Iron depletion and virulence in Staphylococcus aureus

FEMS Microbiology Letters

Volumn 141, Issue 2-3, 1996, Pages 117-127

  Trivier, D ^a   Courcol, R J ^a  

^a LILLE UNIVERSITY HOSPITAL   (France)

Author keywords

Iron; Staphylococcus aureus; Virulence

Indexed keywords

2 OXOGLUTARIC ACID; 2,3 DIAMINOPROPIONIC ACID; ADHESIN; AEROBACTIN; AMIKACIN; BETA LACTAM ANTIBIOTIC; CATECHOL; CHELATING AGENT; CITRIC ACID; COAGULASE; DEFEROXAMINE; ENTEROCHELIN; ENZYME; ETHYLENEDIAMINE; FERRIC ION; GLYCOPROTEIN; HEMOLYSIN; HYDROXAMIC ACID; IRON; IRON BINDING PROTEIN; LACTOFERRIN; METALLOPROTEIN; ORNITHINE; OXACILLIN; RECEPTOR; RESIN; SIDEROPHORE; TRANSFERRIN; TRANSFERRIN RECEPTOR; UNINDEXED DRUG;

BACTERIAL GROWTH; BACTERIAL INFECTION; BACTERIAL VIRULENCE; BINDING SITE; CULTURE MEDIUM; DRUG DESIGN; GENE; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PH; PHAGOCYTOSIS; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; REVIEW; SIGNAL TRANSDUCTION; STAPHYLOCOCCUS AUREUS;

BACTERIA (MICROORGANISMS); STAPHYLOCOCCUS AUREUS; STAPHYLOCOCCUS EPIDERMIDIS;

EID: 0030222101     PISSN: 03781097     EISSN: None     Source Type: Journal    
DOI: 10.1016/0378-1097(96)00233-9     Document Type: Short Survey

References (51)

