Brain ionized magnesium and calcium levels during magnesium supplementation and deficiency in female Long-Evans rats

Obstetrics and Gynecology

Volumn 88, Issue 2, 1996, Pages 184-188

  Standley, Cynthia A ^a,b   Cotton, David B ^a  

^a HUTZEL HOSPITAL   (United States)

^b Mott Center for Human Growth and Development   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM ION; MAGNESIUM ION; MAGNESIUM SULFATE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN LEVEL; CALCIUM BLOOD LEVEL; CEREBELLUM; CEREBROSPINAL FLUID LEVEL; CONTROLLED STUDY; ELECTROLYTE BLOOD LEVEL; FEMALE; HIPPOCAMPUS; HYPERMAGNESEMIA; HYPOMAGNESEMIA; INTRAPERITONEAL DRUG ADMINISTRATION; MAGNESIUM BLOOD LEVEL; MAGNESIUM DEFICIENCY; MINERAL BALANCE; NONHUMAN; PARIETAL LOBE; PRIORITY JOURNAL; RAT;

EID: 0030221805     PISSN: 00297844     EISSN: None     Source Type: Journal    
DOI: 10.1016/0029-7844(96)00144-5     Document Type: Article

References (22)

1. 1. Altura BM, Altura BT, Carella A. Magnesium deficiency-induced spasms of umbilical vessels: Relation to preeclampsia, hypertension, growth retardation. Science 1983;221:376-8.
2. 2. Altura BM, Altura BT, Gebrewold A. Magnesium deficiency and hypertension: Correlation between magnesium deficient diets and microcirculatory changes in situ. Science 1984;223:1315-7.
3. 3. Seydoux J. Serum and intracellular magnesium during normal pregnancy and in patients with pre-eclampsia. Br J Obstet Gynaecol 1992;99:207-11.
4. 4. Pritchard JA, Cunningham FG, Pritchard SA. The Parkland Memorial Hospital protocol for the treatment of eclampsia: Evaluation of 245 cases. Am J Obstet Gynecol 1984;148:951-63.
5. 5. Hallak M, Berman RF, Irtenkauf SM, Evans MI, Cotton DB. Peripheral magnesium sulfate enters the brain and increases the threshold for hippocampal seizures in rats. Am J Obstet Gynecol 1992;167:1605-10.
6. 6. Oppelt WW, MacIntryre I, Rall DP. Magnesium exchange between blood and cerebrospinal fluid. Am J Physiol 1963;205:959-62.
7. 7. Kato G, Smojen GG. Effects of micro-iontophoretic administration of magnesium and calcium on neurons in the central nervous system of cats. J Neurobiol 1969;2:181-95.
8. 8. Chutkow JG. Metabolism of magnesium in central nervous system. Relationship between concentrations of magnesium in cerebrospinal fluid and brain in magnesium deficiency. Neurology 1974;24: 180-7.
9. 9. Thurnau GR, Kemp DB, Jarvis A. Cerebrospinal fluid levels of magnesium in patients with preeclampsia after treatment with intravenous magnesium sulfate: A preliminary report. Am J Obstet Gynecol 1987;157:1435-8.
10. 10. Pritchard JA. The use of the magnesium ion in the management of eclamptic toxemias. Surg Gynecol Obstet 1995;100:131-40.
11. 11. Cotton DB, Janusz CA, Berman RF. Anticonvulsant effects of magnesium sulfate on hippocampal seizures: Therapeutic implications in preeclampsia-eclampsia. Am J Obstet Gynecol 1992;166: 1127-36.
12. 12. Standley CA, Irtenkauf SM, Mason BA, Cotton DB. Magnesium sulfate reduces seizures induced by central administration of the excitatory amino acid N-methyl-D-aspartate (NMDA) in rats. Hypertens Preg 1995;14:235-44.
13. 13. Wolf G, Fischer S, Hass P, Abicht K, Keilhoff G. Magnesium sulphate subcutaneously injected protects against kainate-induced convulsions and neurodegeneration: In vivo study on the rat hippocampus. Neuroscience 1991;43:31-4.
14. 2+ administered up to twenty-four hours following reperfusion prevents ischemic damage of the CA1 neurons in the rat hippocampus. Neuroscience 1991;44:335-41.
15. 15. Leaver DD, Parkinson GB, Schneider KM. Neurological consequences of magnesium deficiency: Correlations with epilepsy. Clin Exp Pharmacol Physiol 1987;14:361-70.
16. 16. Geven WB, Vogels-Mentink GM, Willems JL, Joordens UM, Hilbers CW, Monnens LAH. Experimental magnesium depletion in the dog: Relation between total and ultrafiltrable Mg in plasma and total and ionized Mg in erythrocytes. Magnes Bull 1990;12: 166-9.
17. 17. Fry CH. Measurement and control of intracellular magnesium ion concentration in guinea pig and ferret ventricular myocardium. Magnesium 1986;5:306-16.
18. 18. Parfitt AM, Kleerekoper M. Clinical disorders of calcium, phosphorus and magnesium metabolism. In: Maxwell MH, Kleeman CR, eds. Clinical disorders of fluid and electrolyte metabolism. 3rd ed. New York: McGraw-Hill, 1980:1092-151.
19. 19. Chutkow JG, Grabow JD. Clinical and chemical correlations in magnesium-deprivation encephalopathy of young rats. Am J Physiol 1972;223:1407-14.
20. 31P magnetic resonance spectroscopy and behavioral studies. J Neurotrauma 1988;5:17-31.
21. 21. Meyer JG, Urban K. Electrolyte changes and acid base balance after alcohol withdrawal, with special reference to rum fits and magnesium depletion. J Neurol 1977;215:135-40.
22. 22. Wolfe SM, Victor M. The relationship of hypomagnesemia and alkalosis to alcohol withdrawal symptoms. Ann N Y Acad Sci 1969;162:973-84.