Antigen delivery strategies for mucosal vaccines

International Journal for Parasitology

Volumn 26, Issue 8-9, 1996, Pages 825-834

  Husband, A J ^a   Bao, S ^a   McClure, S J ^b   Emery, D L ^b   Ramsay, A J ^c  

^a UNIVERSITY OF SYDNEY   (Australia)

^b CSIRO   (Australia)

^c NONE

Author keywords

antigen delivery; cytokines; eosinophils; IL 5; IL 6; mucosal vaccines

Indexed keywords

CYTOKINE; INTERLEUKIN 5; INTERLEUKIN 6; VACCINE;

CATTLE; CELLULAR IMMUNITY; CONFERENCE PAPER; DRUG DELIVERY SYSTEM; EOSINOPHIL; INTESTINE MUCOSA; NONHUMAN; ORAL DRUG ADMINISTRATION; PARASITOSIS; VACCINATION; VETERINARY MEDICINE;

ANIMALIA; BOS TAURUS;

EID: 0030221545     PISSN: 00207519     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0020-7519(96)80050-6     Document Type: Conference Paper

References (86)

1. Abraham E. & Shah S. 1992. Intranasal immunization with liposomes containing IL-2 enhances bacterial polysaccharide antigen-specific pulmonary secretory antibody response. The Journal of Immunology 149: 3719-3726.
2. Ahmad A., Wang C. H. & Bell R. G. 1991. A role for IgE in intestinal immunity. Expression of rapid expulsion of Trichinella spiralis in rats transfused with IgE and thoracic duct lymphocytes. The Journal of Immunology 146: 3563-3570.
3. Allan W. & Mayrhofer G. 1981. The distribution and traffic of specific homocytotropic antibody-synthesising cells in Nippostrongylus brasiliensis-infested rats. Australian Journal of Experimental Biology and Medical Science 59: 723-737.
4. Allan W. & Mayrhofer G. 1986. Potentiated IgE response in Nippostrongylus brasiliensis infected rats - sites of synthesis and traffic of cells secreting potentiated antibody. International Archives of Allergy and Applied Immunology 81: 97-103.
5. Allison A. C. & Gregoriadis G. 1974. Liposomes as immunological adjuvants. Nature 252: 252.
6. Amiri P., Haak-Frendscho M., Robbins K., McKerrow J. H., Stewart T. & Jardieu P. 1994. Anti-immunoglobulin E treatment decreases worm burden and egg production in Schistosoma mansoni-infected normal and interferon gamma knockout mice. Journal of Experimental Medicine 180: 43-51.
7. Bahr G. M. & Chedid L. 1986. Immunological activities of muramyl peptides. Federation Proceedings 45: 2541-2544.
8. Bao S., McClure S. J., Emery D. L. & Husband A. J. 1996. Interleukin-5 mRNA expressed by eosinophils and gamma/delta T cells in parasite-immune sheep. European Journal of Immunology 26: 552-556.
9. Bao S., Goldstone S. & Husband A. J. 1993. Localization of IFN-gamma and IL-6 mRNA in murine intestine by in situ hybridization. Immunology 80: 666-670.
10. Beagley K. W., Eldridge J. H., Kiyono H., Everson M. P., Koopman W. J., Honjo T. & McGhee J. R. 1988. Recombinant murine IL-5 induces high rate IgA synthesis in cycling IgA-positive Peyer's patch B cells. The Journal of Immunology 141: 2035-2042.
11. Beagley K. W., Eldridge J. H., Lee F., Kiyono H., Everson M. P., Koopman W. J., Hirano T., Kishimoto T. & McGhee J. R. 1989. Interleukins and IgA synthesis -human and murine interleukin 6 induce high rate IgA secretion in IgA-committed B cells. Journal of Experimental Medicine 169: 2133-2148.
12. Bendixsen T., Emery D. L. & Rothwell T. L. W. 1991. The effect of specific immunization or infection with Trichostrongylus colubriformis on production of eosinophil differentiation factors in guinea pigs. International Journal for Parasitology 21: 883-889.
13. Benson E. B. & Strober W. 1988. Regulation of IgA secretion by T cell clones derived from the human gastrointestinal tract. The Journal of Immunology 140: 1874-1882.
14. Bland P. W. & Warren L. G. 1986. Antigen presentation by epithelial cells of the rat small intestine. II. Selective induction of suppressor T cells. Immunology 58: 9-14.
