Platelets and coagulation

Veterinary Clinics of North America - Small Animal Practice

Volumn 26, Issue 5, 1996, Pages 1065-1087

  Boudreaux, Mary K ^a  

^a AUBURN UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INTEGRIN;

ANIMAL; ANIMAL DISEASE; BLOOD; BLOOD CLOTTING; CHEMISTRY; DOG; DOG DISEASE; HEMOPHILIA A; IMMUNOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; REVIEW; THROMBOCYTE; THROMBOCYTOPENIA;

ANIMALS; BLOOD COAGULATION; BLOOD PLATELETS; DOG DISEASES; DOGS; HEMOPHILIA A; INTEGRINS; THROMBOCYTOPENIA;

EID: 0030236301     PISSN: 01955616     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0195-5616(96)50056-2     Document Type: Article

References (161)

1. Alstad AD, Casper HH, Johnson LJ: Vitamin K treatment of sweet clover poisoning in calves. J Am Vet Med Assoc 187:729, 1985
2. Ault KA, Rinder HM, Mitchell J, et al: The significance of platelets with increased RNA content (reticulated platelets): A measure of the rate of thrombopoiesis. Am J Clin Pathol 98:637, 1992
3. Axelrod JH, Read MS, Brinkhous KM, et al: Phenotypic correction of factor IX deficiency in skin fibroblasts of hemophiliac dogs. Proc Natl Acad Sei U S A 87:5173, 1990
4. Balduini CL, Bertolino G, Noris P, et al: Defect of platelet aggregation and adhesion induced by autoantibodies against platelet glycoprotein Ilia. Thromb Haemost 68:208, 1992
5. Bartley TD, Bogenberger J, Hunt P, et al: Identification and cloning of a megakaryocyte growth and development factor that is a ligand for the cytokine receptor Mpl. Cell 77:1117, 1994
6. Bartocci A, Mastrogiannis DS, Migliorati G, et al: Macrophages specifically regulate the concentration of their own growth factor in the circulation. Proc Natl Acad Sei U S A 84:6179, 1987
7. Beck I, Weinmann R, Caro ]: Characterization of hypoxia-responsive enhancer in the human erythropoietin gene shows presence of hypoxia-inducible 120-kD nuclear DNA-binding protein in erythropoietin-producing and nonproducing cells. Blood 82:704, 1993
8. Berkman N, Michaeli Y, Or R, et al: EDTA-dependent pseudothrombocytopenia: A clinical study of 18 patients and a review of the literature. Am J Hematol 36:195, 1991
9. Bevers EM, Comrurius P, Van Rijn JLML, et al: Generation of prothrombin-converting activity and the exposure of phosphatidylserine at the outer surface of platelets. Eur J Biochem 122:429, 1982
10. Beviglia L, Stewart GJ, Niewiarowski S: Effect of four disintegrins on the adhesive and metastatic properties of B16F10 melanoma cells in a murine model. Oncol Res 7:7, 1995
11. Billroth T: Lectures on Surgical Pathology and Therapeutics: A Handbook for Students and Practitioners. London, 1878, p 355
12. Blanchard KL, Acquaviva AM, Galson DL, et al: Hypoxie induction of the human erythropoietin gene: Cooperation between the promoter and enhancer, each of which contains steroid receptor response elements. Mol Cell Biol 12:5373, 1992
13. Boudreaux MK, Dodds WJ, Slauson DO, et al: Impaired cAMP metabolism associated with abnormal function of thrombopathic canine platelets. Biochem Biophys Res Commun 140:595, 1986
14. Boudreaux MK, Crager C, Dillon AR, et al: Identification of an intrinsic platelet function defect in Spitz dogs. J Vet Intern Med 8:93, 1994
15. Boudreaux MK, Panangala VS, Bourne C: A platelet activation-specific monoclonal antibody that recognizes a receptor-induced binding site on canine fibrinogen. Vet Pathol, in press
16. Boudreaux MK, Kvam K, Dillon AR, et al: Type I Glanzmann's thrombasthenia in a Great Pyrenees Dog. Vet Pathol, in press
