Epstein-barr virus in Hodgkin's disease

Seminars in Cancer Biology

Volumn 7, Issue 4, 1996, Pages 183-189

  Herbst, Hermann ^a  

^a UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

Author keywords

Epstein Barr virus; Gene expression; Hodgkin's disease; Latent membrane protein; Virus specific immunity

Indexed keywords

CD30 ANTIGEN; DIFFERENTIATION ANTIGEN; VIRUS PROTEIN;

ARTICLE; EPISOME; EPSTEIN BARR VIRUS; GENOTYPE; HODGKIN DISEASE; HUMAN; NONHUMAN; PHENOTYPE; VIRUS IMMUNITY;

EID: 0030221665     PISSN: 1044579X     EISSN: None     Source Type: Journal    
DOI: 10.1006/scbi.1996.0025     Document Type: Article

References (68)

1. 1. Lukes RJ, Butler JJ (1966) The pathology and nomenclature of Hodgkin's disease. Cancer Res 26:1063-1081
2. 2. Harris NL, Jaffe E, Stein H, Banks PM, Chan J, Cleary ML, Delsol G, de Wolf-Peeters C, Falini B, Gatter K, Grogan TM, Isaacson PG, Knowles DM, Mason DY, Müller-Hermelink HK, Pileri S, Piris MA, Ralfkiaer E, Warnke R (1994) A revised European-American classification of lymphoid neoplasms: A proposal from the International Lymphoma Study Group. Blood 84:1361-1392
3. 3. Drexler HG (1992) Recent results on the biology of Hodgkin and Reed-Sternberg cells. I. Biopsy Material. Leuk Lymphoma 8:283-313
4. 4. Herbst H, Niedobitek G, Stein H (1993) Epstein-Barr virus and CD30-positive malignant lymphomas. Crit Rev Oncogenesis 4:191-239
5. 5. Haluska FG, Brufsky AM, Canellos GP (1994) The cellular biology of the Reed-Sternberg cell. Blood 84:1005-1019
6. 6. Küppers R, Rajewski K, Zhao M, Simons G, Laumann R, Fischer R, Hansmann ML (1994) Hodgkin's disease: Hodgkin and Reed-Sternberg cells picked from histological sections show clonal immunoglobulin gene rearrangements and appear to be derived from B cells at various stages of development. Proc Natl Acad Sci USA 91:10962-10966
7. 7. Stein H, Mason DY, Gerdes J, O'Connor N, Wainscoat J, Pallesen G, Gatter K, Falini B, Delsol G, Lemke H, Schwarting R, Lennert K (1985) The expression of Hodgkin's disease-associated antigen Ki-1 in reactive and neoplastic lymphoid tissue. Evidence that Reed-Sternberg cells and histiocytic malignancies are derived from activated lymphoid cells. Blood 66:848-858
8. 8. Gutensohn NM, Cole P (1980) Epidemiology of Hodgkinson's disease. Semi: in Oncol 7:92-102
9. 9. Mueller N, Evans A, Harris NL, Comstock GW, Jellum E, Magnus K, Orentreich N, Polk F, Vogelman J (1989) Hodgkin's disease and Epstein-Barr virus. Altered antibody pattern before diagnosis. N Engl J Med 320:689-695
10. 10. Weiss LM, Strickler JG, Warnke RA, Purtilo DT, Sklar J (1987) Epstein-Barr viral DNA in tissues of Hodgkin's disease. Am J Pathol 129:86-91
11. 11. Herbst H, Tippelmann G, Anagnostopoulos I, Gerdes J, Schwarting R, Boehm T, Pileri S, Jones DB, Stein H (1989) Immunoglobulin and T cell receptor gene rearrangements in Hodgkin's disease and Ki-1-positive anaplastic large cell lymphoma: Dissociation between genotype and phenotype. Leuk Res 13:103-116
12. 12. Weiss LM, Movahed AM, Warnke RA, Sklar J (1989) Detection of Epstein-Barr viral genomes in Reed-Sternberg cells of Hodgkin's disease. N Engl J Med 320:502-506
