Evaluation of the calcium-antagonist, antidiarrhoeic and central nervous system activities of Baccharis serraefolia

Journal of Ethnopharmacology

Volumn 53, Issue 3, 1996, Pages 157-163

  Tortoriello, J ^a   Aguilar Santamaria L ^a  

^a INSTITUTO MEXICANO DEL SEGURO SOCIAL   (Mexico)

Author keywords

Baccharis serraefolia; Calcium antagonist; Convulsions; Experimental diarrhoea; Ileum; Intestinal transit

Indexed keywords

ANTIDIARRHEAL AGENT; BACCHARIS SERRAEFOLIA; CALCIUM ANTAGONIST; LOPERAMIDE; NALOXONE; OPIATE RECEPTOR; PENTETRAZOLE; PENTOBARBITAL; PLANT EXTRACT; STRYCHNINE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CALCIUM MOBILIZATION; CALCIUM TRANSPORT; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; CONVULSION; DOSE RESPONSE; DRUG POTENTIATION; GASTROINTESTINAL TRANSIT; GUINEA PIG; ILEUM; INTESTINE TRANSIT TIME; INTRAPERITONEAL DRUG ADMINISTRATION; MALE; MEXICO; MORTALITY; MOUSE; NONHUMAN; ORAL DRUG ADMINISTRATION; SMOOTH MUSCLE CONTRACTION; TONIC SEIZURE; TRADITIONAL MEDICINE;

EID: 0030249106     PISSN: 03788741     EISSN: None     Source Type: Journal    
DOI: 10.1016/0378-8741(96)01438-9     Document Type: Article

References (17)

1. Aguilar-Santamaría, L. and Tortoriello, J. (1996) Anticonvulsant and sedative effects of crude extracts of Ternstroemia pringlei and Ruta chalepensis. Phytotherapy Research (in press).
2. Beubler, E. and Badhri, P. (1990) Comparison of the antisecretory effects of loperamide and loperamide oxide in the jejunum and the colon of rats in-vivo. Journal of Pharmacy and Pharmacology 42, 689-692.
3. Berlin, B., Berlin, E.A., Breedlove, D.E., Duncan, T., Jara, V.M., Laughlin, R.M. and Velasco T. (1990) La herbolaria medico Tzeltal-Tzotzil en los altos de Chiapas. Procomith, Gobierno del Estado de Chiapas, México, pp. 20-24.
4. Bohlmann, F., Zdero, C., King, R.M. and Robinson, H. (1984) A kolavane derivative from Baccharis kingil. Phytochemistry 23, 1511-1512.
5. Elisha, E., Al-Maliki, S.J. and Ibrahem, D.K. (1988) Effects of Jasminum officinale flowers on the central nervous system of the mouse. International Journal of Crude Drug Research 26, 221-227.
6. Kachur, J.F., Morgan, D.W. and Gaginella T.S. (1986) Effect of dextromethorphan on guinea pig ileal contractility in vitro: comparison with levomethorphan, loperamide and codeine. Journal of Pharmacology and Experimental Therapeutics 239, 661-667.
7. Leite, J.R., Carlini, E.A., Lander, N. and Mechoulam, R. (1982) Anticonvulsant effects of the (-) and (+) isomers of cannabidiol and their dimethylheptyl homologs. Pharmacology 24, 141-146.
8. Lozoya, X., Becerril, G. and Martinez, M. (1990) Intraluminal perfusion model of in vitro guinea pig's ileum as a model of study of the antidiarrheic properties of the guava (Psidium guajava). Archivas de Investigation Médica (México) 21, 155-162.
9. Lutterodt, G.D. and Maleque, A. (1988) Effects on mice locomotor activity of a narcotic-like principle from Psidium guajava leaves. Journal of Ethnopharmacology 24, 219-231.
10. Lutterodt, G.D. (1989) Inhibition of gastrointestinal release of acetylcholine by quercetin as a mode of action of Psidium guajava leaf extracts in the treatment of acute diarrhoeal disease. Journal of Ethnopharmacology 25, 235-247.
11. Lutterodt, G.D. (1992) Inhibition of microlax-induced experimental diarrhoea with narcotic-like extracts of Psidium guajava leaf in rats. Journal of Ethnopharmacology 37, 151-157.
12. Morales, M.A., Tortoriello, J., Meckes, M., Paz, D. and Lozoya, X. (1994) Calcium-antagonist effect of quercetin and its relation with the spasmolytic properties of Psidium guajava L. Archives of Medical Research 25, 17-21.
13. Reynolds, I.J., Gould, R.J. and Snyder, S.H. (1984) Loperamide: blockade of calcium channels as a mechanism for antidiarrheal effects. Journal of Pharmacology and Experimental Therapeutics 231, 628-632.
14. Samuelsson G. (1991) Assay for pharmacological activity: non specific assays. In: K. Hostettmann, Assays for Bioactivity, Vol. 6, In: P.M. Dey and J.B. Harborne (Eds.), Methods in Plant Biochemestry, Academic Press, New York.
15. Soicke, H. and Leng-Peschlow, E. (1987) Characterisation of flavonoids from Baccharis trimera and their antihepatotoxic properties. Planta Medica 53, 37-39.
16. Staneva-Stoytcheva, D. and Venkova, K. (1992) Effects of the calcium antagonist diltiazem, verapamil and nitrendipine on the contractile responses of guinea pig isolated ileum to electrical stimulation or carbachol. Journal of Pharmacy and Pharmacology 44, 321-325.
17. Tortoriello, J., Meckes-Fischer, M., Villarreal, M.L., Berlin, B. and Berlin, E.A. (1995) Spasmolytic activity of medicinal plants used to treat gastrointestinal and respiratory diseases in the Highland of Chiapas. Phytomedicine 2, 57-66.