Activation and desensitisation of aetylcholine release by zinc at Torpedo nerve terminals

Pflugers Archiv European Journal of Physiology

Volumn 432, Issue 5, 1996, Pages 853-858

  Dunant, Yves ^a   Loctin, Françoise ^a   Vallée, Jean Paul ^a   Parducz, Arpad ^b   Lesbats, Bernard ^c   Israël, Maurice ^c  

^a UNIVERSITY OF GENEVA MEDICAL SCHOOL   (Switzerland)

^b INSTITUTE OF EXPERIMENTAL MEDICINE   (Hungary)

^c CNRS   (France)

Author keywords

Acetylcholine release; Calcium; Mediatophore; Synaptic transmission; Synaptosomes; Torpedo electric organ; Zinc

Indexed keywords

CALCIMYCIN; ZINC; ACETYLCHOLINE; CALCIUM; POTASSIUM CHLORIDE; PROTEOLIPID; PROTEOLIPOSOMES;

ACETYLCHOLINE RELEASE; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CALCIUM CURRENT; CONTROLLED STUDY; ELECTRIC ORGAN; FEMALE; IN VITRO STUDY; MALE; NEUROTRANSMISSION; NONHUMAN; PRIORITY JOURNAL; SYNAPTOSOME; ANIMAL; CHOLINERGIC NERVE; DRUG EFFECT; METABOLISM; PHYSIOLOGY; SYNAPTIC TRANSMISSION; TORPEDO;

ACETYLCHOLINE; ANIMALS; CALCIMYCIN; CALCIUM; CHOLINERGIC FIBERS; ELECTRIC ORGAN; FEMALE; MALE; POTASSIUM CHLORIDE; PROTEOLIPIDS; SYNAPTIC TRANSMISSION; SYNAPTOSOMES; TORPEDO; ZINC;

EID: 0030242238     PISSN: 00316768     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004240050208     Document Type: Article

References (26)

1. Babel-Guérin E (1974) Métabolisme du calcium et libération de l'acétylcholine dans l'organe électrique de la Torpille. J Neurochem 23:525-532
2. Benoit PR, Mambrini J (1970) Modification of transmitter release by ions which prolong the presynaptic action potential. J Physiol (Lond) 210:681-695
3. Brochier G, Israël M, Lesbats B (1993) Immunolabelling of the presynaptic membrane of Torpedo electric organ nerve terminals with an antiserum towards the acetylcholine releasing protein mediatophore. Biol Cell 78:145-154
4. Cavalli A, Dunant Y, Leroy C, Meunier FM, Morel N, Israël M (1993) Antisense probes against mediatophore block transmitter release in oocytes primed with neuronal mRNAs. Eur J Neurosci 5:1539-1544
5. Corrèges P, Dunant Y (1996) Disorganisation of quantal acetylcholine release by zinc at the Torpedo nerve-electroplate junction. Pflügers Arch 432:859-866
6. Dunant Y, Israël M (1995) Mediatophore and other presynaptic proteins. A cybernetic linking at the active zone. J Physiol (Paris) 89:147-156
7. Dunant Y, Muller D (1986) Quantal release of acetylcholine evoked by focal depolarisation at the Torpedo nerve-electroplate junction. J Physiol (Lond) 379:461-478
8. Dunant Y, Gautron J, Israël M, Lesbats B, Manaranche R (1972) Les compartiments d'acétylcholine de l'organe électrique de la Torpille et leurs modifications par la stimulation. J Neurochem 19:1987-2002
9. Dunant Y, Loctin F, Marsal J, Muller D, Parducz A, Rabasseda X (1988) Energy metabolism and quantal acetylcholine release. Effects of botulinum toxin, fluorodinitrobenzene and diamide in the Torpedo electric organ. J Neurochem 50:431-439
10. Falk-Vairant J, Corrèges P, Eder-Colli L, Salem N, Meunier F, Lesbats B, Loctin F, Synguelakis M, Israël M, Dunant Y (1996) Evoked acetylcholine release expressed by transfection of mediatophore cDNA. J Neurochem 66:1322-1325
11. Israël M, Lesbats B (1981) Continuous determination by a chemiluminescent method of acetylcholine release and compartmentation in Torpedo electric organ synaptosomes. J Neurochem 37:1475-1483
12. Israël M, Tucek S (1974) Utilisation of acetate and pyruvate for the synthesis of "total", "bound" and "free" acetylcholine in the electric organ of Torpedo. J Neurochem 22:487-491
13. Israël M, Morel N, Lesbals B, Birman S, Manaranche R (1986) Purification of a presynaptic membrane protein that mediates a calcium-dependent translocation of acetylcholine. Proc Natl Acad Sci USA 83:9226-9230
14. Israël M, Meunier FM, Morel N, Leshats B (1987) Calcium-induced desensitization of acetylcholine release from synaptosomes or proteoliposomes equiped with mediatophore, a presynaptic membrane protein. J Neurochem 49:975-982
15. Katz B, Miledi RB (1969) Tetrodotoxin-resistant electric activity in presynaptic terminals. J Physiol (Lond) 203:459-487
16. Lin-Shiau S-Y, Fu WM (1980) Effects of divalent cations on neuromuscular transmission in the chick. Eur J Pharmacol 64: 259-269
17. Morel N, Israël M, Manaranche R, Mastour-Frachon P (1977) Isolation of pure cholinergic nerve endings from Torpedo electric organ. Evaluation of their metabolic properties. J Cell Biol 75:43-55
18. Muller D, Loctin F, Dunant Y (1987) Inhibition of evoked acetylcholine release: two different mechanisms in the Torpedo electric organ. Eur J Pharmacol 133:225-234
19. Nishimura M (1987) Zinc competitively inhibits calcium-dependent release of transmitter at the mouse neuromusculur junction. Pflügers Arch 410:623-626
20. Nishimura M (1988) Zn2+ stimulates spontaneous transmitter release at mouse neuromuscular junctions. Br J Pharmacol 93: 430-436
21. Parducz A, Loctin F, Babel-Guérin E, Dunant Y (1994) Exoendocycytotic images following tetanic stimulation at a cholinergic synapse. A role in calcium extrusion? Neuroscience 62: 93-103
22. Vautrin J, Schaffner AE, Barker JL (1993) Tonic GABA secretion of cultured rat hippocampal neurons rapidly transformed by Zn2+into quantal release. Neurosci Lett 158:125-129
23. Wang YX, Quastel DM (1990) Multiple actions of zinc on transmitter release at mouse end-plates. Pflügers Arch 415: 582-587
24. Xie XM, Smart TG (1991) A physiological role for endogenous zinc in rat hippocampal synaptic neurotransmission. Nature 349:521-524
25. Xie X, Smart TG (1994) Modulation of long-term potentiation in rat hippocampal pyramidal neurons by zinc. Pflügers Arch 427:481-486
26. Zhou FM, Hablitz JJ (1993) Zinc enhances GABAergic transmission in rat neocortical neurons. J Neurophysiol 70: 1264-1269