13. 13. Anagnostopoulos I, Herbst H, Niedobitek G, Stein H (1989) Demonstration of monoclonal EBV genomes in Hodgkin's disease and Ki-1-positive anaplastic large cell lymphoma by combined Southern and in situ hybridization. Blood 74:810-816
14. 14. Staal SP, Ambinder R, Beschorner WE, Hayward G, Mann R (1989) A survey of Epstein-Barr virus DNA in lymphoid tissue. Frequent detection in Hodgkin's disease. Am J Clin Pathol 91:1-5
15. 15. Uccini S, Monardo F, Stoppaccioro A, Gradilone A, Aglianò AM, Maggioni A, Manzari V, Vago L, Costanzi G, Ruco LP, Baroni C (1990) High frequency of Epstein-Barr virus genome detection in Hodgkin's disease of HIV-positive patients. Int J Cancer 46:581-585
16. 16. Brousset P, Chittal S, Schlaifer D, Icart J, Payen C, Rigal-Huguet F, Voigt JJ, Delsol G (1991) Detection of Epstein-Barr virus messenger RNA in Reed-Stern berg cells of Hodgkin's disease by in situ hybridization with biotinylated probes on specially processed modified acetone methyl benzoate xylene (ModAMeX) sections. Blood 77:1781-1786
17. 17. Herbst H, Niedobitek G, Kneba M, Hummel M, Finn T, Anagnostopoulos I, Bergholz M, Krieger G, Stein H (1990) High incidence of Epstein-Barr virus genomes in Hodgkin's disease. Am J Pathol 137:13-18
18. 18. Gledhill S, Gallagher A, Jones DB, Krajewski AS, Alexander FE, Klee E, Wright DH, O'Brien C, Onions DE, Jarrett RF (1991) Viral involvement in Hodgkin's disease: detection of clonal type A Epstein-Barr virus genomes in tumour samples. Br J Cancer 64:227-232
19. 19. Knecht H, Odermatt BF, Bachmann E, Teixeira S, Sahli R, Hayoz D, Heitz P, Bachmann F (1991) Frequent detection of Epstein-Barr virus DNA by the polymerase chain reaction in lymph node biopsies from patients with Hodgkin's disease without genomic evidence of B-or T-cell clonality. Blood 78:760-767
20. 20. Weiss LM, Chen YY, Liu XE, Shibata D (1991) Epstein-Barr virus and Hodgkin's disease. A correlative in situ hybridization and polymerase chain reaction study. Am J Pathol 139:1259-1265
21. 21. Boyle MJ, Vasak E, Tschuchnigg M, Turner JJ, Sculley T, Penny R, Cooper DA, Tindall B, Sewell WA (1993). Subtypes of Epstein-Barr virus (EBV) in Hodgkin's disease: Association between B-type EBV and immunocompromise. Blood 81:468-474
22. 22. Knecht H, Bachmann E, Brousset P, Sandvej K, Nadal D, Bachmann F, Odermatt BF, Delsol G, Pallesen G (1993). Deletions without the LMP1 oncogene of Epstein-Barr virus are clustered in Hodgkin's disease and identical to those observed in nasopharyngeal carcinoma. Blood 82:2937-2942
23. 23. Herbst H, Steinbrecher E, Niedobitek G, Young LS, Brooks L, Muller-Lantzsch, Stein H (1992) Distribution and phenotype of Epstein-Barr virus-harboring cells in Hodgkin's disease. Blood 80:484-491
24. 24. Hummel M, Anagnostopulos I, Dallenbach F, Korbjuhn P, Dimmler C, Stein H (1992) EBV infection patterns in HD and normal lymphoid tissue: expression and cellular localization of EBV gene products. Br J Haematol 82:689-694
25. 25. Preciado MV, De-Matteo E, Diez B, Menarguez J, Grinstein S (1995) Preciado Presence of Epstein-Barr virus and strain type assignment in Argentine childhood Hodgkin's disease. Blood 86:3922-3929
26. 26. Zhu ZG, Hamilton-Dutoit S, Yan QH, Pallesen G (1993) The association between Epstein-Barr virus and Chinese Hodgkin's disease. Int J Cancer 55:359-363