1. [1] Wooldridge, K.G. and Williams, P.H. (1993) Iron uptake mechanisms of pathogenic bacteria. FEMS Microbiol. Rev. 12, 325-348.
2. [2] Weinberg, E.D. (1978) Iron and infection. Microbiol. Rev. 42, 45-66.
3. [3] Letendre, E.D. and Holbein, B.E. (1984) Mechanisms of impaired iron release by the reticuloendothelial system during the hypoferremic phase of experimental Neisseria meningitidis infection in mice. Infect. Immun. 44, 320-325.
4. [4] Neilands, J.B. (1981) Microbial iron compounds. Annu. Rev. Biochem. 50, 715-731.
5. [5] Griffiths, E., Chart, H. and Stevenson P. (1988) High-affinity iron uptake systems and bacterial virulence. In: Virulence Mechanisms of Bacterial Pathogens (Roth, J.A., Ed.), pp. 121-137. American Society for Microbiology, Washington, D.C.
6. [6] Neilands, J.B. (1982) Microbial envelope proteins related to iron. Annu. Rev. Microbiol. 36, 285-309.
7. [7] Arnow, E.L. (1937) Colorimetric determination of the compounds of 3,4-dihydroxyphenyl-alanine-tyrosine mixtures. J. Biol. Chem. 118, 531-537.
8. [8] Czaky, T.Z. (1984) On the estimation of bound hydroxylamine in biological materials. Act. Chem. Scand. 2, 450-454.
9. [9] Schwyn, B. and Neilands, J.B. (1987) Universal chemical assay for the detection and determination of siderophores. Anal. Biochem. 160, 47-56.
10. [10] Hu, X. and Boyer, G.L. (1995) Isolation and chatacterization of the siderophore N-schizokinen from Bacillus megaterium ATCC 19213. Biometals, 8, 357-364.
11. [11] Russel, L.M., Cryz Jr, S.J. and Holmes, R.K. (1984) Genetic and biochemical evidence for a siderophore-dependent iron transport in Corynebacterium diphtheriae. Infect. Immun. 45, 143-149.
12. [12] Winkelmann, G. (1986) Iron complex products. In: Biotechnology Vol. 4. (Rehm H.J., and Reed, G., Eds), pp. 215-243, Verlag Chemie, Weinheim.
13. [13] Konetschny-Rapp, S., Jung, G., Meiwes, J. and Zähner, H. (1990) Staphyloferrin A: a structurally new siderophore from staphylococci. Eur. J. Biochem. 191, 65-74.
14. [14] Haag, H., Fiedler, H.P., Meiwes, J., Drechsel, H., Jung, G. and Zähner, H. (1994) Isolation and characterization of Staphyloferrin B, a compound with siderophore activity from staphylococci. FEMS Microbiol. Lett. 115, 125-130.
15. [15] Marcelis, J.H, Den Daas-Slagt, H.J. and Hoogkamp-Korstanje, J.A.A. (1978) Iron requirement and chelator production of staphylococci S. faecalis, and enterobacteriaceae. Antonie van Leeuwenhoek 44, 257-267.
16. [16] Courcol, R.J., Lambert, P.A., Brown, M.R.W., Domingue, P.G. and Martin, G.R. (1988) Influence of iron-depletion on cellular proteins, antigenic profiles and siderophores of Staphylococcus aureus. In: Abstracts of the Annual Meeting of the American Society for Microbiology, Miami Beach, Fl, 1988. Abstract D-184, P. 101. American Society for Microbiology, Washington, D.C.
17. [17] Maskell, J.P. (1980) The functional interchangeability of enterobacterial and staphylococcal iron chelators. Antonie van Leeuwenhoek 46, 343-351.
18. [18] Miles, N.A. and Khimji, P.L. (1975) Enterobacterial chelators of iron: their occurrence, detection and relation to pathogenicity. J. Med. Microbiol. 8, 477-490.
19. [19] Trivier, D., Davril, M., Houdret, N. and Courcol, R.J. (1995) Influence of iron depletion on growth kinetics, siderophore production, and protein expression of Staphylococcus aureus. FEMS Microbiol. Lett. 127, 195-200.
20. [20] Courcol, R.J., Lambert, P.A., Fournier P., Martin, G.R. and Brown, M.R.W. (1991) Effects of iron depletion and sub-inhibitory concentrations of antibiotics on siderophore production by Staphylococcus aureus. J. Antimicrob. Chem. 28, 663-668.
21. [21] Meiwes, J., Fiedler, H.P., Haag, H., Zähner, H., Konetschny-Rapp, S. and Jung, G. (1990) Isolation and characterization of Staphyloferrin A, a compound with siderophore activity from Staphylococcus hyicus DSM 20459. FEMS Microbiol. Lett. 67, 201-206.
22. [22] Lisiecki, P., Tkacz B., Sobis, M. and Mikucki, J. (1994) The occurrence of siderophores in staphylococci. Acta Microbiol. Pol. 43, 21-31.
23. [23] Lindsay, J.A. and Riley, T.V. (1994) Staphylococcal iron requirements, siderophore production, and iron-regulated protein expression. Infect. Immun. 62, 2309-2314.
24. [24] Lindsay, J.A., Riley, T.V. and Mee B.J. (1994) Production of siderophore by coagulase-negative staphylococci and its relation to virulence. Eur. J. Clin. Microbiol. Infect. Dis. 13, 1063-1066.
25. [25] Heuck, D., Beer, W. and Reissbrodt, R. (1995) Iron supply of staphylococci and of micrococci by α-ketoacids. J. Med. Microbiol. 43, 26-32.
26. [26] Williams, P., Denyer, S.P. and Finch R.G. (1988) Protein antigens of Staphylococcus epidermidis grown under iron-restricted conditions in human peritoneal dialysate. FEMS Microbiol. Lett. 50, 29-33.
27. [27] Smith, D.G.E., Wilcox M.H., Williams P., Finch, R.G. and Denyer S.P. (1991) Characterization of cell envelope proteins of Staphylococcus epidermidis cultured in human peritoneal dialysate. Infect. Immun. 59, 617-624.
