Kinetics of Cu2+ inhibition of Na+/K+-ATPase

Toxicology Letters

Volumn 87, Issue 1, 1996, Pages 31-38

  Li, Jie ^a   Lock, Robert A C ^a   Klaren, Peter H M ^a   Swarts, Herman G P ^b   Schuurmans Stekhoven, Feico M A H ^b   Wendelaar Bonga, Sjoerd E ^a   Flik, Gert ^a  

^a Faculty of Science   (Netherlands)

^b RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Copper; K+ pNPPase; Kinetics; Na+ K+ ATPase (EC 3.6.1.3)

Indexed keywords

4 NITROPHENYLPHOSPHATASE; ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); COPPER; COPPER ION; DITHIOTHREITOL; MAGNESIUM;

ANIMAL TISSUE; ARTICLE; DEPHOSPHORYLATION; ENZYME ACTIVITY; ENZYME KINETICS; KIDNEY; NONHUMAN; PRIORITY JOURNAL; RABBIT; ANIMAL; DRUG ANTAGONISM; ENZYME SPECIFICITY; ENZYMOLOGY; IN VITRO STUDY; METABOLISM;

ANIMALIA; ORYCTOLAGUS CUNICULUS;

4-NITROPHENYLPHOSPHATASE; ANIMALS; COPPER; DITHIOTHREITOL; KIDNEY; MAGNESIUM; NA(+)-K(+)-EXCHANGING ATPASE; RABBITS; SUBSTRATE SPECIFICITY;

EID: 0030222923     PISSN: 03784274     EISSN: None     Source Type: Journal    
DOI: 10.1016/0378-4274(96)03696-X     Document Type: Article

References (30)

1. + across cell membranes. Phys. Rev. 45, 596-617.
2. [2] Skou, J.C. (1971) Sequence of steps in the Na-K activated enzyme system in relation to sodium and potassium transport. Curr. Top. Bioenerg. 4, 357-389.
3. [3] Schuurmans Stekhoven, F.M.A.H. and Bonting, S.L. (1981) Sodium-potassium-activated adenosinetriphosphatase. Membrane transport. In: S.L. Bonting and J.J.H.H.M. de Pont (Eds.), Elsevier and North-Holland Biomedical Press, Amsterdam.
4. [4] Rossier, B., Greering, K. and Kraehenbuhl, J.P. (1987) Regulation of sodium pump: how and why? Trends Biol. Sci. 12, 483-487.
5. [5] Lamb, J.F. (1990) Regulation of abundance of sodium pumps in isolated animal cells. Int. J. Biochem. 22, 1365-1370.
6. +-ATPase. Biochim. Biophys. Acta 1154, 201-222.
7. +-ATPase XLII. Evidence for two classes of essential sulfhydryl groups. Biochim. Biophys. Acta 522, 602-613.
8. [8] Underwood, E.J. (1977) Copper. In: Trace Elements in Human and Animal Nutrition, Academic Press, New York, pp. 56-108.
9. [9] Bowler, K. and Duncan, C.J. (1970) The effect of copper on membrane enzymes. Biochim. Biophys. Acta 196, 116-119.
10. +-ATPase with copper. Biochim. Biophys. Acta 129, 229-236.
11. +-ATPase by trace metals: relation to renal and cardiovascular damage. Nephron, 44, 329-336.
12. [12] Lauren, D.J. and McDonald, D.G. (1987) Acclimation to copper by rainbow trout, Salmo gairdnerii. Biochem. Can. J. Fish Aquat. Sci., 44, 105-111.
13. 2+-exchanger. Pflüger Arch. 428, 461-467.
14. [14] Salhany, J., Swanson, J.C., Cordes, K.A., Ganies, S.B. and Gaines, K.C. (1978) Evidence suggesting direct oxidation of human erythrocyte membrane sulfhydryls by copper. Biochem. Biophys. Res. Commun. 82, 1294-1299.
15. [15] Butkus, D.E. and Jones, F.T. (1982) Reversal of copper-induced inhibition of vasopressin responsiveness by reducing agents. Biochim. Biophys. Acta 685, 203-206.
16. 2+ effect on rat liver mitochondria. J. Inorg. Biochem. 21, 241-251.
17. 2+ transport in renal proximal tubule. J. Membrane Biol. 113, 1-12.
18. +-ATPase and ouabain binding by mercuric chloride. Toxicol. Lett. 51, 109-116.
19. +-para-nitrophenyl phosphatase activity and protection by thiol reagents. Biochem. Int. 20, 1011-1018.
20. [20] Stacey N.H. (1986) Protective effects of dithiothreitol on cadmium-induced injury in isolated rat hepatocytes. Toxicol. Appl. Pharmacol. 82, 224-232.
21. [21] Sillén, L. and Martèll, A.E. (1964) Stability Constants of Metal-ion Complexes. The Chemical Society, London, Special Publication No. 17.
22. +-ATPase: ligand-induced conformational transitions and alterations in subunit interactions evidenced by cross-linking studies. Biochemistry 19, 1132-1140.
23. [23] Schoenmakers, Th.J.M., Visser, G., Flik, G. and Theuvenet, A.P.R. (1992) Chelator: an improved method for computing metal ion concentrations in physiological solutions. Biotechniques 12, 870-879.
24. +-ATPase. III Purification from the outer medulla of mamalian kidney after selective removal of membrane components by sodium dodecylsulfate. Biochim. Biophys. Acta 356, 815-817.
25. +-ATPase. XLI. Effects of N-ethylmaleimide on overall and partial reactions. Biochim. Biophys. Acta 483, 181-192.
26. [26] Bonting, S.L., Simon, K.A. and Hawkins, N.M. (1961) Studies on Na-K-ATPase I. Quantitive distribution in several tissues of the cat. Arch. Biochem. Biophys. 95, 416-423.
27. [27] Peters, R., Shorthouse, M. and Walshe, J.M. (1966) Studies on the toxicity of copper. II. The behaviour of microsomal membrane ATPase of pigeon's brain tissue to copper and some other metallic substances. Proc. R. Soc. B166, 285.
28. 2+ pump: a molecular interpretation. J. Biol. Chem. 264, 5613-5615.
29. [29] Verbost, P.M., Flik, G., Lock, R.A.C. and Wendelaar Bonga, S.E. (1988) Cadmium inhibits plasma membrane calcium transport. J. Membrane Biol. 102, 97-104.
30. [30] Ahammaladsahib, K.I., Jinna, R.R. and Desaiah, D. (1989) Protection against cadmium toxicity and enzyme inhibition by dithiothreitol. Cell Biochem. Funct. 7, 185-192.