27. 27. Huh J, Park C, Juhng S, Kim CE, Poppema S, Kim C (1996) A pathologic study of Hodgkin's disease in Korea and its association with the Epstein-Barr virus infection. Cancer 77:949-955
28. 28. Belkaid MI, Briere J, Djebbara Z, Beldjord K, Andrieu JM, Colonna P (1995) Comparison of Epstein-Barr virus markers in Reed-Sternberg cells in adult Hodgkin's disease tissues from an industrialized and a developing country. Leuk Lymphoma 17:163-168
29. 29. Quintanilla-Martinez L, Gamboa-Domnquez A, Gamez-Ledesma I, Angeles-Angeles A, Mohar A (1995) Association of Epstein-Barr virus latent membrane protein and Hodgkin's disease in Mexico. Mod Pathol 8:675-679
30. 30. Chang KL, Albujar PF, Chen YY, Johnson RM, Weiss LM (1993) High prevalence of Epstein-Barr virus in the Reed-Sternberg cells of Hodgkin's disease occurring in Peru. Blood 81:496-501
31. 31. Ambinder RF, Brownin PJ, Lorenzana I, Leventhal BG, Cosenza H, Mann RB, MacMahon EME, Medina R, Cardona V, Grufferman S, Olshan A, Levin A, Petersen EA, Blattner W, Levine PH (1992) Epstein-Barr virus and childhood Hodgkin's disease in Honduras and the United States. Blood 81:462-467
32. 32. Siebert JD, Ambinder RF, Napoli VM, Quintanilla-Martinez L, Banks PM, Gulley ML (1995) Human immunodeficiency virus-associated Hodgkin's disease contains latent, not replicative, Epstein-Barr virus. Hum Pathol 26:1191-1195
33. 33. Herbst H, Dallenbach F, Hummel M, Niedobitek G, Rowe M, Young LS, Muller-Lantzsch N, Stein H (1991). Epstein-Barr virus DNA and latent gene products in CD30-positive anaplastic large cell lymphomas. Blood 78:2666-2673
34. 35. Carbone A, Gloghini A, Volpe R, Boiocchi M, Tirelli U (1994) High frequency of Epstein-Barr virus latent membrane protein-1 expression in acquired immunodeficiency syndrome-related Ki-1 (CD30)-positive anaplastic large-cell lymphomas. Italian Cooperative Group on AIDS and Tumors. Am J Clin Pathol 101:768-772
35. 36. Gulley ML, Eagan PA, Quintanilla-Martinez L, Picado AL, Smir BN, Childs C, Dunn CD, Craig FE, Williams JW Jr, Banks PM (1994) Epstein-Barr virus DNA is abundant and monoclonal in the Reed-Sternberg cells of Hodgkin's disease: association with mixed cellularity subtype and Hispanic American ethnicity. Blood 83:1595-1602
36. 37. Boiocchi M, Dolcetti R, De Re V, Gloghini A, Carbone A (1993) Demonstration of a unique Epstein-Barr virus-positive cellular clone in metachronous multiple localizations of Hodgkin's disease. Am J Pathol 142:33-38
37. 38. Vasef MA, Kamel OW, Chen YY, Medeiros LJ, Weiss LM (1995) Detection of Epstein-Barr virus in multiple sites involved by Hodgkin's disease. Am J Pathol 147:1408-1415
38. 39. Brousset P, Schlaifer D, Meggetto F, Bachmann E, Rotheberger S, Pris J, Delsol G, Knecht H (1994) Persistence of the same viral strain in early and late relapses of Epstein-Barr virus-associated Hodgkin's disease. Blood 84:2447-2451
39. 40. Hummel M, Ziemann K, Lammert H, Pileri S, Sabattini E, Stein H (1995) Hodgkin's disease with monoclonal and polyclonal populations of Reed-Sternberg cells. New Engl J Med 333:901-906
