Endotoxin-induced alterations in insulin-stimulated phosphorylation of insulin receptor, IRS-1, and map kinase in skeletal muscle

Shock

Volumn 6, Issue 3, 1996, Pages 164-170

  Fan, Jie ^a   Li, Yue Hua ^a   Wojnar, Margaret M ^a   Lang, Charles H ^a  

^a STONY BROOK UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; CREATINE PHOSPHATE; ENDOTOXIN; GLUCOSE; GLYCOGEN; INSULIN; INSULIN RECEPTOR SUBSTRATE 1 PROTEIN; INSULIN RECEPTOR SUBSTRATE-1 PROTEIN; LIPOPOLYSACCHARIDE; PHOSPHOPROTEIN; PROTEIN KINASE (CALCIUM,CALMODULIN);

ANIMAL; ARTICLE; BIOSYNTHESIS; CHEMICALLY INDUCED DISORDER; DRUG EFFECT; GLUCOSE BLOOD LEVEL; HYPERGLYCEMIA; MALE; METABOLISM; PHOSPHORYLATION; RAT; SIGNAL TRANSDUCTION; SKELETAL MUSCLE; SPRAGUE DAWLEY RAT;

ADENOSINE TRIPHOSPHATE; ANIMALS; BLOOD GLUCOSE; CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE; ENDOTOXINS; GLUCOSE; GLYCOGEN; HYPERGLYCEMIA; INSULIN; LIPOPOLYSACCHARIDES; MALE; MUSCLE, SKELETAL; PHOSPHOCREATINE; PHOSPHOPROTEINS; PHOSPHORYLATION; RATS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION;

EID: 0030228351     PISSN: 10732322     EISSN: None     Source Type: Journal    
DOI: 10.1097/00024382-199609000-00002     Document Type: Article

References (40)

