Postoperative opioid analgesia: Time for a reconsideration?

Journal of Clinical Anesthesia

Volumn 8, Issue 6, 1996, Pages 441-445

  Kehlet, Henrik ^a   Rung, George W ^b   Callesen, Torben ^b  

^a HVIDOVRE HOSPITAL   (Denmark)

^b NONE

Author keywords

Anesthetics, local; nonsteroidal antiinflammatory drugs; opioid; postoperative pain, side effects

Indexed keywords

MORPHINE; OPIATE;

ANALGESIC ACTIVITY; DOSE RESPONSE; DRUG EFFICACY; GASTROINTESTINAL SYMPTOM; HUMAN; HYPERCAPNIA; HYPOTENSION; HYPOXEMIA; IMMUNOREGULATION; POSTOPERATIVE ANALGESIA; POSTOPERATIVE PAIN; PRIORITY JOURNAL; RESPIRATION DEPRESSION; REVIEW; SEDATION; SOMNOLENCE; TREATMENT PLANNING; URINE RETENTION;

EID: 0030249856     PISSN: 09528180     EISSN: None     Source Type: Journal    
DOI: 10.1016/0952-8180(96)00131-6     Document Type: Article

References (54)

1. 1. Richmond CE, Bromley LM, Woolf CJ: Preoperative morphine pre-empts postoperative pain. Lancet 1993;342(8863):73-5.
2. 2. Katz J, Kavanagh BP, Sandler AN, et al: Preemptive analgesia. Clinical evidence of neuroplasticity contributing to postoperative pain. Anesthesiology 1992;77:739-46.
3. 3. Collis R, Brandner B, Bromley LM, Woolf CJ: Is there any clinical advantage of increasing the pre-emptive dose of morphine or combining pre-incisional with postoperative morphine administration? Br J Anaesth 1995;74:396-9.
4. 4. Kehlet H, Dahl JB: The value of "multi-modal" or "balanced analgesia" in postoperative pain treatment. Anesth Analg 1993;77: 1048-56.
5. 5. Kehlet H, Dahl JB: Preemptive analgesia: its it effective in clinical pain states? In: Gebhart GF (ed): Visceral Pain. (Progress in Pain Research and Management.) Seattle: IASP Press, 1995;5:489-504.
6. 6. Kehlet M, Mather LE (eds): The value of non-steroidal antiinflammatory drugs in postoperative pain. Drugs 1992;44(suppl 5):1-63.
7. 7. Wong HY, Carpenter RL, Kopacz DJ, et al: A randomized, double-blind evaluation of ketorolac tromethamine for postoperative analgesia in ambulatory surgery patients. Anesthesiology 1993;78:6-14.
8. 8. Stahlgren LR, Trierweiler M, Tommeraasen M, et al: Comparison of ketorolac and meperidine in patients with postoperative pain - impact on health care utilization. Clin Ther 1993;15:571-80.
9. 9. Krimmer H, Bruch HP, Hoffman G, Sprotte G, Lloyd J: Comparison of the respiratory effects of ketorolac and morphine in postoperative analgesia. Curr Ther Res 1994;55:1293-303.
10. 10. Power I, Noble DW, Douglas E, Spence AA: Comparison of i.m. ketorolac trometamol and morphine sulphate for pain relief after cholecystectomy. Br J Anaesth 1990;65:448-55.
11. 11. Grass JA, Sakima NT, Valley M, et al: Assessment of ketorolac as an adjuvant to fentanyl patient-controlled epidural analgesia alter radical retropubic prostatectomy. Anesthesiology 1993;78:642-8.
12. 12. Watcha MF, Jones MB, Lagueruela RG, Schweiger C, White PF: Comparison of ketorolac and morphine as adjuvants during pediatric surgery. Anesthesiology 1992;76:368-72.
13. 13. Dahl V, Reader JC, Drøsdal S, Wathne O, Brynildsrud J: Prophylactic oral ibuprofen or ibuprofen-codeine versus placebo for postoperative pain after primary hip arthroplasty. Acta Anaesthesiol Scand 1995;39:323-6.
14. 14. Perttunen K, Kalso K, Heinonen J, Salo J: IV diclofenac in postthoracotomy pain. Br J Anaesth 1992;68:474-80.
15. 15. Varrassi G, Panella L, Piroli A, et al: The effects of perioperative ketorolac infusion on postoperative pain and endocrine-metabolic response. Anesth Analg 1994;78:514-9.
