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1
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0021633364
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Macromolecule-drug conjugates in targeted cancer chemotherapy
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[1] H. Sezaki and M. Hashida, Macromolecule-drug conjugates in targeted cancer chemotherapy, CRC Crit. Rev. Ther. Drug Carrier Syst. 1 (1984) 1-38.
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(1984)
CRC Crit. Rev. Ther. Drug Carrier Syst.
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, pp. 1-38
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Sezaki, H.1
Hashida, M.2
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2
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0027982550
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Pharmacokinetics in design of polymeric drug delivery systems
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[2] M. Hashida and Y. Takakura, Pharmacokinetics in design of polymeric drug delivery systems, J. Control. Release 31 (1994) 163-171.
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(1994)
J. Control. Release
, vol.31
, pp. 163-171
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Hashida, M.1
Takakura, Y.2
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3
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0012020389
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Control of disposition characteristics of proteins by chemical modification with carbohydrates
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B.-K. Kim, E.B. Lee, C.-K. Kim and Y.N. Han (Eds.), The Pharmaceutical Society of Korea, Seoul
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[3] M. Hashida, Y. Takakura and H. Sezaki, Control of disposition characteristics of proteins by chemical modification with carbohydrates, in: B.-K. Kim, E.B. Lee, C.-K. Kim and Y.N. Han (Eds.), Advances in New Drug Development, The Pharmaceutical Society of Korea, Seoul, 1991, pp. 741-749.
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(1991)
Advances in New Drug Development
, pp. 741-749
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Hashida, M.1
Takakura, Y.2
Sezaki, H.3
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4
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0025148495
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Disposition characteristics of macromolecules in tumor-bearing mice
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[4] Y. Takakura, T. Fujita, M. Hashida and H. Sezaki, Disposition characteristics of macromolecules in tumor-bearing mice, Pharm. Res. 7 (1990) 339-346.
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(1990)
Pharm. Res.
, vol.7
, pp. 339-346
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Takakura, Y.1
Fujita, T.2
Hashida, M.3
Sezaki, H.4
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5
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0025777450
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Hepatic disposition characteristics of electrically charged macromolecules in rat in vivo and in the perfused liver
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[5] K. Nishida, K. Mihara, T. Takino, S. Nakane, Y. Takakura, N. Hashida and H. Sezaki, Hepatic disposition characteristics of electrically charged macromolecules in rat in vivo and in the perfused liver, Pharm. Res. 8 (1991) 437-444.
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(1991)
Pharm. Res.
, vol.8
, pp. 437-444
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Nishida, K.1
Mihara, K.2
Takino, T.3
Nakane, S.4
Takakura, Y.5
Hashida, N.6
Sezaki, H.7
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6
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0028351444
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Pharmacokinetics of succinylated proteins and dextran sulfate in mice: Implications for hepatic targeting of protein drugs by direct succinylation via scavenger receptors
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[6] Y. Takakura, T. Fujita, H. Furitsu, M. Nishikawa, H. Sezaki and M. Hashida, Pharmacokinetics of succinylated proteins and dextran sulfate in mice: implications for hepatic targeting of protein drugs by direct succinylation via scavenger receptors, Int. J. Pharm. 105 (1994) 19-29.
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(1994)
Int. J. Pharm.
, vol.105
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Takakura, Y.1
Fujita, T.2
Furitsu, H.3
Nishikawa, M.4
Sezaki, H.5
Hashida, M.6
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7
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0026795029
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Disposition characteristics of macromolecules in the perfused tissue-isolated tumor preparation
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[7] H. Imoto, Y. Sakamura, K. Ohkouchi, R. Atsumi, Y. Takakura, H. Sezaki and M. Hashida, Disposition characteristics of macromolecules in the perfused tissue-isolated tumor preparation, Cancer Res. 52 (1992) 4396-4401.
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(1992)
Cancer Res.
, vol.52
, pp. 4396-4401
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Imoto, H.1
Sakamura, Y.2
Ohkouchi, K.3
Atsumi, R.4
Takakura, Y.5
Sezaki, H.6
Hashida, M.7
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8
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0017201417
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2-Imino-2-methoxyethyl 1-thioglycoside: New reagents for attaching sugars to proteins
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[8] Y. Lee, C. Stowell and M. Krantz, 2-Imino-2-methoxyethyl 1-thioglycoside: new reagents for attaching sugars to proteins, Biochemistry 15 (1976) 3956-3963.
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(1976)
Biochemistry
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Lee, Y.1
Stowell, C.2
Krantz, M.3
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9
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0028210543
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Targeting delivery of protein drugs by chemical modification
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[9] M. Hashida, M. Nishikawa, F. Yamashita and Y. Takakura, Targeting delivery of protein drugs by chemical modification, Drug Dev. Ind. Pharm. 20 (1994) 581-590.
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(1994)
Drug Dev. Ind. Pharm.
, vol.20
, pp. 581-590
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Hashida, M.1
Nishikawa, M.2
Yamashita, F.3
Takakura, Y.4
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10
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0029049810
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The fate of plasmid DNA after intravenous injection in mice: Involvement of scavenger receptors in its hepatic uptake
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[10] K. Kawabata Y. Takakura and M. Hashida, The fate of plasmid DNA after intravenous injection in mice: involvement of scavenger receptors in its hepatic uptake, Pharm. Res., 12 (1995) 825-830.
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(1995)
Pharm. Res.
, vol.12
, pp. 825-830
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Kawabata, K.1
Takakura, Y.2
Hashida, M.3
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11
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0029160070
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Stability and pharmacokinetic characteristics of oligonucleotides modified at terminal linkages in mice
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[11] T. Miyao, Y. Takakura, T. Akiyama, F. Yoneda, H. Sezaki and M. Hashida, Stability and pharmacokinetic characteristics of oligonucleotides modified at terminal linkages in mice, Antisense Res. Dev. 5 (1995) 115-121.
