Cytoskeletal inhibitors impair Ca2+ elevations via neuropeptide Y and other G(i)-coupled receptors

European Journal of Pharmacology

Volumn 309, Issue 1, 1996, Pages 87-94

  Michel, Martin C ^a,b   Kaldenberg Stasch, Sylvia ^a   Wieland, Thomas ^a  

^a UNIVERSITY OF DUISBURG ESSEN   (Germany)

^b UNIVERSITY HOSPITAL ESSEN   (Germany)

Author keywords

Ca2+; G(i) protein; Microfilament; Microtubule; Neuropeptide Y receptor; (2) Adrenoceptor

Indexed keywords

ADRENALIN; ALPHA 2A ADRENERGIC RECEPTOR; BETA LUMICOLCHICINE; CALCIUM; CARBACHOL; COLCHICINE; CYTOCHALASIN B; CYTOCHALASIN D; GUANOSINE 5' O (3 THIOTRIPHOSPHATE); INHIBITORY GUANINE NUCLEOTIDE BINDING PROTEIN; IODINE 125; MUSCARINIC RECEPTOR; NEUROPEPTIDE Y; NEUROPEPTIDE Y RECEPTOR; NOCODAZOLE; PEPTIDE YY; PROTEIN SUBUNIT; RADIOISOTOPE; THROMBIN; THROMBIN RECEPTOR; UNCLASSIFIED DRUG; VINBLASTINE;

ARTICLE; CALCIUM CELL LEVEL; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOSKELETON; DRUG RECEPTOR BINDING; ERYTHROLEUKEMIA CELL; HUMAN; HUMAN CELL; IMMUNOBLOTTING; MICROFILAMENT; MICROTUBULE; NEUROBLASTOMA CELL; PRIORITY JOURNAL;

EID: 0030221662     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/0014-2999(96)00331-7     Document Type: Article

References (17)

1. Brass, L.F., D.R. Manning, A.G. Williams, M.J. Woolkalis and M. Poncz, 1991, Receptor and G protein-mediated responses to thrombin in HEL cells, J. Biol. Chem. 266, 958.
2. 1-like neuropeptide Y receptors in SK-N-MC cells, Naunyn-Schmiedeberg's Arch. Pharmacol. 344, 1.
3. Feth, F., W. Rascher and M.C. Michel, 1992, Neuropeptide Y (NPY) receptors in HEL cells: comparison of binding and functional parameters for full and partial agonists and a non-peptide antagonist, Br. J. Pharmacol. 105, 71.
4. Jasper, J.R., S.R. Post, K.H. Desai, P.A. Insel and D. Bernstein, 1995, Colchicine and cytochalasin B enhance cyclic AMP accumulation via postreceptor actions, J. Pharmacol. Exp. Ther. 274, 937.
5. Kammer, G.M., 1988, The adenylate cyclase-cAMP-protein kinase A pathway and regulation of immune response, Immunol. Today 9, 222.
6. Komuro, I. and Y. Yzaki, 1994, Intracellular signaling pathways in cardiac myocytes induced by mechanical stress, Trends Cardiovasc. Med. 4, 117.
7. s-mediated signal transduction in S49 lymphoma cells treated with inhibitors of microtubules, J. Biol. Chem. 268, 3833.
8. 2+ in human erythroleukemia cells, J. Biol. Chem. 264, 4986.
9. 2+ mobilization by NPY, Naunyn-Schmiedeberg's Arch. Pharmacol. 345, 370.
10. Michel-Reher, M., G. Gross, J.R. Jasper, D. Bernstein, T. Olbricht, O.-E. Brodde and M.C. Michel, 1993. Tissue-and subunit-specific regulation of G-protein expression by hypo-and hyperthyroidism, Biochem. Pharmacol. 45, 1417.
11. ++ and inhibits adenylate cyclase in human erythroleukemia cells, Am. J. Physiol. 255, E880.
12. Peters, R. 1988, Lateral mobility of proteins and lipids in the red cell membrane and the activation of adenylate cyclase by β-adrenergic receptors, FEBS Lett. 234, 1.
13. αs that interact with tubulin for β-adrenergic activation of adenylyl cyclase, J. Biol. Chem. 269, 21748.
14. Reinhart, W.H. 1994, Shear-dependence of endothelial functions, Experientia 50, 87.
15. Watson, P.A. 1991, Function follows form: generation of intracellular signal by cell deformation, FASEB J. 5, 2013.
16. Wieland, T., K. Liedel, S. Kaldenberg-Stasch, D. Meyer zu Heringdorf, M. Schmidt and K.H. Jakobs, 1995, Analysis of receptor-G protein interactions in permeabilized cells, Naunyn-Schmiedeberg's Arch. Pharmacol, 351, 329.
17. Williams, A.G., M.J. Woolkalis, M. Poncz, D.R. Manning, A.M. Gewirtz and L.F. Brass, 1990, Identification of pertussis toxin-sensitive G proteins in platelets, megakaryocytes, and human erythroleukemia cells, Blood 76, 721.