Design and Synthesis of Gentiohexaosyl Derivatives for an ANP Receptor Antagonist, HS-142–1

Bioscience, Biotechnology and Biochemistry

Volumn 60, Issue 8, 1996, Pages 1308-1316

  Qiu, Yi ^a   Nakahara, Yoshiaki ^a   Ogawa, Tomoya ^a,b  

^a INST OF PHYS AND CHEMICAL RESEARCH   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

Author keywords

ANP antagonist; Gentiohexaose; HS 142 1; 1 6 glycosylation

Indexed keywords

ATRIAL NATRIURETIC FACTOR RECEPTOR; DISACCHARIDE; GENTIOBIOSE; HEXANOIC ACID DERIVATIVE; HS 142 1; OLIGOSACCHARIDE; POLYSACCHARIDE;

ARTICLE; CARBOHYDRATE ANALYSIS; CHEMISTRY; DRUG ANTAGONISM; DRUG DESIGN; MOLECULAR GENETICS; STRUCTURE ACTIVITY RELATION; SYNTHESIS;

CAPROATES; CARBOHYDRATE SEQUENCE; DISACCHARIDES; DRUG DESIGN; MOLECULAR SEQUENCE DATA; OLIGOSACCHARIDES; POLYSACCHARIDES; RECEPTORS, ATRIAL NATRIURETIC FACTOR; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0030221768     PISSN: 09168451     EISSN: 13476947     Source Type: Journal    
DOI: 10.1271/bbb.60.1308     Document Type: Article

References (13)

1. Y. Matsuda and Y. Morishita, Cardiovascular Drug Reviews, 11, 45-59 (1993).
2. Y. Saitoh and Y. Matsuda, personal communication.
3. Y. Qiu, Y. Nakahara, and T. Ogawa, Biosci. Biotech. Biochem., 60, 986-993 (1996).
4. C. A. A. van Boeckel and M. Petitou, Angew. Chem. Int. Ed. Engl. 32, 1671-1690 (1993).
5. K. Jansson, S. Ahlfors, T. Frejd, J. Kihlberg, G. Magnusson, J. Dahmén, G. Noori, and K. Stenvall, J. Org. Chem., 53, 5629-5647 (1988).
6. H. J. Koeners, J. Verhoeven, and J. H. van Boom, Reel. Trav. Chim. Pays-Bas, 100, 65-72 (1981).
7. P. J. Garegg and T. Norberg, Acta Chem. Scand. B, 33, 116-118 (1979).
8. R. Gigg and R. Conant, Carbohydr. Res., 100, C5-C9 (1982).
9. T. M. Slaghek, M. J. van Vilet, A. A. M. Maas, J. P. Kamerling, and J. F. G. Vliegenthart, Carbohydr. Res., 195, 75-86 (1989).
10. J. J. Oltvoort, C. A. A. van Boeckel, J. H. de Koning, and J. H. van Boom, Synthesis, 1981, 305-308.
11. O. Holsfi Angew. Chem. Int. Ed. Engl., 34, 2000-2002 (1995).
12. H. Kuyama, T. Nukada, Y. Ito, Y. Nakahara, and T. Ogawa, Carbohydr. Res., 268, C1-C6 (1995).
13. S. P. Douglas, D. M. Whitfield, and J. Krepinsky, J. Carbohydr. Chem., 12, 131-136 (1993).