17. Boukerche H, Berthier-Vergnes O, Bailly M, et al: A monoclonal antibody (LYP18) directed against the blood platelet glycoprotein Ilb/IIIa complex inhibits human melanoma growth in vivo. Blood 74:909, 1989
18. Bray PF: Inherited diseases of platelet glycoproteins: Considerations for rapid molecular characterization. Thromb Haemost 72:492, 1994
19. Brooks PC, Montgomery AMP, Rosenfeld M, et al: Integrin aβ3 antagonists promote tumor regression by inducing apoptosis of angiogenic blood vessels. Cell 79:1157, 1994
20. Broudy VC, Kaushansky K: Thrombopoietin, the c-mpl ligand, is a major regulator of platelet production. J Leukoc Biol 57:719, 1995
21. Broze GJ: Tissue factor pathway inhibitor and the revised theory of coagulation. Annu Rev Med 46:103, 1995
22. Bunch SE, Metcalf MR, Crane SW, et al: Idiopathic pleural effusion and pulmonary thromboembolism in a dog with autoimmune hemolytic anemia. ) Am Vet Med Assoc 195:1748, 1989
23. Cadroy Y, Hanson SR, Kelly AB, et al: Relative antithrombotic effects of monoclonal antibodies targeting different platelet glycoprotein-adhesive molecule interactions in nonhuman primates. Blood 83:3218, 1994
24. Casonato A, Bertomoro A, Pontara E, et al: EDTA-dependent pseudothrombocytopenia caused by antibodies against the cytoadhesive receptor of platelet GP IJb-IIIa. ] Clin Pathol 47:625, 1994
25. Catalfamo JL, Raymond SL, White JG, et at: Defective platelet-fibrinogen interaction in hereditary canine thrombopathia. Blood 67:1568, 1986
26. Cavanaugh PG, Sloane BF, Bajkowski AS, et al: Purification and characterization of platelet aggregating activity from tumor cells: Copurification with procoagulant activity. Thromb Res 37:309, 1985
27. Chelladurai M, Honn KV, Walz DA: HLA-DR is a procoagulant. Biochem Biophys Res Commun 178:467, 1991
28. Coburn J, Barthold SW, Leong JM: Diverse Lyme disease spirochetes bind integrin dinβ, on human platelets. Infect Immun 62:5559, 1994
29. Coller BS, Folts JD, Smith SR, et al: Abolition of in vivo platelet thrombus formation in primates with monoclonal antibodies to the platelet GPIIb/IIIa receptor. Circulation 80:1766, 1989
30. Connelly S, Mount J, Mauser A, et al: Complete correction of canine hemophilia A by in vivo gene therapy, unpublished data
31. Cook NS, Bruttger O, Pally C, et al: The effects of two synthetic glycoprotein Ilb/lIIa antagonists, Ro 43-8857 and L-700,462, on platelet aggregation and bleeding in guinea pigs and dogs: Evidence that Ro 43-8857 is orally active. Thromb Haemost 70:838,1993
32. Creasey AA, Chang AC, Feigen L, et al: Tissue factor pathway inhibitor reduces mortality from £. coli septic shock. J Clin Invest 91:2850, 1993
33. Curtis BR, McFarland JG, Wu GG, et al: Antibodies in sulfonamide-induced immune thrombocytopenia recognize calcium-dependent epitopes on the glycoprotein Ilb/IIIa complex. Blood 84:176, 1994
34. Davis LE: Vitamin K and its therapeutic importance. J Am Vet Med Assoc 180:1354, 1982
35. Day KC, Hoffman LC, Palmier MO, et al: Recombinant lipoprotein-associated coagulation inhibitor inhibits tissue thromboplastin-induced intravascular coagulation in the rabbit. Blood 76:1538, 1990
36. Deckmyn H, Chew SL, Vermylen J: Lack of platelet response to collagen associated with an autoantibody against glycoprotein la: A novel cause of acquired qualitative platelet dysfunction. Thromb Haemost 64:74, 1990
