In vitro determination of antiviral activity of MS8209, a new amphotericin B derivative, against primary isolates of HIV1

Research in Virology

Volumn 147, Issue 5, 1996, Pages 313-318

  Magierowska Jung, M ^a   Cefai D ^b   Marrakchi, H ^c   Chieze, F ^a   Agut, H ^a   Huraux, J M ^a   Seman, M ^c  

^a PITIÉ SALPÊTRIÈRE HOSPITAL   (France)

^b DANA FARBER CANCER INSTITUTE   (United States)

^c UNIVERSITÉ PARIS DESCARTES   (France)

Author keywords

Amphotericin B; Antiviral activity; Derivative MS8209; HIV1; Primary isolates

Indexed keywords

AMPHOTERICIN B DERIVATIVE; ANTIVIRUS AGENT; MS 8209; UNCLASSIFIED DRUG; ZIDOVUDINE;

ANTIVIRAL ACTIVITY; ARTICLE; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1; IN VITRO STUDY; PRIORITY JOURNAL; VIRUS REPLICATION;

HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 0030249882     PISSN: 09232516     EISSN: None     Source Type: Journal    
DOI: 10.1016/0923-2516(96)82289-8     Document Type: Article

References (7)

1. Brun-Vézinet, F., Ingrand, D., Deforges, L., Gochi, K., Perchal, F., Schmitt, M.-P., Jung, M., Masquelier, B., Aubert, J., Buffet-Janvresse, C. & Fleury, H. (1992), HIV-1 sensitivity to zidovudine: a consensus culture technique validated by genotypic analysis of the reverse transcriptase. J. Virol. Meth., 37, 177-188.
2. +cells. AIDS, 5, 1453-1461.
3. De Maimay, R., Adjou, K., Lasmezas, C., Lazarini, F., Seman, M., Deslys, J.P. & ormont, D. (1994), Pharmacological studies of a new derivative of amphotericin B, MS8209, in mouse and hamster scrapie. J. Gen. Virol., 75, 2499-2503.
4. Jung, M., Agut, H., Candotti, D., Ingrand, D., Katlama, C. & Huraux, J.-M. (1992), Susceptibility of HIV-1 isolates to zidovudine: correlation between widely applicable culture test and PCR analysis. J. AIDS, 5, 359-364.
5. Pleskoff, O., Seman, M. & Alizon, M. (1995), Amphotericin B derivative blocks human immunodeficiency virus type 1 entry after CD4 binding: effect on virus-cell fusion but not on cell-cell fusion. J. Virol., 69, 570-574.
6. Saint-Julien, L., Joly, V., Seman, M., Carbon, C. & Yeni, P. (1992), Activity of MS8209, a nonester amphotericin B derivative, in treatment of experimental systemic mycoses. Antimicrob. Agents Chemother., 36, 2722-2728.
7. Schwartz, O., Henin, Y., Maréchal, V. & Montagnier, L. (1988), A rapid and simple colorimetric test for the study of anti-HIV agents. AIDS Res. Hum. Retrovir., 4, 441-448.