16. 16. Powell H, Smallman JM, Morgan M: Comparison of intramuscular ketorolac and morphine in pain control after laparotomy. Anaesthesia 1990;45:538-42.
17. 17. Ready LB, Brown GR, Stahlgren LH, et al: Evaluation of intravenous ketorolac administered by bolus or infusion for treatment of postoperative pain. A double-blind, placebo-controlled, multicenter study. Anesthesiology 1994;80:1277-86.
18. 18. Fogarty DJ, O'Hanlon JJ, Milligan KR: Intramuscular ketorolac following total hip replacement with spinal anaesthesia and intrathecal morphine. Acta Anaesthesiol Scand 1995;39:191-4.
19. 19. Blackburn A, Stevens JD, Wheatley RG, Madej TH, Hunter D: Balanced analgesia with intravenous ketorolac and patient-controlled morphine following lower abdominal surgery. J Clin Anesth 1995;7:103-8.
20. 20. Fragen RJ, Stulberg SD, Wixson R, Glisson S, Librojo E: Effect of ketorolac tromethamine on bleeding and on requirements for analgesia after total knee arthroplasty. J Bone Joint Surg 1995;77: 998-1002.
21. 21. Parker RK, Holtmann B, Smith I, White PE: Use of ketorolac after lower abdominal surgery. Effect on analgesic requirement and surgical outcome. Anesthesiology 1994;80:6-12.
22. 22. Rosenberg J, Wildschiødtz G, Pedersen MH, von Jessen F, Kehlet H: Late postoperative nocturnal episodic hypoxaemia and associated sleep pattern. Br J Anaesth 1994;72:145-50.
23. 23. Cronin A, Keifer JC, Baghdoyan HA, Lydic R: Opioid inhibition of rapid eye movement sleep by a specific mu receptor agonist. Br J Anaesth 1995;74:188-92.
24. 24. Wahba RW: Perioperative functional residual capacity. Can J Anaesth 1991;38:384-400.
25. 23. Forrest WH, Bellville JW: The effect of sleep plus morphine on the respiratory response to carbon dioxide. Anesthesiology 1964; 25:137-41.
26. 26. Modig J: Respiration and circulation after total hip replacement surgery. A comparison between parenteral analgesics and continuous lumbar epidural block. Acta Anaesthesiol Scand 1976;20: 225-36.
27. 27. Catley DM, Thornton C, Jordan C, Lehane JR, Royston D, Jones JG: Pronounced, episodic oxygen desaturation in the postoperative period: its association with ventilatory pattern and analgesic regimen. Anesthesiology 1985;63:20-8.
28. 28. Delaunay L, Leppert C, Dechaubry V, Levron JC, Liu N, Bonnet F: Epidural clonidine decreases postoperative requirements for epidural fentanyl. Reg Aneasth 1993;18:176-80.
29. 29. Bernard JM, Lagarde D, Souron R: Balanced postoperative analgesia: effect of intravenous clonidine on blood gases and pharmacokinetics of intravenous fentanyl. Anesth Analg 1994;79:1126-32.
30. 30. Andersen R, Krohg K: Pain as a major cause of postoperative nausea. Can Anaesth Soc J 1976;23:366-9.
31. 31. Comroe JH, Dripps RD: Reactions to morphine in ambulatory and bed patients. Surg Gynecol Obstet 1948;87:221-4
32. 32. Weinstein MS, Nicolson SC, Schreiner MS: A single dose of morphine sulfate increases the incidence of vomiting after outpatient inguinal surgery in children. Anesthesiology 1994;81:572-7.
33. 33. Thorén T, Sundberg A, Wattwil M, Garvill JE, Jürgensen U: Effects of epidural bupivacaine and epidural morphine on bowel function and pain after hysterectomy. Acta Anaesthesiol Scand 1989;33:181-5.
34. 34. Yee MK, Evans WD, Facey PE, Haywood MW, Rosen M: Gastric emptying and small bowel transit in male volunteers after i.m. ketorolac and morphine. Br J Anaesth 1991;67:426-31.