15. Bomford R. 1980. The comparative selectivity of adjuvants for humoral and cell-mediated immunity. I. Effect on the antibody response to bovine serum albumin and sheep red blood cells of Freund's incomplete and complete adjuvants, alhydrogel, Corynebacterium parvum, Bordetella pertussis, muramyl dipeptide and saponin. Clinical and Experimental Immunology 39: 426-434.
16. Bowersock T. L., Shalaby W. S. W., Levy M., Samuels M. L., Lallone R., White M. R., Borie D. L., Lehmeyer J. & Park K. 1994. Evaluation of an orally administered vaccine, using hydrogels containing bacterial exotoxins of Pasteurella haemolytica, in cattle. American Journal of Veterinary Research 55: 502-509.
17. Bromander A., Holmgren J. & Lycke N. 1991. Cholera toxin stimulates IL-1 production and enhances antigen presentation by macrophages in vitro. The Journal of Immunology 146: 2908-2914.
18. Capron M., Bazin H., Joseph M. & Capron A. 1981. Evidence for IgE-dependent cytotoxicity by rat eosinophils. The Journal of Immunology 126: 1764.
19. Cardenas L. & Clements J. D. 1992. Oral immunization using live attenuated Salmonella spp. as carriers of foreign antigens. Clinical Microbiology Reviews 5: 328-342.
20. Chaing C.-M. & Weiner N. 1987. Gastrointestinal uptake of liposomes. I. In vitro and in situ studies. International Journal of Pharmaceutics 37: 75.
21. Chavali S. R. & Campbell J. B. 1987. Immunomodulatory effects of orally-administered saponins and non-specific resistanced against rabies infection. International Archives of Allergy and Applied Immunology 84: 129-134.
22. Clarke C. J. & Stokes C. R. 1992. The intestinal and serum humoral immune response of mice to orally administered antigens in liposomes. 2. The response to liposome-entrapped bacterial proteins. Veterinary Immunology and Immunopathology 32: 139-148.
23. Coupar B. E. H., Teo T. & Boyle D. B. 1990. Restriction endonuclease mapping of the fowlpox virus genome. Virology 179: 159-167.
24. Cox J. M., Zamb T. J. & Babiuk L. A. 1993. Bovine herpes virus 1: immune responses in mice and cattle injected with plasmid DNA. Journal of Virology 67: 5664-5667.
25. Defrance T., Vanbervliet B., Briere F., Durand I., Rousset F. & Banchereau J. 1992. Interleukin-10 and transforming growth factor-beta cooperate to induce anti-CD40 activated naive human B-cells to secrete immunoglobulin A. Journal of Experimental Medicine 175: 671-682.
26. Donnelly J. J., Ulmer J. B. & Liu M. A. 1994. Immunization with polynucleotides. A novel approach to vaccination. The Immunologist 2: 20-25.
27. Dubucquoi S., Desreumaux P., Janin A., Klein O., Goldman M., Tavernier J., Capron A. & Capron M. 1994. Interleukin 5 synthesis by eosinophils: association with granules and immunoglobulin-dependent secretion. Journal of Experimental Medicine 179: 703-708.
28. 1 induces a small increase in sIgA+ B cells regardless of the method of B cell activation. The Journal of Immunology 148: 3830-3836.
29. Eldridge J. H., Hammond C. J., Muelbroek J. A., Staas J. K., Gilley R. M. & Tice T. R. 1990. Controlled vaccine release in the gut-associated lymphoid tissues. I. Orally administered biodegradable microspheres target the Peyer's patches. Journal of Controlled Release 11: 205-214.
30. Eldridge J. H., Staas J. K., Meulbroek J. A., McGhee J. R., Tice T. T. R. & Gilley R. M. 1990b. Disseminated mucosal anti-toxin antibody responses induced through oral or intrathecal immunisation with toxoid-containing biodegradable microspheres. In: Advances in Mucosal Immunology. (Edited by MacDonald T. T., Challacombe S. J., Bland P. W., Stokes C. R., Heatley R. V. & Mowat A. M.) pp. 375-378. Kluwer Academic Publishers, Lancaster.
31. Fujii Y., Aramaki Y., Hara T., Yachi K., Kikuchi H. & Tsuchiya S. 1993. Enhancement of systemic and mucosal immune responses following oral administration of liposomes. Immunology Letters 36: 65-70.
