. 1493-1497
    • Taylor, S.1    Bryson, Y.2
  • 52
    • 0021967551 scopus 로고
    • Defective IFN-γ production in the human neonate. I. Dysregulation rather than intrinsic abnormality
    • 52. Wakasugi N, Virelizier J-L. Defective IFN-γ production in the human neonate. I. Dysregulation rather than intrinsic abnormality. J Immunol. 1985;134:167-71.
    • (1985) J Immunol. , vol.134 , pp. 167-171
    • Wakasugi, N.1    Virelizier, J.-L.2
  • 53
    • 0026029060 scopus 로고
    • Cellular and molecular mechanisms for reduced interleukin-4 and interferon-γ production by neonatal T cells
    • 53. Lewis D, Yu C, Meyer J, English B, Kahn S, Wilson C. Cellular and molecular mechanisms for reduced interleukin-4 and interferon-γ production by neonatal T cells. J Clin Invest. 1991;87:194-202.
    • (1991) J Clin Invest. , vol.87 , pp. 194-202
    • Lewis, D.1    Yu, C.2    Meyer, J.3    English, B.4    Kahn, S.5    Wilson, C.6
  • 54
    • 0022538405 scopus 로고
    • Reduced interferon-gamma mRNA levels in human neonates: Evidence for an intrinsic T cell deficiency independent of other genes involved in T cell activation
    • 54. Lewis D, Larsen A, Wilson C. Reduced interferon-gamma mRNA levels in human neonates: Evidence for an intrinsic T cell deficiency independent of other genes involved in T cell activation. J Exp Med. 1986;163:1018-23.
    • (1986) J Exp Med. , vol.163 , pp. 1018-1023
    • Lewis, D.1    Larsen, A.2    Wilson, C.3
  • 55
    • 0026084879 scopus 로고
    • 1 enhances expression of 50 kDa protein related to 2′-5′ oligoadenylate synthetase in human sperm cells
    • 1 enhances expression of 50 kDa protein related to 2′-5′ oligoadenylate synthetase in human sperm cells. J Cell Physiol. 1991;146:156-63.
    • (1991) J Cell Physiol. , vol.146 , pp. 156-163
    • Naz, R.1    Kumar, R.2
  • 56
    • 0026684085 scopus 로고
    • The lack of effect of tumor necrosis factor-alpha, interleukin-1-alpha, and interferon-gamma on human sperm motility in vitro
    • 56. Haney A, Hughes S, Weinberg J. The lack of effect of tumor necrosis factor-alpha, interleukin-1-alpha, and interferon-gamma on human sperm motility in vitro. J Androl. 1992;13:249-53.
    • (1992) J Androl. , vol.13 , pp. 249-253
    • Haney, A.1    Hughes, S.2    Weinberg, J.3
  • 57
    • 0024444417 scopus 로고
    • Cell-mediated immune responses to sperm antigens: Effects on mouse sperm and embryos
    • 57. Naz R, Mehta K. Cell-mediated immune responses to sperm antigens: Effects on mouse sperm and embryos. Biol Reprod. 1989; 41:533-42.
    • (1989) Biol Reprod. , vol.41 , pp. 533-542
    • Naz, R.1    Mehta, K.2
  • 58
    • 0026834016 scopus 로고
    • Effects of human gamma interferon on mice testis: A quantitative analysis of the spermatogenic cells
    • 58. Kalla N, Mann A, Sharma R, Aulitzky W, Frick J. Effects of human gamma interferon on mice testis: A quantitative analysis of the spermatogenic cells. Acta Eur Fertil. 1992;23:89-94.
    • (1992) Acta Eur Fertil. , vol.23 , pp. 89-94
    • Kalla, N.1    Mann, A.2    Sharma, R.3    Aulitzky, W.4    Frick, J.5
  • 60
    • 0026640793 scopus 로고
    • Direct and indirect effects of murine interleukin-2, gamma interferon, and tumor necrosis factor on testosterone synthesis in mouse Leydig cells
    • 60. Meikle A, de Sousa J, Dacosta N, Bishop D, Samlowski W. Direct and indirect effects of murine interleukin-2, gamma interferon, and tumor necrosis factor on testosterone synthesis in mouse Leydig cells. J Androl. 1992;13:437-43.
    • (1992) J Androl. , vol.13 , pp. 437-443
    • Meikle, A.1    De Sousa, J.2    Dacosta, N.3    Bishop, D.4    Samlowski, W.5
  • 61
    • 0025046555 scopus 로고
    • Differential regulation and expression of major histocompatibility complex (MHC) and Ly-6 gene products on mouse testicular leydig and sertoli cell lines
    • 61. Tokuda N, Kasahara M, Levy R. Differential regulation and expression of major histocompatibility complex (MHC) and Ly-6 gene products on mouse testicular leydig and sertoli cell lines. J Autoimmun. 1990;3:457-71.
