Identification of the Fy6 epitope recognized by two monoclonal antibodies in the N-terminal extracellular portion of the duffy antigen receptor for chemokines

Molecular Immunology

Volumn 33, Issue 11-12, 1996, Pages 917-923

  Waśniowska, Kazimiera ^a   Blanchard, Dominique ^b   Janvier, Daniel ^c   Wang, Zi Xuan ^d   Peiper C, Stephen ^d   Hadley, Terence J ^e   Lisowska, Elwira ^a  

^a INSTITUTE OF IMMUNOLOGY AND EXPERIMENTAL THERAPY   (Poland)

^b Etablissement Transfus Sang L   (France)

^c Banque du Sang   (France)

^d UNIVERSITY OF LOUISVILLE   (United States)

^e University of Louisville School of Medicine   (United States)

Author keywords

Deletion mutagenesis; Duffy antigen; Fy6; Monoclonal antibodies; Peptides

Indexed keywords

BLOOD GROUP ANTIGEN; EPITOPE; MONOCLONAL ANTIBODY;

ARTICLE; BLOOD GROUP DUFFY SYSTEM; FLOW CYTOMETRY; HUMAN; MUTANT; PRIORITY JOURNAL; SITE DIRECTED MUTAGENESIS;

AMINO ACID SEQUENCE; ANIMALS; ANTIBODIES, MONOCLONAL; ANTIBODIES, PROTOZOAN; ANTIGENS, PROTOZOAN; CARRIER PROTEINS; CHEMOKINES; DUFFY BLOOD-GROUP SYSTEM; EPITOPES; MEMBRANE PROTEINS; MOLECULAR SEQUENCE DATA; PLASMODIUM; PROTEIN BINDING; PROTEIN CONFORMATION; PROTOZOAN PROTEINS; RECEPTORS, CELL SURFACE;

EID: 0030221701     PISSN: 01615890     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0161-5890(96)00056-9     Document Type: Article

References (24)