32. Fynan E. F., Webster R. G., Fuller D. H., Haynes J. R., Santoro J. C. & Robinson H. L. 1993. DNA vaccines: protective immunizations by patenteral, mucosal, and gene-gun inoculations. Proceedings of the National Academy of Sciences of the U.S.A. 90: 11478-11482.
33. Gallagher N. D. & Foley K. E. 1970. Premature development of intrinsic factor mediated vitamin B12 absorption in the infant rat. Gut 11: 979.
34. Gallichan W. S., Johnson D. C., Graham F. L. & Rosenthal K. L. 1993. Mucosal immunity and protection after intranasal immunization with recombinant adenovirus expressing herpes simplex virus glycoprotein B. The Journal of Infectious Diseases 168: 622-629.
35. Glauert A. M., Dingle J. T. & Lucy J. A. 1962. Action of saponin in biological cell membranes. Nature 196: 953-955.
36. Hadden J. W. 1993. Immunostimulants. Immunology Today 14: 275-280.
37. Hodgkin P. D., Yamashita L. C., Seymour B., Coffman R. L. & Kehry M. R. 1991. Membranes from both Th1 and Th2 T cell clones stimulate B cell proliferation and prepare B cells for lymphokine-induced differentiation to secrete Ig. The Journal of Immunology 147: 3696-3702.
38. Holmgren J. 1981. Actions of cholera toxin and the prevention and treatment of cholera. Nature 292: 413-417.
39. Husband A. J. 1978. An immunisation model for the control of infectious enteritis. Research in Veterinary Science 25: 173-178.
40. Husband A. J. 1993. Novel vaccination strategies for the control of mucosal infection. Vaccine 11: 107-112.
41. Husband A. J. & Seaman J. T. 1979. Vaccination of piglets against Escherichia coli enteritis. The Australian Veterinary Journal 55: 435-436.
42. Husband A. J., Ben K. J. & Lascelles A. K. 1979. IgA-containing cells in the ruminant intestine following intraperitoneal and local immunization. Immunology 37: 597-601.
43. Husband A. J., Bao S., Muir W., Ramsay A. J. & Ramshaw I. A. 1994. Cytokine regulation of mucosal responses. A rational basis for new vaccine delivery strategies. Reproduction, Fertility and Development 6: 381-388.
44. Joseph M., Auriault C., Capron A., Vorng H. & Viens P. 1983. A new function for platelets: IgE-dependent killing of schistosomes. Nature 303: 810-812.
45. Karupiah G., Ramsay A. J., Ramshaw I. A. & Blanden R. V. 1992. Recombinant vaccine vector-induced protection of athymic, nude mice from influenza A virus infection. Analysis of protective mechanisms. Scandinavian Journal of Immunology 35: 99-105.
46. Kawanishi H., Saltzman L. E. & Strober W. 1983. Mechanisms regulating IgA class-specific immunoglobulin production in murine gut-associated lymphoid tissues. I. T cells derived from Peyer's patches that switch sIgM B cells to sIgA B cells in vitro. Journal of Experimental Medicine 157: 433-450.
47. King C. L., Low C. C. & Nutman T. B. 1993. IgE production in human helminth infection. Reciprocal interrelationship between IL-4 and IFN-gamma. The Journal of Immunology 150: 1873-1880.
48. Kiyono H., McGhee J. R., Kearney J. F. & Michalek S. M. 1982. Enhancement of in vitro immune responses of murine Peyer's patch cultures by concanavalin A, muramyl dipeptide and lipopolysaccharide. Scandinavian Journal of Immunology 15: 329-339.
49. Kunimoto D. Y., Harriman G. R. & Strober W. 1988. Regulation of IgA differentiation in CH12LX B cells by lymphokines. IL-4 induces membrane IgM-positive CH12LX cells to express membrane IgA and IL-5 induces membrane IgA-positive CH12LX cells to secrete IgA. The Journal of Immunology 141: 713-720.
50. Leong K. H., Ramsay A. J., Boyle D. B. & Ramshaw I. A. 1994. Selective induction of immune responses by cytokines coexpressed in recombinant fowlpox virus. Journal of Virology 68: 8125-8130.
