The in vitro response to human fibroplast-derived extracellular matrix proteins is restricted by specific HLA class II genes: Relevance for coeliac disease

Human Immunology

Volumn 49, Issue 2, 1996, Pages 106-112

  Jalava, Tarja ^a   Mäki, Markku ^b,d   Marttinen, Aulis ^c   Partanen, Jukka ^a   Koskimies, Saija ^a  

^a FINNISH RED CROSS BLOOD SERVICE   (Finland)

^b UNIVERSITY OF TAMPERE   (Finland)

^c TAMPERE UNIVERSITY OF TECHNOLOGY   (Finland)

^d TAMPERE UNIVERSITY HOSPITAL   (Finland)

Author keywords

[No Author keywords available]

Indexed keywords

HLA ANTIGEN CLASS 2; HLA DQ ANTIGEN; HLA DR3 ANTIGEN; SCLEROPROTEIN;

ARTICLE; CELIAC DISEASE; CONTROLLED STUDY; EXTRACELLULAR MATRIX; FIBROBLAST; HLA SYSTEM; HUMAN; HUMAN CELL; IMMUNOPATHOGENESIS; PRIORITY JOURNAL; SPLEEN CELL;

EID: 0030248482     PISSN: 01988859     EISSN: None     Source Type: Journal    
DOI: 10.1016/0198-8859(96)00043-2     Document Type: Article

References (35)