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(1995)
Antisense Res. Dev.
, vol.5
, pp. 115-121
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Miyao, T.1
Takakura, Y.2
Akiyama, T.3
Yoneda, F.4
Sezaki, H.5
Hashida, M.6
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13
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0002079949
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Disposition and tumor localization of mitomycin C-dextran conjugates in mice
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[13] Y. Takakura, A. Takagi, M. Hashida and H. Sezaki, Disposition and tumor localization of mitomycin C-dextran conjugates in mice, Pharm. Res. 4 (1987) 293-300.
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(1987)
Pharm. Res.
, vol.4
, pp. 293-300
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Takakura, Y.1
Takagi, A.2
Hashida, M.3
Sezaki, H.4
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14
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0026663226
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Pharmacokinetics of receptor-mediated hepatic uptake of glycosylated albumin in mice
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[14] M. Nishikawa, Y. Ohtsubo, J. Ohno, T. Fujita, Y. Koyama, F. Yamashita, M. Hashida and H. Sezaki, Pharmacokinetics of receptor-mediated hepatic uptake of glycosylated albumin in mice, Int. J. Pharm. 85 (1993) 75-85.
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(1993)
Int. J. Pharm.
, vol.85
, pp. 75-85
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Nishikawa, M.1
Ohtsubo, Y.2
Ohno, J.3
Fujita, T.4
Koyama, Y.5
Yamashita, F.6
Hashida, M.7
Sezaki, H.8
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15
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0028418574
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Soluble polymers for lectin-mediated drug targeting
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[15] L.W. Seymour, Soluble polymers for lectin-mediated drug targeting, Adv. Drug Delivery Rev. 14 (1994) 89-111.
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(1994)
Adv. Drug Delivery Rev.
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Seymour, L.W.1
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16
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0027102397
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Therapeutic effect of superoxide dismutase derivatives modified with mono-or polysaccharides on hepatic injury induced by ischemia/reperfusion
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[16] T. Fujita, H. Furitsu, M. Nishikawa, Y. Takakura, H. Sezaki and M. Hashida, Therapeutic effect of superoxide dismutase derivatives modified with mono-or polysaccharides on hepatic injury induced by ischemia/reperfusion, Biochem. Biophys. Res. Commun. 189 (1992) 191-196.
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(1992)
Biochem. Biophys. Res. Commun.
, vol.189
, pp. 191-196
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Fujita, T.1
Furitsu, H.2
Nishikawa, M.3
Takakura, Y.4
Sezaki, H.5
Hashida, M.6
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17
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0028035475
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Improvement of therapeutic effect of human recombinant superoxide dismutase on ischemic acute renal failure in the rat via cationization and conjugation with polyethylene glycol
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[17] K. Mihara, Y. Oka, K. Sawai, Y. Takakura and M. Hashida, Improvement of therapeutic effect of human recombinant superoxide dismutase on ischemic acute renal failure in the rat via cationization and conjugation with polyethylene glycol, J. Drug Targeting 2 (1994) 317-321.
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(1994)
J. Drug Targeting
, vol.2
, pp. 317-321
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Mihara, K.1
Oka, Y.2
Sawai, K.3
Takakura, Y.4
Hashida, M.5
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18
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0028297535
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Targeted delivery of superoxide dismutase to macrophages via mannose-receptor-mediated mechanism
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[18] Y. Takakura, S. Masuda, H. Tokuda, M. Nishikawa and M. Hashida, Targeted delivery of superoxide dismutase to macrophages via mannose-receptor-mediated mechanism, Biochem. Pharmacol. 47 (1994) 853-858.
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(1994)
Biochem. Pharmacol.
, vol.47
, pp. 853-858
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Takakura, Y.1
Masuda, S.2
Tokuda, H.3
Nishikawa, M.4
Hashida, M.5
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19
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0028258088
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Control of the disposition profiles of proteins in the kidney via chemical modification
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[19] Y. Takakura, K. Mihara and M. Hashida, Control of the disposition profiles of proteins in the kidney via chemical modification, J. Control. Release 28 (1994) 111-119.
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(1994)
J. Control. Release
, vol.28
, pp. 111-119
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Takakura, Y.1
Mihara, K.2
Hashida, M.3
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20
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0028863071
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Physicochemical and pharmacokinetic characteristics of plasmid DNA complexed with cationic liposomes
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[20] R.I. Mahato, K. Kawabata, T. Nomura, Y. Takakura and M. Hashida, Physicochemical and pharmacokinetic characteristics of plasmid DNA complexed with cationic liposomes, J. Pharm. Sci. 84 (1995) 1267-1271.
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(1995)
J. Pharm. Sci.
, vol.84
, pp. 1267-1271
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Mahato, R.I.1
Kawabata, K.2
Nomura, T.3
Takakura, Y.4
Hashida, M.5
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21
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0027296533
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Stability and in vivo disposition characteristics of oligonucleotides and oligonucleotides conjugate with macromolecules
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[21] T. Miyao, Y. Takakura and M. Hashida, Stability and in vivo disposition characteristics of oligonucleotides and oligonucleotides conjugate with macromolecules, Proc. Intl. Symp. Control. Rel. Bioact. Mater. 20 (1993) 492-493.
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(1993)
Proc. Intl. Symp. Control. Rel. Bioact. Mater.
, vol.20
, pp. 492-493
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Miyao, T.1
Takakura, Y.2
Hashida, M.3
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