Establishment of an in vitro assay system for screening hepatitis C virus protease inhibitors using high performance liquid chromatography

Antiviral Research

Volumn 32, Issue 1, 1996, Pages 9-18

  Sudo, Kenji ^a,c   Inoue, Hiroshi ^a   Shimizu, Yasuaki ^b   Yamaji, Kayo ^b   Konno, Kenji ^a   Shigeta, Shiro ^c   Kaneko, Takashi ^d   Yokota, Tomoyuki ^a   Shimotohno, Kunitada ^d  

^a Rational Drug Design Laboratories   (Japan)

^b ASTELLAS PHARMA INC   (Japan)

^c FUKUSHIMA MEDICAL UNIVERSITY   (Japan)

^d NATIONAL CANCER CENTER RESEARCH INSTITUTE   (Japan)

Author keywords

Hepatitis C virus; High performance liquid chromatography; NS3 NS4A fusion protein; Protease inhibitors; Synthetic peptide substrate

Indexed keywords

ANTIVIRUS AGENT; CHYMOSTATIN; DYFLOS; HYBRID PROTEIN; PROTEINASE; PROTEINASE INHIBITOR; SYNTHETIC PEPTIDE; TOSYLLYSYL CHLOROMETHYL KETONE; VIRUS ENZYME;

ANTIVIRAL ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG RESEARCH; ENZYME ACTIVITY; EXPRESSION VECTOR; HEPATITIS C; HEPATITIS C VIRUS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IN VITRO STUDY; MOLECULAR CLONING; NONHUMAN; PRIORITY JOURNAL; SCREENING;

HEPATITIS C VIRUS;

EID: 0030222125     PISSN: 01663542     EISSN: None     Source Type: Journal    
DOI: 10.1016/0166-3542(95)00969-8     Document Type: Article

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