28. [28] Griffiths, E. (1987) The iron-uptake systems of pathogenic bacteria. In: Iron and Infection: Molecular, Physiological and Clinical Aspects. (Bullen, J.J. and Griffiths, E., Eds), pp. 69-138. John Wiley and Sons, Chichester.
29. [29] Williams, P. and Griffiths E. (1992) Bacterial transferrin receptors - structure, function and contribution to virulence. Med. Microbiol. Immunol. 181, 301-322.
30. [30] Padda, J.S. and Schryvers, A.B. (1990) N-linked oligosaccharides of human transferrin are not required for binding to bacterial transferrin receptors. Infect. Immun. 58, 2972-2976.
31. [31] Alcantara, J., Yu, R.H. and Schryvers, A.B. (1993) The region of human transferrin involved in binding to bacterial transferrin receptors is localized in the C-lobe. Mol. Microbiol. 8, 1135-1143.
32. [32] Modun, B., Kendall, D. and Williams, P. (1994) Staphylococci express a receptor for human transferrin: identification of a 42-kilodalton cell wall transferrin-binding protein. Infect. Immun. 62, 3850-3858.
33. [33] Lindsay, J.A., Riley, T.V. and Mee, B.J. (1995) Staphylococcus aureus but not Staphylococcus epidermidis can acquire iron from transferrin. Microbiology 141, 197-203.
34. [34] Naidu, A.S., Miedzobrodzki, J., Musser, J.M., Rosdahl, V.T., Hedström, S.A. and Forsgren, A. (1991) Human lactoferrin binding in clinical isolates of Staphylococcus aureus. J. Med. Microbiol. 34, 323-328.
35. [35] Cheung, A.L and Fischetti V.A. (1988) Variation in the expression of cell wall proteins of Staphylococcus aureus grown on solid and liquid media. Infect. Immun. 56, 1061-1065.
36. [36] Naidu, A.S., Andersson, M. and Forsgren, A. (1992) Identification of a human lactoferrin-binding protein in Staphylococcus aureus J. Med. Microbiol. 36, 177-183.
37. [37] Alcantara, J., Padda, J.S. and Schryvers, A.B. (1992) N-linked oligosaccharides of human lactoferrin are not required for binding to bacterial transferrin receptors. Can. J. Microbiol. 38, 1202-1205.
38. [38] Francis Jr, R.T., Booth, J.W. and Becker, R.R. (1984) Uptake of iron from hemoglobin and the haptoglobin-hemoglobin complex by hemolytic bacteria. Int. J. Biochem. 17, 767-773.
39. [39] Kornblum, J., Kreiswirth, B.N., Projan, S.J., Ross, H., and Novick, R.P. (1990) Agr: a polycystronic locus regulating exoprotein synthesis in Staphylococcus aureus. In Molecular Biology of the Staphylococci, (R.P. Novick, Ed.), pp. 373-402. VCH Publishers, New York.
40. [40] Salamah, A.A. (1992) Association of coagulase and/or pigmentation with the virulence of a capsule-lacking Staphylococcus aureus in iron-compromised mice. Microbiologica 15, 75-78.
41. [41] Deighton, M. and Borland. R. (1993) Regulation of slime production in Staphylococcus epidermidis by iron limitation. Infect. Immun. 61, 4473-4479.
42. [42] Baselga, R., Albizu, I., de la Cruz, M., Del Cacho, E., Barberan, M. and Amorena, B. (1993) Phase variation of slime production in Staphylococcus aureus: implications in colonization and virulence. Infect. Immun. 61, 4857-4862.
43. [43] Domingue, P.A.G., Lambert, P.A. and Brown, M.R.W. (1989) Iron depletion alters surface-associated properties of Staphylococcus aureus and its association to human neutrophils in chemiluminescence. FEMS Microbiol. Lett. 59, 265-268.
44. [44] Litwin, C.M. and Calderwood, S.B. (1993) Role of iron in regulation of virulence genes. Clin. Microbiol. Rev. 6, 137-149.
45. [45] Cheung, A.L., Wolz, C., Yeaman, M.R. and Bayer, A.S. (1995) Insertional inactivation of a chromosomal locus that modulates expression of potential virulence determinants in Staphylococcus aureus. J. Bacteriol. 177, 3220-3226.
46. [46] Schmitt, M.P. and Holmes, R.K. (1991) Iron-dependent regulation of diphtheria toxin and siderophore expression by the cloned Corynebacterium diphtheriae repressor gene dtxR in C. diphtheriae C7 strains. Infect. Immun. 59, 1899-1904.
47. [47] Cheung, A.L. and Ying, P. (1994) Regulation of α- and β-hemolysins by the sar locus of Staphylococcus aureus. J. Bacteriol. 176, 580-585.
48. [48] Cheung, A.L. and Projan, S.J. (1994) Cloning and sequencing of sar A of Staphylococcus aureus, a gene required for the expression of agr. J. Bacteriol. 176, 4168-4172.
49. [49] Patel, A.H., Kornblum, J., Kreiswirth, B., Novick, R. and Foster, T.J. (1992) Regulation of the protein A-encoding gene in Staphylococcus aureus. Gene 114, 25-34.
50. [50] Lissolo, L., Maitre-Wilmotte, G., Dumas, P., Mignon, M., Danve, B. and Quentin-Millet, M.-J. (1995) Evaluation of transferrin-binding protein 2 within the transferrin-binding protein complex as a potential antigen for future meningococcal vaccines. Infect. Immun. 63, 884-890.
51. [51] Brochu, A., Brochu, N., Nicas, T.I., Parr, T.R., Minnick, Jr. A.A., Dolence, Jr. E.K., Mc Kee, J.A., Miller, M.J., Lavoie, M.C. and Malouin, F. (1992) Modes of action and inhibitory activities of new siderophore-β-lactam conjugates that use specific iron uptake pathways for entry into bacteria. Antimicrob. Agents Chemother. 36, 2166-2175.