37. DeSauvage FJ, Hass PE, Spencer SD, et al: Stimulation of megakaryocytopoiesis and thrombopoiesis by the c-Mpl ligand. Nature 369:533, 1994
38. DiMinno G, Thiagarajan P, Perussia B, et al: Exposure of platelet fibrinogen-binding sites by collagen, arachidonic acid, and ADP: Inhibition by a monoclonal antibody to the glycoprotein Ilb-IIla complex. Blood 61:140, 1983
39. Dore M, Hawkins HK, Entman ML, et al: Production of a monoclonal antibody against canine GMP-140 (P-selectin) and studies of its vascular distribution in dog tissues. Vet Pathol 30:213, 1993
40. Dore M, Korthuis RJ, Granger DN, et al: P-Selectin mediates spontaneous leukocyte rolling in vivo. Blood 82:1308, 1993
41. Dore M, Simon SI, Hughes BJ, et al: P-selectin and CDlS-mediated recruitment of canine neutrophils under conditions of shear stress. Vet Pathol 32:258, 1995
42. Eisensmith RC, Fang B, Kay MA, et al: Gene therapy for hemophilia B: Cyclosporin treatment increases the persistence of adenovirus-mediated factor IX expression in hemophilia B dogs [abstractJ. Blood 84:255a, 1994
43. Evans JP, Brinkhous KM, Brayer GD, et al: Canine hemophilia B resulting from a point mutation with unusual consequences. Proc Natl Acad Sei U S A 86:10095, 1989
44. Falanga A, Gordon SG: Isolation and characterization of cancer procoagulant: A cysteine proteinase from malignant tissue. Biochemistry 24:5558, 1985
45. Ferroni P, Lenti L, Guadagni F, et al: Possible involvement of tumour cell membrane gangliosides in platelet-tumour cell interactions. Eur J Cancer 31A:79, 1995
46. Fleck RA, Rapaport SI, Rao LV: Anti-prothrombin antibodies and the lupus anticoagulant. Blood 72:512, 1988
47. Frelinger AL III, Cohen I, Plow EF, et al: Selective inhibition of integrin function by antibodies specific for ligand-occupied receptor conformers. J Biol Chem 265:63461990
48. Gasic GJ, Gasic TB: Removal of sialic acid from the cell coat in tumor cells and vascular endothelium and its effects on metastasis. Proc Natl Acad Sei U S A 48:1172, 1962
49. Gasic GJ, Gasic TB, Stewart CC: Antimetastatic effects associated with platelet reduction. Proc Natl Acad Sei U S A 61:46, 1968
50. Giannelli F, Green PM, Sommer SS, et al: Haemophilia B: Database of point mutations and short additions and deletions, fifth edition, 1994. Nucleic Acids Res 22:3534, 1994
51. Giger U, Callan MB, Phillips DK, et al: Inherited platelet 8-storage pool disease in dogs causing severe bleeding: An animal model [abstractJ. Blood 82:164a, 1993
52. Ginsberg MH, Frelinger AL, Lam SCT, et al: Analysis of platelet aggregation disorders based on flow cytometric analysis of membrane glycoprotein Ilb-IHa with conformation-specific monoclonal antibodies. Blood 76:2017, 1990
53. Girard T, Gailani D, Welsch D, et al: Complementary DNA sequencing of canine tissue factor pathway inhibitor reveals the presence of a unique repetitive nanomeric amino acid sequence [abstractJ. Blood 80:263a, 1992
54. Gorelik E, Bere WW, Herberman RB: Role of NK cells in the metastatic effect of anticoagulant drugs. Int J Cancer 33:87, 1984
55. Gowland E, Kay HEM, Spillman JC, et al: Agglutination of platelets by a serum factor in the presence of EDTA. ] Clin Pathol 22:460, 1969
56. Grignani G, Jamison GA: Tissue factor-dependent activation of platelets by cells and microvessels of SK-05-10 human osteogenic sarcoma cell line. Invasion Metastasis 7:172, 1987
57. Gurney AL, Carver-Moore K, de Sauvage FJ, et al: Thrombocytopenia in c-mpldefkient mice. Science 265:1445, 1994