35. 35. Petring OU, Dawson PJ, Blake DW, et al: Normal postoperative gastric emptying after orthopaedic surgery with spinal anaesthesia and i.m. ketorolac as the first postoperative analgesia. Br J Anaesth 1995;74:257-60.
36. 36. Nimmo WS, Heading RC, Wilson J, Tothill P, Prescott LF: Inhibition of gastric emptying and drug absorption by narcotic analgesics. Br J Clin Pharmacol 1975;2:509-13.
37. 37. Thörn SF, Wattwil M, Källander A: Effects of epidural morphine and epidural bupivacaine on gastroduodenal motility during the fasted state and after food intake. Acta Anaesthesiol Scand 1994;38: 57-62.
38. 38. Kehlet H: General vs. regional anesthesia. In: Rogers M, Tinker J, Covino B, Longnecker DE (eds): Principals and Practice of Anesthesiology. St. Louis: C.V. Mosby, 1993:1218-34.
39. 39. Liu SS, Carpenter RL, Mackey DC, et al: Effects of perioperative analgesic technique on rate of recovery after colon surgery. Anesthesiology 1995;83:757-65.
40. 40. Jayr C, Thomas H, Rey A, Farhat F, Lasser P, Bourgain JL: Postoperative pulmonary complications. Epidural analgesia using bupivacaine and opioids versus parenteral opioids. Anesthesiology 1993;78:666-76.
41. 41. Seeling W, Bruckmooser KP, Hüfner C, Kneitinger E, Rigg C, Rockemann M: Continuous thoracic epidural analgesia does not diminish postoperative complications after abdominal surgery in patients at risk. Anaesthetist 1990;39:33-40.
42. 42. Dray A: Epidural opiates and urinary retention: new models provide new insights. Anesthesiology 1988;68:323-4.
43. 43. Petros JG, Alameddine F, Testa K, Rimm EB, Robillard KJ: Patient-controlled analgesia and postoperative urinary retention after hysterectomy for benign disease. J Am Coll Surg 1994;179: 663-7.
44. 44. Mangano DT, Siliciano D, Hollenberg M, et al: Postoperative myocardial ischemia. Therapeutic trials using intensive analgesia following surgery. The Study of Perioperative Ischemia (SPI) Research Group. Anesthesiology 1992;76:342-53.
45. 45. Salo M: Effects of anaesthesia and surgery on the immune response. Acta Anaesthesiol Scand 1992;36:201-20.
46. 46. Page GG, Ben-Eliyahu S, Yirmiya R, Liebeskind JC: Morphine attenuates surgery induced enhancement of metastatic colonization in rats. Pain 1993;54:21-8.
47. 47. Yeager MP, Colacchio TA: Effect of morphine on growth of metastatic colon cancer in vivo. Arch Surg 1991;126:454-6.
48. 48. Flores LR, Wahl SM, Rayer BM: Mechanisms of morphine-induced immunosuppression: effect of acute morphine administration on lymphocyte trafficking. J Pharmacol Exp Ther 1995;272: 1246-51.
49. 49. Colacchio TA, Yeager MP, Hildebrandt LW: Perioperative immunomodulation in cancer surgery. Am J Surg 1994;167:174-9.
50. 50. Yeager MP, Colacchio TA, Yu CT, et al: Morphine inhibits spontaneous and cytokine-enhanced natural killer cell cytotoxicity in volunteers. Anesthesiology 1995;83:500-8.
51. 51. Kehlet H: 1993 John J. Bonica Lecture. Postoperative pain relief. A look from the other side. Reg Anesth 1994;19:369-77.
52. 52. Kehlet H: Postoperative pain relief - what is the issue? Br J Anaesth 1994;72:375-8.
53. 53. Bardram L, Funch-Jensen P, Jensen P, Crawford ME, Kehlet H: Recovery after laparoscopic colonic surgery with epidural analgesia and early oral nutrition and mobilisation. Lancet 1995;345 (8952):763-4.
54. 54. Stein C: The control of pain in peripheral tissue by opioids. N Engl J Med 1995;332:1685-90. NSAIDs, hypotension with clonidine, or sensotimotor block with local anesthetics) of doing so.