40. 41. Niedobitek G, Herbst H, Young LS, Brooks L, Masucci MG, Crocker J, Rickinson AB, Stein H (1992) Patterns of Epstein-Barr virus infection in non-neoplastic lymphoid tissue. Blood 79:2520-2526
41. 42. Herbst H, Dallenbach F, Hummel M, Niedobitek G, Pileri S, Muller-Lantzsch N, Stein H (1991) Epstein-Barr virus latent membrane protein expression in Hodgkin and Reed-Sternberg cells. Proc Natl Acad Sci USA 88:4766-4770
42. 43. Pallesen G, Hamilton-Dutoit SJ, Rowe M, Young LS (1991) Expression of Epstein-Barr virus latent gene products in tumour cells of Hodgkin's disease. Lancet 337:320-322
43. 44. Grässer FA, Murray PG, Kremmer E, Klein K, Remberger K, Feiden W, Reynolds G, Niedobitek G, Young LS, Mueller-Lantzsch N (1994) Monoclonal antibodies directed against the Epstein-Barr virus-encoded nuclear antigen 1 (EBNA1): immunohistologic detection of EBNA1 in the malignant cells of Hodgkin's disease. Blood 84:3792-3798
44. 45. Deacon EM, Pallesen G, Niedobitek G, Crocker J, Brooks L, Rickinson AB, Young LS (1992) Epstein-Barr virus and Hodgkin's disease: Transcriptional analysis of virus latency in the malignant cells. J Exp Med 177:339-349
45. 46. Pallesen G, Sandvej K, Hamilton-Dutoit SJ, Rowe M, Young LS (1991) Activation of Epstein-Barr virus replication in Hodgkin and Reed-Sternberg cells. Blood 78:1162-1165
46. 47. Brousset P, Knecht H, Rubin B, Drouet E, Chittal S, Meggetto F, Saati TA, Bachmann E, Denoyel G, Sergeant A, Delsol G (1993) Demonstration of Epstein-Barr virus replication in Reed-Sternberg cells of Hodgkin's disease. Blood 82:872-876
47. 48. Herbst H, Raff T, Stein H (1996) Phenotypic modulation of Hodgkin and Reed-Sternberg cells by Epstein-Barr virus. J Pathol 179:54-59
48. 49. Bai MC, Jiwa NM, Horstman A, Vos W, Kluin PH, Van-der-Valk P, Mullink H, Walboomers JM, Meijer CJ (1994) Decreased expression of cellular markers in Epstein-Barr virus-positive Hodgkin's disease. J Pathol 174:49-55
49. 50. Foss HD, Herbst H, Oelmann E, Samol J, Blankenstein T, Matthes J, Qin ZH, Falini B, Pileri S, Diamantstein T, Stein H (1993) Lymphotoxin, tumour necrosis factor and interleukin-6 RNA are present in Hodgkin and Reed-Sternberg cells of most Hodgkin's disease cases. Br J Haematol 84:627-635
50. 51. Herbst H, Foss HD, Samol J, Araujo I, Klotzbach H, Krause H, Agathanggelou A, Niedobitek G, Stein H (1996) Frequent expression of interleukin-10 in Epstein-Barr virus-harboring tumor cells of Hodgkin's disease. Blood 87:2918-2929
51. 52. Foss HD, Herbst H, Hummel M, Latza U, Rancsò C,. Anagnostopoulos I, Dallenbach F, Smith H (1994) Patterns of cytokine gene expression in infectious mononucleosis. Blood 83:707-712
52. 53. Rowe M, Peng-Pilon M, Huen DS, Hardy R, Croom-Carter D, Lundgren E, Rickinson AB (1994) Upregulation of bcl-2 by the Epstein-Barr virus latent membrane protein LMP-1: a B-cell-specific response that is delayed relative to NF-(Greek small letter script kappa)B activation and to induction of cell surface markers. J Virol 68:5602
53. 54. Mori N, Shirakawa F, Shimizu F, Murakami S, Oda S, Yamamoto KI, Eto S (1994) Transcriptional regulation of the human interleukin-6 gene promoter in human T-cell leukemia virus type I-infected T-cell lines: evidence for the involvement of NF-(Greek small letter scipt kappa)B. Blood 84:2904-2911
