Induction of blocks in nuclear divisions and overcondensation of meiotic chromosomes with cycloheximide during conjugation of Tetrahymena thermophila

Journal of Eukaryotic Microbiology

Volumn 43, Issue 5, 1996, Pages 380-388

  Kaczanowski, Andrzej ^a   Kaczanowska, Janina ^a  

^a UNIVERSITY OF WARSAW   (Poland)

Author keywords

Chromosome condensation; macronuclear retention; meiosis; protein synthesis

Indexed keywords

ANIMALIA; TETRAHYMENA THERMOPHILA;

EID: 0030248848     PISSN: 10665234     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1550-7408.1996.tb05047.x     Document Type: Article

References (54)

1. Allewell, N. M., Oles, J. & Wolfe, J. 1976. A physicochemical analysis of conjugation in Tetrahymena. Exp.Cell Res., 97:394-405.
2. Allis, C. D. & Wiggins, J. C. 1984. Histone rearrangements accompany nuclear differentiation and dedifferentiation in Tetrahymena. Dev. Biol., 101:282-294.
3. Allis, C. D. & Wiggins, J. C. 1984. Proteolytic processing of micronuclear H3 and histone phosphorylation during conjugation in Tetrahymena thermophila. Exp. Cell Res., 53:287-298.
4. Allis, C. D., Colavito-Shepansky, M., & Gorovsky, M A., 1987. Scheduled and unscheduled DNA synthesis during development in conjugating Tetrahymena, Dev. Biol., 124:469-480.
5. Allis, C. D., Allen, R. D., Wiggins, J. C., Chicoine, L. & Richman, R. 1984. Proteolytic processing of H1-like histories in chromatin: a physiologically and developmentally regulated event in Tetrahymena micronuclei. J. Cell Biol., 99:1669-1677.
6. Altshluer, M. J. & Bruns, P. J. 1984. Chromosome designated mutation selection in Tetrahymena thermophila, Genetics, 106:387-401.
7. Andersen, A. H., Christiansen, K., Zechedrich, E. L., Jensen, P. S., Oesheroff, N & Westergaard, O. 1989. Strand specificity of the topoisomerase II mediated-double stranded DNA clevage reaction. Biochemistry, 28:6237-6244.
8. Bischoff, F. R. & Ponstingl, H. 1991. Mitotic regulator protein RCC1 is complexed with a nuclear ras-related polypeptide. Proc. Natl. Acad. Sci. USA, 88:10830-10834.
9. Bruns, P. J. 1986. Genetic organization of Tetrahymena. In: Gall, J .G (ed.), The Molecular Biology of Ciliated Protozoa. Academic Press, New York. Pp. 27-44.
10. Byrne, B. C., Brussard, T. B. & Bruns, P.J. 1978. Induced resistance to 6-methylpurine and cycloheximide in Tetrahymena. I. Germ line mutants of T. thermophila. Genetics, 89:695-702.
11. Darzynkiewicz, Z., Traganos, F., Carter, S. P. & Higgins, P. J. 1987. In situ factors affecting stability of the DNA helix in interphase nuclei and metaphase chromosomes. Exp. Cell Res., 172:168-179.
12. Davis, C. M., Ward, J. G., Herrick, G. & Allis, D. C. 1992. Programmmed nuclear death: apoptotic-like degradation of specific nuclei in conjugating Tetrahymena. Dev. Biol., 154:419-432.
13. Dawe, R. K., Sedat, J. W., Agard, D. A & Cande, Z. 1994. Meiotic chromosome pairing in maize is associated with a novel chromatin organization. Cell, 76:901-912.
14. Doerder, F. P., Frankel, J., Jenkins, L. M. & DeBault, L. E. 1975. Form and pattern in ciliated protozoa: analysis of a genetic mutant with altered cell shape in Tetrahymena pyriformis syngen 1. J. Exp. Zool., 192:237-258.
15. Ernst, S. G. & Oleinick, N. L. 1977. Actinomycin D in Tetrahymena. Nonspecific inhibition of RNA synthesis and primary and secondary effects on protein synthesis. Exp. Cell Res., 110:363-373.