    • (1990) J Autoimmun. , vol.3 , pp. 457-471
    • Tokuda, N.1    Kasahara, M.2    Levy, R.3
  • 62
    • 0021879603 scopus 로고
    • Human leukocyte interferon inhibits human chorionic gonadotropin stimulated testosterone production by porcine Leydig cells in culture
    • 62. Orava M, Cantell K, Vihko R. Human leukocyte interferon inhibits human chorionic gonadotropin stimulated testosterone production by porcine Leydig cells in culture. Biochem Biophys Res Commun. 1985;127:809-15.
    • (1985) Biochem Biophys Res Commun. , vol.127 , pp. 809-815
    • Orava, M.1    Cantell, K.2    Vihko, R.3
  • 63
    • 0022474590 scopus 로고
    • Treatment with preparations of human leukocyte interferon decreases serum testosterone
    • 63. Orava M, Cantell K, Vihko R, Treatment with preparations of human leukocyte interferon decreases serum testosterone. Int J Cancer. 1986;38:295-6.
    • (1986) Int J Cancer. , vol.38 , pp. 295-296
    • Orava, M.1    Cantell, K.2    Vihko, R.3
  • 64
    • 0027141147 scopus 로고
    • Murine experimental autoimmune orchitis (EAO) induced by syngeneic testicular germ cells (TC) alone: Orchitogenic and lymphostimulatory activities of TC from mice at various ages
    • 64. Soramoto S, Hiramine C, Takenaka I, HoJo K. Murine experimental autoimmune orchitis (EAO) induced by syngeneic testicular germ cells (TC) alone: Orchitogenic and lymphostimulatory activities of TC from mice at various ages. Clin Immunol Immunopathol. 1993;69:292-9.
    • (1993) Clin Immunol Immunopathol. , vol.69 , pp. 292-299
    • Soramoto, S.1    Hiramine, C.2    Takenaka, I.3    Hojo, K.4
  • 65
    • 0027456835 scopus 로고
    • Adaptive immune responses during murine pregnancy: Pregnancy-induced regulation of lymphokine production by activated T lymphocytes
    • 65. Dudley D, Chen C, Mitchell M, Daynes R, Araneo B. Adaptive immune responses during murine pregnancy: Pregnancy-induced regulation of lymphokine production by activated T lymphocytes. Am J Obstet Gynecol. 1993;168:1155-63.
    • (1993) Am J Obstet Gynecol. , vol.168 , pp. 1155-1163
    • Dudley, D.1    Chen, C.2    Mitchell, M.3    Daynes, R.4    Araneo, B.5
  • 66
    • 0029027923 scopus 로고
    • High numbers of autoantigenreactive mononuclear cells expressing interferon-gamma (IFN-γ), IL-4 and transforming growth factor-beta (TGF-β) are present in cord blood
    • 66. Yu M, Fredrikson S, Link J, Link H. High numbers of autoantigenreactive mononuclear cells expressing interferon-gamma (IFN-γ), IL-4 and transforming growth factor-beta (TGF-β) are present in cord blood. Clin Exp Immunol. 1995;101:190-6.
    • (1995) Clin Exp Immunol. , vol.101 , pp. 190-196
    • Yu, M.1    Fredrikson, S.2    Link, J.3    Link, H.4
  • 68
    • 0027370348 scopus 로고
    • No detection of interferon-γ activity during early pregnancy in the mouse
    • 68. la Bonnardiere C. No detection of Interferon-γ activity during early pregnancy in the mouse. Am J Reprod Immunol. 1993;30:26-31.
    • (1993) Am J Reprod Immunol. , vol.30 , pp. 26-31
    • La Bonnardiere, C.1
  • 69
    • 0028240389 scopus 로고
    • Gestation-related expression of the interferon-γ receptor gene in mouse uterine and embryonic hematopoietic cells
    • 69. Chen H, Kamath R, Pace J, Russell S, Hunt J. Gestation-related expression of the interferon-γ receptor gene in mouse uterine and embryonic hematopoietic cells. J Leukoc Biol. 1994;55:617-25.
    • (1994) J Leukoc Biol. , vol.55 , pp. 617-625
    • Chen, H.1    Kamath, R.2    Pace, J.3    Russell, S.4    Hunt, J.5
  • 70
    • 0028074430 scopus 로고
    • First trimester human trophoblast expresses both interferon-γ and interferon-γ receptor
    • 70. Paulesu L, Romagnoli R, Cintorino M, Ricci M, Garotta G. First trimester human trophoblast expresses both interferon-γ and interferon-γ receptor. J Reprod Immunol. 1994;27:37-48.