58. Heidenreich R, Eisman R, Surrey S, et al: Organization of the gene for platelet glycoprotein lib. Biochemistry 29:1232, 1990
59. Heilmann E, Friese P, Anderson S, et al: Biotinylated platelets: A new approach to the measurement of platelet life span. Br J Haematol 85:729, 1993
60. Hinchcliff KW, Kociba GJ, Mitten LA: Diagnosis of EDTA-dependent pseudothrombocytopenia in a horse. J Am Vet Med Assoc 203:1715, 1993
61. Hoffman M, Monroe DM, Roberts HR: Coagulation factor IXa binding to activated platelets and platelet-derived microparticles: A flow cytometric study. Thromb Haemost 68:74, 1992
62. Horrn KV, Grossi IM, Diglio CA: Enhanced tumor cell adhesion to the subendothelial matrix resulting from 12(S)-HETE-induced endothelial cell retraction. FASEB J 3:2285, 1989
63. Honn KV, Tang DG, Chen YQ: Platelets and cancer metastasis: More than an epiphenomenon. Semin Thromb Hemost 18:392, 1992
64. Janes SL, Goodall AH: Flow cytometric detection of circulating activated platelets and platelet hyperresponsiveness in pre-eclampsia and pregnancy. Clin Sei 86:731, 1994
65. Johnstone IB, Lotz F: An inherited platelet function defect in Basset hounds. Can Vet J 20:211, 1979
66. Kaushansky K, Lok S, Holly RD, et al: Promotion of megakaryocyte progenitor expansion and differentiation by the c-Mpl ligand thrombopoietin. Nature 369:568, 1994
67. Kaushansky K: Thrombopoietin: The primary regulator of platelet production. Blood 86:419, 1995
68. Kay M, Rothenberg S, Landen CN, et al: In vivo gene therapy of hemophilia B: Sustained partial correction in factor IX-deficient dogs. Science 262:117, 1993
69. Kay M, Landen CN, Rothenberg SR, et al: In vivo hepatic gene therapy: Complete albeit transient correction of factor IX deficiency in hemophilia B dogs. Proc Natl Acad Sei U S A 91:2353, 1994
70. Keith JC Jr, Ferranti TJ, Misra B, et al: Evaluation of recombinant human factor IX: Pharmacokinetic studies in the rat and the dog. Thromb Haemost 73:101, 1994
71. Kiefel V, Santoso S, Weisheit M, et al: Monoclonal antibody-specific immobilization of platelet antigens (MAIPA): A new tool for the identification of platelet-reactive antibodies. Blood 70:1722, 1987
72. Kiefel V, Santoso S, Mueller-Eckhardt C: Serological, biochemical, and molecular aspects of platelet autoantigens. Semin Hematol 29:26, 1992
73. Klein MK, Dow SW, Rosychuk RAW: Pulmonary thromboembolism associated with immune-mediated hemolytic anemia in dogs: Ten cases (1982-1987). J Am Vet Med Assoc 195:246, 1989
74. Kristensen AT, Weiss DJ, Klausner JS, et al: Comparison of microscopic and flow cytometric detection of platelet antibody in dogs suspected of having immunemediated thrombocytopenia. Am J Vet Res 55:1111, 1994
75. Kristensen AT, Weiss DJ, Klausner JS, et al: Detection of antiplatelet antibody with a platelet immunofluorescence assay. J Vet Intern Med 8:36, 1994
76. Kristensen AT, Weiss DJ, Klausner JS: Platelet dysfunction associated with immunemediated thrombocytopenia in dogs. J Vet Intern Med 8:323, 1994
77. Kunicki TJ, Newman PJ: The molecular immunology of human platelet proteins. Blood 80:1386, 1992
78. Lane J, Brown M, Bernstein I, et al: Serological and biochemical analysis of the P1A1 alloantigen of human platelets. Br J Haematol 50:351, 1982
79. Lefkovits J, Plow EF, Topol EJ: Platelet glycoprotein Ilb/IIIa receptors in cardiovascular medicine. N Engl J Med 332:1553, 1995
80. Lewalle JM, Castronovo V, Goffinet G, et al: Malignant cell attachment to endothelium of ex vivo perfused human umbilical vein: Modulation by platelets, plasma and fibronectin. Thromb Res 62:287, 1991