1. Ali S. A. and Steinkasserer A. (1995) PCR ligation - PCR mutagenesis: a protocol for creating gene fusions and mutations. BioTechniques 18, 746-750.
2. Barnwell J. W., Nichols M. E. and Rubinstein P. (1989) In vitro evaluation of the role of the Duffy blood group in Plasmodium vivax erythrocyte invasion. J. exp. Med. 169, 162-167.
3. Chaudhuri A., Poyakova J., Zbrzezna V., Williams K., Gulati S. and Pogo A. O. (1993) Cloning of glycoprotein D cDNA, which encodes the major subunit of the Duffy blood group system and the receptor for the Plasmodium vivax malaria parasite. Proc. natn. Acad. Sci. U.S.A. 90, 10793-10797.
4. Chaudhuri A., Poyakova J., Zbrzezna V. and Pogo A. O. (1995) The coding sequence of Duffy blood group gene in humans and simians: restriction fragment length polymorphism, antibody and malarial parasite specificities, and expression in nonerythroid tissues in Duffy-negative individuals. Blood 85, 615-621.
5. Geysen H. M., Rodda S. J., Mason T. J., Tribbick G. and Schoofs P. G. (1987) Strategies for epitope analysis using peptide synthesis. J. Immunol. Methods 102, 259-274.
6. Hadley, T. J. and Miller, L. H. (1992) Red cell antigens as receptors for malaria parasites. In Protein Blood Group Antigens of the Human Red Cell: Structure, Function, and Clinical Signifance (Edited by Agre P. and Cartron J.P.), pp. 228-245. Johns Hopkins University Press, Baltimore, MD.
7. Hadley T. J., Lu Z.-H., Waśniowska K., Martin A. W., Peiper S. C., Hesselgesser J., Horuk R. (1994) Postcapillary venule endothelial cells in kidney express a multispecific chemokine receptor that is structurally and functionally identical to the erythroid isoform which is the Duffy blood group antigen. J. clin. Invest. 94, 985-991.
8. Hausman E., Dzik W. and Blanchard D. (1996) The red cell chemokine receptor is distinct from the Fy6 epitope. Transfusion 36, 421-425.
9. Horuk R. (1994) The interleukin-8-receptor family: from chemokines to malaria. Immunol. Today 15, 169-174.
10. Horuk R., Chitnis C. E., Darbonne W. C., Colby T. J., Rybicki A., Hadley T. J. and Miller L. H. (1993) A receptor for the malarial parasite Plasmodium vivax: the erythrocyte chemokine receptor. Science 261, 1182-1184.
11. b alloantigen system is associated with a polymorphism at the 44-amino acid residue. Blood 85, 622-626.
12. Lu Z.-H., Wang Z.-X., Horuk R., Hesselgesser J., Lou Y.-C., Hadley T. J. and Peiper S. C. (1995) The promiscous chemokine binding profile of the Duffy antigen/receptor for chemokines is primarly localized to sequences in the amino-terminal domain. J. biol. Chem 270, 26239-26245.
13. b antigens and identification of a deletion in the Duffy gene of an apparently healthy individual with the Fy(a-b-) phenotype. Br. J. Haematol. 90, 823-829.
14. Miller L. H., Mason S. J., Dvorak J. A., McGinniss M. H. and Rothman I. K. (1975) Erythrocyte receptors for (Plasmodium knowlesi) malaria: Duffy blood determinants. Science 189, 561-563.
15. Miller L. H., Mason S. J., Clyde D. F. and McGinnis M. H. (1976) The resistance factor to Plasmodium vivax in blacks. The Duffy blood group genotype FyFy. New Engl. J. Med. 295, 302-304.
16. Neote K., Mak J. Y., Kolakowski L. F. and Schall T. J. (1994) Functional and biochemical analysis of the cloned Duffy antigen: identity with the red blood cell chemokine receptor. Blood 84, 44-52.
17. Nichols M. E., Rubinstein P., Barnwell J., Rodriguez de Cordoba S. and Rosenfield R. E. (1987) A new human Duffy blood group specificity defined by a murine monoclonal antibody. J. exp. Med. 166, 776-785.
18. Peiper S. C., Wang Z.-X., Neote K., Martin A. S., Showell H. J., Conklyn M. J., Hadley T. J., Lu Z.-H., Hesselgesser J. and Horuk R. (1995) The Duffy antigen/receptor for chemokines (DARC) is expressed in endothelial cells of Duffy negative individuals who lack the erythrocyte receptor. J. exp. Med. 181, 1311-1317.
19. Riwom S., Janvier D., Navenot J. M., Benbunan M., Muller J. Y. and Blanchard D. (1994) Production of a new murine monoclonal antibody with Fy6 specificity and characterization of the immunopurified N-glycosylated Duffy-active molecule. Vox Sang. 66, 61-67.
20. Szabo M. C., Soo K. S., Zlotnik A. and Schall T. J. (1995) Chemokine class differences in binding to the Duffy antigen/erythrocyte receptor. J. biol. Chem. 270, 25348-25351.
21. Tournamille C., Colin Y., Cartron J. P. and Le Van Kim C. (1995) Disruption of a GATA motif in the Duffy gene promoter abolishes erythroid gene expresion in Duffy-negative individuals. Nature Genet. 10, 224-228.
22. Waśniowska K. and Hadley T. J. (1994) The Duffy blood group antigen: an update. Transfusion Medicine Rev. 8, 281-288.
23. Waśniowska K., Duk M., Czerwiński M., Steuden I., Duś D., Radzikowski C., Bartosz-Bechowski H., Konopińska D. and Lisowska E. (1992) Analysis of peptidic epitopes recognized by the three monoclonal antibodies specific for the same region of glycophorin A but showing different properties. Molec. Immunol. 29, 783-791.
24. Waśniowska K., Eichenberger P., Kugele F. and Hadley T. J. (1993) Purification of a 28 kD non-aggregating tryptic peptide of the Duffy blood group protein. Biochem. Biophys. Res. Commun. 192, 366-372.