51. Li Y. S., Dearden-Badet M.-T. & Revillard J.-P. 1993. Induction of mouse IgA B cell differentiation by phorbol ester in the absence of proliferation. Immunobiology 188: 23-35.
52. Liang X., Lamm M. E. & Nedrud J. G. 1988. Oral administration of cholera toxin - Sendai virus conjugate potentiates gut and respiratory immunity against Sendai virus. The Journal of Immunology 141: 1495-1501.
53. Lopez A. F., Sanderson C. J., Gamble J. R., Campbell H. D., Young I. G. & Vadas M. A. 1988. Recombinant human interleukin 5 is a selective activator of human eosinophil function. Journal of Experimental Medicine 167: 219-224.
54. Lycke N. & Strober W. 1989. Cholera toxin promotes B cell isotype differentiation. The Journal of Immunology 142: 3781-3787.
55. Lycke N., Severinson E. & Strober W. 1990. Cholera toxin acts synergistically with IL-4 to promote IgG1 switch differentiation. The Journal of Immunology 145: 3316-3324.
56. Lycke N., Tsuji T. & Holmgren J. 1992. The adjuvant effect of Vibrio cholerae and Escherichia coli heat labile enterotoxin is linked to their ADP-ribosyltransferase activity. European Journal of Immunology 22: 2277-2281.
57. Mason H. S., Lam D. M. & Arntzen C. J. 1992. Expression of hepatitis B surface antigen in transgenic plants. Proceedings of the National Academy of Sciences of the U.S.A. 89: 11745-11749.
58. Mayer L. & Shlien R. 1987. Evidence for function of Ia molecules on gut epithelial cells in man. Journal of Experimental Medicine 166: 1471-1483.
59. Miller H. R. P. & Jarrett W. F. H. 1971. Immune reactions in mucous membranes. I. Intestinal mast cell response during helminth expulsion in the rat. Immunology 20: 277-288.
60. Morris S. C., Madden K. B., Adamovicz J. J., Gause W. C., Hubbard B. R., Gately M. K. & Finkelman F. D. 1994. Effects of IL-12 on in vivo cytokine gene expression and Ig isotype selection. The Journal of Immunology 152: 1047-1056.
61. Mowat A. M., Maloy K. J. & Donachie A. M. 1993. Immune-stimulating complexes as adjuvants for inducing local and systemic immunity after oral immunization with protein antigens. Immunology 80: 527-534.
62. Mowat A. M., McInnes I. B. & Parrott D. M. V. 1989. Functional properties of intra-epithelial lymphocytes from mouse small intestine. IV. Investigation of the proliferative capacity of IEL using phorbol ester and calcium ionophore. Immunology 66: 398-403.
63. Mowat A. M., Donachie A. M., Reid G. & Jarrett O. 1991. Immune-stimulating complexes containing Quil A and protein antigen prime class I MHC-restricted T lymphocytes in vivo and are immunogenic by the oral route. Immunology 72: 317-322.
64. Muir W. I., Bryden W. L. & Husband A. J. 1995. Intraperitoneal immunisation promotes local intestinal immunity in chickens. Avion Pathology 24: 679-692.
65. Nash A. D., Lofthouse S. A., Barcham G. J., Jacobs H. J., Ashman K., Meeusen E. N. T., Brandon M. R. & Andrews A. E. 1993. Recombinant cytokines as immunological adjuvants. Immunology and Cell Biology 71: 367-379.
66. O'Hagan D. T., Jeffery H., McGee J. P., Davis S. S., Rahman D. & Challacombe S. J. 1992. Biodegradable microparticles as oral vaccines. Proceedings of the International Symposia on Controlled Release Bioactive Materials 19: 118-119.
67. Pappo J., Ermak T. H. & Steger H. J. 1991. Monoclonal antibody-directed targeting of fluorescent polystyrene microspheres to Peyer's patch M cells. Immunology 73: 277-280.
68. Pierce N. F. & Gowans J. L. 1975. Cellular kinetics of the intestinal response to cholera toxoid in rats. Journal of Experimental Medicine 142: 1550-1563.
69. Purkerson J, M. & Isakson P. C. 1992. Interleukin-5 (IL-5) provides a signal that is required in addition to IL-4 for isotype switching to immunoglobulin (Ig) G1 and IgE. Journal of Experimental Medicine 175: 973-982.