81. Lewis DC, Meyers KM: Effect of anticoagulant and blood storage time on plateletbound antibody concentrations in clinically normal dogs. Am J Vet Res 55:602, 1994
82. Lewis DC, Meyers KM, Callan MB, et al: Detection of platelet-bound and serum platelet-bindable antibodies for diagnosis of idiopathic thrombocytopenic purpura in dogs. J Am Vet Med Assoc 206:47, 1995
83. Lindahl TL, Festin R, Larsson A: Studies of fibrinogen binding to platelets by flow cytometry: An improved method for studies of platelet activation. Thromb Haemost 68:221, 1992
84. Lok S, Kaushansky K, Holly RD, et al: Cloning and expression of murine thrombopoietin cDNA and stimulation of platelet production in vivo. Nature 369:565, 1994
85. Lok S, Foster DC: The structure, biology and potential therapeutic applications of recombinant thrombopoietin. Stem Cells 12:586, 1994
86. Mann KG, Kalafatis M: The coagulation explosion. Cerebrovascular Dis 5:93, 1995
87. Mauser AE, Whitlark J, Whitney KM, et al: A deletion mutation causes hemophilia B in Lhasa Apso dogs. Blood, in press
88. Mauser AE, Whitney KM, Goodman SA, et al: Gene therapy and immune response to adenoviral vectors in normal and hemophilia B dogs. Hum Gene Ther, in press
89. McEver RP, Martin MN: A monoclonal antibody to a membrane glycoprotein binds only to activated platelets. J Biol Chem 259:9799, 1984
90. McMillan R, Tani P, Millard F, et al: Platelet-associated and plasma anti-glycoprotein autoantibodies in chronic ITP. Blood 70:1040, 1987
91. McNeil HP, Simpson RJ, Chesterman CN, et al: Anti-phospholipid antibodies are directed against a complex antigen that includes a lipid-binding inhibitor of coagulation: Beta2-glycoprotein I (apolipoprotein H). Proc Natl Acad Sei U S A 87:4120, 1990
92. Menter DG, Sloane BF, Steinert BW, et al: Platelet enhancement of tumor cell adhesion to subendothelial matrix: Role of platelet cytoskeleton and platelet membrane. J Natl Cancer Inst 79:1077, 1987
93. Menter DC, Steinert BW, Sloane BF, et al: A new in vitro model for investigation of tumor cell-platelet-endothelial cell interactions and concomitant eicosanoid biosynthesis. Cancer Res 47:2425, 1987
94. Methia N, Louache F, Vainchenker W, et al: Oligodeoxynucleotides antisense to the proto-oncogene c-mpl specifically inhibit in vitro megakaryocytopoiesis. Blood 82:1395, 1993
95. Mogi Y, Kogawa K, Takayama T, et al: Platelet aggregation induced by adenosine diphosphate release from cloned murine fibrosarcoma cells is positively correlated with the experimental metastatic potential of the cells. Jpn J Cancer Res 82:192, 1991
96. Mousa SA, Flint S, Lorelli W, et al: Intravenous antiplatelet efficacy and safety of the platelet GPIIb/IIIa antagonist, DMP 728 in anesthetized dogs. Thromb Res 76:109, 1994
97. Nash RA, Burstein SA, Storb R, et al: Thrombocytopenia in dogs induced by granulocyte-macrophage colony-stimulating factor: Increased destruction of circulating platelets. Blood 86:1765, 1995
98. Nesheim ME, Furmaniak-Kazmierczak E, Henin C, et al: On the existence of platelet receptors for factor V(a) and factor VIII(a). Thromb Haemost 70:80, 1993
99. Newman PJ, Derber RS, Aster RH: The human platelet alloantigens, P1A1 and P1A2, are associated with a Ieucine33/proline33 amino acid polymorphism in membrane glycoprotein Ilia and are distinguishable by DNA typing. ] Clin Invest 83:1778, 1989
100. Newman PJ: Platelet GPIIb-IIIa: Molecular variations and alloantigens. Thromb Haemost 66:111, 1991