1. 1. Brandtzaeg P: Immunologic basis for celiac disease, inflammatory bowel disease, and type B chronic gastritis. Curr Opin Gastroenterol 7:450, 1991.
2. 2. Marsh MN: Gluten, major histocompatibility complex, and the small intestine. A molecular and immunobiologic approach to the spectrum of gluten sensivity ("celiac sprue"). Gastroenterology 102:330, 1992.
3. 3. Sollid LM, Markussen G, Ek J, Gjerde H, Vartdal F, Thorsby E: Evidence for a primary association of celiac disease to a particular HLA-DQ α/β heterodimer. J Exp Med 169:345, 1989.
4. 4. Koskimies S, Lipsanen V, Mäki M, Visakorpi J: HLA and coeliac disease, a Finnish family study. In Mearin ML, Mulder CJJ (eds): Coeliac Disease, 40 Years Gluten Free. Dortrecht, Kluwer Academic Publishers, 1991.
5. 5. MacDonald TT, Spencer J: Evidence that activated mucosal T cells play a role in the pathogenesis of enteropathy in the human small intestine. J Exp Med 167:1341, 1988.
6. + lamina propria lymphocytes. Progr Histochem Cytochem 26:201, 1992.
7. 7. Mäki M, Holm K, Lipsanen V, Hällström O, Viander M, Collin P, Savilahti E, Koskimies S: Serological markers and HLA genes among healthy first-degree relatives of patients with coeliac disease. Lancet 338:1350, 1991.
8. 8. Mäki M, Hällström O, Marttinen A: Reaction of human non-collagenous polypeptides with coeliac disease autoantibodies. Lancet 338:724, 1991.
9. 9. Marttinen A, Mäki M: Human fibroblasts synthesize and secrete celiac disease autoantigen molecules. Pediatr Res 34:420, 1993.
10. 10. Holoshitz J, Vila LM, Keroack BJ, McKinley DR, Bayne NK: Dual antigenic recognition by cloned human γδ T cells. J Clin Invest 89:308, 1992.
11. 11. Hoffman RW, Takeda Y, Sharp GC, Lee DR, Hill DL, Kaneoka H, Galdwell CW: Human T cell clones reactive against usmall nuclear ribonucleoprotein autoantigens from connective tissue disease patients and healthy individuals. J Immunol 151:6460, 1993.
12. 12. Lundin KEA, Scott H, Hansen T, et al.: Gliadin-specific, HLA-DQ (α1*0501,β1*0201) restricted T cells isolated from the small intestinal mucosa of cealiac disease patients. J Exp Med 178:187, 1993.
13. 13. Mäki M, Hällström O, Vesikari T, Visakorp JK: Evaluation of a serum IgA class reticulin antibody test for the detection of childhood celiac disease. J Pediatr 105:901, 1984.
14. 14. Hällström O: Comparison of IgA-class reticulin and endomysium antibodies in coeliac disease and dermatitis herpetiformis. Gut 30:1225, 1989.
15. 15. Westman P, Kuismin T, Partanen J, Koskimies S: An HLA-DR typing protocol using group-specific PCR-amplification followed by restriction enzyme digests. Eur J Immunogenet 20:103, 1993.
16. 16. Ota M, Seki T, Nomura N, Sugimura K, Mizuki N, Fukushima H, Tsuji K Inoko H: Modified PCR-RFLP method for HLA-DPB1 and DQA1 genotyping. Tissue Antigens 38:60, 1991.
17. 17. Kimura A, Sasazuki T: Eleventh International Histocompatibility Workshop reference protocol for the HLA DNA-typing technique. In Tsuji K, Aizawa M, Sasazuki T (eds): HLA. Proceedings of the Eleventh International Histocompatibility Workshop and Conference. New York, Oxford University Press, 1992.
18. 18. Mäki M, Holm K, Koskimies S, Hällström O, Visakorpi JK: Normal small bowel biopsy followed by coeliac disease. Arch Dis Child 65:1137, 1990.
19. 19. Collin P, Helin H, Mäki M, Hällström O, Karvonen AL. Follow-up of patients positive in reticulin and gliadin antibody tests with normal small-bowel bipsy. Scand J Gastroenterol 28:595, 1993.
20. 20. Mäki M, Huupponen T, Holm K, Hällström O: Seroconversion of reticulin autoantbodies predicts coeliac disease in insulin-dependent diabetes mellitus. Gut 36:239, 1995.
21. 21. Sikora K, Anand BS, Truelove SC, Ciclitira PJ, Offord RE: Stimulation of lymphocytes from patients with coeliac disease by a subfaction of gluten. Lancet 389, 1976.
22. 22. Cunningham-Rundles S, Cummingham-Rundles C, Pollack MS, Good RA, Dupon B: Response to wheat antigen in in vitro lymphocyte transformation among HLA-B8-positive normal donors. Transplant Proc X:977, 1978.
23. 23. Frew AJ, Bright S, Shewry PR, Munro A: Proliferative response of lymphocytes of normal individuals to wheat proteins (gliadin). Int Arch Allergy Appl Immunol 62: 162, 1980.
24. 24. Scott H, Fausa O, Thorsby E: T-lymphocyte activation by a gluten fraction, glyc-gli. Scand J Immunol 18:185, 1983.
25. 25. Gjerstsen HA, Sollid LM, Ek J, Thorsdy E, Lundin KEA: T cells from the peripheral blood of coeliac disease patients recognize gluten antigens when presented by HLA-DR, -DQ, or -DP molecules. Scand J Immunol 39:567, 1994.
26. 26. Petterson A, Sjöberg K, Lernmark Å, Eriksson S: HLA genotypes in coeliac disease and healthy individuals carrying gliadin antibodies. Eur J Gastroenterol Hepatol 5: 445, 1993.
27. 27. Lundin KEA, Sollid LM, Qvigstad E, Markussen G, Gjertsen HA, Ek J, Thorsby E: T lymphocyte recognition of a celiac disease-associated cis-or trans-encoded HLA-DQα/β heterodimer. J Immunol 145:136, 1990.
28. 28. Kagnoff MF, Harwood JI, Bugawan TL, Erlich HA: Structural analysis of the HLA-DR, -DQ, and -DP alleles on the celiac disease-associated HLA-DR3 (DRw17) haplotype. Proc Natl Acad Sci USA 86:6274, 1989.
29. 29. Gjertsen HA, Lundin KEA, Sollid LM, Eriksen JA, Thorsby E: T cells recognize a peptide derived from α-gliadin presented by the celiac disease associated DQ (α1*0501,β1*0201) heterodimer. Hum Immunol 39: 243, 1994.
30. 30. Buus S, Sette A, Colon SM, Grey HM: Autologous peptides constitutively occupy the antigen binding site on Ia. Science 242:985, 1988.
31. 31. Sette A, Buus S, Appella E, Smith JA, Chesnut R, Miles C, Colon SM, Grey HM: Prediction of major histocompatibility complex binding regions of protein antigens by sequence pattern analysis. Proc Natl Acad Sci USA 86: 3296, 1989.
32. 32. Altmann DM, Sansom D, Marsh SGE: What is the basis for HLA-DQ associations with autoimmune disease? Immunol Today 12:267, 1991.
33. 33. Lundin KEA, Gjetsen HA, Scott H, Sollid LM, Thorsby E: Function of DQ2 and DQ8 as HLA susceptibility molecules in celiac disease. Hum Immunol 41:24, 1994.
34. 34. Lundin KEA, Scott H, Fausa O, Thorsby E, Sollid LM: T cells from the small intestinal mucosa of a DR4,DQ7/DR4, DQ8 celiac disease patient preferentially recognize gliadin when presented by DQ8. Hum Immunol 41:285, 1994.
35. + T cells but no crypt hyperplasia. Scand J Immunol 38:581, 1993.