    • (1994) J Reprod Immunol. , vol.27 , pp. 37-48
    • Paulesu, L.1    Romagnoli, R.2    Cintorino, M.3    Ricci, M.4    Garotta, G.5
  • 71
    • 0020060102 scopus 로고
    • Serum sex steroid and peptide hormone concentrations, and endometrial estrogen and progestin receptor levels during administration of human leukocyte interferon
    • 71. Kauppila A, Cantell K, Janne O, Kokko E, Vihko R. Serum sex steroid and peptide hormone concentrations, and endometrial estrogen and progestin receptor levels during administration of human leukocyte interferon. Int J Cancer. 1982;29:291-4.
    • (1982) Int J Cancer. , vol.29 , pp. 291-294
    • Kauppila, A.1    Cantell, K.2    Janne, O.3    Kokko, E.4    Vihko, R.5
  • 72
    • 0028803829 scopus 로고
    • Effect of IFN-γ administration in virgin and pregnant mice: Distribution of lymphoid and myeloid cells in the spleen
    • 72. Athanassakis I, Vassiliadis S. Effect of IFN-γ administration in virgin and pregnant mice: Distribution of lymphoid and myeloid cells in the spleen. Eur Cytokine Netw. 1995;6:167-76.
    • (1995) Eur Cytokine Netw. , vol.6 , pp. 167-176
    • Athanassakis, I.1    Vassiliadis, S.2
  • 73
    • 0023199593 scopus 로고
    • Products of activated lymphocytes and macrophages inhibit mouse embryo development in vitro
    • 73. Hill J, Haimovici F, Anderson D. Products of activated lymphocytes and macrophages inhibit mouse embryo development in vitro. J Immunol. 1987;139:2250-4.
    • (1987) J Immunol. , vol.139 , pp. 2250-2254
    • Hill, J.1    Haimovici, F.2    Anderson, D.3
  • 74
    • 0028067281 scopus 로고
    • Synergy of lipopolysaccharide and inflammatory cytokines in murine pregnancy: Alloimmunization prevents abortion but does not affect the induction of preterm delivery
    • 74. Chaouat G. Synergy of lipopolysaccharide and inflammatory cytokines in murine pregnancy: Alloimmunization prevents abortion but does not affect the induction of preterm delivery. Cell Immunol. 1994;157:328-40.
    • (1994) Cell Immunol. , vol.157 , pp. 328-340
    • Chaouat, G.1
  • 75
    • 0026594587 scopus 로고
    • Evidence of embryo-and trophoblast-toxic cellular immune response(s) in women with recurrent spontaneous abortion
    • 75. Hill J, Polgar K, Harlow B, Anderson D. Evidence of embryo-and trophoblast-toxic cellular immune response(s) in women with recurrent spontaneous abortion. Am J Obstet Gynecol. 1992;166: 1044-52.
    • (1992) Am J Obstet Gynecol. , vol.166 , pp. 1044-1052
    • Hill, J.1    Polgar, K.2    Harlow, B.3    Anderson, D.4
  • 76
    • 0026551631 scopus 로고
    • In vivo treatment with interferon-gamma during early pregnancy in mice induces strong expression of major histocompatibility complex class I and II molecules in uterus and decidua but not in extra-embryonic tissues
    • 76. Mattsson R, Mattsson A, Holmdahl R. Scheynius A, Van Der Meide P. In vivo treatment with interferon-gamma during early pregnancy in mice induces strong expression of major histocompatibility complex class I and II molecules in uterus and decidua but not in extra-embryonic tissues. Biol Reprod. 1992;46:1176-86.
    • (1992) Biol Reprod. , vol.46 , pp. 1176-1186
    • Mattsson, R.1    Mattsson, A.2    Holmdahl, R.3    Scheynius, A.4    Van Der Meide, P.5
  • 77
    • 0026033065 scopus 로고
    • Placental MHC class I antigen expression is induced in mice following in vivo treatment with recombinant interferon-gamma
    • 77. Mattsson R, Holmdahl R, Scheynius A, Bernadotte F, Mattsson A, Van der Meide P. Placental MHC class I antigen expression is induced in mice following in vivo treatment with recombinant interferon-gamma. J Reprod Immunol. 1991;19:115-29.
    • (1991) J Reprod Immunol. , vol.19 , pp. 115-129
    • Mattsson, R.1    Holmdahl, R.2    Scheynius, A.3    Bernadotte, F.4    Mattsson, A.5    Van Der Meide, P.6
  • 78
    • 0023847986 scopus 로고
    • Decreased locomotor activity produced by repeated, but not single, administration of murine-recombinant interferon-gamma in mice
    • 78. Weinberger S, Schulteis G, Fernando A, Bakhit C, Martinez JJ. Decreased locomotor activity produced by repeated, but not single, administration of murine-recombinant interferon-gamma in mice. Life Sci. 1988;42:1085-90.
    • (1988) Life Sci. , vol.42 , pp. 1085-1090
    • Weinberger, S.1    Schulteis, G.2    Fernando, A.3    Bakhit, C.4    Martinez, J.J.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.