101. Nichols AJ, Vasko JA, Valocik RE, et al: The in vitro pharmacological profile of SK& F 106760, a novel GPIIb/IIIa antagonist. Thromb Res 75:143, 1994
102. Nierodzik ML, Klepfish A, Karpatkin S: Role of platelets, thrombin, integrin Ilb-IIIa, fibronectin and von Willebrand factor on tumor adhesion in vitro and metastasis in vivo. Thromb Haemost 74:282, 1995
103. Niewiarowski S, McLane MA, Kloczewiak M, et al: Disintegrins and other naturally occurring antagonists of platelet fibrinogen receptors. Semin Hematol 31:289, 1994
104. Nomura S, Yanabu M, Kido H, et al: Significance of cytokines and CD68-posirive microparticles in immune thrombocytopenic purpura. Eur J Haematol 55:49, 1995
105. Northern J, Tvedten HW: Diagnosis of microthrombocytosis and immune-mediated thrombocytopenia in dogs with thrombocytopenia: 68 cases (1987-1989). J Am Vet Med Assoc 200:368, 1992
106. Novotny WF: Tissue factor pathway inhibitor. Semin Thromb Hemost 20:101, 1994
107. Oleksowicz L, Mrowice Z, Schwartz E, et al: Characterization of rumor-induced platelet aggregation: The role of immunorelated GPIb and GPIIb/IIIa expression by MCF-& breast cancer cells. Thromb Res 79:261, 1995
108. Costing JD, Derksen RHWM, Bobbink IWG, et al: Antiphospholipid antibodies directed against a combination of phospholipids with prothrombin, protein C, or protein S: An explanation for their pathogenic mechanism? Blood 81:2618, 1993
109. Pearlstein E, Ambrogio C, Gasic G, et al: Inhibition of the platelet-aggregating activity of two human adenocarcinomas of the colon and an anaplastic murine tumor with a specific thrombin inhibitor: Dansylarginine N-(3-ethyl-l, 5-pentanediyl) amide. Prog Clin Biol Res 89:479, 1982
110. HO. Pegels JG, Bruynes ECE, Engelfriet CP, et al: Pseudothrombocytopenia: An immunologie study on platelet antibodies dependent on ethylene diamine tetra-acetate. Blood 59:157, 1982
111. Pintado CO, Friend M, Lianes D: Characterisation of a membrane receptor on ruminants and equine platelets and peripheral blood leukocytes similar to the human integrin receptor glycoprotein Ilb/IIIa (CD41/61). Vet Immunol Immunopathol 44:359, 1995
112. Plow EF, D'Souza SE, Ginsberg MH: Consequences of the interaction of platelet membrane glycoprotein GPIIb-IIIa (allbp3) and its ligands. J Lab Clin Med 120:198, 1992
113. Plow EF, D'Souza SE, Ginsberg MH: Ligand binding to GPIIb-IIIa: A status report. Semin Thromb Hemost 18:324, 1992
114. Pytela R, Pierschbacher MD, Ginsberg MH, et al: Platelet membrane glycoprotein Ilb/IIIa: A member of a family of Arg-Gly-Asp-specific adhesion receptors. Science 231:1559, 1986
115. Ragan HA: Platelet agglutination induced by ethylenediaminetetraacetic acid in blood samples from a miniature pig. Am J Vet Res 33:2601, 1972
116. Raymond SL, Dodds WJ: Platelet membrane glycoproteins in normal dogs and dogs with hemostatic defects. J Lab Clin Med 93:607, 1979
117. Read MS, Reddick RL, Bode AP, et al: Preservation of hemostatic and structural properties of rehydrated lyophilized platelets: Potential for long-term storage of dried platelets for transfusion. Proc Natl Acad Sei U S A 92:397, 1995
118. Romp KG, Peters WP, Hoff man M: Reticulated platelet counts in patients undergoing autologous bone marrow transplantation: An aid in assessing marrow recovery. Am J Hematol 46:319, 1994
119. Roubey RAS: Autoantibodies to phospholipid-binding plasma proteins: A new view of lupus anticoagulants and other antiphospholipid autoantibodies. Blood 84:2854, 1994
