Transforming activities of human papillomavirus type 59 E5, E6 and E7 open reading frames in mouse C127 cells

Virus Research

Volumn 44, Issue 1, 1996, Pages 57-65

  Rho, Jaerang ^a   De Villiers, Ethel Michele ^b   Choe, Joonho ^a  

^a Korea Advanced Institute of Science and Technology (KAIST)   (South Korea)

^b GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

Author keywords

E5; E6; E7; HPV 59; ORFs; Transformation

Indexed keywords

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL TRANSFORMATION; CYTOMEGALOVIRUS; GENE EXPRESSION; MOUSE; NONHUMAN; OPEN READING FRAME; PLASMID; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SEQUENCE HOMOLOGY; SOUTHERN BLOTTING; UTERINE CERVIX CARCINOMA; VIRUS TRANSFORMATION; WART VIRUS;

ANIMALIA; CYTOMEGALOVIRUS; HUMAN PAPILLOMAVIRUS; HUMAN PAPILLOMAVIRUS TYPE 59; HUMAN PAPILLOMAVIRUS TYPES;

EID: 0030246878     PISSN: 01681702     EISSN: None     Source Type: Journal    
DOI: 10.1016/0168-1702(96)01348-2     Document Type: Article

References (42)

1. Ausubel, F.M., Brent, R., Kingston, R.E., Moore, D.D., Seidman, J.G. Smith, J.A., and Struhl, K. (Eds.) (1990) Current Protocols in Molecular Biology. Wiley Interscience, New York.
2. Bedell, M.A., Jones, K.H., and Laimins, L.A. (1987) The E6-E7 region of human papillomavirus type 18 is sufficient for transformation of NIH 3T3 and Rat-1 cells. J. Virol. 61, 3635-3640.
3. Bedell, M.A., Jones, K.H. Grossman, S.R., and Laimins, L.A. (1989) The identification of human papillomavirus type 18 transforming genes in immortalized and primary cells. J. Virol. 63, 1247-1255.
4. Chan, S.-Y., Delius, H., Halpern, A.L. and Bernard, H.-U. (1995) Analysis of genomic sequences of 95 papillomavirus types uniting typing, phylogeny, and taxonomy. J. Virol. 69, 3074-3083.
5. Chen, S.L. and Mounts, P. (1990) Transforming activity of E5a protein of human papillomavirus type 6 in NIH 3T3 and C127 cells. J. Virol. 64, 3226-3233.
6. Conrad, M., Bubb, V.J. and Schlegel R. (1993) The human papillomavirus type 6 and 16 E5 proteins are membrane-associated proteins which associate with the 16 Kilodalton pore-forming protein. J. Virol. 67, 6170-6178.
7. Conrad, M., Goldstein, D., Andresson, T. and Shlegel, R. (1994) The E5 protein of HPV-6, but not HPV-16, associates efficiently with cellular growth factor receptors. Virology 200, 796-800.
8. de Roda Husman, A.M., Walboomers, J.M., Meijer, C.J., Risse, E.K., Schipper, M.E., Helmerhorst, T.M., Bleker, O.P., Delius, H., van den Brule, A.J. and Snijders, P.J. (1994) Analysis of cytomorphologically abnormal cervical scrapes for the presence of 27 mucosotropic human papillomavirus genotypes, using polymerase chain reaction. Int. J. Cancer 56, 802-806.
9. de Villiers, E.-M. (1989) Heterogeneity of the human papillomavirus group. J. Virol. 63, 4898-4903.
10. de Villiers, E.-M. (1994) Human pathogenic papillomavirus types: An update. In: H. zur Hausen (Ed.), Current Topics in Microbiology and Immunology, Springer Verlag, Berlin, Vo. 186, pp. 1-12.
11. Dvoretzky, I., Shober, R. and Lowy, D. (1980) Focus assay in mouse cells for bovine papillomavirus. Virology 103, 369-375.
12. Dyson, N., Howley, P.M., Munger, K. and Harlow, E. (1989) The human papilloma virus 16 E7 oncoprotein is able to bind to the retinoblastoma gene product. Science 243, 934-937.
13. +-ATPase. Nature 352, 347-349.
14. Halbert, C.L., Demers, G.W. and Galloway, D.A. (1991) The E7 gene of human papillomavirus is sufficient for immortalization of human epithelial cells. J. Virol. 65, 473-478.
15. Hudson, J.B., Bedell, M.A., McCance, D.J. and Laimins, L.A. (1990) Immortalization and altered differentiation of human keratinocytes in vitro by the E6 and E7 open reading frames of human papillomavirus type 18. J. Virol. 64, 519-526.
16. Kaur, P. and McDougall, J.K. (1987) Characterization of primary human keratinocytes transformed by human papillomavirus type 18. J. Virol. 62, 1917-1924.
17. Leechanachai, P., Banks. L., Moreau, F. and Matlashewski, G. (1992) The E5 gene from human papillomavirus type 16 is an oncogene which enhances growth factor - mediated signal transduction to the nucleus. Oncogene 7, 19-25.
18. Leptak, C., Ramon-y-Cajal, S., Kulke, R., Horwitz, B.H., Reise, D.J 2d., Dotto, G.P. and DiMaio, D. (1991) Tumorigenic transformation of murine keratinocytes by the E5 genes of bovine papillomavirus type 1 and human papillomavirus type 16. J. Virol. 65, 7078-7083.