54. 55. Momose H, Jaffe ES, Shin SS, Chen YY, Weiss LM (1993) Chronic lymphocytic leukemia/ small lymphocytic lymphoma with Reed-Sternberg-like cells and possible transformation to Hodgkin's disease. Mediation by Epstein-Barr virus. Am J Surg Pathol 16:859-867
55. 56. Khan G, Norton AJ, Slavin G (1993) Epstein-Barr virus in Reed-Stern berg-like cells in non-Hodgkin's lymphomas. J Pathol 169:9-14
56. 57. Isaacson PG, Schmid C, Pan L, Wotherspoon AC, Wright DH (1992) Epstein-Barr virus latent membrane protein expression by Hodgkin and Reed-Sternberg-like cells in acute infectious mononucleosis. J Pathol 167:267-271
57. 58. Reynolds DJ, Banks PM, Gulley ML (1995) New characterization of infectious mononucleosis and a phenotypic comparison with Hodgkin's disease. Am J Pathol 146:379-388
58. 59. O'Grady J, Stewart S, Elton RA, Krajewski AS (1994) Epstein-Barr virus in Hodgkin's disease and site of origin of tumour. Lancet 343:265-266
59. 60. Kapadia SB, Roman LN, Kingma DW, Jaffe ES, Frizzera G (1995) Hodgkin's disease of Waldeyer's ring. Clinical and histoimmunophenotypic findings and association with Epstein-Barr virus in 16 cases. Am J Surg Pathol 19:1431-1439
60. 61. Murray RJ, Wang D, Young LS, Wang F, Rowe M, Kieff E, Rickinson AB (1988) Epstein-Barr virus-specific cytotoxic T-cell recognition of transfectants expressing the virus-encoded latent membrane protein LMP. J Virol 62:3747-3755
61. 62. Thorley-Lawson DA, Israelsohn ES (1987) Generation of specific cytotoxic T cells with a fragment of the Epstein-Barr virus-encoded p63/ latent membrane protein. Proc Natl Acad Sci USA 84:5384-5388
62. 63. Klein G (1989) Viral latency and transformation: The strategy of Epstein-Barr virus. Cell 58:5-8
63. 64. Chen HS, Kevan-Jah S, Sünzenich KO, Grässer FA, Müller-Lantzsch N (1992) Expression of the Epstein-Barr virus latent membrane protein (LMP) in insect cells and detection of antibodies in human sera against this protein. Virology 190:106-115
64. 65. Frisan T, Sjöberg J, Dolcetti R, Boiocchi M, De-Re V, Carbone A, Brautbar C, Battat S, Biberfeld P, Eckman M, Öst A, Christensson B, Sundström C, Björkholm M, Pisa P, Masucci MG (1995) Local suppression of Epstein-Barr virus (EBV)-specific cytotoxicity in biopsies of EBV-positive Hodgkin's disease. Blood 86:1493-1501
65. 66. Mosialos G, Birkenbach M, Yalamanchili R, Van Arsdale T, Ware C, Kieff E (1995) The Epstein-Barr virus transforming protein LMP1 engages signaling proteins for the tumor necrosis factor receptor family. Cell 80:389-399
66. 67. Vestlev PM, Pallesen G, Sandvej K, Hamilton-Dutoit SJ, Bendtzen SM (1992) Prognosis of Hodgkin's disease is not influenced by Epstein-Barr virus latent membrane antigen. Int J Cancer 50:670-671
67. 68. Henderson S, Rowe M, Croom-Carter D, Wang F, Longnecker L, Kieff E, Rickinson A (1991) Induction of bcl-2 expression by Epstein-Barr virus latent membrane protein 1 protects infected B cells from programmed cell death. Cell 65:1107-1115
68. 69. Oudejans JJ, Kummer JA, Jiwa M, van-der-Valk P, Ossenkoppele GJ, Kluin PM, Kluin-Nelemans JC, Meijer CJ (1996) Granzyme B expression in Reed-Sternberg cells of Hodgkin's disease. Am J Pathol 148:233-240