120. Ruggeri ZM: New insights into the mechanisms of platelet adhesion and aggregation. Semin Hematol 31:229, 1994
121. Ruiz-Arguelles A, Vazques-Prado J, Deleze M, et al: Presence of serum antibodies to coagulation protein C in patients with systemic lupus erythematosis is not associated with antigenic or functional protein C deficiencies. Am ] Hematol 44:58, 1993
122. Sakai T, Kiesiel W: Binding of human factors X and Xa to HepG2 and J82 human tumor cell lines. J Biol Chem 265:9105, 1990
123. Sammaritano LR, Gharavi AE, Lockshin MD: Antiphospholipid antibody syndrome: Immunologie and clinical aspects. Semin Arthritis Rheum 20:81, 1990
124. Satoh T, Kouns W, Yamashita Y, et al: Tetrafibricin has a high selectivity for GPIIb/ Ilia: Comparison of the effects of tetrafibricin and RGDS on GPIIb/IIIa and the vitronectin receptor. Biochem Biophys Res Commun 204:325, 1994
125. Scharf RE, Tomer A, Marzec UM, et al: Activation of platelets in blood perfusing angioplasty-damaged coronary arteries: Flow cytometric detection. Arterioscler Thromb 12:1475, 1992
126. Shattil SJ, Hoxie JA, Cunningham M, et al: Changes in the platelet membrane glycoprotein Ilb-IIIa complex during platelet activation. J Biol Chem 260:11107, 1985
127. Shibata Y, Miyaji T, Ichikawa Y, et al: A new platelet antigen system, YukVYukb. Vox Sang 51:334, 1986
128. Shreiner DP, Bell WR: Pseudothrombocytopenia: Manifestation of a new type of platelet agglutinin. Blood 42:541, 1973
129. Shulman NR, Marder VJ, Hiller MC, et al: Platelet and leukocyte isoantigens and their antibodies: Serologie, physiologic and clinical studies. Progress in Hematology 4:222, 1964
130. Silverstein RL, Febbraio M: Identification of lysosome-associated membrane protein2 as an activation-dependent platelet surface glycoprotein. Blood 80:1470, 1992
131. Soute BAM, Ulrich MMW, Watson ADJ, et al: Congenital deficiency of all vitamin Kdependent blood coagulation factors due to a defective vitamin K-dependent carboxylase in Devon Rex cats. Thromb Haemost 68:521, 1992
132. Souyri M, Vigon I, Penciolelli JF, et al: A putative truncated cytokine receptor gene transduced by the myeloproliferative leukemia virus immortalizes hematopoietic progenitors. Cell 63:1137, 1990
133. Sprugel KH, Humes JM, Grossman A, et al: Recombinant thrombopoietin stimulates rapid platelet recovery in thrombocytopenic mice [abstractJ. Blood 84:242a, 1994
134. Stolman GJ: Plasma thromboxane A2 and prostacyclin concentrations in squamous cell carcinoma of the head and neck. J Surg Oncol 38:33, 1988
135. Stone MS, Johnstone IB, Brooks M, et al: Lupus-type anticoagulant in a dog with hemolysis and thrombosis. J Vet Intern Med 8:57, 1994
136. Sullivan PS, Manning KL, McDonald TP: Association of mean platelet volume and bone marrow megakaryocytopoiesis in thrombocytopenic dogs: 60 cases (1984-1993). J Am Vet Med Assoc 206:332, 1995
137. Tang DC, Onoda JM, Steinert BW, et al: Phenotypic properties of cultured tumor cells: Integrin allbβ3 expression, tumor cell-induced platelet aggregation, and tumorcell adhesion to endothelium as important parameters of experimental metastasis. Int J Cancer 54:338, 1993
138. Tinlin S, Webster S, Giles AR: The development of homologous (canine/anti-canine) antibodies in dogs with haemophilia A (factor VIII deficiency): A ten-year longitudinal study. Thromb Haemost 69:21, 1993
139. Tligui N, Ruth GR: Ferula cotnmunis variety brevifolia intoxication of sheep. Am J Vet Res 55:1558, 1994