16. Frankel, J. 1969. The relationship of protein synthesis to cell division and oral development in synchronised Tetrahymena pyriformis GL-C: an analysis employing cycloheximide. J. Cell Physiol., 74:135-148.
17. Frankel, J., Jenkins L. M., Doerder, P. M. & Nelsen, E. M. 1976. Mutation affecting cell division. Selection and genetic analysis. Genetic. 83:489-506.
18. Friedl, E., Miyake, A. & Heckmann, K. 1983. Requirements of successive protein synthesis for the progress of meiosis in Blepharisma Exp. Cell Res., 145:105-113.
19. Fulka, J., Jr., Moor, R. M., & Fulka, J. 1994. Sister chromatid separation and the metaphase-anaphase transition in mouse oocytes. Dev. Biol., 165:410-417.
20. Gaertig, J., Seyfert, H. M. & Kaczanowski, A. 1986. Post-meiotic DNA synthesis in nocodazole blocked nuclei during conjugation of Tetrahymena thermophila. Induction of polyploidy in micronucleus. Exp. Cell Res., 164:562-567.
21. Gaertig, J., Kiersnowska, M. & Iftode, F. 1988. Induction of cybrid strains of Tetrahymena by electrofusion. J. Cell Sci., 89:253-261.
22. Gaertig, J. & Fleury, A. 1992. Spatio-temporal reorganization of intracytoplasmic microtubules is associated with nuclear selection of differentiation during the developmental process in the ciliate Tetrahymena thermophila. Protoplasma, 167:74-87.
23. Garfinkel, M. D. & Wolfe, J. 1981. Alteration in gene expression induced by a specific cell interaction during mating in Tetrahymena thermophila. Exp.Cell Res., 133:20 317-324.
24. Guo, X. W., Th'ng, J. P., Swank, R. A., Anderson, H. J., Tudan, C., Bradbury, E. M. & Roberge, M. 1995. Chromosome condensation induced by fostriecin does not require p34 cdc2 kinase activity and histone HI hyperphosphorylation but is associated with histone H2A and H3 phosphorylation. EMBO J., 14:976-985.
25. Hunt, T., Luca, F. C. & Ruderman, J. V. 1992. The requirements for protein synthesis and degradation and the control of destruction of cyclins A and B in the meiotic and mitotic cell cycles in the clam embryo. J. Cell Biol., 116:70-81.
26. Janet, K. J., Messina, L., Erdman, E. B., Arbel, T., & Hawley, R. S. 1995. Induction of metaphase arrest in Drosophila oocytes by chiasma based kinetochore tension. Science, 268:1917-1919.
27. Kaczanowski, A., Gaertig, J. & Kubiak, J. 1985 Effects of antitubuline drug nocodazole on meiosis and postmeiotic development in Tetrahymena thermophila. Induction of achiasmatic meiosis. Exp. Cell Res., 158:244-256.
28. Kaczanowski, A., Gornicka, I. & Cleffmann, G. 1989. Arrest of micronuclear DNA replication during genomic exclusion in Tetrahymena thermophila produces haploid strains. Genetics, 121:37-45.
29. Kaczanowski, A., Ramel, M., Kaczanowska, J. & Wheatley, D. 1991. Macronuclear differentiation in conjugating pairs of Tetrahymena treated with the antitubuline drug nocodazole. Exp. Cell Res., 195:330-337.
30. Kaczanowski, A. 1992 Mutation affecting cell separation and macronuclear resoprtion during conjugation in Tetrahymena thermophila.: early expression of zygotic genotype. Dev. Genet., 13:58-65.
31. Madireddi, M. T., Davis, M. C. & Allis, D. 1994. Identification of a novel polypetide involved in the formation of DNA-containing vesicles during macronuclear development in Tetrahymena. Dev. Biol., 165:418-431.
32. Martindale, D. W., Allis, C. D. & Bruns, P. J. 1982. Conjugation in Tetrahymena thermophila. A temporal analysis of cytological stages. Exp. Cell Res., 140:227-236
33. Martindale, D. W., Allis, C. D. & Bruns, P J 1985. RNA and protein synthesis during meiotic prophase in Tetrahymena thermophila. J. Protozool., 32:644-649.