19. Maniatis, T., Fritsch, E.F. and Sambrook, J. (1989) Molecular Cloning: A Laboratory Manual, 2nd edn. Cold Spring Harbor Laboratory, Cold Spring Harbor, N.Y.
20. Mansur, C.P. and Androphy, E.J. (1993) Celluar transformation by papillomavirus oncoproteins. Biochim. Biophys. Acta. 1155, 323-345.
21. Martin, P., Vall, W.C. Schiller, J.T., Lowy, D.R. and Velu, T.J. (1989) The BPV E5 transforming protein can stimulate the transforming activity of EGF and CSF-1 receptors. Cell 59, 21-32.
22. Matsukura, T. and Sugase, M. (1995) Identification of genital human papillomaviruses in cervical biopsy specimens: segregation of specific virus types in specific clinicopathologic lesions. Int. J. Cancer 61, 13-22.
23. Morgan, D., Pecoraro, G., Rosenberg, I. and Defendi, V. (1988) The transformation of C127 mouse fibroblasts by human papillomavirus 16. Cancer Res. 48, 2505-2511.
24. Munger, K., Phelps, W.C., Bubb, V., Howley, P.M. and Schlgel, R. (1989) The E6 and E7 genes of human papillomavirus type 16 together are necessary and sufficient for transformation of primary human keratinocytes. J. Virol. 63, 4417-4421.
25. Oelze, I., Kartenbeck, J., Crusius, K. and Alonso, L. (1995) Human papillomavirus type 16 E5 protein affects cell-cell communication in an epithelial cell line. J. Virol. 69, 4489-4494.
26. Petti, L., Nilson, L. and DiMaio, D. (1994) Specific association between the bovine papillomavirus E5 transformin protein and the b receptor for platelet-derived growth factor in stably transformed and acutely transfected cells. J. Virol. 68, 3582-3592.
27. Pim, D., Collins, M. and Banks, L. (1992) Human Papillomavirus type 16 E5 gene stimulates the transforming activity of the epidermal growth factor receptor. Oncegene 7, 27-32.
28. Pirisi, L., Yasumoto, S., Feller, M., Doniger, J. and Dipaolo, J.A. (1987) Transformation of human fibroblast and keratinocytes with human paillomavirus type 16 DNA. J. Virol. 61, 1061-1066.
29. Rho, J., Park, S.D. and Choe, J. (1993) P3 promoter element of bovine papillomavirus. Cell. Mol. Biol. 39, 205-211.
30. Rho, J., Roy-Burman, A., Kim, H., de Villers, E.-M., Matsukura, T. and Choe, J. (1994) Nucleotide sequence and phylogenetic classification of human papillomavirus type 59. Virology 203, 158-161.
31. Romanczuk, H., Villa, L.L., Schlegel, R. and Howley, P.M. (1991) The viral transcriptional regulatory region upstream of the E6 and E7 genes is a major determinant of the defferential immortalization activities of human papillomavirus types 16 and 18. J. Virol. 64, 2739-2744.
32. Schiller, R., Vass, W, Vousden, K. and Lowy, D. (1986) E5 open reading frame of bovine papillomavirus type 1 encodes a transforming gene. J. Virol. 57, 1-6.
33. Schneider-Gadicke, A. and Schwarz, E. (1986) Different human cervical carcinoma cell lines show similar transcription patterns of human papillomavirus type 18 early genes. EMBO J. 5, 2285-2292.
34. Smotkin, D. and Wettstein, F.O. (1986) Transcription of human papillomavirus type 16 early genes in a cervical cancer and a cancer derived cell line and identification of the E7 protein. Proc. Natl. Acad. Sci. USA 83, 4680-4684
35. Southern, P.J. and Berg, P. (1982) Transformation of mammalian cell to antibiotic resistance with a bacterial gene under control of the SV40 early region promoter. J. Mol. Appl. Genet. 1, 327-341.
36. Storey, A., Osborn, K. and Crawford, L. (1990a) Co-transformation by human paillomavirus types 6 and 11. J. Gen. Virol. 71, 165-171.
37. Storey, A., Almond, N., Osborn, K. and Crawford, L.V. (1990b) Mutations of human papillomavirus type 16 and E7 gene that affect transformation, transactivation and phosphorylation by the E7 protein. J. Gen. Virol. 71, 965-970.
38. Tsunokawa, Y., Takebe, N., Kasamatsu, T., Terada, M. and Sugimura, T. (1986) Transforming activity of human papillomavirus type 16 DNA sequences in a cervical cancer. Proc. Natl. Acad. Sci. USA 83, 2200-2203.
39. Werness, B.A., Levine, A.J. and Howley, P.M. (1990) Association of huamn papillomavirus type 16 and 18 E6 proteins with p53. Science 248, 76-79.
40. Woodworth, C.D., Doniger, J. and DiPaolo, J.A. (1989) Immortalization of human foreskin keratinocytes by various human papillomavirus DNAs corresponds to their association with cervical cancer. J. Virol. 63, 159-164.
41. Yasumoto, S., Burkhardt, A.I., Doniger, J. and Dipaolo, J.A. (1986) Human papillomavirus type 16 DNA-induced malignant transformation of NIH 3T3 cells. J. Virol. 57, 572-577.
42. zur Hausen, H. (1991) Human papillomaviruses in the pathogenesis of anogenital cancer. Virology 184, 9-13.