140. Tligui N, Ruth GR, Felice LJ: Plasma ferulenol concentration and activity of clotting factors in sheep with Ferula communis variety brevifolia intoxication. Am J Vet Res 55:1564, 1994
141. Triplett DA: Coagulation assays for the lupus anticoagulant: Review and critique of current methodology. Stroke 23(suppl. I):ll, 1992
142. Triplett DA: Antiphospholipid-protein antibodies: Laboratory detection and clinical relevance. Thromb Res 78:1, 1995
143. Tsuruo T, Watanabe M, Oh-hara T: Stimulation of the growth of metastatic clones of mouse colon adenocarcinoma 26 in vitro by platelet-derived growth factor. Jpn J Cancer Res 80:136, 1989
144. Tuddenham EGD, Schwaab R, Seehafer J, et al: Haemophilia A: Database of nucleotide substitutions, deletions, insertions and rearrangements of the factor VIII gene, second edition. Nucleic Acids Res 22:4851, 1994
145. Valentine LA, Ladisch S: Circulating tumor gangliosides enhance platelet activation. Blood 83:2872, 1994
146. Veenhoven WA, van der Schans GS, Huiges W, et al: Pseudothrombocytopenia due to agglutinins. Am J Clin Pathol 72:1005, 1979
147. Vergote IB, vanDam PA, Laekeman GM, et al: Prostacyclin/thromboxane ratio in human breast cancer. Tumour Biol 12:261, 1991
148. Vicari A, Banfi G, Bonini PA: EDTA-dependent pseudothrombocytopenia: A 12month epidemiological study. Scand ] Clin Lab Invest 48:537, 1988
149. von dem Borne AEGK, von Riesz E, Verbeugt FWA, et al: Baka, a new platelet-specific antigen involved in neonatal allo-immune thrombocytopenia. Vox Sang 39:113, 1980
150. Wagenvoord RJ, Hendrix HH, Kai H, et al: A chromogenic test to determine the procoagulant phospholipids in platelet-rich plasma and whole blood. Thromb Haemost 72:582, 1994
151. Walkowiak B, Michalak E, Borkowska E, et al: Concentration of RGDS-containing degradation products in urémie plasma is correlated with progression in renal failure. Thromb Res 76:133, 1994
152. Watanabe K, Takeuchi K, Kawai Y, et al: Automated measurement of reticulated platelets in estimating thrombopoiesis. Eur J Haematol 54:163, 1995
153. Weiss HJ: Scott Syndrome: A disorder of platelet coagulant activity. Semin Hematol 31:312, 1994
154. Welles EG, Bourne C, Tyler JW, et al: Detection of activated feline platelets in plateletrich plasma by use of fluorescein-labeled antibodies and flow cytometry. Vet Pathol 31:553, 1994
155. Wendling F, Maraskovsky E, Debili N, et al: c-Mpl ligand is a humoral regulator of megakaryocytopoiesis. Nature 369:571, 1994
156. Williamson P, Bevers EM, Smeets EF, et al: Continuous analysis of the mechanisms of activated transbilayer lipid movement in platelets. Biochemistry 34:10448, 1995
157. Yanabu M, Nomura S, Fukuroi T, et al: Synergistic action in platelet activation induced by an antiplatelet autoantibody in ITP. Br J Haematol 78:87, 1991
158. Zamarron C, Ginsberg MH, Plow EF: Monoclonal antibodies specific for a conformationally altered state of fibrinogen. Thromb Haemost 64:41, 1990
159. Zamarron C, Ginsberg MH, Plow EF: A receptor induced-binding site in fibrinogen elicited by its interaction with platelet membrane glycoprotein Ilb-IIIa. J Biol Chem 266:16193, 1991
160. Zimrin AB, Gidwitz S, Lord S, et al: The genomic organization of platelet glycoprotein Ilia. J Biol Chem 265:8590, 1990
161. Zwaal RFA, Comfurius P, Bevers EM: Platelet procoagulant activity and microvesicle formation: Its putative role in hemostasis and thrombosis. Biochim Biophys Acta 1180:1, 1992