70. Ramsay A. J., Husband A. J., Ramshaw I. A., Bao S., Matthaei K. I., Koehler G. & Kopf M. 1994. The role of interleukin-6 in mucosal IgA antibody responses in vivo. Science 264: 561-563.
71. Roach T. I. A., Else K. J., Wakelin D., McLaren D. J. & Grencis R. K. 1991. Trichuris muris: antigen recognition and transfer of immunity in mice by IgA monoclonal antibodies. Parasite Immunology 13: 1-12.
72. Robinson H. L., Hunt L. A. & Webster R. G. 1993. Protection against a lethal influenza virus challenge by immunization with a haemagglutinin-expressing plasmid DNA. Vaccine 11: 957-960.
73. Schultz C. C., Kaufman B., Hamilton D., Hartman A., Ruiz M., Powell C. & Berman S. 1990. Cell wall structures which may be important for successful immunisation with Salmonella - Shigella hybrid vaccines. Vaccine 8: 115-120.
74. Sheldrake R. F., Husband A. J., Watson D. L. & Cripps A. W. 1984. Selective transport of serum-derived IgA into mucosal secretions. The Journal of Immunology 132: 363-368.
75. α gene. The Journal of Immunology 147: 4374-4383.
76. Stribling R., Brunette E., Liggitt D., Gaensler K. & Debs R. 1992. Aerosol gene delivery in vivo. Proceedings of the National Academy of Sciences of the U.S.A. 89: 11277-11281.
77. Tamura S., Yamanaka A., Shimohara M., Tomita T., Komase K., Tsuda Y., Suzuki Y., Nagamine T., Kawahara K., Danbara H., Aizawa C., Oya A. & Kurata T. 1994. Synergistic action of cholera toxin B subunit (and Escherichia coli heat-labile toxin B subunit) and a trace amount of cholera whole toxin as an adjuvant for nasal influenza vaccine. Vaccine 12: 419-426.
78. Tauchi Y., Yamada A., Kawakita T., Saito Y., Suzuki A., Yoshikai Y. & Nomoto K. 1993. Enhancement of immunoglobulin A production in Peyer's patches by oral administration of a traditional Chinese medicine, xiao-chai-hu-tang (shosaiko-to). Immunopharmacology and Immunotoxicology 15: 251-272.
79. Urban J. F. Jr., Madden K. B., Cheever A. W., Trotta P. P., Katona I. M. & Finkelman F. D. 1993. IFN inhibits inflammatory responses and protective immunity in mice infected with the nematode parasite Nippostrongylus brasiliensis. The Journal of Immunology 151: 7086-7094.
80. Wang B., Ugen K. E., Srikantan V., Agadjanyan M. G., Dnag K., Rafaeli Y., Sato A. I., Boyer J., Williams W. V. & Weiner D. B. 1993. Gene inoculation generates immune responses against human immunodeficiency virus. Proceedings of the National Academy of Sciences of the U.S.A. 90: 4156-4160.
81. Watts P. J., Davies M. C. & Melia C. D. 1990. Microencapsulation using emulsification/solvent evaporation: an overview of techniques and applications. Critical Reviews in Therapeutic Drug Carrier Systems 7: 235-259.
82. Wilson A. D., Clarke C. J. & Stokes C. R. 1993. Adjuvant action of cholera toxin and pertussis toxin in the induction of IgA antibody response to orally administered antigen. Vaccine 11: 113-118.
83. Wu H.-Y. & Russell M. W. 1994. Comparison of systemic and mucosal priming for mucosal immune responses to a bacterial protein antigen given with or coupled to cholera toxin (CT) B subunit, and effects of pre-existing anti-CT immunity. Vaccine 12: 215-222.
84. Yamada M., Uchikawa R., Nakazawa M., Oda M. & Arizono N. 1993. Dissociation of specific and total IgE antibody responses following repeated low-level infections with Nippostrongylus brasiliensis in rats. Clinical and Experimental Immunology 93: 80-84.
85. Yamaguchi Y., Suda T., Suda J., Eguchi M., Miura Y., Harada N., Tominaga A. & Takatsu K. 1988. Purified interleukin 5 supports the terminal differentiation and proliferation of murine eosinophil precursors. Journal of Experimental Medicine 167: 43-56.
86. Yoo Y. C., Saiki I., Sato K. & Azuma I. 1994. MDP-Lys(L18), a lipophilic derivative of muramyl dipeptide, inhibits the metastasis of haematogenous and non-haematogenous tumours in mice. Vaccine 12: 175-180.