34. Nanney, D. L., 1953. Nucleocytoplasmic interaction during conjugation in Tetrahymena. Biol. Bull., 105:133-148.
35. Nanney, D. L. 1976. Calcium chloride effects on nuclear development in Tetrahymena. Genet. Res. (Cambridge). 27:297-302.
36. Orias, E. 1986. Ciliate conjugation. In: Gall, J. G, (ed), The Molecular Biology of Ciliated Protozoa. Academic Press, New York. Pp. 45-84.
37. Orias, E. & Bruns, P. J. 1976. Induction and isolation of mutants in Tetrahymena. In: Prescott, D. M. (ed.). Methods in Cell Biology. Academic Press, New York. 13:248-282.
38. Peterson, C. L. 1994. The SMC family: novel motor proteins for chromosome condensation. Cell, 79:389-392.
39. Phillpott, A. & Gregory, H. L. 1991. Sperm decondensation in Xenopus egg cytoplasm is mediated by nucleoplasmin. Cell, 65:569-578.
40. Ray, C., Jr. 1956. Meiosis and nuclear behavior in Tetrahymena pyriformis. J. Protozool, 3:604-610.
41. Resnick, M. A. 1987. Investigating the genetic control of biochemical events in meiotic recombination. In: Moens, P. B. (ed.), Meiosis. Academic Press, New York. Pp. 157-210.
42. Roberts, C. T., Jr. & Orias, E. 1973. Cycloheximide resistant mutant of Tetrahymena pyriformis. Exp. Cell Res. 81:312-316.
43. Roberts, C. T., Jr. & Onas, E. 1974. On the mechanisms of adaptation to protein synthesis inhibitors by Tetrahymena. Facilitation, crossadaptation and sensitization. J. Cell Biol., 62:707-716.
44. Rogers, M. B. & Karrer, K. M. 1989. Cloning of Tetrahymena genomic sequences whose message abundance is increased during conjugation. Dev. Biol., 131:261-268.
45. Stern, H. & Hotta, Y. 1987. The biochemistry of meiosis. In: Moens, P. B. (ed.), Meiosis. Academic Press, New York. Pp. 303-331.
46. Suhr-Jessen, P. B. 1984. Stage specific chnages in protein synthesis during conjugation in Terrahvmena thermophila. Exp. Cell Res., 151:374-383.
47. Sugai, T. & Hiwatashi, K. 1974. Cytologic and autoradiographic studies of the micronucleus at meiotic prophase in Tetrahymena pynformis. J. Protozool., 21:542-548.
48. Szollosi, M. S., Debey, P., Szollosi, D., Rime. H. & Vautier, D. 1991. Chromatin behaviour under the influence of puromycin and 6-DMAP at different stages of mouse oocyte maturation. Chromosoma, 100:339-354.
49. Van Bell, C. T. 1983. An analysis of protein synthesis, membrane proteins and concavalin A-binding proteins during conjugation of Tetrahymena thermophila. Dev. Biol., 98:173-181.
50. Wang, T. & Allis, C. D. 1993 An abundant High-Mobility-Group-like protein is targeted to micronuclei in a cell cycle-dependent and developmentally regulated fashion in Tetrahymena thermophila. Mol. Cell Biol., 13:163-173.
51. Ward, J. G. & Herrick, G. 1996 Effects of the transcription inhibitor actinomycin D on postzygotic development of Tetrahymena thermophila conjugants. Dev. Biol., 173:174-184.
52. Wenkert, D. & Allis, C. D. 1984. Timing of appearance of macronuclear-specific histone variant hv1 and gene expression in developing new macronuclei of Tetrahymena thermophila. J. Cell Biol., 98: 2107-2117.
53. Wolfe, J., Hunter, B. & Adair, W. S. 1976. A cytological study of micronuclear elongation during conjugation in Tetrahymena. Chromosoma, 55:289-308.
54. Yano, J. & Suhama M 1990. Effects of cycloheximide on meiosis and other nuclear changes during conjugation in the ciliate Stylonychia pustulata. J. Sci. Hiroshima Univ. ser. B. div. I, 34:9-28.