1. Lang CH: Sepsis-induced insulin resistance in rats is mediated by a β-adrenergic mechanism. Am J Physiol 262:E703-E711, 1992.
2. Virkamaki A, Yki-Jarvinen H: Mechanisms of insulin resistance during acute endotoxemia. Endocrinology 134:2072-2078, 1994.
3. Lang CH, Dobrescu C, Meszaros K: Insulin-mediated glucose utilization of individual tissues during sepsis. Metabolism 39:1096-1107, 1990.
4. Kahn CR: Insulin resistance, insulin insensitivity, and insulin unresponsiveness: A necessary distinction. Metabolism 27:1893-1902, 1978.
5. Cheatham B, Kahn CR: Insulin action and the insulin signaling network. Endocrine Rev 16:117-142, 1995.
6. Edina Y, Araki E, Taira M, et al: Replacement of tyrosine residue 1030 in the putative ATP-binding region of the insulin receptor abolishes insulin-and antibody-stimulated glucose uptake and receptor kinase activity. Proc Natl Acad Sci USA 84:704-708, 1987.
7. Giorgino F, Chen J-H, Smith RJ: Changes in tyrosine phosphorylation of insulin receptors and a 170,000 molecular weight nonreceptor protein in vivo in skeletal muscle of streptozotocin-induced diabetic rats: Effects of insulin and glucose. Endocrinology 130:1433-1444, 1992.
8. Saad MJ, Araki E, Miralpeix, M, Rothenberg PL, White MF, Kahn CR: Regulation of insulin receptor substrate-1 in liver and muscle of animal models of insulin resistance. J Clin Invest 90:1839-1849, 1992.
9. Giorgino F, Almahfouz A, Goodyear LJ, Smith RJ: Glucocorticoid regulation of insulin receptor and substrate IRS-1 tyrosine phosphorylation in rat skeletal muscle in vivo. J Clin Invest 91:2020-2030, 1993.
10. Goodyear LJ, Giorgino F, Sherman LA, Carey J, Smith RJ, Dohm GL: Insulin receptor phosphorylation, insulin receptor substrate-1 phosphorylation, and phosphatidylinositol 3-kinase activity are decreased in intact skeletal muscle strips from obese subjects. J Clin Invest 95:2195-2204, 1995.
11. Denton RM, Tavare JM: Does mitogen-activated-protein kinase have a role in insulin action? The cases for and against. Eur J Biochem 227:597-611, 1995.
12. Fan J, Molina PE, Gelato MC, Lang CH: Differential tissue regulation of insulin-like growth factor-I content and binding proteins after endotoxin. Endocrinology 134:1685-1692, 1994.
13. Lang CH: IGF-I stimulates muscle glucose uptake during sepsis. Shock 5:22-27, 1996.
14. Finegood DT, Bergman RN, Vranic M: Estimation of endogenous glucose production during hyperinsulinemia-euglycemic glucose clamps. Diabetes 36:914-924, 1987.
15. Butler P, Bell P, Rizza R: Choice and use of tracers. Horn Metab Res 24(Suppl):20-25, 1990.
16. Rossetti L, Giaccari A: Relative contribution of glycogen synthesis and glycolysis to insulin-mediated glucose uptake: A dose-response euglycemic clamp study in normal and diabetic rats. J Clin Invest 85:1785-1792, 1990.
17. Keepler D, Decker K: Glycogen determination with amyloglucosidase. In Bergmeyer HU (ed): Methods of Enzymatic Analysis. New York: Academic Press, 1974, pp 1127-1131.
18. Burant CR, Treutelaar MK, Buse MG: Diabetes-induced functional and structural changes in insulin receptors from rat skeletal muscle. J Clin Invest 77:260-270, 1986.
19. Scatchard G: The attractions of proteins for small molecules and ions. Ann NY Acad Sci 51:660-672, 1949.
20. Munson PJ, Rodbard D: Ligand: A versatile computerized approach for characterization of ligand-binding systems. Anal Biochem 107:220-239, 1980.
21. Harlow DL, Land D: Antibodies: A Laboratory Manual. Cold Spring Harbor: NY, 1988, pp 421-470.
22. McDonough KH, Henry JJ, Lang CH, Spitzer JJ: Substrate utilization and high energy phosphate levels of hearts from hyperdynamic septic rats. Circ Shock 18:161-170, 1986.
23. Lang CH, Dobrescu C, Bagby GJ: Tumor necrosis factor impairs insulin action on peripheral glucose disposal and hepatic glucose output. Endocrinology 130:43-52, 1992.
24. Black BR, Brooks DC, Bessey PA, Wolfe RR, Wilmore DW: Mechanisms of insulin resistance following injury. Ann Surg 196:420-435, 1982.
25. Lang CH, Skrepnik N, Dobrescu C, Burns AH: Impairment of insulin action on peripheral glucose and hepatic glucose production in tumor-bearing rats. Am J Physiol 265:R356-R364, 1993.
26. Drobney EC, Abramson EC, Baumann G: Insulin receptors in acute infection: A study of factors conferring insulin resistance. J Clin Endocrinol Metab 58:710-716, 1984.
27. Frayn KN, Le Marchand-Brustel Y, Freychet P: Studies on the mechanism of insulin resistance after injury in the mouse. Diabetologia 14:337-341, 1978.
28. Abernathy CO, Bhathena SJ, Recant L, Zimmerman HJ, Utili R: Effects of acute and chronic endotoxin treatment on glucagon and insulin receptors on rat liver plasma membranes. Horm Metab Res 14:468-471, 1982.
29. Morenkova SA: Mechanism of hyperglycemia induced by extensive wounds and generalized surgical infection. Acta Diabetol Lat 24:119-132, 1987.
30. Holley DC, Spitzer JA: Insulin action and binding in adipocytes exposed to endotoxin in vitro and in vivo. Circ Shock 7:3-12, 1980.
31. Vary TC, Drnevich D, Jurasinski C, Brennan WA: Mechanisms regulating skeletal muscle glucose metabolism in sepsis. Shock 3:403-410, 1995.
32. Kruszynska YT, Halban PA, Kahn CR, Whiate MF: Activation of liver and muscle insulin receptor tyrosine kinase activity during in vivo insulin administration in rats. Diabetologia 33:77-83, 1990.
33. Zeller WP, The SM, Sweet M, et al: Altered glucose transporter mRNA abundance in a rat model of endotoxic shock. Biochem Biophys Res Commun 176:535-540, 1991.
34. Araki E, Lipes MA, Patti M, et al: Alternative pathway of insulin signalling in mice with targeted disruption of the IRS-1 gene. Nature 372:186-190, 1994.
35. Zhou GX, Meier KE, Buse MG: Sequential activation of two mitogen-activated protein (MAP) kinase isoforms in rat skeletal muscle following insulin injection. Biochem Biophys Res Commun 197:578-584, 1993.
36. Marshall CJ: MAP kinase kinase kinase, MAP kinase kinase and MAP kinase. Curr Opin Genet Dev 4:82-89, 1994.
37. Fong Y, Lowry SF: Tumor necrosis factor in the pathophysiology of infection and sepsis. Clin Immunol Immunopathol 55:157-170, 1990.
38. Petit F, Bagby GJ, Lang CH: Tumor necrosis factor mediates zymosan-induced increase in glucose flux and insulin resistance. Am J Physiol 268:E219-E228, 1995.
39. Hotamisligil GS, Spiegelman BM: Tumor necrosis factor α: A key component of the obesity-diabetes link. Diabetes 43:1271-1278, 1994.
40. Kanety H, Feinstein R, Papa MZ, Hemi R, Karasik A: Tumor necrosis factor α-induced phosphorylation of insulin receptor substrate-1 (IRS-1): Possible mechanism for suppression of insulin-stimulated tyrosine phosphorylation of IRS-1. J Biol Chem 270:23780-23784, 1995.